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T. Borner · SciRah

Researcher profile · Semantic Scholar

T. Borner

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T. Borner — researcher profile on SciRah

h-index: 20
Works: 45
Citations: 1,361

Most-cited papers

GDF15 Induces Anorexia through Nausea and Emesis
T. Borner, E. Shaulson, M. Ghidewon, Amanda B Barnett +5 more
2020Cell Metabolism224 citations Open access
Semantic Scholar
GIP Receptor Agonism Attenuates GLP-1 Receptor Agonist–Induced Nausea and Emesis in Preclinical Models
T. Borner, C. Geisler, Samantha M. Fortin, R. Cosgrove +16 more
2021Diabetes184 citations Open access
Semantic Scholar
GABA neurons in the nucleus tractus solitarius express GLP-1 receptors and mediate anorectic effects of liraglutide in rats
Samantha M. Fortin, R. Lipsky, Rinzin Lhamo, Jack Chen +4 more
2020Science Translational Medicine109 citations Open access
Semantic Scholar
GDF15 Induces an Aversive Visceral Malaise State that Drives Anorexia and Weight Loss
T. Borner, H. Wald, M. Ghidewon, B. Zhang +4 more
2020Cell Reports88 citations Open access
Semantic Scholar
GIPR Agonism Inhibits PYY-Induced Nausea-Like Behavior
R. Samms, R. Cosgrove, Brandy M. Snider, E. C. Furber +12 more
2022Diabetes63 citations Open access
Semantic Scholar
The Role of GIP in the Regulation of GLP-1 Satiety and Nausea
M. Hayes, T. Borner, B. D. De Jonghe
2021Diabetes58 citations Open access
Semantic Scholar
Growth differentiation factor 15 (GDF15) and semaglutide inhibit food intake and body weight through largely distinct, additive mechanisms
M. Ghidewon, H. Wald, A. D. McKnight, B. D. De Jonghe +4 more
2022Diabetes, obesity and metabolism48 citations Open access
Semantic Scholar
Glucagon-like peptide-1 in diabetes care: Can glycaemic control be achieved without nausea and vomiting?
T. Borner, Ian C. Tinsley, Robert P. Doyle, Matthew R. Hayes +1 more
2021British Journal of Pharmacology41 citations Open access
Semantic Scholar
Anorexia‐cachexia syndrome in hepatoma tumour‐bearing rats requires the area postrema but not vagal afferents and is paralleled by increased MIC‐1/GDF15
T. Borner, M. Arnold, Johan Ruud, S. Breit +4 more
2016Journal of Cachexia, Sarcopenia and Muscle37 citations Open access
Semantic Scholar
A Vitamin B12 Conjugate of Exendin-4 Improves Glucose Tolerance Without Associated Nausea or Hypophagia in Rodents
Elizabeth G. Mietlicki-Baase, Claudia G. Liberini, Jayme L. Workinger, Ron L. Bonaccorso +11 more
2018Diabetes, obesity and metabolism36 citations Open access
Semantic Scholar
Brainstem GLP‐1 signalling contributes to cancer anorexia‐cachexia syndrome in the rat
T. Borner, Claudia G. Liberini, T. Lutz, T. Riediger
2018Neuropharmacology36 citations Open access
Semantic Scholar
Design and Evaluation of Peptide Dual-Agonists of GLP-1 and NPY2 Receptors for Glucoregulation and Weight Loss with Mitigated Nausea and Emesis
Brandon T. Milliken, Clinton T. Elfers, O. Chepurny, Kylie S. Chichura +7 more
2021Journal of Medicinal Chemistry34 citations Open access
Semantic Scholar
The ghrelin receptor agonist HM01 mimics the neuronal effects of ghrelin in the arcuate nucleus and attenuates anorexia-cachexia syndrome in tumor-bearing rats.
T. Borner, Laura Loi, C. Pietra, C. Giuliano +2 more
2016American Journal of Physiology. Regulatory Integrative and Comparative Physiology34 citations Open access
Semantic Scholar
Corrination of a GLP-1 Receptor Agonist for Glycemic Control without Emesis
T. Borner, Jayme L. Workinger, Ian C. Tinsley, Samantha M. Fortin +12 more
2020Cell Reports33 citations Open access
Semantic Scholar
GIP receptor agonism blocks chemotherapy-induced nausea and vomiting
T. Borner, Benjamin C. Reiner, R. Crist, C. Furst +6 more
2023Molecular Metabolism30 citations Open access
Semantic Scholar
