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Ke Zhang · SciRah

Researcher profile · Semantic Scholar

Ke Zhang

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Ke Zhang — researcher profile on SciRah

h-index: 20
Works: 46
Citations: 1,300

Most-cited papers

A chimeric human-cat fusion protein blocks cat-induced allergy
Dao-Cheng Zhu, C. Kepley, Ke Zhang, T. Terada +2 more
2005Nature Medicine186 citations
Semantic Scholar
A novel human immunoglobulin Fcγ–Fcɛ bifunctional fusion protein inhibits FcɛRI-mediated degranulation
Dao-Cheng Zhu, C. Kepley, Min Zhang, Ke Zhang +1 more
2002Nature Medicine141 citations Open access
Semantic Scholar
Co-aggregation of FcγRII with FcϵRI on Human Mast Cells Inhibits Antigen-induced Secretion and Involves SHIP-Grb2-Dok Complexes*
C. Kepley, Sharven Taghavi, G. Mackay, Dao-Cheng Zhu +7 more
2004Journal of Biological Chemistry99 citations Open access
Semantic Scholar
Human Activation-Induced Cytidine Deaminase Is Induced by IL-4 and Negatively Regulated by CD45: Implication of CD45 as a Janus Kinase Phosphatase in Antibody Diversification 1
Cheng-Ji Zhou, A. Saxon, Ke Zhang
2003Journal of Immunology92 citations Open access
Semantic Scholar
A novel human immunoglobulin Fc gamma Fc epsilon bifunctional fusion protein inhibits Fc epsilon RI-mediated degranulation.
Dao-Cheng Zhu, C. Kepley, Min Zhang, Ke Zhang +1 more
2002Nature Medicine80 citations
Semantic Scholar
Direct evidence that gamma 1 and gamma 3 switching in human B cells is interleukin-10 dependent.
S. Fujieda, A. Saxon, Ke Zhang
1996Molecular Immunology63 citations
Semantic Scholar
Inhibition of allergen-specific IgE reactivity by a human Ig Fcγ-Fcε bifunctional fusion protein
Ke Zhang, C. Kepley, T. Terada, Dao-Cheng Zhu +2 more
200453 citations Open access
Semantic Scholar
CD45 Controls Interleukin-4-mediated IgE Class Switch Recombination in Human B Cells through Its Function as a Janus Kinase Phosphatase*
Takechiyo Yamada, Dao-Cheng Zhu, A. Saxon, Ke Zhang
2002Journal of Biological Chemistry49 citations Open access
Semantic Scholar
Complex alternative RNA splicing of epsilon-immunoglobulin transcripts produces mRNAs encoding four potential secreted protein isoforms.
Ke Zhang, E. Max, H. Cheah, A. Saxon
1994Journal of Biological Chemistry47 citations Open access
Semantic Scholar
B lymphocyte stimulator activates p38 mitogen-activated protein kinase in human Ig class switch recombination.
Takechiyo Yamada, Ke Zhang, A. Yamada, Dao-Cheng Zhu +1 more
2005American Journal of Respiratory Cell and Molecular Biology44 citations
Semantic Scholar
A chimeric human-cat Fcgamma-Fel d1 fusion protein inhibits systemic, pulmonary, and cutaneous allergic reactivity to intratracheal challenge in mice sensitized to Fel d1, the major cat allergen.
T. Terada, Ke Zhang, J. Belperio, V. Londhe +1 more
2006Clinical Immunology38 citations
Semantic Scholar
Proteases from Schistosoma mansoni cercariae cleave IgE at solvent exposed interdomain regions.
Akhmed Aslam, P. M. Quinn, R. Mcintosh, Jian-Guo Shi +8 more
2008Molecular Immunology37 citations
Semantic Scholar
Accessibility control and machinery of immunoglobulin class switch recombination
Ke Zhang
2003Journal of Leukocyte Biology37 citations
Semantic Scholar
"Accentuate the negative, eliminate the positive": engineering allergy therapeutics to block allergic reactivity through negative signaling.
A. Saxon, C. Kepley, Ke Zhang
2008Journal of Allergy and Clinical Immunology31 citations Open access
Semantic Scholar
Co-aggregation of FcgammaRII with FcepsilonRI on human mast cells inhibits antigen-induced secretion and involves SHIP-Grb2-Dok complexes.
C. Kepley, Sharven Taghavi, Graham A. Mackay, Dao-Cheng Zhu +7 more
2004Journal of Biological Chemistry31 citations
Semantic Scholar
Expression of Novel Secreted Isoforms of Human Immunoglobulin E Proteins (*)
