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M. Schweiger · SciRah

Researcher profile · Semantic Scholar

M. Schweiger

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M. Schweiger — researcher profile on SciRah

h-index: 36
Works: 99
Citations: 4,476

Most-cited papers

Telomerase activation by genomic rearrangements in high-risk neuroblastoma
M. Peifer, F. Hertwig, F. Roels, D. Dreidax +51 more
2015Nature547 citations Open access
Semantic Scholar
Identity-by-descent filtering of exome sequence data identifies PIGV mutations in hyperphosphatasia mental retardation syndrome
P. Krawitz, M. Schweiger, C. Rödelsperger, C. Marcelis +25 more
2010Nature Genetics321 citations Open access
Semantic Scholar
Effective diagnosis of genetic disease by computational phenotype analysis of the disease-associated genome
T. Żemojtel, S. Köhler, Luisa Mackenroth, Marten Jäger +21 more
2014Science Translational Medicine252 citations Open access
Semantic Scholar
Somatic Mutation Profiles of MSI and MSS Colorectal Cancer Identified by Whole Exome Next Generation Sequencing and Bioinformatics Analysis
B. Timmermann, M. Kerick, Christina Roehr, A. Fischer +16 more
2010PLoS ONE234 citations Open access
Semantic Scholar
Targeted high throughput sequencing in clinical cancer Settings: formaldehyde fixed-paraffin embedded (FFPE) tumor tissues, input amount and tumor heterogeneity
M. Kerick, Melanie Isau, B. Timmermann, H. Sültmann +8 more
2011BMC Medical Genomics190 citations Open access
Semantic Scholar
Genome-Wide Massively Parallel Sequencing of Formaldehyde Fixed-Paraffin Embedded (FFPE) Tumor Tissues for Copy-Number- and Mutation-Analysis
M. Schweiger, M. Kerick, B. Timmermann, M. Albrecht +4 more
2009PLoS ONE173 citations Open access
Semantic Scholar
The Pentose Phosphate Pathway Is a Metabolic Redox Sensor and Regulates Transcription During the Antioxidant Response
Antje Krüger, Nana-Maria Grüning, M. Wamelink, M. Kerick +8 more
2011Antioxidants and Redox Signaling167 citations
Semantic Scholar
Bromodomain Protein 4 Mediates the Papillomavirus E2 Transcriptional Activation Function
M. Schweiger, Jian-Xin You, P. Howley
2006Journal of Virology152 citations
Semantic Scholar
DNA methylation in adenovirus, adenovirus-transformed cells, and host cells.
U. Günthert, M. Schweiger, M. Stupp, W. Doerfler
1976Proceedings of the National Academy of Sciences of the United States of America142 citations Open access
Semantic Scholar
Genome-wide DNA methylation events in TMPRSS2-ERG fusion-negative prostate cancers implicate an EZH2-dependent mechanism with miR-26a hypermethylation.
Stefan T. Börno, A. Fischer, M. Kerick, Maria Fälth +21 more
2012Cancer Discovery134 citations
Semantic Scholar
The Interlaboratory RObustness of Next-generation sequencing (IRON) study: a deep sequencing investigation of TET2, CBL and KRAS mutations by an international consortium involving 10 laboratories
A. Kohlmann, Hans-Ulrich Klein, S. Weissmann, S. Bresolin +20 more
2011Leukemia116 citations Open access
Semantic Scholar
The bromodomain protein BRD4 regulates the KEAP1/NRF2-dependent oxidative stress response
M. Hussong, Stefan T. Börno, M. Kerick, A. Wunderlich +6 more
2014Cell Death and Disease111 citations Open access
Semantic Scholar
Deregulation and epigenetic modification of BCL2-family genes cause resistance to venetoclax in hematologic malignancies
D. Thomalla, L. Beckmann, C. Grimm, M. Oliverio +33 more
2022Blood95 citations Open access
Semantic Scholar
Brd4-Independent Transcriptional Repression Function of the Papillomavirus E2 Proteins
M. Schweiger, Matthias Ottinger, Jian-Xin You, P. Howley
2007Journal of Virology83 citations Open access
Semantic Scholar
miR-22 and miR-29a Are Members of the Androgen Receptor Cistrome Modulating LAMC1 and Mcl-1 in Prostate Cancer.
L. Pasqualini, Huajie Bu, M. Puhr, N. Narisu +9 more
2015Molecular Endocrinology76 citations Open access
Semantic Scholar
Inhibition of E2 Binding to Brd4 Enhances Viral Genome Loss and Phenotypic Reversion of Bovine Papillomavirus-Transformed Cells
Jian-Xin You, M. Schweiger, P. Howley
