Researcher profile · Semantic Scholar

J. Metzger

h-index: 19
Works: 41
Citations: 1,809

Most-cited papers

A balance between secreted inhibitors and edge-sensing controls gastruloid self-organization
F. Etoc, J. Metzger, Albert Ruzo, Christoph Kirst +4 more
2016Developmental Cell328 citations Open access
Semantic Scholar
Non-equilibrium steady states of stochastic processes with intermittent resetting
S. Eule, J. Metzger
2015172 citations Open access
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A 3D model of a human epiblast reveals BMP4-driven symmetry breaking
M. Simunovic, J. Metzger, F. Etoc, Anna Yoney +6 more
2019Nature Cell Biology164 citations
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Micropattern differentiation of mouse pluripotent stem cells recapitulates embryo regionalized cell fate patterning
Sophie M. Morgani, J. Metzger, J. Nichols, E. Siggia +1 more
2018eLife155 citations Open access
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Self-organizing neuruloids model developmental aspects of Huntington’s disease in the ectodermal compartment
T. Haremaki, J. Metzger, Tiago Rito, M. Z. Ozair +2 more
2019Nature Biotechnology147 citations
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Self-organization of human embryonic stem cells on micropatterns
Alessia Deglincerti, F. Etoc, M. C. Guerra, Iain Martyn +7 more
2016Nature Protocols146 citations Open access
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Depletion of aneuploid cells in human embryos and gastruloids
Min Yang, Tiago Rito, J. Metzger, Jeffrey A Naftaly +6 more
2021Nature Cell Biology134 citations
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Random focusing of tsunami waves
H. Degueldre, J. Metzger, T. Geisel, R. Fleischmann
2015Nature Physics77 citations
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WNT signaling memory is required for ACTIVIN to function as a morphogen in human gastruloids
Anna Yoney, F. Etoc, Albert Ruzo, Thomas L. Carroll +6 more
2018bioRxiv76 citations Open access
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Chromosomal instability during neurogenesis in Huntington's disease
Albert Ruzo, Gist F. Croft, J. Metzger, Szilvia Galgoczi +8 more
2018Development56 citations
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Statistics of Extreme Waves in Random Media
J. Metzger, R. Fleischmann, T. Geisel
201344 citations Open access
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Universal statistics of branched flows.
J. Metzger, R. Fleischmann, T. Geisel
2010Physical Review Letters40 citations Open access
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Deep-learning analysis of micropattern-based organoids enables high-throughput drug screening of Huntington’s disease models
J. Metzger, Carlota Pereda, A. Adhikari, T. Haremaki +4 more
2022Cell Reports Methods38 citations Open access
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Mutant huntingtin impairs neurodevelopment in human brain organoids through CHCHD2-mediated neurometabolic failure
P. Lisowski, Selene Lickfett, A. Rybak-Wolf, Carmen Menacho +35 more
2023bioRxiv37 citations Open access
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Experimental observation of a fundamental length scale of waves in random media.
S. Barkhofen, J. Metzger, R. Fleischmann, U. Kuhl +1 more
2013Physical Review Letters35 citations Open access
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Distribution of the Fittest Individuals and the Rate of Muller's Ratchet in a Model with Overlapping Generations
J. Metzger, S. Eule
2013PLoS Comput. Biol.23 citations Open access
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How branching can change the conductance of ballistic semiconductor devices
Denis Maryenko, J. Metzger, Ragnar Fleischmann, Theo Geisel +4 more
201223 citations Open access
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Huntingtin CAG expansion impairs germ layer patterning in synthetic human 2D gastruloids through polarity defects
Szilvia Galgoczi, Albert Ruzo, Christian Markopoulos, Anna Yoney +6 more
2021bioRxiv22 citations Open access
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Synthetic embryology: controlling geometry to model early mammalian development
J. Metzger, M. Simunovic, A. Brivanlou
2018Current Opinion in Genetics and Development20 citations Open access
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Intensity fluctuations of waves in random media: what is the semiclassical limit?
J. Metzger, R. Fleischmann, T. Geisel