J. Lyczak, Ke Zhang, A. Saxon, S. Morrison
1996Journal of Biological Chemistry31 citations Open access
Semantic Scholar
Genetically engineered negative signaling molecules in the immunomodulation of allergic diseases
A. Saxon, Dao-Cheng Zhu, Ke Zhang, L. Allen +1 more
2004Current Opinion in Allergy and Clinical Immunology28 citations
Semantic Scholar
CD40-mediated p38 mitogen-activated protein kinase activation is required for immunoglobulin class switch recombination to IgE.
Ke Zhang, Ling Zhang, Dao-Cheng Zhu, David Bae +2 more
2002Journal of Allergy and Clinical Immunology28 citations Open access
Semantic Scholar
Inhibition of allergen-specific IgE reactivity by a human Ig Fcgamma-Fcepsilon bifunctional fusion protein.
Ke Zhang, C. Kepley, T. Terada, Dao-Cheng Zhu +2 more
2004Journal of Allergy and Clinical Immunology27 citations
Semantic Scholar
Modifications to an Fcγ-Fcɛ fusion protein alter its effectiveness in the inhibition of FcɛRI-mediated functions
L. Allen, C. Kepley, A. Saxon, Ke Zhang
200725 citations Open access
Semantic Scholar
FcεRI–FcγRII Coaggregation inhibits IL-16 production from human langerhans-like dendritic cells
C. Kepley, Ke Zhang, Dao-Cheng Zhu, A. Saxon
200319 citations
Semantic Scholar
Inhibition of Interleukin-4-induced Class Switch Recombination by a Human Immunoglobulin Fcγ-Fcϵ Chimeric Protein*
Takechiyo Yamada, Dao-Cheng Zhu, Ke Zhang, A. Saxon
2003Journal of Biological Chemistry16 citations Open access
Semantic Scholar
Association of Ig/BCL6 translocations with germinal center B lymphocytes in human lymphoid tissues: implications for malignant transformation.
Xu-Wei Yang, Koutetsu Lee, J. Said, Xun Gong +1 more
2006Blood14 citations Open access
Semantic Scholar
Chimeric Human Fcγ-Allergen Fusion Proteins in the Prevention of Allergy
Ke Zhang, Dao-Cheng Zhu, C. Kepley, T. Terada +1 more
200713 citations Open access
Semantic Scholar
IgE-Mediated Allergen Gene Vaccine Platform Targeting Human Antigen Presenting Cells Via High Affinity IgE Receptor
A. Behnecke, Wei Li, Ling Chen, A. Saxon +1 more
2009Journal of Allergy and Clinical Immunology10 citations Open access
Semantic Scholar
Modifications to an Fcgamma-Fcvarepsilon fusion protein alter its effectiveness in the inhibition of FcvarepsilonRI-mediated functions.
L. Allen, C. Kepley, A. Saxon, Ke Zhang
2007Journal of Allergy and Clinical Immunology9 citations
Semantic Scholar
Efficiency of Iϵ promoter‐directed switch recombination in GFP expression‐based switch constructs works synergistically with other promoter and/or enhancer elements but is not tightlylinked to the strength of transcription
Ke Zhang, Ling Zhang, Takechiyo Yamada, Michael Vu +2 more
2002European Journal of Immunology9 citations Open access
Semantic Scholar
Inhibition of interleukin-4-induced class switch recombination by a human immunoglobulin Fc gamma-Fc epsilon chimeric protein.
Takechiyo Yamada, Dao-Cheng Zhu, Ke Zhang, A. Saxon
2003Journal of Biological Chemistry8 citations
Semantic Scholar
Blocking allergic reaction through targeting surface-bound IgE with low affinity anti-IgE antibodies
Ke Zhang, Jeffrey Liu, T. Trương, Elyssa Zukin +2 more
2017Journal of Immunology7 citations Open access
Semantic Scholar
FcepsilonRI-FcgammaRII coaggregation inhibits IL-16 production from human Langerhans-like dendritic cells.
C. Kepley, Ke Zhang, Dao-Cheng Zhu, A. Saxon
2003Clinical Immunology7 citations
Semantic Scholar
Chimeric human fcgamma-allergen fusion proteins in the prevention of allergy.
Ke Zhang, Dao-Cheng Zhu, C. Kepley, T. Terada +1 more
2007Immunology and allergy clinics of North America6 citations
Semantic Scholar
The Role of Diesel Exhaust in the Allergic Antibody Response of the Human Airway
A. Saxon, Ke Zhang, H. Takenaka, A. Casillas +1 more
19965 citations
Semantic Scholar
Inhibition of Allergic Reactivity through Targeting FcεRI-Bound IgE with Humanized Low-Affinity Antibodies
