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I. Laponogov · SciRah

Researcher profile · Semantic Scholar

I. Laponogov

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I. Laponogov — researcher profile on SciRah

h-index: 19
Works: 81
Citations: 1,274

Most-cited papers

Structural insight into the quinolone–DNA cleavage complex of type IIA topoisomerases
I. Laponogov, M. Sohi, D. Veselkov, Xiao-Hui Pan +5 more
2009Nature Structural &Molecular Biology296 citations
Semantic Scholar
Structural Basis of Gate-DNA Breakage and Resealing by Type II Topoisomerases
I. Laponogov, Xiao-Hui Pan, D. Veselkov, K. McAuley +2 more
2010PLoS ONE174 citations Open access
Semantic Scholar
Auto-deconvolution and molecular networking of gas chromatography-mass spectrometry data
A. Aksenov, I. Laponogov, Zheng Zhang, S. Doran +66 more
2020Nature Biotechnology145 citations Open access
Semantic Scholar
HyperFoods: Machine intelligent mapping of cancer-beating molecules in foods
K. Veselkov, Guadalupe Gonzalez, Shahad Aljifri, Dieter Galea +4 more
2019Scientific Reports66 citations Open access
Semantic Scholar
ChemDistiller: an engine for metabolite annotation in mass spectrometry
I. Laponogov, Noureddin M. Sadawi, Dieter Galea, R. Mirnezami +1 more
2018Bioinform.52 citations Open access
Semantic Scholar
Interceptor effect of C60 fullerene on the in vitro action of aromatic drug molecules
G. Skamrova, I. Laponogov, A. Buchelnikov, Y. Shckorbatov +4 more
2014European Biophysics Journal45 citations Open access
Semantic Scholar
BASIS: High-performance bioinformatics platform for processing of large-scale mass spectrometry imaging data in chemically augmented histology
K. Veselkov, J. Sleeman, E. Claude, J. Vissers +9 more
2018Scientific Reports44 citations Open access
Semantic Scholar
Supplementary materials for Structure of an ‘ open ’ clamp type II topoisomerase-DNA complex provides a mechanism for DNA capture and transport
I. Laponogov, D. Veselkov, I. Crevel, Xiao-Hui Pan +2 more
201341 citations
Semantic Scholar
Breakage-Reunion Domain of Streptococcus pneumoniae Topoisomerase IV: Crystal Structure of a Gram-Positive Quinolone Target
I. Laponogov, D. Veselkov, M. Sohi, Xiao-Hui Pan +5 more
2007PLoS ONE32 citations Open access
Semantic Scholar
Structure of a quinolone-stabilized cleavage complex of topoisomerase IV from Klebsiella pneumoniae and comparison with a related Streptococcus pneumoniae complex
D. Veselkov, I. Laponogov, Xiao-Hui Pan, J. Selvarajah +6 more
2016Acta Crystallographica Section D: Structural Biology31 citations Open access
Semantic Scholar
Virus-induced Volatile Organic Compounds are Detectable in Exhaled Breath During Pulmonary Infection.
Faisal Kamal, Sacheen Kumar, M. Edwards, K. Veselkov +14 more
2021American Journal of Respiratory and Critical Care Medicine30 citations Open access
Semantic Scholar
Network machine learning maps phytochemically rich “Hyperfoods” to fight COVID-19
I. Laponogov, Guadalupe Gonzalez, Madelen Shepherd, Ahad Qureshi +7 more
2020Human Genomics28 citations Open access
Semantic Scholar
Exploring the active site of the Streptococcus pneumoniae topoisomerase IV–DNA cleavage complex with novel 7,8-bridged fluoroquinolones
I. Laponogov, Xiao-Hui Pan, D. Veselkov, R. Cirz +4 more
2016Open Biology28 citations Open access
Semantic Scholar
Trapping of the transport-segment DNA by the ATPase domains of a type II topoisomerase
I. Laponogov, Xiao-Hui Pan, D. Veselkov, Galyna B. Skamrova +3 more
2018Nature Communications27 citations Open access
Semantic Scholar
Diagnostic performance of a non-invasive breath test for colorectal cancer: COBRA1 study.
G. Woodfield, I. Belluomo, I. Laponogov, K. Veselkov +15 more
2022Gastroenterology26 citations Open access
Semantic Scholar
Correction: Structural Basis of Gate-DNA Breakage and Resealing by Type II Topoisomerases