2013Physical Review Letters16 citations
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Channeling of Branched Flow in Weakly Scattering Anisotropic Media.
H. Degueldre, J. Metzger, Erik Schultheis, R. Fleischmann
2017Physical Review Letters14 citations
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Molecular mechanism of symmetry breaking in a 3D model of a human epiblast
M. Simunovic, J. Metzger, F. Etoc, Anna Yoney +5 more
2018bioRxiv13 citations Open access
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Branched Flow and Caustics in Two-Dimensional Random Potentials and Magnetic Fields
J. Metzger
201012 citations
Semantic Scholar
CRISPR-enabled point-of-care genotyping for APOL1 genetic risk assessment
Robert Greensmith, Isadora T. Lape, C. Riella, Alexander J Schubert +10 more
2024EMBO Molecular Medicine9 citations Open access
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Micropattern differentiation of mouse pluripotent stem cells recapitulates embryo regionalized fates and patterning
Sophie M. Morgani, J. Metzger, J. Nichols, E. Siggia +1 more
2017bioRxiv4 citations Open access
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Human organoids: Fit for drug discovery?
A. Wittich, Kim Krieg, Philip Gribbon, J. Metzger +2 more
2026Stem Cell Reports3 citations Open access
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Author Correction: Depletion of aneuploid cells in human embryos and gastruloids
Min Yang, Tiago Rito, J. Metzger, Jeffrey A Naftaly +6 more
2021Nature Cell Biology1 citations Open access
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Muller's ratchet with overlapping generations
J. Metzger, S. Eule
20131 citations Open access
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Tau spreading coordinates intercellular lipid flux enhancing neuronal resilience to lipid toxicity
Anna Oliveras Martinez, Davide Ibatici, Maria Calvo Noriega, G. Mastrobuoni +18 more
2026bioRxiv0 citations
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Generation of a human induced pluripotent stem cell line (BIHi292-A) from PBMCs of a female patient diagnosed with Nasu-Hakola disease (NHD)/polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy (PLOSL) carrying a novel heterozygous mutation in the TREM2 gene.
Ria Göttert, V. Vallone, H. Stachelscheid, J. Metzger +6 more
2025Stem Cell Research0 citations Open access
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Neurons to Words: A Novel Method for Automated Neural Network Interpretability and Alignment
Lukas-Santo Puglisi, F. Valdés, J. Metzger
2025AAAI Conference on Artificial Intelligence0 citations Open access
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Author response: WNT signaling memory is required for ACTIVIN to function as a morphogen in human gastruloids
Anna Yoney, F. Etoc, Albert Ruzo, Thomas L. Carroll +6 more
20180 citations Open access
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The Dynamics in Epithelial Cell Intercalation in Drosophila Morphogenesis
F. Wolf, L. Reichl, D. Kong, Yu-jun Zhang +3 more
20150 citations
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Stochastic Terminal Dynamics in Epithelial Cell Intercalation
S. Eule, J. Metzger, L. Reichl, D. Kong +3 more
20150 citations
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Branching of Tsunami Waves
H. Degueldre, J. Metzger, R. Fleischmann, T. Geisel
20140 citations
Semantic Scholar
Rarely clicking Muller's ratchets
S. Eule, J. Metzger
20130 citations
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Random Caustics and Intensity Fluctuations in Weakly Disordered Media
Ragnar Fleishmann, J. Metzger, T. Geisel
20120 citations
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Universal Statistics of Branched Flows
J. Metzger, R. Fleischmann, T. Geisel
20100 citations Open access
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Universal branch statistics of branched flows
J. Metzger, R. Fleischmann, T. Geisel
20100 citations
Semantic Scholar
Branched flow and caustics in random media with magnetic fields
J. Metzger, R. Fleischmann, T. Geisel
20090 citations
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1 WNT signaling memory is required for ACTIVIN to function as a morphogen in 1 human gastruloids
Anna Yoney, F. Etoc, Albert Ruzo, Thomas L. Carroll +6 more
0 citations
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E. Siggia

×9

T. Geisel×9

Anna Yoney×8

S. Eule×6

Iain Martyn×6

Christoph Kirst×4

M. Simunovic×4

Shu Li×4