M. Breyer

Most-cited papers

Sirt1 activation protects the mouse renal medulla from oxidative injury.
Wenjuan He, Ying-Ying Wang, Ming-Zhi Zhang, Li You +8 more
2010Journal of Clinical Investigation309 citations Open access
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Mouse Models of Diabetic Nephropathy
F. C. Brosius, C. Alpers, Erwin P. Bottinger, M. Breyer +13 more
2009Journal of the American Society of Nephrology283 citations Open access
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THE NEXT GENERATION OF THERAPEUTICS FOR CHRONIC KIDNEY DISEASE
M. Breyer, K. Suszták
2016Nature reviews. Drug discovery265 citations Open access
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Mapping the Single Cell Transcriptomic Response of Murine Diabetic Kidney Disease to Therapies
Haojia Wu, Romer Gonzalez Villalobos, Xiang Yao, Dermot Reilly +5 more
2022Cell Metabolism222 citations Open access
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Reduction of renal superoxide dismutase in progressive diabetic nephropathy.
H. Fujita, H. Fujishima, S. Chida, Keiko Takahashi +6 more
2009Journal of the American Society of Nephrology181 citations Open access
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Circulating αKlotho influences phosphate handling by controlling FGF23 production.
Rosamund C. Smith, L. O'Bryan, Emily G. Farrow, Lelia J. Summers +15 more
2012Journal of Clinical Investigation146 citations Open access
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Prostaglandin E2-Mediated Attenuation of Mesocortical Dopaminergic Pathway Is Critical for Susceptibility to Repeated Social Defeat Stress in Mice
Kohei Tanaka, T. Furuyashiki, S. Kitaoka, Y. Senzai +6 more
2012Journal of Neuroscience128 citations Open access
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Markers of early progressive renal decline in Type 2 diabetes suggest different implications for etiological studies and prognostic tests development
N. Nowak, J. Skupień, A. Smiles, M. Yamanouchi +7 more
2018Kidney International112 citations Open access
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A prospective study of multiple protein biomarkers to predict progression in diabetic chronic kidney disease.
R. Agarwal, K. Duffin, D. Laska, J. Voelker +2 more
2014Nephrology, Dialysis and Transplantation72 citations Open access
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Prostaglandin-dependent modulation of dopaminergic neurotransmission elicits inflammation-induced aversion in mice.
Michael Fritz, A. Klawonn, Anna Nilsson, A. Singh +17 more
2016Journal of Clinical Investigation69 citations Open access
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Developing Treatments for Chronic Kidney Disease in the 21st Century
M. Breyer, K. Suszták
2016Seminars in Nephrology61 citations Open access
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A maladaptive role for EP4 receptors in podocytes.
Erin M Stitt-Cavanagh, Wissam H. Faour, Kaede Takami, Anthony J. Carter +5 more
2010Journal of the American Society of Nephrology61 citations Open access
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Inactivation of the EP3 receptor attenuates the Angiotensin II pressor response via decreasing arterial contractility
Li-Hong Chen, Yifei Miao, Yahua Zhang, D. Dou +14 more
2012Arteriosclerosis, Thrombosis and Vascular Biology54 citations Open access
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Better nephrology for mice--and man.
M. Breyer, Z. Qi
2010Kidney International50 citations Open access
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Targeting VE-PTP phosphatase protects the kidney from diabetic injury
Isabel A Carota, Yael Kenig-Kozlovsky, T. Onay, Rizaldy P. Scott +15 more
2019Journal of Experimental Medicine48 citations Open access
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Aberrant bispecific antibody pharmacokinetics linked to liver sinusoidal endothelium clearance mechanism in cynomolgus monkeys
A. Datta-Mannan, Johnny E. Croy, L. Schirtzinger, Stacy Torgerson +2 more
2016mAbs48 citations Open access
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EP1−/− Mice Have Enhanced Osteoblast Differentiation and Accelerated Fracture Repair
Min-Jie Zhang, H. Ho, T. Sheu, M. Breyer +5 more
2010Journal of Bone and Mineral Research46 citations Open access
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Improved clinical trial enrollment criterion to identify patients with diabetes at risk of end stage renal disease
M. Yamanouchi, J. Skupień, M. Niewczas, A. Smiles +9 more
2017Kidney International45 citations Open access
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Profibrotic Circulating Proteins and Risk of Early Progressive Renal Decline in Patients With Type 2 Diabetes With and Without Albuminuria
Katsuhito Ihara, J. Skupień, Hiroki Kobayashi, Zaipul I. Md Dom +8 more
2020Diabetes Care38 citations Open access
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SOD1, but not SOD3, deficiency accelerates diabetic renal injury in C57BL/6-Ins2Akita diabetic mice
H. Fujita, H. Fujishima, Keiko Takahashi, Takehiro Sato +9 more
2012Metabolism: Clinical and Experimental38 citations Open access
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Unbiased kidney-centric molecular categorization of chronic kidney disease as a step towards precision medicine
A. Reznichenko, V. Nair, S. Eddy, D. Fermin +20 more
2024Kidney International36 citations Open access
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Progressive Renal Disease Established by Renin-Coding Adeno-Associated Virus-Driven Hypertension in Diverse Diabetic Models.
Shannon M. Harlan, K. Heinz-Taheny, J. Sullivan, T. Wei +7 more
2017Journal of the American Society of Nephrology34 citations Open access
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Role of TGF-alpha in the progression of diabetic kidney disease.
Josef G. Heuer, Shannon M. Harlan, Derek D. Yang, Dianna L Jaqua +8 more
2017AJP - Renal Physiology32 citations
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Overcoming Barriers in Kidney Health-Forging a Platform for Innovation.
