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P. Sarkar · SciRah

Researcher profile · Semantic Scholar

P. Sarkar

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P. Sarkar — researcher profile on SciRah

h-index: 33
Works: 47
Citations: 2,829

Most-cited papers

Klotho Depletion Contributes to Increased Inflammation in Kidney of the db/db Mouse Model of Diabetes via RelA (Serine)536 Phosphorylation
Yan-Hua Zhao, Srijita Banerjee, N. Dey, W. Lejeune +5 more
2011Diabetes245 citations Open access
Semantic Scholar
Heterozygous loss of Six5 in mice is sufficient to cause ocular cataracts
P. Sarkar, B. Appukuttan, Jennifer Han, Yoshihiro Ito +5 more
2000Nature Genetics216 citations
Semantic Scholar
Classical non-homologous end-joining pathway utilizes nascent RNA for error-free double-strand break repair of transcribed genes
Anirban Chakraborty, N. Tapryal, T. Venkova, N. Horikoshi +5 more
2016Nature Communications155 citations Open access
Semantic Scholar
Preferential Repair of Oxidized Base Damage in the Transcribed Genes of Mammalian Cells*
D. Banerjee, S. Mandal, Aditi Das, M. Hegde +6 more
2010Journal of Biological Chemistry144 citations Open access
Semantic Scholar
Inactivation of hnRNP K by Expanded Intronic AUUCU Repeat Induces Apoptosis Via Translocation of PKCδ to Mitochondria in Spinocerebellar Ataxia 10
Misti C. White, R. Gao, Weidong Xu, S. Mandal +9 more
2010PLoS Genetics118 citations Open access
Semantic Scholar
Mutant huntingtin impairs PNKP and ATXN3, disrupting DNA repair and transcription
R. Gao, Anirban Chakraborty, Charlene Geater, Subrata Pradhan +11 more
2019eLife114 citations Open access
Semantic Scholar
Expansion of CUG RNA repeats causes stress and inhibition of translation in myotonic dystrophy 1 (DM1) cells
Claudia H. Huichalaf, K. Sakai, Bing-Wen Jin, Karlie R. Jones +7 more
2010The FASEB Journal99 citations Open access
Semantic Scholar
Neil2-null Mice Accumulate Oxidized DNA Bases in the Transcriptionally Active Sequences of the Genome and Are Susceptible to Innate Inflammation* ♦
Anirban Chakraborty, M. Wakamiya, Tatiana Venkova-Canova, R. Pandita +12 more
2015Journal of Biological Chemistry96 citations Open access
Semantic Scholar
The Role of the Mammalian DNA End-processing Enzyme Polynucleotide Kinase 3’-Phosphatase in Spinocerebellar Ataxia Type 3 Pathogenesis
A. Chatterjee, S. Saha, Anirban Chakraborty, A. Silva-Fernandes +13 more
2015PLoS Genetics95 citations Open access
Semantic Scholar
Role of Human DNA Glycosylase Nei-like 2 (NEIL2) and Single Strand Break Repair Protein Polynucleotide Kinase 3′-Phosphatase in Maintenance of Mitochondrial Genome*
S. Mandal, M. Hegde, A. Chatterjee, P. M. Hegde +8 more
2011Journal of Biological Chemistry89 citations Open access
Semantic Scholar
Reduction of the rate of Protein Translation in Patients with Myotonic Dystrophy 2
Claudia H. Huichalaf, B. Schoser, C. Schneider-Gold, Bing-Wen Jin +2 more
2009Journal of Neuroscience87 citations Open access
Semantic Scholar
Inactivation of PNKP by Mutant ATXN3 Triggers Apoptosis by Activating the DNA Damage-Response Pathway in SCA3
R. Gao, Yong-Ping Liu, A. Silva-Fernandes, Xiang Fang +10 more
2015PLoS Genetics86 citations Open access
Semantic Scholar
Myotonic dystrophy types 1 and 2.
T. Ashizawa, P. Sarkar
2011Handbook of Clinical Neurology78 citations
Semantic Scholar
Expression of RNA CCUG repeats dysregulates translation and degradation of proteins in myotonic dystrophy 2 patients.
Elizabeth Salisbury, B. Schoser, C. Schneider-Gold, Guo-Li Wang +7 more
2009American Journal of Pathology78 citations Open access
Semantic Scholar
rbFOX1/MBNL1 competition for CCUG RNA repeats binding contributes to myotonic dystrophy type 1/type 2 differences
