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W. Risau · SciRah

Researcher profile · Semantic Scholar

W. Risau

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W. Risau — researcher profile on SciRah

h-index: 90
Works: 174
Citations: 48K

Most-cited papers

Mechanisms of angiogenesis
W. Risau
1997Nature6,075 citations
Semantic Scholar
Abnormal blood vessel development and lethality in embryos lacking a single VEGF allele
P. Carmeliet, Valérie Ferreira, G. Breier, S. Pollefeyt +12 more
1996Nature4,418 citations
Semantic Scholar
Distinct roles of the receptor tyrosine kinases Tie-1 and Tie-2 in blood vessel formation
Thomas N. Sato, Y. Tozawa, U. Deutsch, K. Wolburg-Buchholz +6 more
1995Nature1,914 citations
Semantic Scholar
Vascular Endothelial Growth Factor Induces Endothelial Fenestrations In Vitro
S. Esser, Karen Wolburg, H. Wolburg, Georg Breier +2 more
1998Journal of Cell Biology1,239 citations Open access
Semantic Scholar
SU5416 is a potent and selective inhibitor of the vascular endothelial growth factor receptor (Flk-1/KDR) that inhibits tyrosine kinase catalysis, tumor vascularization, and growth of multiple tumor types.
A. Fong, L. Shawver, Li Sun, Cho Tang +9 more
1999Cancer Research1,132 citations
Semantic Scholar
Roles of ephrinB ligands and EphB receptors in cardiovascular development: demarcation of arterial/venous domains, vascular morphogenesis, and sprouting angiogenesis.
R. Adams, George A. Wilkinson, Cornelia Weiss, F. Diella +4 more
1999Genes & Development1,091 citations Open access
Semantic Scholar
Role of tissue factor in embryonic blood vessel development
P. Carmeliet, N. Mackman, L. Moons, T. Luther +10 more
1996Nature750 citations
Semantic Scholar
Hypoxia-induced vascular endothelial growth factor expression precedes neovascularization after cerebral ischemia.
Hugo H. Marti, M. Bernaudin, A. Bellail, H. Schoch +3 more
2000American Journal of Pathology695 citations Open access
Semantic Scholar
Differentiation of endothelium
W. Risau
1995The FASEB Journal660 citations
Semantic Scholar
Hypoxia-induced Transcriptional Activation and Increased mRNA Stability of Vascular Endothelial Growth Factor in C6 Glioma Cells (*)
E. Ikeda, M. G. Achen, G. Breier, W. Risau
1995Journal of Biological Chemistry642 citations Open access
Semantic Scholar
The Vascular Endothelial Growth Factor Receptor Flt-1 Mediates Biological Activities
M. Clauss, H. Weich, G. Breier, U. Knies +3 more
1996Journal of Biological Chemistry626 citations Open access
Semantic Scholar
Uniform vascular-endothelial-cell-specific gene expression in both embryonic and adult transgenic mice.
T. Schlaeger, S. Bartunkova, J. Lawitts, G. Teichmann +3 more
1997Proceedings of the National Academy of Sciences of the United States of America534 citations Open access
Semantic Scholar
Cell type-specific expression of angiopoietin-1 and angiopoietin-2 suggests a role in glioblastoma angiogenesis.
A. Stratmann, W. Risau, K. Plate
1998American Journal of Pathology502 citations Open access
Semantic Scholar
Angiopoietin-1 induces sprouting angiogenesis in vitro.
T. Koblizek, Cornelia Weiss, G. Yancopouloš, U. Deutsch +1 more
1998Current Biology483 citations Open access
Semantic Scholar
Localization of claudin-3 in tight junctions of the blood-brain barrier is selectively lost during experimental autoimmune encephalomyelitis and human glioblastoma multiforme
H. Wolburg, K. Wolburg-Buchholz, J. Kraus, Gesa Rascher-Eggstein +6 more
2003Acta Neuropathologica467 citations
Semantic Scholar
Systemic hypoxia changes the organ-specific distribution of vascular endothelial growth factor and its receptors.
Hugo H. Marti, W. Risau
1998Proceedings of the National Academy of Sciences of the United States of America452 citations Open access
Semantic Scholar
