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Hongzhen Zhang · SciRah

Researcher profile · Semantic Scholar

Hongzhen Zhang

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Hongzhen Zhang — researcher profile on SciRah

h-index: 27
Works: 67
Citations: 11K

Most-cited papers

The Immune Landscape of Cancer
V. Thorsson, D. Gibbs, S. Brown, D. Wolf +496 more
2018Immunity4,928 citations Open access
Semantic Scholar
Oncogenic Signaling Pathways in The Cancer Genome Atlas
F. Sánchez-Vega, M. Mina, J. Armenia, W. Chatila +496 more
2018Cell2,752 citations Open access
Semantic Scholar
Comprehensive Characterization of Cancer Driver Genes and Mutations
M. Bailey, C. Tokheim, E. Porta-Pardo, Sohini Sengupta +496 more
2018Cell2,066 citations Open access
Semantic Scholar
Luteolin nanoparticle in chemoprevention – in vitro and in vivo anticancer activity
Debatosh Majumdar, K. Jung, Hongzhen Zhang, S. Nannapaneni +5 more
2014Cancer Prevention Research158 citations Open access
Semantic Scholar
Integrative Genomic Analysis of Cholangiocarcinoma Identifies Distinct IDH-Mutant Molecular Profiles
V. Cardinale, E. Gaudio, D. Alvaro, A. Franchitto +196 more
2017Cell Reports146 citations Open access
Semantic Scholar
Label-free reflectance hyperspectral imaging for tumor margin assessment: a pilot study on surgical specimens of cancer patients
B. Fei, G. Lu, Xu Wang, Hongzhen Zhang +5 more
2017Journal of Biomedical Optics117 citations Open access
Semantic Scholar
Detection of Head and Neck Cancer in Surgical Specimens Using Quantitative Hyperspectral Imaging
G. Lu, James V. Little, Xu Wang, Hongzhen Zhang +5 more
2017Clinical Cancer Research115 citations Open access
Semantic Scholar
Synergistic inhibition of head and neck tumor growth by green tea (−)-epigallocatechin-3-gallate and EGFR tyrosine kinase inhibitor
Xin Zhang, Hongzhen Zhang, M. Tighiouart, John E. Lee +5 more
2008International Journal of Cancer109 citations Open access
Semantic Scholar
Enhanced Anti-tumor Activity by the Combination of the Natural Compounds (−)-Epigallocatechin-3-gallate and Luteolin
A. R. R. Ruhul Amin, Dong-Sheng Wang, Hongzhen Zhang, S. Peng +6 more
2010Journal of Biological Chemistry107 citations Open access
Semantic Scholar
HPV16 E6 and E7 proteins induce a chronic oxidative stress response via NOX2 that causes genomic instability and increased susceptibility to DNA damage in head and neck cancer cells.
R. Marullo, Erica Werner, Hongzhen Zhang, G. Chen +2 more
2015Carcinogenesis85 citations Open access
Semantic Scholar
Distinctive E‐cadherin and epidermal growth factor receptor expression in metastatic and nonmetastatic head and neck squamous cell carcinoma
S. Muller, Ling Su, M. Tighiouart, N. Saba +3 more
2008Cancer76 citations Open access
Semantic Scholar
Detection of Cancer Metastasis Using a Novel Macroscopic Hyperspectral Method
H. Akbari, Luma V. Halig, Hongzhen Zhang, Dong-Sheng Wang +2 more
2012Medical Imaging69 citations Open access
Semantic Scholar
HER3 targeting sensitizes HNSCC to cetuximab by reducing HER3 activity and HER2/HER3 dimerization - evidence from cell line and patient derived xenograft models
Dong-Sheng Wang, G. Qian, Hongzhen Zhang, K. Magliocca +11 more
2016Clinical Cancer Research58 citations Open access
Semantic Scholar
Restoration of caveolin-1 expression suppresses growth and metastasis of head and neck squamous cell carcinoma
Hongzhen Zhang, Ling Su, Susan Muller, M. Tighiouart +7 more
2008British Journal of Cancer58 citations Open access
Semantic Scholar
Chemoprevention of Head and Neck Cancer by Simultaneous Blocking of Epidermal Growth Factor Receptor and Cyclooxygenase-2 Signaling Pathways: Preclinical and Clinical Studies
Dong M. Shin, Hongzhen Zhang, N. Saba, Amy Y. Chen +16 more
2013Clinical Cancer Research57 citations Open access
Semantic Scholar
Combination of Anti-HER3 Antibody MM-121/SAR256212 and Cetuximab Inhibits Tumor Growth in Preclinical Models of Head and Neck Squamous Cell Carcinoma (HNSCC)
Ning Jiang, Dong-Sheng Wang, Zhongliang Hu, H. J. Shin +14 more
2014Molecular Cancer Therapeutics56 citations Open access
Semantic Scholar
Somatostatin Receptor-Based Molecular Imaging and Therapy for Neuroendocrine Tumors
