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Megumi Takeuchi · SciRah

Researcher profile · Semantic Scholar

Megumi Takeuchi

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Megumi Takeuchi — researcher profile on SciRah

h-index: 11
Works: 17
Citations: 489

Most-cited papers

O-Glycosylation modulates the stability of epidermal growth factor-like repeats and thereby regulates Notch trafficking
H. Takeuchi, Hongjun Yu, Huilin Hao, Megumi Takeuchi +3 more
2017Journal of Biological Chemistry101 citations Open access
Semantic Scholar
Two novel protein O-glucosyltransferases that modify sites distinct from POGLUT1 and affect Notch trafficking and signaling
H. Takeuchi, Michael Schneider, Daniel B. Williamson, Atsuko Ito +3 more
2018Proceedings of the National Academy of Sciences of the United States of America86 citations Open access
Semantic Scholar
Notch-modifying xylosyltransferase-substrate complexes support an SNi-like retaining mechanism
Hongjun Yu, Megumi Takeuchi, J. LeBarron, Joshua Kantharia +5 more
2015Nature Chemical Biology61 citations Open access
Semantic Scholar
Genetic and biochemical evidence that gastrulation defects in Pofut2 mutants result from defects in ADAMTS9 secretion
Brian Benz, Sumeda Nandadasa, Megumi Takeuchi, R. C. Grady +7 more
2016Developmental Biology43 citations Open access
Semantic Scholar
Heterogeneous mutations in the glycogen-debranching enzyme gene are responsible for glycogen storage disease type IIIa in Japan
M. Okubo, A. Horinishi, Megumi Takeuchi, Yoshimi Suzuki +10 more
1999Human Genetics37 citations
Semantic Scholar
Structural analysis of Notch-regulating Rumi reveals basis for pathogenic mutations
Hongjun Yu, H. Takeuchi, Megumi Takeuchi, Qun Liu +3 more
2016Nature Chemical Biology35 citations Open access
Semantic Scholar
ADAMTS9 and ADAMTS20 are differentially affected by loss of B3GLCT in a mouse model of Peters Plus Syndrome.
B. Holdener, C. Percival, R. C. Grady, Daniel C Cameron +14 more
2019Human Molecular Genetics27 citations Open access
Semantic Scholar
Variant in human POFUT1 reduces enzymatic activity and likely causes a recessive microcephaly, global developmental delay with cardiac and vascular features
H. Takeuchi, Derek Wong, Michael Schneider, H. Freeze +6 more
2018Glycobiology27 citations Open access
Semantic Scholar
Asparagine Tautomerization in Glycosyltransferase Catalysis. The Molecular Mechanism of Protein O-Fucosyltransferase 1
Beatriz Piniello, E. Lira-Navarrete, H. Takeuchi, Megumi Takeuchi +3 more
2021ACS Catalysis19 citations Open access
Semantic Scholar
O-fucosylation of thrombospondin type 1 repeats is essential for ECM remodeling and signaling during bone development
Sanjiv Neupane, Steven J. Berardinelli, Daniel C Cameron, R. C. Grady +9 more
2022Matrix Biology17 citations Open access
Semantic Scholar
Modulation of the NOTCH1 Pathway by LUNATIC FRINGE Is Dominant over That of MANIC or RADICAL FRINGE
Florian Pennarubia, A. Nairn, Megumi Takeuchi, K. Moremen +1 more
2021Molecules15 citations Open access
Semantic Scholar
Cancer-associated Notch receptor variants lead to O-fucosylation defects that deregulate Notch signaling
Florian Pennarubia, Atsuko Ito, Megumi Takeuchi, R. Haltiwanger
2022Journal of Biological Chemistry9 citations Open access
Semantic Scholar
Disease modeling and gene correction of LGMDR21 iPSCs elucidates the role of POGLUT1 in skeletal muscle maintenance, regeneration, and the satellite cell niche
Jose L Ortiz-Vitali, Jian-Bo Wu, Nasa Y Xu, Annie W Shieh +8 more
2023Molecular Therapy: Nucleic Acids7 citations Open access
Semantic Scholar
Characterization of Ceramides and Glucosylceramides of the Satsuma Mandarin(Citrus unshiu) Fruit.
K. Mukai, Megumi Takeuchi, M. Ohnishi, Masatake Kudoh +1 more
2022Journal of Oleo Science4 citations Open access
Semantic Scholar
Corrigendum to: ADAMTS9 and ADAMTS20 are differentially affected by loss of B3GLCT in mouse model of Peters plus syndrome.
B. Holdener, C. Percival, R. C. Grady, Daniel C Cameron +14 more
2020Human Molecular Genetics1 citations Open access
Semantic Scholar
Lipopolysaccharide stimulation of RAW264.7 cells is a model for identifying novel clients of Hsc70
John F. Rakus, Nicholas R. Kegley, Alex J. Ashley, M. Parsons +1 more
2020bioRxiv1 citations Open access
Semantic Scholar
Identifying C‐Mannosylated Proteins in RAW264.7 Cells
Nicholas Ryan Kegley, Karli Boober, Atsuko Ito, Megumi Takeuchi +2 more
2019The FASEB Journal1 citations
Semantic Scholar

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