Dominant-negative inhibition of Flk-1 suppresses the growth of many tumor types in vivo.
Birgit Millauer, M. Longhi, K. Plate, L. Shawver +3 more
1996Cancer Research446 citations
Semantic Scholar
Molecular mechanisms of vasculogenesis and embryonic angiogenesis
I. Flamme, T. Frölich, W. Risau
1997Journal of Cellular Physiology438 citations
Semantic Scholar
HRF, a putative basic helix-loop-helix-PAS-domain transcription factor is closely related to hypoxia-inducible factor-1 alpha and developmentally expressed in blood vessels.
I. Flamme, Thomas Fröhlich, Marie von Reutern, Andreas Kappel +2 more
1997Mechanisms of Development414 citations Open access
Semantic Scholar
Flk-1 expression defines a population of early embryonic hematopoietic precursors.
N. Kabrun, H. Bühring, Kyunghee Choi, A. Ullrich +2 more
1997Development387 citations
Semantic Scholar
Angiogenesis in malignant gliomas
K. Plate, W. Risau
1995Glia351 citations
Semantic Scholar
Up-regulation of vascular endothelial growth factor and its receptors in von Hippel-Lindau disease-associated and sporadic hemangioblastomas.
S. Wizigmann-Voos, G. Breier, W. Risau, K. Plate
1995Cancer Research350 citations
Semantic Scholar
Molecular cloning and expression of murine vascular endothelial-cadherin in early stage development of cardiovascular system.
G. Breier, F. Breviario, L. Caveda, R. Berthier +5 more
1996Blood348 citations Open access
Semantic Scholar
Flk-1 as a target for tumor growth inhibition.
L. M. Strawn, G. Mcmahon, H. App, R. Schreck +14 more
1996Cancer Research340 citations
Semantic Scholar
Cell confluence regulates tyrosine phosphorylation of adherens junction components in endothelial cells.
M. Lampugnani, M. Corada, P. Andriopoulou, S. Esser +2 more
1997Journal of Cell Science316 citations
Semantic Scholar
Expression of vascular endothelial growth factor and its receptors in human renal ontogenesis and in adult kidney.
M. Simon, H. Grone, O. Jöhren, J. Kullmer +3 more
1995American Journal of Physiology313 citations
Semantic Scholar
Coordinate expression of vascular endothelial growth factor receptor‐1 (fit‐1) and its ligand suggests a paracrine regulation of murine vascular development
G. Breier, M. Clauss, W. Risau
1995Developmental Dynamics305 citations
Semantic Scholar
Vascular endothelial growth factor (VEGF) and VEGF receptor 2 (flk-1) are expressed during vasculogenesis and vascular differentiation in the quail embryo.
I. Flamme, G. Breier, W. Risau
1995Developmental Biology278 citations Open access
Semantic Scholar
Identification of vascular endothelial growth factor (VEGF) receptor-2 (Flk-1) promoter/enhancer sequences sufficient for angioblast and endothelial cell-specific transcription in transgenic mice.
Andreas Kappel, Volker Rönicke, A. Damert, I. Flamme +2 more
1999Blood246 citations
Semantic Scholar
Expressions of PDGF receptor alpha, c‐Kit and Flk1 genes clustering in mouse chromosome 5 define distinct subsets of nascent mesodermal cells
H. Kataoka, N. Takakura, Satomi Nishikawa, K. Tsuchida +5 more
1997Development, Growth and Differentiation238 citations
Semantic Scholar
Activator-protein-1 binding potentiates the hypoxia-induciblefactor-1-mediated hypoxia-induced transcriptional activation of vascular-endothelial growth factor expression in C6 glioma cells.
A. Damert, E. Ikeda, W. Risau
1997Biochemical Journal234 citations Open access
Semantic Scholar
Overexpression of vascular endothelial growth factor in the avian embryo induces hypervascularization and increased vascular permeability without alterations of embryonic pattern formation.
I. Flamme, Marie von Reutern, H. Drexler, S. Syed-Ali +1 more
1995Developmental Biology233 citations Open access
Semantic Scholar
VEGF Gene Transfer Reduces Intimal Thickening via Increased Production of Nitric Oxide in Carotid Arteries
