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Krzysztof Wrzesinski · SciRah

Researcher profile · Semantic Scholar

Krzysztof Wrzesinski

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Krzysztof Wrzesinski — researcher profile on SciRah

h-index: 17
Works: 43
Citations: 1,308

Most-cited papers

Proteome Analysis Reveals Phosphorylation of ATP Synthase β-Subunit in Human Skeletal Muscle and Proteins with Potential Roles in Type 2 Diabetes*
K. Højlund, Krzysztof Wrzesinski, P. Larsen, S. Fey +7 more
2003Journal of Biological Chemistry230 citations Open access
Semantic Scholar
Phosphoproteome Analysis of Functional Mitochondria Isolated from Resting Human Muscle Reveals Extensive Phosphorylation of Inner Membrane Protein Complexes and Enzymes*
Xiaolu Zhao, I. R. León, Steffen Bak, M. Mogensen +3 more
2010Molecular & Cellular Proteomics177 citations Open access
Semantic Scholar
University of Southern Denmark Determination of Drug Toxicity Using 3D Spheroids Constructed From an Immortal Human Hepatocyte Cell Line
Line, Fey, Krzysztof Wrzesinski
2012142 citations
Semantic Scholar
The Cultural Divide: Exponential Growth in Classical 2D and Metabolic Equilibrium in 3D Environments
Krzysztof Wrzesinski, A. Rogowska-Wrzesińska, Rattiyaporn Kanlaya, K. Borkowski +6 more
2014PLoS ONE72 citations Open access
Semantic Scholar
Effect of acid shock on protein expression by biofilm cells of Streptococcus mutans.
J. Welin, J. C. Wilkins, David Beighton, Krzysztof Wrzesinski +4 more
2003FEMS Microbiology Letters66 citations Open access
Semantic Scholar
HepG2/C3A 3D spheroids exhibit stable physiological functionality for at least 24 days after recovering from trypsinisation
Krzysztof Wrzesinski, M. Magnone, L. V. Hansen, M. Kruse +11 more
201358 citations Open access
Semantic Scholar
Determination of Drug Toxicity Using 3D Spheroids Constructed From an Immortal Human Hepatocyte Cell Line
Stephen J. Fey, Krzysztof Wrzesinski
2012Toxicological Sciences54 citations Open access
Semantic Scholar
Hepatocellular carcinoma (HepG2/C3A) cell-based 3D model for genotoxicity testing of chemicals.
Martina Štampar, Helle Sedighi Frandsen, A. Rogowska-Wrzesińska, Krzysztof Wrzesinski +2 more
2020Science of the Total Environment53 citations Open access
Semantic Scholar
Top-down and Middle-down Protein Analysis Reveals that Intact and Clipped Human Histones Differ in Post-translational Modification Patterns*
Andrey Tvardovskiy, Krzysztof Wrzesinski, Simone Sidoli, S. Fey +2 more
2015Molecular & Cellular Proteomics51 citations Open access
Semantic Scholar
From 2D to 3D--a New Dimension for Modelling the Effect of Natural Products on Human Tissue.
Krzysztof Wrzesinski, S. Fey
2015Current pharmaceutical design49 citations
Semantic Scholar
Metabolic Reprogramming and the Recovery of Physiological Functionality in 3D Cultures in Micro-Bioreactors
Krzysztof Wrzesinski, S. Fey
2018Bioengineering48 citations Open access
Semantic Scholar
Immune-mediated beta-cell destruction in vitro and in vivo-A pivotal role for galectin-3.
A. Karlsen, Zenia M. Størling, T. Sparre, M. Larsen +16 more
2006Biochemical and Biophysical Research Communications - BBRC39 citations
Semantic Scholar
Recent advances in three-dimensional cell culturing to assess liver function and dysfunction: from a drug biotransformation and toxicity perspective
Carlemi Calitz, J. Hamman, S. Fey, Krzysztof Wrzesinski +1 more
2018Toxicology Mechanisms and Methods31 citations