Ling Wang, K. Tang, Qi Zhang, Huan-Liang Li +3 more
2013BioMed Research International56 citations Open access
Semantic Scholar
Framework for hyperspectral image processing and quantification for cancer detection during animal tumor surgery
G. Lu, Dong-Sheng Wang, Xulei Qin, Luma V. Halig +6 more
2015Journal of Biomedical Optics55 citations Open access
Semantic Scholar
Downregulation of E-Cadherin enhances proliferation of head and neck cancer through transcriptional regulation of EGFR
Dong-Sheng Wang, Ling Su, Dong-Hai Huang, Hongzhen Zhang +2 more
2011Molecular Cancer53 citations Open access
Semantic Scholar
A dual‐targeting antibody against EGFR‐VEGF for lung and head and neck cancer treatment
Hongzhen Zhang, Su-Jin Yun, Thil D. Batuwangala, M. Steward +11 more
2012International Journal of Cancer38 citations Open access
Semantic Scholar
Synthetic curcumin analog EF31 inhibits the growth of head and neck squamous cell carcinoma xenografts
Shijun Zhu, T. Moore, Xiaoqian Lin, Nao Morii +15 more
2012Integrative Biology37 citations Open access
Semantic Scholar
Understanding metastatic SCCHN cells from unique genotypes to phenotypes with the aid of an animal model and DNA microarray analysis
Xin Zhang, Ling Su, A. Pirani, Haiyan Wu +4 more
2006Clinical and Experimental Metastasis35 citations
Semantic Scholar
Factors Associated With Hospital Length of Stay Following Fibular Free-Tissue Reconstruction of Head and Neck Defects: Assessment Using the American College of Surgeons National Surgical Quality Improvement Program (ACS NSQIP) Criteria.
Laura J. White, Hongzhen Zhang, Kaitlyn F. Strickland, M. El-Deiry +3 more
2015JAMA Otolaryngology - Head and Neck Surgery31 citations Open access
Semantic Scholar
HPV16 oncoprotein regulates the translocation of β-catenin via activation of EGFR
Zhongliang Hu, Susan Müller, G. Qian, Jing Xu +8 more
2014Cancer31 citations Open access
Semantic Scholar
Pharmacokinetic-directed high-dose busulfan combined with cyclophosphamide and etoposide results in predictable drug levels and durable long-term survival in lymphoma patients undergoing autologous stem cell transplantation.
Hongzhen Zhang, M. Graiser, D. Hutcherson, M. Dada +4 more
2012Biology of Blood and Marrow Transplantation30 citations Open access
Semantic Scholar
Hyperspectral Imaging of Neoplastic Progression in a Mouse Model of Oral Carcinogenesis
G. Lu, Xulei Qin, Dong-Sheng Wang, S. Muller +4 more
2016SPIE Medical Imaging28 citations Open access
Semantic Scholar
Quantum dot-based quantification revealed differences in subcellular localization of EGFR and E-cadherin between EGFR-TKI sensitive and insensitive cancer cells
Dong-Hai Huang, Ling Su, Xiang-Hong Peng, Hongzhen Zhang +3 more
2009Nanotechnology28 citations Open access
Semantic Scholar
Label-Free Hyperspectral Imaging and Quantification Methods for Surgical Margin Assessment of Tissue Specimens of Cancer Patients
B. Fei, G. Lu, M. Halicek, Xu Wang +7 more
2017Annual International Conference of the IEEE Engineering in Medicine and Biology Society17 citations Open access
Semantic Scholar
Biomarker quantification by multiplexed quantum dot technology for predicting lymph node metastasis and prognosis in head and neck cancer
Zhongliang Hu, G. Qian, Susan Müller, Jing Xu +10 more
2016OncoTarget14 citations Open access
Semantic Scholar
Tumor margin assessment of surgical tissue specimen of cancer patients using label-free hyperspectral imaging
B. Fei, G. Lu, Xu Wang, Hongzhen Zhang +3 more
2017BiOS13 citations Open access
Semantic Scholar
Synthetic curcumin analog UBS109 inhibits the growth of head and neck squamous cell carcinoma xenografts.
Shijun Zhu, T. Moore, Nao Morii, R. Howard +13 more
2014Current Cancer Drug Targets12 citations
Semantic Scholar
Initial management strategies for follicular lymphoma
Qiushi Chen, T. Ayer, L. Nastoupil, Miray Seward +3 more
2012International Journal of Hematologic Oncology11 citations Open access
Semantic Scholar
The Lung Immune Prognostic Index May Predict the Efficacy of Different Treatments in Patients with Advanced NSCLC: A Meta-Analysis
Jianhua Xie, Yu-Qin Zang, Miaomiao Liu, Li-Li Peng +1 more