Marja Laitinen, I. Zachary, G. Breier, T. Pakkanen +8 more
1997Human Gene Therapy223 citations
Semantic Scholar
Up-regulation of flk-1/vascular endothelial growth factor receptor 2 by its ligand in a cerebral slice culture system.
C. Kremer, G. Breier, W. Risau, K. Plate
1997Cancer Research210 citations
Semantic Scholar
VEGF induces hyperpermeability by a direct action on endothelial cells.
S. Hippenstiel, M. Krüll, A. Ikemann, W. Risau +2 more
1998American Journal of Physiology - Lung cellular and Molecular Physiology204 citations
Semantic Scholar
Hypoxic regulation of vascular endothelial growth factor mRNA stability requires the cooperation of multiple RNA elements.
J. A. Dibbens, D. L. Miller, A. Damert, W. Risau +2 more
1999Molecular Biology of the Cell193 citations Open access
Semantic Scholar
Hypoxia and platelet‐derived growth factor‐BB synergistically upregulate the expression of vascular endothelial growth factor in vascular smooth muscle cells
G. T. Stavri, Ying Hong, I. Zachary, G. Breier +5 more
1995FEBS Letters181 citations
Semantic Scholar
Endothelium‐specific replacement of the connexin43 coding region by a lacZ reporter gene
M. Theis, C. de Wit, T. Schlaeger, D. Eckardt +6 more
2001Genesis180 citations
Semantic Scholar
Development of blood-brain barrier tight junctions in the rat cortex.
U. Kniesel, W. Risau, H. Wolburg
1996Brain research. Developmental brain research172 citations
Semantic Scholar
Role of SCL/Tal-1, GATA, and ets transcription factor binding sites for the regulation of flk-1 expression during murine vascular development.
Andreas Kappel, T. Schlaeger, I. Flamme, S. Orkin +2 more
2000Blood171 citations
Semantic Scholar
Insufficient VEGFA activity in yolk sac endoderm compromises haematopoietic and endothelial differentiation.
A. Damert, L. Miquerol, M. Gertsenstein, W. Risau +1 more
2002Development170 citations
Semantic Scholar
Regulation of endothelial monocyte-activating polypeptide II release by apoptosis.
U. Knies, Heike A. Behrensdorf, Christopher A. Mitchell, Urban Deutsch +3 more
1998Proceedings of the National Academy of Sciences of the United States of America167 citations Open access
Semantic Scholar
Inhibition of proteasome function induces programmed cell death in proliferating endothelial cells
H. Drexler, W. Risau, M. Konerding
2000The FASEB Journal165 citations
Semantic Scholar
Development and differentiation of endothelium.
W. Risau
1998Kidney international. Supplement163 citations Open access
Semantic Scholar
Functional interaction of vascular endothelial-protein-tyrosine phosphatase with the Angiopoietin receptor Tie-2
G. Fachinger, U. Deutsch, W. Risau
1999Oncogene162 citations
Semantic Scholar
The role of vascular endothelial growth factor in blood vessel formation.
Georg Breier, W. Risau
1996Trends in Cell Biology160 citations
Semantic Scholar
A dominant mutant of occludin disrupts tight junction structure and function.
S. Bamforth, U. Kniesel, H. Wolburg, B. Engelhardt +1 more
1999Journal of Cell Science151 citations
Semantic Scholar
Astrocyte mediated modulation of blood-brain barrier permeability does not correlate with a loss of tight junction proteins from the cellular contacts
Stefan Hamm, B. Dehouck, J. Kraus, K. Wolburg-Buchholz +5 more
2004Cell and Tissue Research146 citations Open access
Semantic Scholar
Vascular endothelial growth factor induces VE-cadherin tyrosine phosphorylation in endothelial cells.
S. Esser, M. Lampugnani, M. Corada, Elisabetta Dejana +1 more
1998Journal of Cell Science145 citations
Semantic Scholar
Angiogenesis in Embryos and Ischemic Diseases
G. Breier, A. Damert, K. Plate, W. Risau
1997Thrombosis and Haemostasis145 citations
Semantic Scholar

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