C. Sellier, E. Cerro-Herreros, M. Blatter, F. Freyermuth +16 more
2018Nature Communications75 citations Open access
Semantic Scholar
CTG repeats show bimodal amplification in E. coli.
P. Sarkar, Haw-Chin Chang, F.Brian Boudi, S. Reddy
1998Cell73 citations Open access
Semantic Scholar
Six5 is required for spermatogenic cell survival and spermiogenesis.
P. Sarkar, Sharan Paul, Jennifer Han, S. Reddy
2004Human Molecular Genetics71 citations
Semantic Scholar
Overexpression of Smad2 reveals its concerted action with Smad4 in regulating TGF-beta-mediated epidermal homeostasis.
Yoshihiro Ito, P. Sarkar, Qing-Sheng Mi, Nancy L. Wu +6 more
2001Developmental Biology71 citations Open access
Semantic Scholar
The role of ataxin 10 in the pathogenesis of spinocerebellar ataxia type 10
M. Wakamiya, T. Matsuura, Y. Liu, G. Schuster +5 more
2006Neurology64 citations
Semantic Scholar
Structure of the Myotonic Dystrophy Type 2 RNA and Designed Small Molecules That Reduce Toxicity
Jessica L. Childs-Disney, Ilyas Yildirim, Hajeung Park, J. Lohman +5 more
2013ACS Chemical Biology58 citations Open access
Semantic Scholar
Increased Risk of Lung Cancer Associated with a Functionally Impaired Polymorphic Variant of the Human DNA Glycosylase NEIL2
S. Dey, A. Maiti, M. Hegde, P. M. Hegde +15 more
2012DNA Repair55 citations Open access
Semantic Scholar
Cytoplasmic CUG RNA Foci Are Insufficient to Elicit Key DM1 Features
W. Dansithong, C. Wolf, P. Sarkar, Sharan Paul +8 more
2008PLoS ONE53 citations Open access
Semantic Scholar
Characterization of Cardiac Conduction System Abnormalities in Mice with Targeted Disruption of Six5 Gene
H. Wakimoto, C. Maguire, M. Sherwood, Marcel M. Vargas +4 more
2002Journal of interventional cardiac electrophysiology51 citations
Semantic Scholar
Transgenic mice with SCA10 pentanucleotide repeats show motor phenotype and susceptibility to seizure — A toxic RNA gain-of-function model
Misti C. White, Guang-Bin Xia, R. Gao, M. Wakamiya +3 more
2011Journal of Neuroscience Research48 citations Open access
Semantic Scholar
Expansions, contractions, and fragility of the spinocerebellar ataxia type 10 pentanucleotide repeat in yeast
Nicole Cherng, Alexander A. Shishkin, Lucas Schlager, Ryan H Tuck +6 more
2011Proceedings of the National Academy of Sciences of the United States of America48 citations Open access
Semantic Scholar
Glucocorticoids increase skeletal muscle NF‐κB inducing kinase (NIK): links to muscle atrophy
C. Fry, Syed Z. Nayeem, E. L. Dillon, P. Sarkar +6 more
2016Physiological Reports47 citations Open access
Semantic Scholar
Klotho Ameliorates Chemically Induced Endoplasmic Reticulum (ER) Stress Signaling
Srijita Banerjee, Yan-Hua Zhao, P. Sarkar, K. Rosenblatt +2 more
2013Cellular Physiology and Biochemistry47 citations Open access
Semantic Scholar
PIAS1 modulates striatal transcription, DNA damage repair, and SUMOylation with relevance to Huntington’s disease
Eva Morozko, Charlene Smith-Geater, A. M. Monteys, Subrata Pradhan +24 more
2021Proceedings of the National Academy of Sciences of the United States of America46 citations Open access
Semantic Scholar
Design of a bioactive small molecule that targets r(AUUCU) repeats in spinocerebellar ataxia 10
Wang-Yong Yang, R. Gao, Mark R. Southern, P. Sarkar +1 more
2016Nature Communications42 citations Open access
Semantic Scholar
RNA Foci, CUGBP1, and ZNF9 are the primary targets of the mutant CUG and CCUG repeats expanded in myotonic dystrophies type 1 and type 2.
Karlie R. Jones, Bing-Wen Jin, P. Iakova, Claudia H. Huichalaf +7 more
2011American Journal of Pathology38 citations Open access
Semantic Scholar
Purkinje Cell Loss is the Major Brain Pathology of Spinocerebellar Ataxia Type 10