Ke Zhang, M. Elias, Hong Zhang, Jeffrey Liu +6 more
2019Journal of Immunology4 citations Open access
Semantic Scholar
Recent advances in the use of genetically engineered negative signaling molecules to treat allergic diseases.
A. Saxon, Dao-Cheng Zhu, Ke Zhang, Lisa A. Chan +1 more
2006Arbeiten aus dem Paul-Ehrlich-Institut (Bundesamt fur Sera und Impfstoffe) zu Frankfurt a.M2 citations
Semantic Scholar
Kif5b Modulates Processing and Secretion of von Willebrand Factor in Endothelial Cells and Mice
Yuyu Luo, Yue Zhuo, Ke Zhang, Xing-De Liu +2 more
20181 citations Open access
Semantic Scholar
A novel multi-potential dendritic cell targeted gene vaccination platform; application to food allergy and beyond.
Ke Zhang, A. Behnecke, Wei Li, A. Saxon
2009Arbeiten aus dem Paul-Ehrlich-Institut (Bundesinstitut fur Impfstoffe und biomedizinische Arzneimittel) Langen/Hessen1 citations
Semantic Scholar
Development of an IgE-based Allergen Gene Vaccine for Severe Food Allergy
A. Behnecke, L. Chen, A. Saxon, Ke Zhang
20081 citations
Semantic Scholar
Cd40 presents a unique isotype specific t cell independent signal for human b cell il 4 induced ige production
Ke Zhang, E. Clark, A. Saxon
19911 citations
Semantic Scholar
THERAPEUTIC ANTI-IGE ANTIBODIES AND METHODS AND COMPOSITIONS THEREOF
A. Saxon, Ke Zhang
20180 citations
Semantic Scholar
Prevention and Treatment of Poly-Lysine Modified Arah2 DNA Vaccine On Arah2 Protein Induced Allergy
Wei Li, Y. Niu, Zhuo-Zhen Zhang, A. Saxon +1 more
20130 citations Open access
Semantic Scholar
Rapid Publication Vasoactive Intestinal Peptide Induces S a / S m Switch Circular DNA in Human B Cells
S. Fujieda, J. Waschek, Ke Zhang, A. Saxon
20130 citations
Semantic Scholar
Iconographies supplémentaires de l'article : CD40-mediated p38 mitogen-activated protein kinase activation is required for immunoglobulin class switch recombination to IgE
Ke Zhang, Ling Zhang, Dao-Cheng Zhu, David Bae +2 more
20110 citations
Semantic Scholar
Dose Dependent Induction of Allergic Tolerance to Peanut by Cutaneous Pre-Treatment with Peanut
Wei Li, A. Behnecke, A. Saxon, Ke Zhang
20090 citations
Semantic Scholar
147 キメラ抗体を用いた新しい免疫療法 : マウス喘息モデルを用いての検討
哲也寺田, Ke Zhang, J. Belperio, Vedang Londe +1 more
20040 citations
Semantic Scholar
The novel human IgE epsilon heavy chain, epsilon tailpiece, is present in plasma as part of a covalent complex: [Mol. Immunol. (2000) 37(5) 241–252]
Lisa A. Chan, J. Lyczak, Ke Zhang, S. Morrison +1 more
20010 citations Open access
Semantic Scholar
254 Trans-splicing of Ig heavy chain RNA transcripts in human B cells
S. Fujieda, Ke Zhang, Y. Q. Lin, A. Saxon
19960 citations
Semantic Scholar

Frequent co-authors

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A. Saxon×38
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A. Saxon — researcher profile on SciRah
Dao-Cheng Zhu×19
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Dao-Cheng Zhu — researcher profile on SciRah
C. Kepley×17
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C. Kepley — researcher profile on SciRah
T. Terada×6
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T. Terada — researcher profile on SciRah

Takechiyo Yamada

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Takechiyo Yamada — researcher profile on SciRah

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A. Saxon — researcher profile on SciRah

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A. Behnecke — researcher profile on SciRah

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S. Morrison — researcher profile on SciRah

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L. Allen — researcher profile on SciRah

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Ling Zhang — researcher profile on SciRah

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Wei Li — researcher profile on SciRah

Min Zhang×2