2005Journal of Virology71 citations Open access
Semantic Scholar
A cancer specific hypermethylation signature of the TERT promoter predicts biochemical relapse in prostate cancer: a retrospective cohort study
P. Castelo-Branco, R. Leão, T. Lipman, B. Campbell +19 more
2016OncoTarget68 citations Open access
Semantic Scholar
The power of NGS technologies to delineate the genome organization in cancer: from mutations to structural variations and epigenetic alterations
M. Schweiger, M. Kerick, B. Timmermann, Melanie Isau
2011Cancer Metastasis Review68 citations
Semantic Scholar
Low-level APC mutational mosaicism is the underlying cause in a substantial fraction of unexplained colorectal adenomatous polyposis cases
I. Spier, D. Drichel, M. Kerick, J. Kirfel +16 more
2015Journal of Medical Genetics67 citations Open access
Semantic Scholar
The bromodomain protein BRD4 regulates splicing during heat shock
M. Hussong, C. Kaehler, M. Kerick, Christina Grimm +7 more
2016Nucleic Acids Research63 citations Open access
Semantic Scholar
High-Throughput miRNA and mRNA Sequencing of Paired Colorectal Normal, Tumor and Metastasis Tissues and Bioinformatic Modeling of miRNA-1 Therapeutic Applications
Christina Röhr, M. Kerick, A. Fischer, Alexander Kühn +18 more
2013PLoS ONE63 citations Open access
Semantic Scholar
Brd4 Regulation of Papillomavirus Protein E2 Stability
Gang Zheng, M. Schweiger, Gustavo Martinez-Noel, Leon Zheng +3 more
2009Journal of Virology60 citations Open access
Semantic Scholar
Campylobacter jejuni impairs sodium transport and epithelial barrier function via cytokine release in human colon
R. Bücker, S. Krug, V. Moos, C. Bojarski +10 more
2017Mucosal Immunology58 citations Open access
Semantic Scholar
QSEA—modelling of genome-wide DNA methylation from sequencing enrichment experiments
M. Lienhard, Sabrina Grasse, J. Rolff, S. Frese +10 more
2016Nucleic Acids Research58 citations Open access
Semantic Scholar
Exome sequencing identifies potential novel candidate genes in patients with unexplained colorectal adenomatous polyposis
I. Spier, M. Kerick, D. Drichel, S. Horpaopan +16 more
2016Familial Cancer54 citations Open access
Semantic Scholar
Genomic and transcriptomic heterogeneity of colorectal tumours arising in Lynch syndrome
H. Binder, L. Hopp, M. Schweiger, S. Hoffmann +30 more
2017Journal of Pathology52 citations Open access
Semantic Scholar
Hsp90 inhibition differentially destabilises MAP kinase and TGF-beta signalling components in cancer cells revealed by kinase-targeted chemoproteomics
A. Haupt, G. Joberty, M. Bantscheff, H. Fröhlich +11 more
2012BMC Cancer52 citations Open access
Semantic Scholar
Anterior gradient 2 and 3 – two prototype androgen‐responsive genes transcriptionally upregulated by androgens and by oestrogens in prostate cancer cells
Huajie Bu, M. Schweiger, T. Manke, A. Wunderlich +7 more
2013The FEBS Journal49 citations
Semantic Scholar
DNA–Methylome Analysis of Mouse Intestinal Adenoma Identifies a Tumour-Specific Signature That Is Partly Conserved in Human Colon Cancer
Christina Grimm, L. Chavez, M. Vilardell, A. Farrall +12 more
2013PLoS Genetics49 citations Open access
Semantic Scholar
Epigenomic profiling of non-small cell lung cancer xenografts uncover LRP12 DNA methylation as predictive biomarker for carboplatin resistance
Sabrina Grasse, M. Lienhard, S. Frese, M. Kerick +22 more
2018Genome Medicine47 citations Open access
Semantic Scholar
Genomics and epigenomics of colorectal cancer
M. Schweiger, M. Hussong, Christina Röhr, H. Lehrach
2013Wiley Interdisciplinary Reviews: Systems Biology and Medicine45 citations
Semantic Scholar
Rare Noncoding Mutations Extend the Mutational Spectrum in the PGAP3 Subtype of Hyperphosphatasia with Mental Retardation Syndrome
A. Knaus, Tomonari Awaya, I. Helbig, Z. Afawi +15 more
2016Human Mutation44 citations Open access
Semantic Scholar
Epithelial barrier dysfunction in lymphocytic colitis through cytokine-dependent internalization of claudin-5 and -8
C. Barmeyer, I. Erko, Karem Awad, A. Fromm +8 more
2017Journal of gastroenterology43 citations
Semantic Scholar
