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M. Simionescu · SciRah

Researcher profile · Semantic Scholar

M. Simionescu

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M. Simionescu — researcher profile on SciRah

h-index: 50
Works: 232
Citations: 11K

Most-cited papers

Factors Secreted by Mesenchymal Stem Cells and Endothelial Progenitor Cells Have Complementary Effects on Angiogenesis In Vitro
A. Burlacu, G. Grigorescu, A. Rosca, M. Preda +1 more
2013Stem Cells and Development158 citations Open access
Semantic Scholar
MiR-486 and miR-92a Identified in Circulating HDL Discriminate between Stable and Vulnerable Coronary Artery Disease Patients
L. Niculescu, Natalia Simionescu, G. M. Sanda, M. Carnuta +7 more
2015PLoS ONE146 citations Open access
Semantic Scholar
Inflammation in atherosclerosis: a cause or a result of vascular disorders?
I. Manduteanu, M. Simionescu
2012Journal of Cellular and Molecular Medicine142 citations Open access
Semantic Scholar
Short lifespan of syngeneic transplanted MSC is a consequence of in vivo apoptosis and immune cell recruitment in mice
M. Preda, C. Neculachi, I. Fenyo, A. Vacaru +3 more
2021Cell Death and Disease115 citations Open access
Semantic Scholar
Transcriptional Profiling and Functional Analysis of N1/N2 Neutrophils Reveal an Immunomodulatory Effect of S100A9-Blockade on the Pro-Inflammatory N1 Subpopulation
A. Mihaila, L. Ciortan, R. Macarie, M. Vadana +11 more
2021Frontiers in Immunology107 citations Open access
Semantic Scholar
Human Mesenchymal Stromal Cell-Derived Exosomes Promote In Vitro Wound Healing by Modulating the Biological Properties of Skin Keratinocytes and Fibroblasts and Stimulating Angiogenesis
R. Tutuianu, A. Rosca, D. Iacomi, M. Simionescu +1 more
2021International Journal of Molecular Sciences103 citations Open access
Semantic Scholar
Cell-derived microparticles in atherosclerosis: biomarkers and targets for pharmacological modulation?
Morgane Baron, C. Boulanger, B. Staels, A. Tailleux +1 more
2012Journal of Cellular and Molecular Medicine83 citations Open access
Semantic Scholar
Pharmacological inhibition of histone deacetylase reduces NADPH oxidase expression, oxidative stress and the progression of atherosclerotic lesions in hypercholesterolemic apolipoprotein E-deficient mice; potential implications for human atherosclerosis
S. Manea, M. Vlad, I. Fenyo, A. Lazar +4 more
2019Redox Biology73 citations Open access
Semantic Scholar
Epigenetic regulation of vascular NADPH oxidase expression and reactive oxygen species production by histone deacetylase-dependent mechanisms in experimental diabetes
S. Manea, Mihaela-Loredana Antonescu, I. Fenyo, M. Raicu +2 more
2018Redox Biology67 citations Open access
Semantic Scholar
Dysfunctional high-density lipoproteins have distinct composition, diminished anti-inflammatory potential and discriminate acute coronary syndrome from stable coronary artery disease patients
M. Carnuta, C. Stancu, L. Toma, G. M. Sanda +8 more
2017Scientific Reports61 citations Open access
Semantic Scholar
Cross talk between smooth muscle cells and monocytes/activated monocytes via CX3CL1/CX3CR1 axis augments expression of pro-atherogenic molecules.
E. Butoi, Ana-Maria Gan, I. Manduteanu, D. Stan +5 more
2011Biochimica et Biophysica Acta61 citations Open access
Semantic Scholar
Human monocytes and macrophages express NADPH oxidase 5; a potential source of reactive oxygen species in atherosclerosis.
A. Manea, S. Manea, Ana-Maria Gan, A. Constantin +4 more
2015Biochemical and Biophysical Research Communications - BBRC60 citations
Semantic Scholar
Foam cell-derived 4-hydroxynonenal induces endothelial cell senescence in a TXNIP-dependent manner
Y. Riahi, N. Kaiser, G. Cohen, Ihab Abd-Elrahman +12 more
2015Journal of Cellular and Molecular Medicine59 citations Open access
Semantic Scholar
Remote Transplantation of Mesenchymal Stem Cells Protects the Heart Against Ischemia‐Reperfusion Injury
M. Preda, Torunn Rønningen, A. Burlacu, M. Simionescu +2 more
2014Stem Cells58 citations Open access
Semantic Scholar
Osteoblast ontogeny and implications for bone pathology: an overview
I. Titorencu, V. Prună, V. Jinga, M. Simionescu
2013Cell and Tissue Research54 citations
Semantic Scholar
VCAM-1 directed target-sensitive liposomes carrying CCR2 antagonists bind to activated endothelium and reduce adhesion and transmigration of monocytes.
Manuela Calin, D. Stan, Martin Schlesinger, Viorel Simion +11 more