Semantic Scholar
Characterization of an Alginate Encapsulated LS180 Spheroid Model for Anti-colorectal Cancer Compound Screening.
Tanya Smit, Carlemi Calitz, C. Willers, H. Svitina +4 more
2020ACS Medicinal Chemistry Letters26 citations Open access
Semantic Scholar
Cell-free DNA in a three-dimensional spheroid cell culture model: A preliminary study.
J. Aucamp, Carlemi Calitz, A. Bronkhorst, Krzysztof Wrzesinski +3 more
2017International Journal of Biochemistry and Cell Biology21 citations Open access
Semantic Scholar
A sub-chronic Xysmalobium undulatum hepatotoxicity investigation in HepG2/C3A spheroid cultures compared to an in vivo model.
Carlemi Calitz, J. Hamman, S. Fey, A. Viljoen +2 more
2019Journal of Ethnopharmacology18 citations Open access
Semantic Scholar
Proteomics identifies molecular networks affected by tetradecylthioacetic acid and fish oil supplemented diets.
Krzysztof Wrzesinski, I. R. León, Katarzyna Kulej, R. Sprenger +5 more
2013Journal of Proteomics18 citations
Semantic Scholar
Anticancer Potential of Sutherlandia frutescens and Xysmalobium undulatum in LS180 Colorectal Cancer Mini-Tumors
Chrisna Gouws, Tanya Smit, C. Willers, H. Svitina +2 more
2021Molecules16 citations Open access
Semantic Scholar
Acetaminophen-induced S-nitrosylation and S-sulfenylation signalling in 3D cultured hepatocarcinoma cell spheroids
K. Wojdyla, Krzysztof Wrzesinski, J. Williamson, Stephen J. Fey +1 more
2016Toxicological Research16 citations Open access
Semantic Scholar
Increased reproducibility of brain organoids through controlled fluid dynamics
Giuseppe Aiello, M. Nemir, Barbora Vidimova, C. Ramel +4 more
2025bioRxiv14 citations Open access
Semantic Scholar
Clinostat 3D Cell Culture: Protocols for the Preparation and Functional Analysis of Highly Reproducible, Large, Uniform Spheroids and Organoids.
Krzysztof Wrzesinski, Helle Sedighi Frandsen, Carlemi Calitz, Chrisna Gouws +2 more
2021Methods in molecular biology13 citations
Semantic Scholar
Toxicity and anti-prolific properties of Xysmalobium undulatum water extract during short-term exposure to two-dimensional and three-dimensional spheroid cell cultures
Carlemi Calitz, J. Hamman, A. Viljoen, S. Fey +2 more
2018Toxicology Mechanisms and Methods12 citations Open access
Semantic Scholar
Mass spectrometry based approach for identification and characterisation of fluorescent proteins from marine organisms.
K. Wojdyla, A. Rogowska-Wrzesińska, Krzysztof Wrzesinski, P. Roepstorff
2011Journal of Proteomics11 citations
Semantic Scholar
A Novel NCI-H69AR Drug-Resistant Small-Cell Lung Cancer Mini-Tumor Model for Anti-Cancer Treatment Screening
Alandi van Niekerk, Krzysztof Wrzesinski, Dewald Steyn, Chrisna Gouws
2023Cells10 citations Open access
Semantic Scholar
Comparative proteome analysis of three mouse lung adenocarcinoma CMT cell lines with different metastatic potential by two‐dimensional gel electrophoresis and mass spectrometry
Kelan Zhang, Krzysztof Wrzesinski, J. F. Stephen, P. Larsen +2 more
2008Proteomics10 citations
Semantic Scholar
A novel NCI‐H69V small cell lung cancer functional mini‐tumor model for future treatment screening applications
Liezaan van der Merwe, H. Svitina, C. Willers, Krzysztof Wrzesinski +1 more
2022Biotechnology progress (Print)9 citations Open access
Semantic Scholar
A Purpose-Built System for Culturing Cells as In Vivo Mimetic 3D Structures
Krzysztof Wrzesinski, Søren Alnøe, H. H. Jochumsen, K. Mikkelsen +4 more