Guang-Bin Xia, Karen N. McFarland, Kang Wang, P. Sarkar +2 more
2013Journal of Neurology Neurosurgery & Psychiatry37 citations Open access
Semantic Scholar
Paradoxical effects of repeat interruptions on spinocerebellar ataxia type 10 expansions and repeat instability
Karen N. McFarland, Ji-Lin Liu, Ivette Landrian, R. Gao +8 more
2013European Journal of Human Genetics37 citations Open access
Semantic Scholar
Deficiency in classical nonhomologous end-joining–mediated repair of transcribed genes is linked to SCA3 pathogenesis
Anirban Chakraborty, N. Tapryal, T. Venkova, J. Mitra +11 more
2020Proceedings of the National Academy of Sciences of the United States of America34 citations Open access
Semantic Scholar
Ethanol Suppresses PGC-1α Expression by Interfering with the cAMP-CREB Pathway in Neuronal Cells
Zi-Long Liu, Yong-Ping Liu, R. Gao, Hai-Xia Li +5 more
2014PLoS ONE33 citations Open access
Semantic Scholar
In situ hybridization analysis of Dmpk mRNA in adult mouse tissues.
P. Sarkar, Jennifer Han, S. Reddy
2004Neuromuscular Disorders33 citations
Semantic Scholar
The future of cancer treatment: combining radiotherapy with immunotherapy
Gunjan Dagar, Ashna Gupta, Abhishek Shankar, Ravi D. Chauhan +10 more
2024Frontiers in Molecular Biosciences31 citations Open access
Semantic Scholar
Polyglutamine Expansion in Huntingtin and Mechanism of DNA Damage Repair Defects in Huntington’s Disease
Subrata Pradhan, R. Gao, Keegan M. Bush, Nan Zhang +2 more
2022Frontiers in Cellular Neuroscience30 citations Open access
Semantic Scholar
DNAzyme Cleavage of CAG Repeat RNA in Polyglutamine Diseases
Nan Zhang, Brittani Bewick, Jason Schultz, Anjana Tiwari +7 more
2021Neurotherapeutics12 citations Open access
Semantic Scholar
Correction: Ethanol Suppresses PGC-1α Expression by Interfering with the cAMP-CREB Pathway in Neuronal Cells
Zi-Long Liu, Yong-Ping Liu, R. Gao, Hai-Xia Li +5 more
2014PLoS ONE2 citations Open access
Semantic Scholar
Chromatin remodeler BRG1 recruits huntingtin to repair DNA double-strand breaks in neurons
Subrata Pradhan, Keegan M. Bush, Nan Zhang, R. Pandita +17 more
2024bioRxiv1 citations
Semantic Scholar
The role of human DNA glycosylase NEIL 2 and the single-strand break repair protein polynucleotide kinase 3 '-phosphatase in maintenance of the mitochondrial genome
S. Mandal, M. Hegde, A. Chatterjee, P. M. Hegde +8 more
20111 citations
Semantic Scholar
A novel approach to design of cis-acting DNA structural element for regulation of gene expression in vivo
P. Sarkar, Rajesh Bagga, P. Balagurumoorthy, Samir K Bramachari
19911 citations
Semantic Scholar
Correction: The Role of the Mammalian DNA End-processing Enzyme Polynucleotide Kinase 3’-Phosphatase in Spinocerebellar Ataxia Type 3 Pathogenesis
Arpita Chatterjee, Saikat Saha, Anirban Chakraborty, A. Silva-Fernandes +13 more
2024PLoS Genetics0 citations Open access
Semantic Scholar
Huntingtin Maintains Mitochondrial Genome Integrity and Function
Subrata Pradhan, R. Gao, Keegan M. Bush, Nan Zhang +16 more
2021Social Science Research Network0 citations Open access
Semantic Scholar
Author response: Mutant huntingtin impairs PNKP and ATXN3, disrupting DNA repair and transcription
R. Gao, Anirban Chakraborty, Charlene Geater, Subrata Pradhan +11 more
20190 citations Open access
Semantic Scholar
Mutant Ataxin‐3 inhibits 3’ phosphatase activity of human polynucleotide kinase 3′‐phosphatase (PNKP)
Saikat Saha, A. Chatterjee, S. K. Mandal, R. Gao +5 more
20130 citations
Semantic Scholar
Mutant huntingtin impairs PNKP and ATXN 3 , disrupting DNA repair and transcription 1 2 3
R. Gao, Anirban Chakraborty, Charlene Geater, Subrata Pradhan +13 more
0 citations
Semantic Scholar

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