I. Laponogov, Xiao-Hui Pan, D. Veselkov, K. McAuley +2 more
2010PLoS ONE26 citations Open access
Semantic Scholar
Structure of an ‘open’ clamp type II topoisomerase-DNA complex provides a mechanism for DNA capture and transport
I. Laponogov, D. Veselkov, Isabelle M.-T. Crevel, Xiao-Hui Pan +2 more
2013Nucleic Acids Research25 citations Open access
Semantic Scholar
Exploiting and assessing multi-source data for supervised biomedical named entity recognition
Dieter Galea, I. Laponogov, K. Veselkov
2018Bioinform.22 citations Open access
Semantic Scholar
Smart CAR-T Nanosymbionts: archetypes and proto-models
J. Baena, J. S. Victoria, Alejandro Toro-Pedroza, C. Aragón +13 more
2025Frontiers in Immunology21 citations Open access
Semantic Scholar
The Helicobacter pylori AI-clinician harnesses artificial intelligence to personalise H. pylori treatment recommendations
Kyle Higgins, O. Nyssen, Joshua Southern, I. Laponogov +32 more
2025Nature Communications21 citations Open access
Semantic Scholar
Predicting anticancer hyperfoods with graph convolutional networks
Guadalupe Gonzalez, Shunwang Gong, I. Laponogov, M. Bronstein +1 more
2021Human Genomics18 citations Open access
Semantic Scholar
Alzheimer’s disease: using gene/protein network machine learning for molecule discovery in olive oil
Luis Rita, Natalie R. Neumann, I. Laponogov, Guadalupe Gonzalez +7 more
2023Human Genomics11 citations Open access
Semantic Scholar
Optimizing Ingredient Substitution Using Large Language Models to Enhance Phytochemical Content in Recipes
Luis Rita, Joshua Southern, I. Laponogov, Kyle Higgins +1 more
2024Machine Learning and Knowledge Extraction10 citations
Semantic Scholar
Foundational Models for Pathology and Endoscopy Images: Application for Gastric Inflammation
Hamideh Kerdegari, Kyle Higgins, Dennis Veselkov, I. Laponogov +7 more
2024Diagnostics9 citations Open access
Semantic Scholar
Sub-word information in pre-trained biomedical word representations: evaluation and hyper-parameter optimization
Dieter Galea, I. Laponogov, K. Veselkov
2018Workshop on Biomedical Natural Language Processing8 citations Open access
Semantic Scholar
Translational utility of a hierarchical classification strategy in biomolecular data analytics
Dieter Galea, P. Inglese, L. Cammack, Nicole Strittmatter +7 more
2017Scientific Reports8 citations Open access
Semantic Scholar
Algorithmic Learning for Auto-deconvolution of GC-MS Data to Enable Molecular Networking within GNPS
A. Aksenov, I. Laponogov, Zheng Zhang, S. Doran +64 more
2020bioRxiv7 citations Open access
Semantic Scholar
Identifying nutraceutical targets to treat polycystic ovary syndrome using graph representation learning
S. Hanassab, Joshua Southern, Ayomide V. Olabode, I. Laponogov +7 more
2025npj Women's Health4 citations
Semantic Scholar
Genomic-driven nutritional interventions for radiotherapy-resistant rectal cancer patient
Joshua Southern, Guadalupe Gonzalez, P. Borgas, L. Poynter +6 more
2023Scientific Reports3 citations Open access
Semantic Scholar
Graph Attentional Autoencoder for Anticancer Hyperfood Prediction
Guadalupe Gonzalez, Shunwang Gong, I. Laponogov, K. Veselkov +1 more
2020arXiv.org3 citations
Semantic Scholar
Volatile organic compound (VOC) analysis to differentiate between bacterial and viral respiratory infections in COPD
Faisal Kamal, Sacheen Kumar, A. Singanayagam, M. Edwards +7 more
2018Respiratory infections3 citations
Semantic Scholar
Quinolone(Trovafloxacin)-DNA cleavage complex of gyrase from S. pneumoniae
I. Laponogov, D. Veselkov, X.-S. Pan, J. Selvarajah +3 more
20163 citations
Semantic Scholar
The Difficult Case of Crystallization and Structure Solution for the ParC55 Breakage-Reunion Domain of Topoisomerase IV from Streptococcus pneumoniae
M. Sohi, D. Veselkov, I. Laponogov, Xiao-Hui Pan +2 more
2008PLoS ONE3 citations Open access
