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Jackson Champer · SciRah

Researcher profile · Semantic Scholar

Jackson Champer

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Jackson Champer — researcher profile on SciRah

h-index: 25
Works: 81
Citations: 2,565

Most-cited papers

Cheating evolution: engineering gene drives to manipulate the fate of wild populations
Jackson Champer, Anna B. Buchman, O. Akbari
2016Nature reviews genetics441 citations Open access
Semantic Scholar
Novel CRISPR/Cas9 gene drive constructs reveal insights into mechanisms of resistance allele formation and drive efficiency in genetically diverse populations
Jackson Champer, Riona Reeves, S. Oh, Chen Liu +3 more
2017PLoS Genetics258 citations Open access
Semantic Scholar
Reducing resistance allele formation in CRISPR gene drive
Jackson Champer, Jingxian Liu, S. Oh, Riona Reeves +4 more
2018Proceedings of the National Academy of Sciences of the United States of America238 citations Open access
Semantic Scholar
A toxin-antidote CRISPR gene drive system for regional population modification
Jackson Champer, Esther Lee, Emily Yang, Chen Liu +2 more
2020Nature Communications116 citations Open access
Semantic Scholar
Computational and experimental performance of CRISPR homing gene drive strategies with multiplexed gRNAs
Samuel E. Champer, S. Oh, Chen Liu, Zhao-Xin Wen +3 more
2019Science Advances109 citations Open access
Semantic Scholar
Molecular safeguarding of CRISPR gene drive experiments
Jackson Champer, Joan Chung, Yoo Lim Lee, Chen Liu +4 more
2018bioRxiv104 citations Open access
Semantic Scholar
A CRISPR homing gene drive targeting a haplolethal gene removes resistance alleles and successfully spreads through a cage population
Jackson Champer, Emily Yang, Esther Lee, Jingxian Liu +2 more
2020Proceedings of the National Academy of Sciences of the United States of America95 citations Open access
Semantic Scholar
Performance analysis of novel toxin-antidote CRISPR gene drive systems
Jackson Champer, Isabel K. Kim, Samuel E. Champer, A. Clark +1 more
2019BMC Biology91 citations Open access
Semantic Scholar
Core commitments for field trials of gene drive organisms
Kanya Long, L. Alphey, G. Annas, C. Bloss +40 more
2020Science89 citations Open access
Semantic Scholar
Suppression gene drive in continuous space can result in unstable persistence of both drive and wild-type alleles
Jackson Champer, Isabel K. Kim, Samuel E. Champer, A. Clark +1 more
2019bioRxiv85 citations Open access
Semantic Scholar
Symbionts and gene drive: two strategies to combat vector-borne disease.
Guan-Hong Wang, Jie Du, Chen-Yi Chu, M. Madhav +2 more
2022Trends in Genetics71 citations Open access
Semantic Scholar
A homing suppression gene drive with multiplexed gRNAs maintains high drive conversion efficiency and avoids functional resistance alleles
Emily Yang, Matthew Metzloff, A. M. Langmüller, Xuejiao Xu +3 more
2021bioRxiv58 citations Open access
Semantic Scholar
Population Dynamics of Underdominance Gene Drive Systems in Continuous Space
Jackson Champer, Joanna Zhao, Samuel E. Champer, Jingxian Liu +1 more
2018bioRxiv58 citations Open access
Semantic Scholar
Modeling CRISPR gene drives for suppression of invasive rodents using a supervised machine learning framework
Samuel E. Champer, Nathan Oakes, Ronin Sharma, P. García‐Díaz +2 more
2020bioRxiv37 citations Open access
Semantic Scholar
CRISPR Gene Drive Efficiency and Resistance Rate Is Highly Heritable with No Common Genetic Loci of Large Effect
Jackson Champer, Zhao-Xin Wen, A. Luthra, Riona Reeves +7 more
2019Genetics36 citations Open access
Semantic Scholar
Gene Drive and Symbiont Technologies for Control of Mosquito-Borne Diseases.
