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A. Christoffels · SciRah

Researcher profile · Semantic Scholar

A. Christoffels

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A. Christoffels — researcher profile on SciRah

h-index: 35
Works: 149
Citations: 11K

Most-cited papers

Enabling the genomic revolution in Africa
C. Rotimi, Akin Abayomi, A. Abimiku, V. Adabayeri +241 more
2014Science305 citations Open access
Semantic Scholar
Genome Sequence of the Tsetse Fly (Glossina morsitans): Vector of African Trypanosomiasis
G. M. Attardo, P. P. Abila, J. E. Auma, A. Baumann +133 more
2014Science260 citations Open access
Semantic Scholar
Chromosomal-Level Assembly of the Asian Seabass Genome Using Long Sequence Reads and Multi-layered Scaffolding
S. Vij, H. Kuhl, I. Kuznetsova, Aleksey Komissarov +44 more
2016PLoS Genetics197 citations Open access
Semantic Scholar
Whole-genome sequencing for an enhanced understanding of genetic variation among South Africans
A. Choudhury, M. Ramsay, S. Hazelhurst, S. Aron +17 more
2017Nature Communications116 citations Open access
Semantic Scholar
Evidence for a common biological pathway linking three Parkinson's disease‐causing genes: parkin, PINK1 and DJ‐1
C. van der Merwe, Zahra Jalali Sefid Dashti, A. Christoffels, B. Loos +1 more
2015European Journal of Neuroscience106 citations
Semantic Scholar
Gonad Differentiation in Zebrafish Is Regulated by the Canonical Wnt Signaling Pathway1
R. Sreenivasan, Junhui Jiang, Xingang Wang, R. Bártfai +3 more
2014Biology of Reproduction104 citations Open access
Semantic Scholar
Towards inferring the global movement of beak and feather disease virus.
G. Harkins, Darren P. Martin, A. Christoffels, A. Varsani
2014Virology69 citations Open access
Semantic Scholar
Inhibiting CDK6 Activity by Quercetin Is an Attractive Strategy for Cancer Therapy
M. Yousuf, Parvez Khan, Anas Shamsi, Mohd Shahbaaz +5 more
2020ACS Omega68 citations Open access
Semantic Scholar
A genomics network established to respond rapidly to public health threats in South Africa
N. Msomi, K. Mlisana, T. de Oliveira, Carolyn Willianson +18 more
2020The Lancet Microbe52 citations Open access
Semantic Scholar
Designing novel possible kinase inhibitor derivatives as therapeutics against Mycobacterium tuberculosis: An in silico study
Mohd Shahbaaz, Anati N. Nkaule, A. Christoffels
2019Scientific Reports42 citations Open access
Semantic Scholar
Genome-Wide Comparative Analysis of Chemosensory Gene Families in Five Tsetse Fly Species
R. Macharia, P. Mireji, Edwin Murungi, G. Murilla +3 more
2016PLoS Neglected Tropical Diseases41 citations Open access
Semantic Scholar
Prioritization of anti-malarial hits from nature: chemo-informatic profiling of natural products with in vitro antiplasmodial activities and currently registered anti-malarial drugs
S. Egieyeh, J. Syce, S. Malan, A. Christoffels
2016Malaria Journal40 citations Open access
Semantic Scholar
A glance at quality score: implication for de novo transcriptome reconstruction of Illumina reads
Stanley Kimbung Mbandi, U. Hesse, D. J. G. Rees, A. Christoffels
2014Frontiers in Genetics39 citations Open access
Semantic Scholar
Future-proofing and maximizing the utility of metadata: The PHA4GE SARS-CoV-2 contextual data specification package
E. Griffiths, R. Timme, C. Mendes, A. Page +29 more
2022GigaScience37 citations Open access
Semantic Scholar
Corrigendum: POPIA Code of Conduct for Research
R. Adams, F. Adeleke, Dominique Anderson, Ahmed Bawa +19 more
2021South African Journal of Science37 citations Open access
Semantic Scholar
Prediction of human-Bacillus anthracis protein–protein interactions using multi-layer neural network
Ibrahim H. I. Ahmed, P. Witbooi, A. Christoffels
2018Bioinform.36 citations Open access
Semantic Scholar
Taste and odorant receptors of the coelacanth--a gene repertoire in transition.
Barbara Picone, U. Hesse, Sumir Panji, P. van Heusden +2 more
2014Journal of Experimental Zoology Part B: Molecular and Developmental Evolution35 citations