Putative Prostate Cancer Risk SNP in an Androgen Receptor‐Binding Site of the Melanophilin Gene Illustrates Enrichment of Risk SNPs in Androgen Receptor Target Sites
Huajie Bu, N. Narisu, B. Schlick, Johannes Rainer +7 more
2015Human Mutation42 citations Open access
Semantic Scholar
A hormone-dependent feedback-loop controls androgen receptor levels by limiting MID1, a novel translation enhancer and promoter of oncogenic signaling
Andrea Köhler, Ümmühan Demir, Eva Kickstein, S. Krauß +11 more
2014Molecular Cancer40 citations Open access
Semantic Scholar
The KRAB-containing zinc-finger transcriptional regulator ZBRK1 activates SCA2 gene transcription through direct interaction with its gene product, ataxin-2.
L. Hallen, H. Klein, C. Stoschek, S. Wehrmeyer +10 more
2011Human Molecular Genetics40 citations Open access
Semantic Scholar
Identity-by-descent filtering of exome sequence data for disease–gene identification in autosomal recessive disorders
C. Rödelsperger, P. Krawitz, S. Bauer, Jochen Hecht +5 more
2011Bioinform.36 citations Open access
Semantic Scholar
Correlation between genomic index lesions and mpMRI and 68Ga-PSMA-PET/CT imaging features in primary prostate cancer
C. Kesch, J. Radtke, Axel Wintsche, M. Wiesenfarth +33 more
2018Scientific Reports34 citations Open access
Semantic Scholar
Claudin-10a Deficiency Shifts Proximal Tubular Cl- Permeability to Cation Selectivity via Claudin-2 Redistribution
T. Breiderhoff, N. Himmerkus, Luca Meoli, A. Fromm +20 more
2022Journal of the American Society of Nephrology31 citations Open access
Semantic Scholar
ERG Induces Epigenetic Activation of Tudor Domain-Containing Protein 1 (TDRD1) in ERG Rearrangement-Positive Prostate Cancer
L. Kacprzyk, M. Laible, Tatjana Andrasiuk, J. C. Brase +6 more
2013PLoS ONE31 citations Open access
Semantic Scholar
Epigenetic Drifts during Long-Term Intestinal Organoid Culture
T. Thalheim, Susann Siebert, Marianne Quaas, M. Herberg +3 more
2021Cells30 citations Open access
Semantic Scholar
Impaired Intestinal Permeability of Tricellular Tight Junctions in Patients with Irritable Bowel Syndrome with Mixed Bowel Habits (IBS-M)
Karem Awad, C. Barmeyer, C. Bojarski, Oliver Nagel +4 more
2023Cells28 citations Open access
Semantic Scholar
The intron-enriched HERV-K(HML-10) family suppresses apoptosis, an indicator of malignant transformation
F. Broecker, R. Horton, J. Heinrich, A. Franz +3 more
2016Mobile DNA26 citations Open access
Semantic Scholar
Cell type specific transcriptional activities among different papillomavirus long control regions and their regulation by E2
Matthias Ottinger, Jennifer A. Smith, M. Schweiger, D. Robbins +3 more
2009Virology26 citations Open access
Semantic Scholar
Impact of Acute Aerobic Exercise on Genome-Wide DNA-Methylation in Natural Killer Cells—A Pilot Study
A. Schenk, Christina Koliamitra, C. Bauer, R. Schier +3 more
2019Genes23 citations Open access
Semantic Scholar
ENaC Dysregulation Through Activation of MEK1/2 Contributes to Impaired Na+ Absorption in Lymphocytic Colitis
C. Barmeyer, I. Erko, A. Fromm, C. Bojarski +7 more
2016Inflammatory Bowel Diseases21 citations
Semantic Scholar
Loss of Msh2 and a single-radiation hit induce common, genome-wide, and persistent epigenetic changes in the intestine
M. Herberg, Susann Siebert, Marianne Quaas, T. Thalheim +7 more
2019Clinical Epigenetics20 citations Open access
Semantic Scholar
Genomics and epigenomics: new promises of personalized medicine for cancer patients.
M. Schweiger, C. Barmeyer, B. Timmermann
2013Briefings in Functional Genomics20 citations Open access
Semantic Scholar
Campylobacter concisus Impairs Sodium Absorption in Colonic Epithelium via ENaC Dysfunction and Claudin-8 Disruption
P. K. Nattramilarasu, R. Bücker, Fábia Daniela Lobo de Sá, A. Fromm +12 more
2020International Journal of Molecular Sciences19 citations Open access
Semantic Scholar
Co-inhibition of BET proteins and PI3Kα triggers mitochondrial apoptosis in rhabdomyosarcoma cells
Cathinka Boedicker, M. Hussong, Christina Grimm, N. Dolgikh +6 more
2020Oncogene17 citations
Semantic Scholar

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