Hypophagia induced by hindbrain serotonin is mediated through central GLP-1 signaling and involves 5-HT2C and 5-HT3 receptor activation
Rosa M. Leon, T. Borner, David J. Reiner, L. Stein +3 more
2019Neuropsychopharmacology28 citations Open access
Semantic Scholar
The satiating hormone amylin enhances neurogenesis in the area postrema of adult rats
Claudia G. Liberini, T. Borner, C. Boyle, T. Lutz
2016Molecular Metabolism28 citations Open access
Semantic Scholar
Single nuclei RNA sequencing of the rat AP and NTS following GDF15 treatment
Benjamin C. Reiner, R. Crist, T. Borner, R. Doyle +2 more
2021Molecular Metabolism25 citations Open access
Semantic Scholar
The anti-emetic actions of GIP receptor agonism.
T. Borner, B. D. De Jonghe, Matthew R. Hayes
2024American Journal of Physiology. Endocrinology and Metabolism21 citations Open access
Semantic Scholar
A second-generation glucagon-like peptide-1 receptor agonist mitigates vomiting and anorexia while retaining glucoregulatory potency in lean diabetic and emetic mammalian models
T. Borner, E. Shaulson, Ian C. Tinsley, L. Stein +4 more
2020Diabetes, obesity and metabolism20 citations Open access
Semantic Scholar
Lipopolysaccharide inhibits ghrelin-excited neurons of the arcuate nucleus and reduces food intake via central nitric oxide signaling.
T. Borner, S. Pinkernell, T. Lutz, T. Riediger
2012Brain, behavior, and immunity20 citations Open access
Semantic Scholar
Human OPRM1 and murine Oprm1 promoter driven viral constructs for genetic access to μ-opioidergic cell types
Gregory J. Salimando, Sébastien Tremblay, Blake A. Kimmey, Jia Li +21 more
2023Nature Communications19 citations Open access
Semantic Scholar
Central mechanisms of emesis: A role for GDF15
T. Borner, A. M. Pataro, B. D. De Jonghe
2024Neurogastroenterology and Motility18 citations
Semantic Scholar
Creation of a Peptide Antagonist of the GFRAL–RET Receptor Complex for the Treatment of GDF15-Induced Malaise
T. Borner, Ian C. Tinsley, Brandon T. Milliken, Sarah A. Doebley +5 more
2023Journal of Medicinal Chemistry16 citations Open access
Semantic Scholar
Hypophagia induced by salmon calcitonin, but not by amylin, is partially driven by malaise and is mediated by CGRP neurons
Lavinia Boccia, T. Borner, M. Ghidewon, Patricia Kulka +6 more
2022Molecular Metabolism16 citations Open access
Semantic Scholar
Hypophagia and body weight loss by tirzepatide are accompanied by fewer GI adverse events compared to semaglutide in preclinical models
T. Borner, A. M. Pataro, Sarah A. Doebley, C. Furst +13 more
2025Science Advances15 citations
Semantic Scholar
Activation of PPG neurons following acute stressors differentially involves hindbrain serotonin in male rats
Rosa M. Leon, T. Borner, L. Stein, Norma A. Urrutia +3 more
2021Neuropharmacology14 citations Open access
Semantic Scholar
Peripherally restricted oxytocin is sufficient to reduce food intake and motivation, while CNS-entry is required for locomotor and taste avoidance effects
Mohammed Asker, Jean-Philippe Krieger, Amber Liles, Ian C. Tinsley +11 more
2022Diabetes, obesity and metabolism12 citations Open access
Semantic Scholar
GPR-160 Receptor Signaling in the Dorsal Vagal Complex of Male Rats Modulates Meal Microstructure and CART-Mediated Hypophagia
Marcos J. Sanchez-Navarro, T. Borner, Benjamin C. Reiner, R. Crist +4 more
2023Nutrients10 citations Open access
Semantic Scholar
Synthesis, Optimization, and Biological Evaluation of Corrinated Conjugates of the GLP-1R Agonist Exendin-4
Ian C. Tinsley, T. Borner, M. Swanson, O. Chepurny +7 more
2021Journal of Medicinal Chemistry10 citations Open access
Semantic Scholar
GLP‐1 at the Metabolic–Cognitive Interface: Reward, Affect, and Memory
Serena X. Gao, Léa Décarie-Spain, Cindy Gu, Giulia Mazzini +2 more
2026Comprehensive Physiology8 citations Open access
Semantic Scholar
