Researcher profile · Semantic Scholar

Owen S. Fenton

h-index: 25
Works: 40
Citations: 4,899

Most-cited papers

Optimization of Lipid Nanoparticle Formulations for mRNA Delivery in Vivo with Fractional Factorial and Definitive Screening Designs.
Kevin J. Kauffman, J. R. Dorkin, Junghoon Yang, M. Heartlein +4 more
2015Nano letters (Print)716 citations
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Advances in Biomaterials for Drug Delivery
Owen S. Fenton, Katy N. Olafson, Padmini S. Pillai, M. J. Mitchell +1 more
2018Advances in Materials695 citations Open access
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Lipid Nanoparticle Assisted mRNA Delivery for Potent Cancer Immunotherapy
M. Oberli, A. Reichmuth, J. R. Dorkin, M. J. Mitchell +5 more
2016Nano letters (Print)652 citations Open access
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Degradable Lipid Nanoparticles with Predictable In Vivo siRNA Delivery Activity
Kathryn A. Whitehead, J. R. Dorkin, A. Vegas, P. Chang +12 more
2014Nature Communications549 citations Open access
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Polymer-Lipid Nanoparticles for Systemic Delivery of mRNA to the Lungs
James C. Kaczmarek, A. Patel, Kevin J. Kauffman, Owen S. Fenton +4 more
2016Angewandte Chemie310 citations Open access
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Synthesis and Biological Evaluation of Ionizable Lipid Materials for the In Vivo Delivery of Messenger RNA to B Lymphocytes
Owen S. Fenton, Kevin J. Kauffman, James C. Kaczmarek, Rebecca L. McClellan +12 more
2017Advances in Materials243 citations Open access
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Bioinspired Alkenyl Amino Alcohol Ionizable Lipid Materials for Highly Potent in vivo mRNA Delivery
Owen S. Fenton, Kevin J. Kauffman, Rebecca L. McClellan, Eric A. Appel +6 more
2016Advances in Materials237 citations Open access
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Optimization of a Degradable Polymer-Lipid Nanoparticle for Potent Systemic Delivery of mRNA to the Lung Endothelium and Immune Cells
James C. Kaczmarek, Kevin J. Kauffman, Owen S. Fenton, Kaitlyn Sadtler +4 more
2018Nano letters (Print)193 citations Open access
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Biomanufacturing for clinically advanced cell therapies
A. Aijaz, Matthew Li, David Smith, D. Khong +12 more
2018Nature Biomedical Engineering172 citations Open access
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Customizable Lipid Nanoparticle Materials for the Delivery of siRNAs and mRNAs
Owen S. Fenton, Kevin J. Kauffman, Rebecca L. McClellan, James C. Kaczmarek +6 more
2018Angewandte Chemie115 citations Open access
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Exploiting Electrostatic Interactions in Polymer–Nanoparticle Hydrogels
E. Appel, M. Tibbitt, Jessica M. Greer, Owen S. Fenton +3 more
2015ACS Macro Letters102 citations Open access
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A Nanoprimer to improve the systemic delivery of siRNA and mRNA.
Nell Saunders, Marion S. Paolini, Owen S. Fenton, L. Poul +7 more
2020Nano letters (Print)88 citations
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Engineering a 3D-Bioprinted Model of Human Heart Valve Disease Using Nanoindentation-Based Biomechanics
D. C. van der Valk, C. F. T. van der Ven, M. Blaser, Joshua M. Grolman +17 more
2018Nanomaterials81 citations Open access
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Engineering nanoparticle toolkits for mRNA delivery.
Bing Sun, Wei-Xi Wu, Eshan A Narasipura, Yutian Ma +3 more
2023Advanced Drug Delivery Reviews77 citations Open access
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C7-Derivatization of C3-Alkylindoles Including Tryptophans and Tryptamines
Richard P. Loach, Owen S. Fenton, Kazuma Amaike, D. Siegel +2 more
2014Journal of Organic Chemistry74 citations Open access
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Poly(β-amino ester)-co-poly(caprolactone) Terpolymers as Nonviral Vectors for mRNA Delivery In Vitro and In Vivo
U. C. Palmiero, James C. Kaczmarek, Owen S. Fenton, Daniel G. Anderson
2018Advanced Healthcare Materials73 citations Open access
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Injectable Polymer-Nanoparticle Hydrogels for Local Immune Cell Recruitment.
Owen S. Fenton, M. Tibbitt, E. Appel, S. Jhunjhunwala +2 more
2019Biomacromolecules66 citations
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Concise Total Synthesis of (+)-Asperazine, (+)-Pestalazine A, and (+)-iso-Pestalazine A. Structure Revision of (+)-Pestalazine A
Richard P. Loach, Owen S. Fenton, M. Movassaghi