Semantic Scholar
Predictive classifier models built from natural products with antimalarial bioactivity using machine learning approach
S. Egieyeh, J. Syce, S. Malan, A. Christoffels
2018PLoS ONE33 citations Open access
Semantic Scholar
Accelerating genomics-based surveillance for COVID-19 response in Africa
S. Tessema, S. Inzaule, A. Christoffels, Y. Kebede +4 more
2020The Lancet Microbe29 citations Open access
Semantic Scholar
Resistance related metabolic pathways for drug target identification in Mycobacterium tuberculosis
Ruben Cloete, Ekow Oppon, Edwin Murungi, W. Schubert +1 more
2016BMC Bioinformatics29 citations Open access
Semantic Scholar
Molecular modelling and simulation studies of the Mycobacterium tuberculosis multidrug efflux pump protein Rv1258c
Ruben Cloete, E. Kapp, J. Joubert, A. Christoffels +1 more
2018PLoS ONE27 citations Open access
Semantic Scholar
Baobab Laboratory Information Management System: Development of an Open-Source Laboratory Information Management System for Biobanking
Hocine Bendou, Lunga Sizani, Timothy Reid, Carmen Swanepoel +5 more
2017Biopreservation and Biobanking25 citations Open access
Semantic Scholar
A pan-African pathogen genomics data sharing platform to support disease outbreaks
A. Christoffels, Gerald Mboowa, P. van Heusden, Sello Makhubela +18 more
2023Nature Medicine24 citations Open access
Semantic Scholar
An integrated and comparative approach towards identification, characterization and functional annotation of candidate genes for drought tolerance in sorghum (Sorghum bicolor (L.) Moench)
A. Woldesemayat, P. van Heusden, B. Ndimba, A. Christoffels
2017BMC Genetics24 citations Open access
Semantic Scholar
Supporting the development of biobanks in low and medium income countries
Tomas Klingstrom, Maimuna Mendy, D. Meunier, Anouk Berger +14 more
2016IST-Africa Week Conference24 citations
Semantic Scholar
Cheminformatic Characterization of Natural Antimicrobial Products for the Development of New Lead Compounds
S. O. Oselusi, A. Christoffels, S. Egieyeh
2021Molecules23 citations Open access
Semantic Scholar
Cross-species multiple environmental stress responses: An integrated approach to identify candidate genes for multiple stress tolerance in sorghum (Sorghum bicolor (L.) Moench) and related model species
A. Woldesemayat, D. Modise, Junaid Gemeildien, B. Ndimba +1 more
2018PLoS ONE22 citations Open access
Semantic Scholar
The Development of Computational Biology in South Africa: Successes Achieved and Lessons Learnt
N. Mulder, A. Christoffels, T. de Oliveira, J. Gamieldien +7 more
2016PLoS Comput. Biol.21 citations Open access
Semantic Scholar
Genomic surveillance of Rift Valley fever virus: from sequencing to lineage assignment
J. Juma, V. Fonseca, S. Konongoi, P. van Heusden +6 more
2022BMC Genomics19 citations Open access
Semantic Scholar
The PHA4GE SARS-CoV-2 Contextual Data Specification for Open Genomic Epidemiology
Emma J. Griffiths, R. Timme, Andrew J. Page, N. Alikhan +22 more
202019 citations Open access
Semantic Scholar
A comparative analysis of trypanosomatid SNARE proteins
Edwin Murungi, L. Barlow, D. Venkatesh, V. Adung’a +3 more
2014Parasitology international18 citations Open access
Semantic Scholar
High Resolution HLA ∼A, ∼B, ∼C, ∼DRB1, ∼DQA1, and ∼DQB1 Diversity in South African Populations
M. Tshabalala, J. Mellet, Kuben Vather, Derrick Nelson +3 more
2022Frontiers in Genetics16 citations Open access
Semantic Scholar
Evaluation of Protein Purification Techniques and Effects of Storage Duration on LC-MS/MS Analysis of Archived FFPE Human CRC Tissues
S. Rossouw, Hocine Bendou, R. Blignaut, L. Bell +2 more
2021Pathology and Oncology Research16 citations Open access
Semantic Scholar
Upregulation of FHL1, SPNS3, and MPZL2 predicts poor prognosis in pediatric acute myeloid leukemia patients with FLT3-ITD mutation
N. Eshibona, A. Giwa, S. Rossouw, J. Gamieldien +2 more
2022Leukemia and Lymphoma15 citations Open access
Semantic Scholar