Guan-Hong Wang, Ary Hoffmann, Jackson Champer
2024Annual Review of Entomology35 citations Open access
Semantic Scholar
Maximum Likelihood Estimation of Fitness Components in Experimental Evolution
Jingxian Liu, Jackson Champer, A. M. Langmüller, Chen Liu +7 more
2019Genetics35 citations Open access
Semantic Scholar
Design and analysis of CRISPR-based underdominance toxin-antidote gene drives
Jackson Champer, Samuel E. Champer, Isabel K. Kim, A. Clark +1 more
2019bioRxiv34 citations Open access
Semantic Scholar
Germline Cas9 promoters with improved performance for homing gene drive
Jie Du, Weizhe Chen, Xihua Jia, Xuejiao Xu +6 more
2024Nature Communications33 citations Open access
Semantic Scholar
Experimental demonstration of tethered gene drive systems for confined population modification or suppression
Matthew Metzloff, Emily Yang, Sumit Dhole, A. Clark +2 more
2021bioRxiv33 citations Open access
Semantic Scholar
Anopheles homing suppression drive candidates exhibit unexpected performance differences in simulations with spatial structure
Samuel E. Champer, Isabel K. Kim, A. Clark, Philipp W. Messer +1 more
2022eLife31 citations Open access
Semantic Scholar
Population suppression by release of insects carrying a dominant sterile homing gene drive targeting doublesex in Drosophila
Weizhe (Wesley) Chen, Jia-Liang Guo, Yi-Ran Liu, Jackson Champer
2023bioRxiv30 citations Open access
Semantic Scholar
Modelling homing suppression gene drive in haplodiploid organisms
Yi-Ran Liu, Jackson Champer
2021bioRxiv30 citations Open access
Semantic Scholar
Gene drive-based population suppression in the malaria vector Anopheles stephensi
Xuejiao Xu, Jing-Heng H. Chen, You Wang, Yi-Ran Liu +6 more
2024bioRxiv26 citations Open access
Semantic Scholar
Overriding Mendelian inheritance in Arabidopsis with a CRISPR toxin-antidote gene drive that impairs pollen germination
Yang Liu, Bingke Jiao, Jackson Champer, Wenfeng Qian
2023bioRxiv25 citations
Semantic Scholar
Adversarial interspecies relationships facilitate population suppression by gene drive in spatially explicit models
Yi-Ran Liu, Weijian Teo, Haochen Yang, Jackson Champer
2022bioRxiv24 citations Open access
Semantic Scholar
Design and analysis of CRISPR‐based underdominance toxin‐antidote gene drives
Jackson Champer, Samuel E. Champer, Isabel K. Kim, A. Clark +1 more
2020Evolutionary Applications23 citations Open access
Semantic Scholar
Genetic control of invasive sea lamprey in the Great Lakes
D. Ferreira-Martins, Jackson Champer, D. W. McCauley, Zhe Zhang +1 more
2021Journal of Great Lakes research21 citations Open access
Semantic Scholar
Fitness effects of CRISPR endonucleases in Drosophila melanogaster populations
A. M. Langmüller, Jackson Champer, Sandra Lapinska, Lin Xie +7 more
2021bioRxiv20 citations Open access
Semantic Scholar
A Comparative Assessment of Self-limiting Genetic Control Strategies for Population Suppression
Yue Han, Jackson Champer
2024bioRxiv18 citations Open access
Semantic Scholar
Harnessing Wolbachia cytoplasmic incompatibility alleles for confined gene drive: A modeling study
Jiahe Li, Jackson Champer
2022bioRxiv18 citations Open access
Semantic Scholar
Assessment of distant-site rescue elements for CRISPR toxin-antidote gene drives
Jing-Heng H. Chen, Xuejiao Xu, Jackson Champer
2023bioRxiv16 citations Open access
Semantic Scholar
Improving the suppressive power of homing gene drive by co-targeting a distant-site female fertility gene
Nicky R. Faber, Xuejiao Xu, Jing-Heng H. Chen, Shibo Hou +5 more
2023bioRxiv16 citations Open access
Semantic Scholar
A homing rescue gene drive with multiplexed gRNAs reaches high frequency in cage populations but generates functional resistance