2016Journal of the American Chemical Society54 citations Open access
Semantic Scholar
Ongoing Clinical Trials of Nonviral siRNA Therapeutics.
Eshan A Narasipura, Rachel VanKeulen‐Miller, Yutian Ma, Owen S. Fenton
2023Bioconjugate chemistry52 citations
Semantic Scholar
β-Aminoacrylate Synthetic Hydrogels: Easily Accessible and Operationally Simple Biomaterials Networks.
Owen S. Fenton, Jason L. Andresen, Marion S. Paolini, R. Langer
2018Angewandte Chemie52 citations
Semantic Scholar
Rapid Classification of Simulated Street Drug Mixtures Using Raman Spectroscopy and Principal Component Analysis
Kathryn Y. Noonan, Lindsey A. Tonge, Owen S. Fenton, David B. Damiano +1 more
2009Applied Spectroscopy41 citations
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An Efficacy and Mechanism Driven Study on the Impact of Hypoxia on Lipid Nanoparticle Mediated mRNA Delivery
Yutian Ma, Owen S. Fenton
2023Journal of the American Chemical Society39 citations
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Polymers for extended-release administration
Marion S. Paolini, Owen S. Fenton, Chandrabali Bhattacharya, Jason L. Andresen +1 more
2019Biomedical microdevices39 citations Open access
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Tannic Acid Lipid Nanoparticles can Deliver Messenger RNA Payloads and Improve their Endosomal Escape
Yutian Ma, Owen S. Fenton
2023Advances in Therapy36 citations
Semantic Scholar
Nucleic acid delivery and nanoparticle design for COVID vaccines
Jason L. Andresen, Owen S. Fenton
2021MRS bulletin25 citations Open access
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Poly(limonene thioether) Scaffold for Tissue Engineering
K. Fischer, Kathy Ye Morgan, Keith Hearon, Demetra Sklaviadis +5 more
2016Advanced Healthcare Materials22 citations Open access
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Catalytic Lewis acid phosphorylation with pyrophosphates
Owen S. Fenton, E. E. Allen, Kyle Pedretty, Sean D. Till +2 more
201220 citations
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Quantitative Analysis of Simulated Illicit Street-Drug Samples Using Raman Spectroscopy and Partial Least Squares Regression
Owen S. Fenton, Lindsey A. Tonge, Taylor H. Moot, Kimberley Frederick
201120 citations
Semantic Scholar
Efficient catalyst turnover in the phosphitylation of alcohols with phosphoramidites
P. Brady, E. Morris, Owen S. Fenton, Bianca R. Sculimbrene
200918 citations
Semantic Scholar
Outlooks on Three-Dimensional Printing for Ocular Biomaterials Research
Owen S. Fenton, Marion S. Paolini, Jason L. Andresen, Florence J. Müller +1 more
2020Journal of Ocular Pharmacology and Therapeutics17 citations Open access
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“Enhancing the Functionality of Immunoisolated Human SC-βeta Cell Clusters through Prior Resizing”
Matthew A. Bochenek, Ben Walters, Jingping Zhang, Owen S. Fenton +9 more
2024Small9 citations
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A Wet-Lab Approach to Stereochemistry Using 31P NMR Spectroscopy
Owen S. Fenton, Bianca R. Sculimbrene
20119 citations
Semantic Scholar
Additive Manufacturing Approaches toward the Fabrication of Biomaterials
Florence J. Müller, Owen S. Fenton
2022Advanced Materials Interfaces6 citations
Semantic Scholar
Single-tailed Heterocyclic Carboxamide Lipids for Macrophage Immune-Modulation
Kuo-Ching Mei, R. Stiepel, Emily E. Bonacquisti, Natalie E. Jasiewicz +6 more
2023Biomaterials Science4 citations Open access
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Design, synthesis, and biological evaluation of diketopiperazine based ionizable lipids for the in vivo delivery of messenger RNA
Owen S. Fenton
20161 citations
Semantic Scholar
Nucleic acid delivery and nanoparticle design for COVID vaccines
Jason L. Andresen, Owen S. Fenton
20210 citations Open access
Semantic Scholar
Catalytic Lewis Acid Phosphorylation with Pyrophosphates.
Owen S. Fenton, E. E. Allen, Kyle Pedretty, Sean D. Till +2 more
20130 citations
Semantic Scholar
A general entry to C7-borono indole derivatives
Owen S. Fenton
20120 citations
Semantic Scholar
Efficient Catalyst Turnover in the Phosphitylation of Alcohols with Phosphoramidites.
P. Brady, E. Morris, Owen S. Fenton, Bianca R. Sculimbrene
20090 citations
Semantic Scholar
Optimization of a Degradable Polymer − Lipid Nanoparticle for Potent Systemic Delivery of mRNA to the Lung Endothelium and Immune Cells
James C. Kaczmarek, K. F. man, Owen S. Fenton, Kaitlyn Sadtler +4 more
0 citations
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×6

M. Tibbitt×5

Bianca R. Sculimbrene×5

J. R. Dorkin×4

Marion S. Paolini×4