Semantic Scholar
Learning interpretable disease self-representations for drug repositioning
Fabrizio Frasca, Diego Galeano, Guadalupe Gonzalez, I. Laponogov +3 more
2019arXiv.org2 citations
Semantic Scholar
Deep learning classification of nasal anatomical variants on computed tomography for endoscopic sinus surgery
Luis Rita, A. Rafay, Hamideh Kerdegari, Matth Kot +6 more
2026Scientific Reports1 citations Open access
Semantic Scholar
Development and validation of a diagnostic prediction model for pancreatic ductal adenocarcinoma: VAPOR 1, protocol for a prospective multicentre case–control study
C. Walsh, James Murray, I. Laponogov, Aaron G. Parker +28 more
2025BMJ Open1 citations Open access
Semantic Scholar
Studies of prokaryotic Type II topoisomerase drug inhibition
M. Sanderson, I. Laponogov, Xiao-Hui Pan, D. Veselkov +6 more
20171 citations Open access
Semantic Scholar
Insights into the mechanism for DNA capture and transport by topoisomerase II provided by the high-resolution structure of an 'open' topoisomerase II-DNA complex
I. Laponogov, D. Veselkov, I. Crevel, Xiao-Hui Pan +2 more
20131 citations Open access
Semantic Scholar
Crystallography in the study of protein–DNA interaction
M. Sohi, I. Laponogov
20071 citations
Semantic Scholar
Publisher Correction: Identifying nutraceutical targets to treat polycystic ovary syndrome using graph representation learning
S. Hanassab, Joshua Southern, Ayomide V. Olabode, I. Laponogov +7 more
2026npj Women's Health0 citations Open access
Semantic Scholar
PPI-Net connects molecular protein interactions to functional processes in disease
Kyle Higgins, Guadalupe Gonzalez, Dennis Veselkov, I. Laponogov +1 more
2026arXiv.org0 citations
Semantic Scholar
Graph neural network explanations reveal a topological signature of disease-associated hubs in biological networks
Kyle Higgins, I. Laponogov, Dennis Veselkov, K. Veselkov
2026arXiv.org0 citations
Semantic Scholar
P8 Use of machine learning in cardiopulmonary exercise testing to identify diagnosis outcomes
Jessica Swan, M. Unstead, L. Bagley, Alla Veselkova +3 more
2026Poster Abstracts0 citations Open access
Semantic Scholar
Non-invasive breath testing to detect colorectal cancer: protocol for a multicentre, case–control development and validation study (COBRA2 study)
M. Fadel, James Murray, G. Woodfield, I. Belluomo +40 more
2025BMC Cancer0 citations Open access
Semantic Scholar
P-95 - APROVECHANDO LA INTELIGENCIA ARTIFICIAL PARA PERSONALIZAR LAS RECOMENDACIONES DE TRATAMIENTO DE HELICOBACTER PYLORI: DATOS DEL REGISTRO EUROPEO SOBRE EL MANEJO DE LA INFECCIÓN POR H. PYLORI (HPEUREG)
Kyle Higgins, O. P. Nyssen, J. Southern, I. Laponogov +3 more
2025Gastroenterology & hepatology0 citations
Semantic Scholar
P695 Untargeted proteomics analysis of baseline serum samples prior to biologic therapy initiation
M. Rauch, I. Laponogov, I. van Welsen, A. Quinn +10 more
2024Journal of Crohn's & Colitis0 citations Open access
Semantic Scholar
Early Detection of Macular Atrophy Automated Through 2D and 3D Unet Deep Learning
Wei Wei, R. Patel, I. Laponogov, M. F. Cordeiro +1 more
2024Bioengineering0 citations Open access
Semantic Scholar
The Helicobacter pylori AI-Clinician: Harnessing Artificial Intelligence to Personalize H. pylori Treatment Recommendations
Kyle Higgins, O. Nyssen, Joshua Southern, I. Laponogov +5 more
2024arXiv.org0 citations
Semantic Scholar
CONSTITUTIONAL GENETIC TESTING IN PATIENTS WITH MULTIPLE COLORECTAL ADENOMAS
Sau Mak, A. Latchford, M. Hawkins, Victoria Cuthill +7 more
20230 citations
Semantic Scholar
OFR-7 Breath testing for colorectal polyps and cancer- the colorectal breath analysis1 study (COBRA1)
G. Woodfield, I. Belluomo, I. Laponogov, K. Veselkov +3 more
2021Oral0 citations Open access
Semantic Scholar

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