2021Oncology Research and Treatment10 citations Open access
Semantic Scholar
HPV 16 E 6 and E 7 proteins induce a chronic oxidative stress response via NOX 2 that causes genomic instability and increased susceptibility to DNA damage in head and neck cancer cells
R. Marullo, Erica Werner, Hongzhen Zhang, Chen +2 more
20159 citations
Semantic Scholar
Prognostic biomarkers in patients with human immunodeficiency virus-positive disease with head and neck squamous cell carcinoma
Hongzhen Zhang, Sungjin Kim, Zheng-Jia Chen, S. Nannapaneni +27 more
2017Head and Neck8 citations Open access
Semantic Scholar
Procedure for developing linear and Bayesian classification models based on immunosensor measurements
Stephen Mobley, S. Yalamanchili, Hongzhen Zhang, R. Marullo +5 more
20148 citations
Semantic Scholar
Pharmacodynamics of DT-IgG, a dual-targeting antibody against VEGF-EGFR, in tumor xenografted mice
S. Hurwitz, Hongzhen Zhang, Su-Jin Yun, T. Batuwangala +10 more
2012Cancer Chemotherapy and Pharmacology8 citations
Semantic Scholar
Association of three promoter polymorphisms in interleukin-10 gene with cancer susceptibility in the Chinese population: a meta-analysis
Ping Wang, Jun-Ling An, Yanfeng Zhu, Xue-Dong Wan +3 more
2017OncoTarget6 citations Open access
Semantic Scholar
A novel prediction model for human papillomavirus-associated oropharyngeal squamous cell carcinoma using p16 and subcellular β-catenin expression
G. Qian, Zhongliang Hu, Hong Xu, Susan Müller +8 more
2015Journal of Oral Pathology & Medicine5 citations Open access
Semantic Scholar
Quantitative Diagnosis of Tongue Cancer from Histological Images in an Animal Model
G. Lu, Xulei Qin, Dong-Sheng Wang, S. Muller +4 more
2016SPIE Medical Imaging4 citations Open access
Semantic Scholar
[HUVECs extraction and UHPLC LTQ Orbitrap analysis for screening vascular endothelium protective components in Kudiezi injection].
Si-Yi Liu, Hongzhen Zhang, Jing Fan, Zhan-Peng Shang +5 more
2017Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica1 citations
Semantic Scholar
Dual targeting of EGFR and HER3 with cetuximab and MM-121/SAR256212 in HNSCC patient derived xenograft (PDX) models.
N. Saba, Dong-Sheng Wang, Guoquing Qian, Hongzhen Zhang +8 more
20151 citations
Semantic Scholar
Enhanced anti-tumor activity by the combination of the natural compounds (-)-epigallocatechin-3-gallate and luteolin.
A. R. R. Ruhul Amin, Dongsheng Wang, Hongzhen Zhang, S. Peng +6 more
2025Journal of Biological Chemistry0 citations Open access
Semantic Scholar
The prognostic significance of ALI, PLR, and Ki-67 expression in stage III-IV inoperable non-small cell lung cancer
Ying Li, Qiaofang Li, Ya-Ni He, Hongzhen Zhang
2021Oncology and Translational Medicine0 citations Open access
Semantic Scholar
Abstract P1-06-01: Regulation of BRCA1 by SIRT2
Elizabeth V. Minten, Hongzhen Zhang, Chunyang Li, PamelaSara E. Head +1 more
2019Poster Session Abstracts0 citations
Semantic Scholar
Abstract 1866: HER3 targeting sensitizes HNSCC to cetuximab - evidence from cell line and patient derived xenograft (PDX) models
Dong-Sheng Wang, G. Qian, Hongzhen Zhang, K. Magliocca +9 more
20160 citations
Semantic Scholar
An integrated workflow to identify targetable mutations in FFPE samples of HNSCC.
N. Saba, K. Magliocca, M. Patel, C. Steuer +8 more
20160 citations
Semantic Scholar
Landscape of genetic alterations in non-smoking patients with oral tongue carcinoma: An analysis of The Cancer Genome Atlas (TCGA) head and neck squamous cell carcinoma data.
N. Saba, Scott Newman, M. Rossi, C. Steuer +9 more
20150 citations
Semantic Scholar
Large Molecule Therapeutics Combination of Anti-HER 3 Antibody MM-121 / SAR 256212 and Cetuximab Inhibits Tumor Growth in Preclinical Models of Head and Neck Squamous Cell Carcinoma
Ning-Ning Jiang, Dong-Sheng Wang, Zhongliang Hu, H. J. Shin +14 more
20140 citations
Semantic Scholar
Abstract 1852: Enhancing specificity in predication of human papillomavirus associated oropharyngeal squamous cell carcinoma by combining biomarkers p16 and β-catenin
G. Qian, Hong Xu, Zhongliang Hu, Sungjin Kim +8 more
20140 citations
Semantic Scholar

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