Shibo Hou, Jing-Heng H. Chen, Ruobing Feng, Xuejiao Xu +2 more
2023bioRxiv16 citations Open access
Semantic Scholar
Novel CRISPR/Cas9 gene drive constructs in Drosophila reveal insights into mechanisms of resistance allele formation and drive efficiency in genetically diverse populations
Jackson Champer, Riona Reeves, Suh Yeon Oh, Chen Liu +3 more
2017bioRxiv16 citations Open access
Semantic Scholar
Simulations reveal high efficiency and confinement of a population suppression CRISPR toxin-antidote gene drive
Yu-Tong Zhu, Jackson Champer
2022bioRxiv15 citations Open access
Semantic Scholar
Resistance is futile: A CRISPR homing gene drive targeting a haplolethal gene
Jackson Champer, Emily Yang, Yoo Lim Lee, Jingxian Liu +2 more
2019bioRxiv13 citations Open access
Semantic Scholar
Battles between ants (Hymenoptera: Formicidae): a review
Jackson Champer, Debra Schlenoff
2024Journal of Insect Science12 citations Open access
Semantic Scholar
Population dynamics in spatial suppression gene drive models and the effect of resistance, density dependence, and life history
Xin-Yu Zhang, Weitang Sun, Isabel K. Kim, Philipp W. Messer +1 more
2024bioRxiv11 citations Open access
Semantic Scholar
Population suppression with dominant female-lethal alleles is boosted by homing gene drive
Jin-Yu Zhu, Jing-Heng H. Chen, Yi-Ran Liu, Xuejiao Xu +1 more
2023bioRxiv11 citations Open access
Semantic Scholar
Reducing resistance allele formation in CRISPR gene drives
Jackson Champer, Jingxian Liu, S. Oh, Riona Reeves +4 more
2017bioRxiv10 citations Open access
Semantic Scholar
Making waves: Comparative analysis of gene drive spread characteristics in a continuous space model
Mingzuyu Pan, Jackson Champer
2022bioRxiv9 citations Open access
Semantic Scholar
A small-molecule approach to restore female sterility phenotype targeted by a homing suppression gene drive in the fruit pest Drosophila suzukii
Suhan Ma, Xu-Yang Ni, Shimin Chen, Xiao-Mu Qiao +4 more
2024PLoS Genetics8 citations Open access
Semantic Scholar
Multiple loci of small effect confer wide variability in efficiency and resistance rate of CRISPR gene drive
Jackson Champer, Zhao-Xin Wen, A. Luthra, Riona Reeves +7 more
2018bioRxiv8 citations Open access
Semantic Scholar
Assessing target genes for homing suppression gene drive
Xuejiao Xu, Jialing Fang, Jing-Heng H. Chen, Jie Yang +4 more
2025bioRxiv7 citations Open access
Semantic Scholar
Strategies to improve the efficiency of homing gene drives with multiplexed gRNAs
Weizhe Chen, Pei-Xin Wu, Jackson Champer
2025bioRxiv6 citations Open access
Semantic Scholar
New germline Cas9 promoters show improved performance for homing gene drive
Jie Du, Weizhe (Wesley) Chen, Xi-Hua Jia, Xuejiao Xu +6 more
2023bioRxiv6 citations Open access
Semantic Scholar
Gene drives and other transgenic approaches for mosquito control.
Weizhe Chen, Xiao-Zhen Yang, Jialiang Guo, Yue Han +1 more
2026Trends in Parasitology5 citations
Semantic Scholar
Stronger population suppression by gene drive targeting doublesex from dominant female-sterile resistance alleles
Weizhe Chen, Zi-Ye Wang, Jackson Champer
2025bioRxiv5 citations Open access
Semantic Scholar
Assessment of drive efficiency and resistance allele formation of a homing gene drive in the mosquito Aedes aegypti
Xiao-Zhen Yang, Xuejiao Xu, Yi-Xian Chen, Jiajia Wei +4 more
2024bioRxiv5 citations
Semantic Scholar

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Emily Yang×10
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Samuel E. Champer×8

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Riona Reeves×7

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Jing-Heng H. Chen×6

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