Cheminformatic Profiling and Hit Prioritization of Natural Products with Activities against Methicillin-Resistant Staphylococcus aureus (MRSA)
S. O. Oselusi, S. Egieyeh, A. Christoffels
2021Molecules15 citations Open access
Semantic Scholar
Accessing Biospecimens from the H3Africa Consortium
C. Beiswanger, A. Abimiku, N. Carstens, A. Christoffels +8 more
2017Biopreservation and Biobanking15 citations Open access
Semantic Scholar
Correction: Chromosomal-Level Assembly of the Asian Seabass Genome Using Long Sequence Reads and Multi-layered Scaffolding
S. Vij, H. Kuhl, I. Kuznetsova, Aleksey Komissarov +44 more
2016PLoS Genetics15 citations Open access
Semantic Scholar
Structural and functional effects of nucleotide variation on the human TB drug metabolizing enzyme arylamine N-acetyltransferase 1.
Ruben Cloete, Wisdom A. Akurugu, C. Werely, P. van Helden +1 more
2017Journal of Molecular Graphics and Modelling14 citations Open access
Semantic Scholar
Prioritization of candidate genes for a South African family with Parkinson’s disease using in-silico tools
Boiketlo Sebate, Katelyn Cuttler, Ruben Cloete, M. Britz +4 more
2021PLoS ONE13 citations Open access
Semantic Scholar
Selecting a Laboratory Information Management System for Biorepositories in Low- and Middle-Income Countries: The H3Africa Experience and Lessons Learned
Samuel Kyobe, H. Musinguzi, Newton Lwanga, Dafala Kezimbira +15 more
2017Biopreservation and Biobanking13 citations Open access
Semantic Scholar
Using Multiplex Amplicon PCR Technology to Efficiently and Timely Generate Rift Valley Fever Virus Sequence Data for Genomic Surveillance
J. Juma, S. Konongoi, Isidore Nsengimana, Reuben Mwangi +13 more
2023Viruses12 citations Open access
Semantic Scholar
Identification of novel prognostic markers of survival time in high-risk neuroblastoma using gene expression profiles
A. Giwa, A. Fatai, J. Gamieldien, A. Christoffels +1 more
2020OncoTarget12 citations Open access
Semantic Scholar
Identification and characterization of microRNAs expressed in the African malaria vector Anopheles funestus life stages using high throughput sequencing
Mushal Allam, B. Spillings, H. Abdalla, D. Mapiye +2 more
2016Malaria Journal12 citations Open access
Semantic Scholar
Investigation of distinct gene expression profile patterns that can improve the classification of intermediate-risk prognosis in AML patients
N. Eshibona, Michelle Livesey, A. Christoffels, Hocine Bendou
2023Frontiers in Genetics11 citations Open access
Semantic Scholar
Human African Trypanosomiasis Research Gets a Boost: Unraveling the Tsetse Genome
S. Aksoy, G. Attardo, M. Berriman, A. Christoffels +3 more
2014PLoS Neglected Tropical Diseases11 citations Open access
Semantic Scholar
A population model for the 2017/18 listeriosis outbreak in South Africa
P. Witbooi, C. Africa, A. Christoffels, Ibrahim H. I. Ahmed
2020PLoS ONE10 citations Open access
Semantic Scholar
COMBAT-TB-NeoDB: fostering tuberculosis research through integrative analysis using graph database technologies
T. Lose, P. van Heusden, A. Christoffels
2019Bioinform.10 citations Open access
Semantic Scholar
Human Leukocyte Antigen-A, B, C, DRB1, and DQB1 Allele and Haplotype Frequencies in a Subset of 237 Donors in the South African Bone Marrow Registry
M. Tshabalala, C. Ingram, T. Schlaphoff, V. Borrill +2 more
2018Journal of Immunological Research10 citations Open access
Semantic Scholar
The PHA4GE Microbial Data-Sharing Accord: establishing baseline consensus microbial data-sharing norms to facilitate cross-sectoral collaboration
Emma J. Griffiths, P. van Heusden, T. Tamuhla, Eddie T Lulamba +4 more
2024BMJ Global Health9 citations Open access
Semantic Scholar
Transforming RNA-Seq gene expression to track cancer progression in the multi-stage early to advanced-stage cancer development
Michelle Livesey, S. Rossouw, R. Blignaut, A. Christoffels +1 more
2023PLoS ONE9 citations Open access
Semantic Scholar

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