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J. Dziegielewski · SciRah

Researcher profile · Semantic Scholar

J. Dziegielewski

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J. Dziegielewski — researcher profile on SciRah

h-index: 21
Works: 39
Citations: 1,766

Most-cited papers

The cell-cycle checkpoint kinase Chk1 is required for mammalian homologous recombination repair
C. Sørensen, L. Hansen, J. Dziegielewski, R. Syljuåsen +3 more
2005Nature Cell Biology686 citations
Semantic Scholar
T-type calcium channels blockers as new tools in cancer therapies
Barbara Dziegielewska, L. Gray, J. Dziegielewski
2014Pflügers Archiv: European Journal of Physiology107 citations
Semantic Scholar
Activation of DNA-PK by Ionizing Radiation Is Mediated by Protein Phosphatase 6
J. Mi, J. Dziegielewski, E. Bolesta, D. Brautigan +1 more
2009PLoS ONE97 citations Open access
Semantic Scholar
Inhibition of T-type calcium channels disrupts Akt signaling and promotes apoptosis in glioblastoma cells.
N. Valerie, Barbara Dziegielewska, Amol S. Hosing, E. Augustin +4 more
2013Biochemical Pharmacology91 citations
Semantic Scholar
RPA mediates recombination repair during replication stress and is displaced from DNA by checkpoint signalling in human cells.
Kate M. Sleeth, C. Sørensen, N. Issaeva, J. Dziegielewski +2 more
2007Journal of Molecular Biology83 citations
Semantic Scholar
Lack of evidence for low-LET radiation induced bystander response in normal human fibroblasts and colon carcinoma cells
M. Sowa, W. Goetz, J. Baulch, Dinah N Pyles +6 more
2010International Journal of Radiation Biology65 citations
Semantic Scholar
T-type Ca2+ channel inhibition sensitizes ovarian cancer to carboplatin
Barbara Dziegielewska, E. Casarez, Wesley Z. Yang, L. Gray +2 more
2016Molecular Cancer Therapeutics61 citations Open access
Semantic Scholar
The Relationship Between Mismatch Repair Deficiency and PD-L1 Expression in Breast Carcinoma
A. Mills, E. Dill, C. Moskaluk, J. Dziegielewski +2 more
2018American Journal of Surgical Pathology59 citations Open access
Semantic Scholar
DNA crosslinking and biological activity of a hairpin polyamide-chlorambucil conjugate.
Yong-dong Wang, J. Dziegielewski, Nicholas R. Wurtz, Barbara Dziegielewska +2 more
2003Nucleic Acids Research54 citations Open access
Semantic Scholar
T-Type Ca2+ Channel Inhibition Induces p53-Dependent Cell Growth Arrest and Apoptosis through Activation of p38-MAPK in Colon Cancer Cells
Barbara Dziegielewska, D. Brautigan, J. Larner, J. Dziegielewski
2013Molecular Cancer Research50 citations
Semantic Scholar
Inhibition of neurotensin receptor 1 selectively sensitizes prostate cancer to ionizing radiation.
N. Valerie, E. Casarez, J. DaSilva, M. Dunlap-Brown +3 more
2011Cancer Research49 citations Open access
Semantic Scholar
WR-1065, the Active Metabolite of Amifostine, Mitigates Radiation-Induced Delayed Genomic Instability
J. Dziegielewski, J. Baulch, W. Goetz, M. Coleman +4 more
2008Free Radical Biology & Medicine49 citations Open access
Semantic Scholar
Intercalation of imidazoacridinones to DNA and its relevance to cytotoxic and antitumor activity.
J. Dziegielewski, B. Ślusarski, A. Konitz, A. Składanowski +1 more
2002Biochemical Pharmacology46 citations
Semantic Scholar
PP6 Regulatory Subunit R1 Is Bidentate Anchor for Targeting Protein Phosphatase-6 to DNA-dependent Protein Kinase*
Amol S. Hosing, N. Valerie, J. Dziegielewski, D. Brautigan +1 more
2012Journal of Biological Chemistry38 citations Open access
Semantic Scholar
Heavy ions, radioprotectors and genomic instability: implications for human space exploration
J. Dziegielewski, W. Goetz, J. Baulch
2010Radiation and Environmental Biophysics31 citations
Semantic Scholar
Enzymatic activation of a new antitumour drug, 5-diethylaminoethylamino-8-hydroxyimidazoacridinone, C-1311, observed after its intercalation into DNA.
Z. Mazerska, J. Dziegielewski, J. Konopa
2001Biochemical Pharmacology30 citations
Semantic Scholar
Cellular Responses to the DNA Strand-scission Enediyne C-1027 Can Be Independent of ATM, ATR, and DNA-PK Kinases*
J. Dziegielewski, T. Beerman
2002Journal of Biological Chemistry28 citations Open access
Semantic Scholar
Cyclophilin B expression is associated with in vitro radioresistance and clinical outcome after radiotherapy.
Paul D. Williams, Charles R. Owens, J. Dziegielewski, C. Moskaluk +7 more
2011Neoplasia27 citations Open access
Semantic Scholar
Cell-free and Cellular Activities of a DNA Sequence Selective Hairpin Polyamide-CBI Conjugate*
Yong-dong Wang, J. Dziegielewski, Aileen Y. Chang, P. Dervan +1 more
2002Journal of Biological Chemistry25 citations Open access