2015European journal of pharmaceutics and biopharmaceutics53 citations Open access
Semantic Scholar
Inflammatory effects of resistin on human smooth muscle cells: up-regulation of fractalkine and its receptor, CX3CR1 expression by TLR4 and Gi-protein pathways
Ana-Maria Gan, E. Butoi, A. Manea, Viorel Simion +5 more
2012Cell and Tissue Research51 citations
Semantic Scholar
Activated Histone Acetyltransferase p300/CBP-Related Signalling Pathways Mediate Up-Regulation of NADPH Oxidase, Inflammation, and Fibrosis in Diabetic Kidney
A. Lazar, M. Vlad, A. Manea, M. Simionescu +1 more
2021Antioxidants46 citations Open access
Semantic Scholar
A novel pro-inflammatory mechanism of action of resistin in human endothelial cells: up-regulation of SOCS3 expression through STAT3 activation.
M. Pirvulescu, I. Manduteanu, Ana-Maria Gan, D. Stan +4 more
2012Biochemical and Biophysical Research Communications - BBRC46 citations
Semantic Scholar
Histone Acetyltransferase-Dependent Pathways Mediate Upregulation of NADPH Oxidase 5 in Human Macrophages under Inflammatory Conditions: A Potential Mechanism of Reactive Oxygen Species Overproduction in Atherosclerosis
M. Vlad, S. Manea, A. Lazar, M. Raicu +3 more
2019Oxidative Medicine and Cellular Longevity44 citations Open access
Semantic Scholar
Nox enzymes and oxidative stress in atherosclerosis.
A. Manea, M. Simionescu
2012Frontiers in Bioscience43 citations Open access
Semantic Scholar
P-selectin targeted RAGE-shRNA lipoplexes alleviate atherosclerosis-associated inflammation.
Cristina Ana Mocanu, E. Fuior, Geanina Voicu, Daniela Rebleanu +7 more
2021Journal of Controlled Release42 citations Open access
Semantic Scholar
Hyperglycemia Determines Increased Specific MicroRNAs Levels in Sera and HDL of Acute Coronary Syndrome Patients and Stimulates MicroRNAs Production in Human Macrophages
Natalia Simionescu, L. Niculescu, M. Carnuta, G. M. Sanda +7 more
2016PLoS ONE40 citations Open access
Semantic Scholar
High-glucose-increased expression and activation of NADPH oxidase in human vascular smooth muscle cells is mediated by 4-hydroxynonenal-activated PPARα and PPARβ/δ
A. Manea, S. Manea, A. Todirita, Irina Cristina Albulescu +3 more
2015Cell and Tissue Research39 citations
Semantic Scholar
Synergic effects of VEGF‐A and SDF‐1 on the angiogenic properties of endothelial progenitor cells
Gabriela Odent (Grigorescu), A. Rosca, M. Preda, R. Tutuianu +2 more
2017Journal of Tissue Engineering and Regenerative Medicine36 citations Open access
Semantic Scholar
A novel platform for drug testing: Biomimetic three-dimensional hyaluronic acid-based scaffold seeded with human hepatocarcinoma cells.
M. Turtoi, Maria Anghelache, Sanda Bucatariu, M. Deleanu +6 more
2021International Journal of Biological Macromolecules35 citations Open access
Semantic Scholar
Alarmins in chronic noncommunicable diseases: Atherosclerosis, diabetes and cancer.
R. M. Boteanu, V. Șuică, E. Uyy, L. Ivan +4 more
2017Journal of Proteomics34 citations
Semantic Scholar
Conjugation of curcumin‐loaded lipid nanoemulsions with cell‐penetrating peptides increases their cellular uptake and enhances the anti‐inflammatory effects in endothelial cells
Viorel Simion, D. Stan, C. A. Constantinescu, M. Deleanu +8 more
2016The Journal of pharmacy and pharmacology34 citations
Semantic Scholar
P-Selectin Targeted Dexamethasone-Loaded Lipid Nanoemulsions: A Novel Therapy to Reduce Vascular Inflammation
Viorel Simion, C. A. Constantinescu, D. Stan, M. Deleanu +5 more
2016Mediators of Inflammation32 citations Open access
Semantic Scholar
Extracellular Vesicles: Versatile Nanomediators, Potential Biomarkers and Therapeutic Agents in Atherosclerosis and COVID-19-Related Thrombosis
A. Georgescu, M. Simionescu
2021International Journal of Molecular Sciences31 citations Open access
Semantic Scholar
Functional Role of VCAM-1 Targeted Flavonoid-Loaded Lipid Nanoemulsions in Reducing Endothelium Inflammation
E. Fuior, M. Deleanu, C. A. Constantinescu, Daniela Rebleanu +3 more
2019Pharmaceutics30 citations Open access
Semantic Scholar
The expression of MMP‐1 and MMP‐9 is up‐regulated by smooth muscle cells after their cross‐talk with macrophages in high glucose conditions
R. Macarie, M. Vadana, L. Ciortan, M. Tucureanu +5 more
2018Journal of Cellular and Molecular Medicine28 citations Open access
Semantic Scholar
Targeted delivery of CCR2 antagonist to activated pulmonary endothelium prevents metastasis
