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Luke Isbel · SciRah

Researcher profile · Semantic Scholar

Luke Isbel

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Luke Isbel — researcher profile on SciRah

h-index: 15
Works: 26
Citations: 958

Most-cited papers

Mechanisms of OCT4-SOX2 motif readout on nucleosomes
A. Michael, R. S. Grand, Luke Isbel, S. Cavadini +11 more
2020Science206 citations
Semantic Scholar
Generating specificity in genome regulation through transcription factor sensitivity to chromatin
Luke Isbel, R. S. Grand, D. Schübeler
2022Nature reviews genetics124 citations
Semantic Scholar
Cooperation between bHLH transcription factors and histones for DNA access
A. Michael, Lisa Stoos, P. Crosby, Nikolas Eggers +23 more
2023Nature101 citations Open access
Semantic Scholar
An ENU mutagenesis screen identifies novel and known genes involved in epigenetic processes in the mouse
L. Daxinger, S. Harten, Harald Oey, T. Epp +15 more
2013Genome Biology84 citations Open access
Semantic Scholar
BANP opens chromatin and activates CpG-island-regulated genes
R. S. Grand, Lukas Burger, Cathrin Gräwe, A. Michael +11 more
2021Nature79 citations
Semantic Scholar
Genetic and epigenetic variation among inbred mouse littermates: identification of inter-individual differentially methylated regions
Harald Oey, Luke Isbel, Peter F. Hickey, B. Ebaid +1 more
2015Epigenetics & Chromatin53 citations Open access
Semantic Scholar
CG dinucleotides enhance promoter activity independent of DNA methylation
Dominik Hartl, A. Krebs, R. S. Grand, T. Baubec +4 more
2019Genome Research52 citations Open access
Semantic Scholar
Readout of histone methylation by Trim24 locally restricts chromatin opening by p53
Luke Isbel, M. Iskar, S. Durdu, Joscha Weiss +7 more
2022bioRxiv41 citations Open access
Semantic Scholar
Endogenous retroviruses in mammals: An emerging picture of how ERVs modify expression of adjacent genes
Luke Isbel, E. Whitelaw
2012Bioessays34 citations
Semantic Scholar
Wiz binds active promoters and CTCF-binding sites and is required for normal behaviour in the mouse
Luke Isbel, Lexie Prokopuk, Hao-Yu Wu, L. Daxinger +5 more
2016eLife28 citations Open access
Semantic Scholar
Trim33 Binds and Silences a Class of Young Endogenous Retroviruses in the Mouse Testis; a Novel Component of the Arms Race between Retrotransposons and the Host Genome
Luke Isbel, R. Srivastava, Harald Oey, A. Spurling +3 more
2015PLoS Genetics28 citations Open access
Semantic Scholar
Accurate PROTAC-targeted degradation prediction with DegradeMaster
Jie Liu, M. Roy, Luke Isbel, Fu-Yi Li
2025bioRxiv26 citations Open access
Semantic Scholar
ZFP462 safeguards neural lineage specification by targeting G9A/GLP-mediated heterochromatin to silence enhancers
R. Yelagandula, Karin Stecher, M. Novatchkova, Luca Michetti +11 more
2023Nature Cell Biology26 citations Open access
Semantic Scholar
Hypomethylation of ERVs in the sperm of mice haploinsufficient for the histone methyltransferase Setdb1 correlates with a paternal effect on phenotype
L. Daxinger, Harald Oey, Luke Isbel, Nadia C. Whitelaw +4 more
2016Scientific Reports24 citations Open access
Semantic Scholar
The recently identified modifier of murine metastable epialleles, Rearranged L-Myc Fusion, is involved in maintaining epigenetic marks at CpG island shores and enhancers
S. Harten, Harald Oey, Lauren M. Bourke, V. Bharti +6 more
2015BMC Biology19 citations Open access
Semantic Scholar
Social approach, anxiety, and altered tryptophan hydroxylase 2 activity in juvenile BALB/c and C57BL/6J mice
Adrian M. Russo, Adam J. Lawther, Benjamin M. Prior, Luke Isbel +7 more
2019Behavioural Brain Research15 citations Open access
Semantic Scholar
Chromatin-dependent motif syntax defines differentiation trajectories
S. Durdu, M. Iskar, Luke Isbel, Leslie Hoerner +5 more
2024bioRxiv8 citations
Semantic Scholar
Nucleosomes specify co-factor access to p53.
Deyasini Chakraborty, C. Sandate, Luke Isbel, G. Kempf +10 more
2025Molecules and Cells5 citations Open access
Semantic Scholar
Commentary: Far-reaching hypothesis or a step too far: the inheritance of acquired characteristics.
Luke Isbel, E. Whitelaw
2015International Journal of Epidemiology5 citations
Semantic Scholar
ZFP462 targets heterochromatin to transposon-derived enhancers restricting transcription factor binding and expression of lineage-specifying genes
R. Yelagandula, Karin Stecher, M. Novatchkova, Luca Michetti +11 more
2021bioRxiv1 citations Open access
Semantic Scholar
Non-mendelian Inheritance in Mammals Is Highly Constrained.
Luke Isbel, D. Schübeler
2018Cell1 citations Open access
Semantic Scholar
Faculty Opinions recommendation of Notes on the role of dynamic DNA methylation in mammalian development.
E. Whitelaw, Luke Isbel
20161 citations
Semantic Scholar
The Identification of Mammalian Proteins Involved in Epigenetics
Luke Isbel, H. Oey, E. Whitelaw
20151 citations
Semantic Scholar
DesignMaster: a multi-conditional diffusion framework for rational PROTAC design
Binze Shi, Jie Liu, Tong Pan, Yi Hao +5 more
2026bioRxiv0 citations Open access
Semantic Scholar
Faculty of 1000 evaluation for Intrinsic DNA binding properties demonstrated for lineage-specifying basic helix-loop-helix transcription factors.
D. Schübeler, Luke Isbel
20180 citations
Semantic Scholar
Author response: Wiz binds active promoters and CTCF-binding sites and is required for normal behaviour in the mouse
Luke Isbel, Lexie Prokopuk, Hao-Yu Wu, L. Daxinger +5 more
20160 citations Open access
Semantic Scholar

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