2021BioMechanics and Functional Tissue Engineering [Working Title]9 citations Open access
Semantic Scholar
Determination of Acute Lethal and Chronic Lethal Thresholds of Valproic Acid using 3D Spheroids Constructed from the Immortal Human Hepatocyte Cell Line Hepg2/C3A
S. Fey, Krzysztof Wrzesinski
20139 citations
Semantic Scholar
Assessing CMT cell line stability by two dimensional polyacrylamide gel electrophoresis and mass spectrometry based proteome analysis.
Kelan Zhang, Krzysztof Wrzesinski, S. Fey, P. Mose-Larsen +2 more
2008Journal of Proteomics8 citations
Semantic Scholar
Response to and recovery from treatment in human liver-mimetic clinostat spheroids: a model for assessing repeated-dose drug toxicity
S. Fey, B. Korzeniowska, Krzysztof Wrzesinski
2020Toxicological Research7 citations Open access
Semantic Scholar
Heteromer score—using internal standards to assess the quality of proteomic data
A. Rogowska-Wrzesińska, Krzysztof Wrzesinski, Stephen J. Fey
2014Proteomics6 citations
Semantic Scholar
After trypsinisation, 3D spheroids of C3A hepatocytes need 18 days to re-establish similar levels of key physiological functions to those seen in the liver
Krzysztof Wrzesinski, Stephen J. Fey
20134 citations Open access
Semantic Scholar
Microgravity spheroids as a reliable, long-term tool for predictive toxicology
S. Fey, Krzysztof Wrzesinski
20133 citations
Semantic Scholar
P-49 - The role of reversible cysteine oxidations in intracellular signaling – mass spectrometry based study of acetaminophen driven redox imbalance
A. Rogowska-Wrzesińska, Krzysztof Wrzesinski, K. Wojdyla, J. Williamson +1 more
20161 citations
Semantic Scholar
Active 3D environment: A key to stable, reproducible, mimetic tissues
Krzysztof Wrzesinski
20180 citations Open access
Semantic Scholar
University of Southern Denmark HepG 2 / C 3 A 3 D spheroids exhibit stable physiological functionality for at least 24 days after recovering from trypsination
Krzysztof Wrzesinski, M. Magnone, L. V. Hansen, M. Kruse +10 more
20130 citations
Semantic Scholar
Syddansk Universitet HepG 2 / C 3 A 3 D spheroids exhibit stable physiological functionality for at least 24 days after recovering from trypsination
Krzysztof Wrzesinski, M. Magnone, L. V. Hansen, M. Kruse +10 more
20130 citations
Semantic Scholar
Syddansk Universitet Determination of Drug Toxicity Using 3 D Spheroids Constructed From an Immortal Human Hepatocyte Cell
Fey, Krzysztof Wrzesinski
20120 citations
Semantic Scholar
Recovery of important physiological functions in 3D culture of immortal hepatocytes
Krzysztof Wrzesinski, S. Fey
20110 citations
Semantic Scholar
The Search for Novel Fluorescent Proteins in Marine Organisms
K. Wojdyla, A. Rogowska-Wrzesińska, Krzysztof Wrzesinski, N. Bache +5 more
20100 citations
Semantic Scholar
Proteome Analysis of Mouse Long Cancer CMT Cell Lines
Kelan Zhang, Krzysztof Wrzesinski, S. Fey, P. Larsen +1 more
20080 citations
Semantic Scholar
ID: 203 The Effects of Oral Contraceptives on Plasma - Studied by Proteomics.
Krzysztof Wrzesinski, J. Jespersen, H. Vorum, S. Fey +4 more
20060 citations
Semantic Scholar
Diagnosing or determining predisposition of a disease relating to diabetes in a human, by measuring level of a protein e.g. ATP synthase (-subunit, phosphoglucomutase 1, in biological sample: Publication documents
K. Højlund, Stephen J. Fey, P. Larsen, H. Beck-Nielsen +1 more
20030 citations
Semantic Scholar

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