Marko Roblek, Manuela Calin, Martin Schlesinger, D. Stan +4 more
2015Journal of Controlled Release28 citations Open access
Semantic Scholar
Morphology of Atherosclerotic Lesions
M. Simionescu, A. Sima
201228 citations
Semantic Scholar
Catalyzing Transcriptomics Research in Cardiovascular Disease: The CardioRNA COST Action CA17129
C. Gomes, B. Ágg, Andrejaana Andova, S. Arslan +51 more
2019Non-Coding RNA24 citations Open access
Semantic Scholar
Targeted Transfection Using PEGylated Cationic Liposomes Directed Towards P-Selectin Increases siRNA Delivery into Activated Endothelial Cells
C. A. Constantinescu, E. Fuior, Daniela Rebleanu, M. Deleanu +6 more
2019Pharmaceutics24 citations Open access
Semantic Scholar
Aortic valve disease in diabetes: Molecular mechanisms and novel therapies
I. Manduteanu, D. Simionescu, Agneta Simionescu, M. Simionescu
2021Journal of Cellular and Molecular Medicine23 citations Open access
Semantic Scholar
Parathyroid Hormone Induces Human Valvular Endothelial Cells Dysfunction That Impacts the Osteogenic Phenotype of Valvular Interstitial Cells
M. Vadana, S. Cecoltan, L. Ciortan, R. Macarie +7 more
2022International Journal of Molecular Sciences22 citations Open access
Semantic Scholar
CO2 laser increases the regenerative capacity of human adipose-derived stem cells by a mechanism involving the redox state and enhanced secretion of pro-angiogenic molecules
A. Constantin, M. Dumitrescu, M. Mihai, D. Jianu +1 more
2016Lasers in Medical Science22 citations
Semantic Scholar
Evaluation of VCAM-1 Targeted Naringenin/Indocyanine Green-Loaded Lipid Nanoemulsions as Theranostic Nanoplatforms in Inflammation
E. Fuior, C. Mocanu, M. Deleanu, Geanina Voicu +4 more
2020Pharmaceutics21 citations Open access
Semantic Scholar
Hyperlipidemia-induced hepatic and small intestine ER stress and decreased paraoxonase 1 expression and activity is associated with HDL dysfunction in Syrian hamsters.
C. Stancu, M. Carnuta, G. M. Sanda, L. Toma +5 more
2015Molecular Nutrition & Food Research21 citations
Semantic Scholar
Dual Stem Cell Therapy Improves the Myocardial Recovery Post-Infarction through Reciprocal Modulation of Cell Functions
S. Popescu, M. Preda, C. Marinescu, M. Simionescu +1 more
2021International Journal of Molecular Sciences19 citations Open access
Semantic Scholar
Mesenchymal stromal cell‐derived factors promote the colonization of collagen 3D scaffolds with human skin cells
R. Tutuianu, A. Rosca, M. A. Albu Kaya, V. Prună +4 more
2020Journal of Cellular and Molecular Medicine19 citations Open access
Semantic Scholar
Increased miR-142 Levels in Plasma and Atherosclerotic Plaques from Peripheral Artery Disease Patients with Post-Surgery Cardiovascular Events
Teodora Barbalata, O. Moraru, C. Stancu, Y. Devaux +3 more
2020International Journal of Molecular Sciences19 citations Open access
Semantic Scholar
Detection of Vascular Reactive Oxygen Species in Experimental Atherosclerosis by High-Resolution Near-Infrared Fluorescence Imaging Using VCAM-1-Targeted Liposomes Entrapping a Fluorogenic Redox-Sensitive Probe
S. Manea, M. Vlad, Daniela Rebleanu, A. Lazar +4 more
2021Oxidative Medicine and Cellular Longevity17 citations Open access
Semantic Scholar
Testosterone stimulates proliferation and preserves stemness of human adult mesenchymal stem cells and endothelial progenitor cells.
M. C. Corotchi, M. Popa, M. Simionescu
2016Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie17 citations
Semantic Scholar
Thyroid hormones upregulate apolipoprotein E gene expression in astrocytes.
Corina Roman, E. Fuior, V. Trusca, D. Kardassis +2 more
2015Biochemical and Biophysical Research Communications - BBRC16 citations
Semantic Scholar
Evidence of mesenchymal stromal cell adaptation to local microenvironment following subcutaneous transplantation
M. Preda, Ana-Mihaela Lupan, C. Neculachi, L. Leti +6 more
2020Journal of Cellular and Molecular Medicine15 citations Open access
Semantic Scholar
The Mechanism of Bisphenol A Atherogenicity Involves Apolipoprotein A-I Downregulation through NF-κB Activation
V. Trusca, M. Dumitrescu, I. Fenyo, I. Tudorache +2 more
2019International Journal of Molecular Sciences15 citations Open access
Semantic Scholar
Differential action of glucocorticoids on apolipoprotein E gene expression in macrophages and hepatocytes
V. Trusca, E. Fuior, I. Fenyo, D. Kardassis +2 more
2017PLoS ONE15 citations Open access
Semantic Scholar

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