Semantic Scholar
QSAR of acridines, III. Structure-activity relationship for antitumour imidazoacridinones and intercorrelations between in vivo and in vitro tests.
Z. Mazerska, E. Augustin, J. Dziegielewski, M. Cholody +1 more
1996Anti-Cancer Drug Design22 citations
Semantic Scholar
Checkpoint kinase 2 (CHK2) negatively regulates androgen sensitivity and prostate cancer cell growth
Huy Q. Ta, Melissa L. Ivey, H. Frierson, M. Conaway +3 more
2015Cancer Research21 citations Open access
Semantic Scholar
The genome factor in region-specific DNA damage: the DNA-reactive drug U-78779 prefers mixed A/T-G/C sequences at the nucleotide level but is region-specific for long pure AT islands at the genomic level.
M. Herzig, K. Rodriguez, A. V. Trevino, J. Dziegielewski +3 more
2002Biochemistry13 citations
Semantic Scholar
Bleomycin-induced alterations in DNA replication: relationship to DNA damage.
J. Dziegielewski, T. Melendy, T. Beerman
2001Biochemistry13 citations
Semantic Scholar
Amifostine Metabolite WR-1065 Disrupts Homologous Recombination in Mammalian Cells
J. Dziegielewski, W. Goetz, J. Murley, D. Grdina +2 more
2010Radiation Research10 citations Open access
Semantic Scholar
Deletion of the SAPS1 subunit of protein phosphatase 6 in mice increases radiosensitivity and impairs the cellular DNA damage response.
J. Dziegielewski, M. Bońkowska, Ewa A Poniecka, Jinho Heo +5 more
2019DNA Repair7 citations
Semantic Scholar
Abstract 5407: T-type Ca2+ channel inhibitors sensitize ovarian cancer to carboplatin through downregulation of survivin gene expression
Barbara Dziegielewska, E. Casarez, Wesley Z. Yang, J. Dziegielewski +1 more
20152 citations
Semantic Scholar
Abstract LB-262: Targeting T-type calcium channels induces the extrinsic apoptotic pathway and sensitizes glioblastoma cancer cells to radio- and chemotherapy
J. Dziegielewski, N. Valerie, Barbara Dziegielewska, Amol S. Hosing +2 more
20121 citations
Semantic Scholar
The Specific Neurotensin Receptor (ntr1) Antagonist, Sr48692, Sensitizes Prostate Cancer Cells to Ionizing Radiation, in Both In Vitro and In Vivo Models
J. Larner, J. Dziegielewski, Bradley Pemberton, Marya E. Dunlap-Brown +2 more
20091 citations Open access
Semantic Scholar
Abstract P3-07-03: Targeting low voltage-activated calcium channels in HER2-positive breast cancer
Barbara Dziegielewska, M. Dunlap-Brown, W. Warnock, P. Dillon +2 more
20180 citations
Semantic Scholar
Low Voltage Activated Calcium Channels - Their Role in HER2 Driven Breast Cancer and Potential as a New Therapeutic Target
J. Dziegielewski
20160 citations
Semantic Scholar
Abstract 5049: Checkpoint kinase 2 is a novel regulator of prostate cancer cell growth
Huy Q. Ta, Melissa L. Ivey, H. Frierson, M. Conaway +3 more
20150 citations
Semantic Scholar
Abstract 750: Overcoming resistance to anti-EGFR therapy in non-small cell lung cancer with a T-type Ca2+ channels inhibitor
Barbara Dziegielewska, L. Gray, J. Dziegielewski
20150 citations
Semantic Scholar
Abstract 1808: Enhancing the Stupp regimen in glioblastoma cancer cells with a T-type calcium channels inhibitor
J. Dziegielewski, Barbara Dziegielewska, L. Gray
20150 citations
Semantic Scholar
Cell Death and Survival T-Type Ca 2 þ Channel Inhibition Induces p 53-Dependent Cell Growth Arrest and Apoptosis through Activation of p 38-MAPK in Colon Cancer Cells
Barbara Dziegielewska, D. Brautigan, J. Larner, J. Dziegielewski
20140 citations
Semantic Scholar
Abstract A239: T-type calcium channels as a novel molecular target for tumor therapy.
Barbara Dziegielewska, N. Valerie, Amol S. Hosing, J. Larner +3 more
20130 citations
Semantic Scholar
Regulatory Subunit R 1 Is Bidentate Anchor for Targeting Protein Phosphatase-6 to DNA-dependent Protein Kinase *
Amol S. Hosing, N. Valerie, J. Dziegielewski, D. Brautigan +1 more
20120 citations
Semantic Scholar
Abstract 2505: Neurotensin receptor antagonist, SR48692, sensitizes prostate cancer cells to radiationin vitroandin vivo
E. Casarez, J. DaSilva, N. Valerie, Suresh Anaganti +5 more
20110 citations
Semantic Scholar
Mechanisms of Radiosensitization by the Neurotensin Receptor Antagonist SR48692 in Prostate Cancer Models
J. Dziegielewski, N. Valerie, J. DaSilva, Eli V. Casarez +4 more
20090 citations Open access
Semantic Scholar
[Water from flower vases as a reservoir of opportunistic microorganisms in a hospital environment].
H. Perkowski, D. Dzierżanowska, M. Kaczyńska, J. Dziegielewski +1 more
1975Przeglad Epidemiologiczny0 citations
Semantic Scholar

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Barbara Dziegielewska×12
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