GLP-1R biased cAMP agonism maintains glycemic control with reduced malaise and emesis in preclinical mammalian models
Caitlin Baumer-Harrison, Danya Aldaghma, Alex D. White, Sarah V Applebey +15 more
2026Diabetes, obesity and metabolism7 citations Open access
Semantic Scholar
Screening study of anti-emetics to improve GDF15-induced malaise and anorexia: Implications for emesis control
T. Borner, Sarah A. Doebley, C. Furst, A. M. Pataro +6 more
2023Physiology and Behavior6 citations
Semantic Scholar
Novel Insights into the Physiology of Nutrient Sensing and Gut-Brain Communication in Surgical and Experimental Obesity Therapy
L. Frick, M. Hankir, T. Borner, E. Malagola +2 more
2023Obesity Surgery5 citations Open access
Semantic Scholar
Olanzapine Administration Reduces Chemotherapy-Induced Nausea Behavior in Rats
R. Jaime-Lara, T. Borner, Ruby A. Holland, E. Shaulson +2 more
2021Biological Research for Nursing4 citations Open access
Semantic Scholar
Glucagon-like peptide-1 signaling in learning and memory: evidence, mechanisms, and therapeutic implications
Alexander G. Bashaw, Ciorana Roman-Ortiz, Serena X. Gao, L. A. Schier +2 more
2026Biological Psychiatry3 citations Open access
Semantic Scholar
GIPR signaling modulates PYY-induced hypophagia and malaise in rodents
T. Borner, A. M. Pataro, Genevieve R. Curtis, Brandon Alonso +16 more
2026Molecular Metabolism2 citations Open access
Semantic Scholar
Hindbrain octadecaneuropeptide gliotransmission as a therapeutic target for energy balance control without nausea or emesis
C. Geisler, K.S. Chichura, Oleksandr Orativskyi, Jiayin Hu +9 more
2025Science Translational Medicine2 citations Open access
Semantic Scholar
One receptor, two opposite approaches: efficacy and tolerability of GIPR agonism and antagonism in obesity pharmacotherapy.
Serena X. Gao, T. Borner
2026Appetite1 citations Open access
Semantic Scholar
A Dicyanocobinamide Conjugate of the GLP-1R Agonist Exendin-4 Improves Glucose Homeostasis in Tumor-Bearing Rats without Exacerbating Anorexia and Weight Loss.
Nancy Cham, A. M. Pataro, Amber Liles, Grace Choi +10 more
2026Molecular Pharmaceutics0 citations Open access
Semantic Scholar
An Incretin-Dependent Modulation of Periprandial Neutrophilia.
A. Baragetti, L. Da Dalt, A. Parolini, A. Moregola +9 more
2026Diabetes0 citations
Semantic Scholar
Beyond GLP-1: Amylin-Based Pharmacotherapy and the Search for Better-Tolerated Weight-Loss Drugs.
Sophia L. Fischer, T. Borner
2026Pharmacological Research0 citations Open access
Semantic Scholar
Viral Strategies for Targeting and Manipulating Opioidergic Neuronal Populations for Cell Specific Study and Therapeutic Intervention
Gregory J. Salimando, S. Tremblay, T. Borner, M. Hayes +6 more
2022Journal of Pain0 citations Open access
Semantic Scholar
Neuronal mechanisms involved in cancer anorexia‐cachexia syndrome and evaluation of possible therapeutic approaches
T. Borner
20170 citations
Semantic Scholar
LPS inhibits ghrelin-excited neurons and food intake via central nitric oxide signaling
T. Borner, S. Pinkernell, T. Lutz, T. Riediger
20110 citations
Semantic Scholar

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B. D. De Jonghe×30
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M. Hayes×16
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Sarah A. Doebley×9
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R. Doyle×8
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Matthew R. Hayes

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M. Ghidewon — researcher profile on SciRah

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T. Lutz — researcher profile on SciRah

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A. M. Pataro×6

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Ian C. Tinsley — researcher profile on SciRah