P. Linde, P. Archdeacon, M. Breyer, T. Ibrahim +11 more
2016Journal of the American Society of Nephrology29 citations Open access
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Measurement of glomerular filtration rate in conscious mice.
Z. Qi, M. Breyer
2009Methods in molecular biology26 citations
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Generation of a Tenascin-C-CreER2 Knockin Mouse Line for Conditional DNA Recombination in Renal Medullary Interstitial Cells
Wenjuan He, Qiong-Hong Xie, Ying-Ying Wang, Jing Chen +5 more
2013PLoS ONE25 citations Open access
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Novel avenues for drug discovery in diabetic kidney disease
M. Breyer, M. Kretzler
2018Expert Opinion on Drug Discovery22 citations
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Effects of global or targeted deletion of the EP4 receptor on the response of osteoblasts to prostaglandin in vitro and on bone histomorphometry in aged mice.
Q. Gao, Peili Zhan, C. Alander, B. Kream +4 more
2009Bone21 citations
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Enhanced pressor response to acute angiotensin II infusion in mice lacking membrane-associated prostaglandin E2 synthase-1
Dong-juan Zhang, Li-Hong Chen, Yahua Zhang, Guang-rui Yang +9 more
2010Acta Pharmacologica Sinica18 citations Open access
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Increased Dietary Sodium Induces COX2 Expression by activating NFκB in Renal Medullary Interstitial Cells
Wenjuan He, Min Zhang, Min Zhao, L. Davis +4 more
2013Pflügers Archiv: European Journal of Physiology17 citations Open access
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Viral transduction of renin rapidly establishes persistent hypertension in diverse murine strains.
Shannon M. Harlan, Robert A. Ostroski, T. Coskun, L. D. Yantis +2 more
2015American Journal of Physiology. Regulatory Integrative and Comparative Physiology15 citations
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Cyclooxygenase-2 contributes to diabetic nephropathy through glomerular EP4 receptor.
Yi Guan, L. Davis, M. Breyer, Chuan-Ming Hao
2022Prostaglandins & other lipid mediators14 citations
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Generation and Activity of a Humanized Monoclonal Antibody That Selectively Neutralizes the Epidermal Growth Factor Receptor Ligands Transforming Growth Factor-α and Epiregulin
C. Beidler, R. Petrovan, E. Conner, J. Boyles +10 more
2014Journal of Pharmacology and Experimental Therapeutics14 citations
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Nonselective Cyclooxygenase Inhibition Retards Cyst Progression in a Murine Model of Autosomal Dominant Polycystic Kidney Disease
Min Zhang, M. Srichai, Min Zhao, Jian Chen +4 more
2019International Journal of Medical Sciences12 citations Open access
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Improving productivity of modern-day drug discovery
M. Breyer
2014Expert Opinion on Drug Discovery12 citations Open access
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Drug discovery for diabetic nephropathy: trying the leap from mouse to man.
M. Breyer
2012Seminars in Nephrology12 citations
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From bench to patient: model systems in drug discovery
M. Breyer, A. Look, Alessandra Cifra
2015Disease Models & Mechanisms11 citations Open access
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Arachidonic Acid Metabolites and the Kidney
Raymond C. Harris, M. Breyer, R. Breyer
201111 citations
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Mitochondrial and NAD+ metabolism predict recovery from acute kidney injury in a diverse mouse population
Jean-David Morel, Maroun Bou Sleiman, T. Y. Li, Giacomo V. G. von Alvensleben +12 more
2023JCI Insight9 citations Open access
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Pathological and Transcriptome Changes in the ReninAAV db/db uNx Model of Advanced Diabetic Kidney Disease Exhibit Features of Human Disease
Shannon M. Harlan, K. Heinz-Taheny, Jessica M. Overstreet, M. Breyer +2 more
2018Toxicologic pathology (Print)9 citations Open access
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Diabetic nephropathy: a national dialogue.
M. Breyer, T. Coffman, M. Flessner, L. Fried +6 more
2013American Society of Nephrology. Clinical Journal9 citations Open access
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Generation of a Conditional Allele for the Mouse Endothelial Nitric Oxide Synthase Gene
Rosie Jiang, Su-Wan Wang, Keiko Takahashi, H. Fujita +4 more
2012Genesis9 citations Open access
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Osteopontin in diabetic nephropathy: signpost or road?
Josef G. Heuer, M. Breyer
2010Kidney International9 citations Open access
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The Use of Genomics To Drive Kidney Disease Drug Discovery and Development.
D. Reilly, M. Breyer
2020American Society of Nephrology. Clinical Journal8 citations Open access
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Vascular Endothelial Growth Factors and Risk of Cardio-renal Events: Results from the CREDENCE trial.
J. Januzzi, Yuxi Liu, N. Sattar, Yshai Yavin +7 more
2024American Heart Journal5 citations Open access
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Prostacyclin Mitigates Renal Fibrosis by Activating Fibroblast Prostaglandin I2 Receptor
Jing Li, Yi Guan, Yun-Yu Xu, Yi-Jun Cao +5 more
2023Journal of the American Society of Nephrology4 citations Open access
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Progress in progression?
M. Breyer
2010Journal of the American Society of Nephrology4 citations
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Kynurenines and Change in Body Mass Index in Autosomal Dominant Polycystic Kidney Disease
Alex R. Dinh, Victor Dishy, Jason R. Waggoner, Dénes Csonka +8 more
2023Journal of the American Society of Nephrology3 citations
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Tackling AKI.
R. Rana, M. Breyer
2023Journal of the American Society of Nephrology3 citations Open access
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Translating experimental diabetic nephropathy studies from mice to men.
M. Breyer
2011Contributions to Nephrology3 citations
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