M. Landray

Most-cited papers

1. Empagliflozin in Patients with Chronic Kidney Disease

   W. Herrington, N. Staplin, C. Wanner, J. B. Green +35 more

   2022New England Journal of Medicine1,521 citations Open access

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2. Impact of Diabetes on The Effects Of Sodium Glucose Co-Transporter-2 (SGLT2) Inhibitors on Kidney Outcomes: Collaborative Meta-Analysis of Large Placebo-Controlled Trials

   C. Baigent, J. Emberson, R. Haynes, W. Herrington +34 more

   2022The Lancet576 citations Open access

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3. Casirivimab and imdevimab in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial

   P. Horby, M. Mafham, L. Peto, M. Campbell +30 more

   2021medRxiv446 citations Open access

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4. Convalescent plasma in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial

   P. Horby, L. Estcourt, L. Peto, J. Emberson +33 more

   2021medRxiv427 citations Open access

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5. Azithromycin in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial

   Eugenia Mustafa Sadia Alfie Ashraf Sherif Mohamed Basir Al Abaleke Abbas Abbasi Abbott Abdelaziz Abdelbadiee , E. Abaleke, M. Abbas, Sadia Abbasi +496 more

   2021The Lancet289 citations Open access

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6. Impact of the COVID-19 pandemic on the detection and management of colorectal cancer in England: a population-based study

   E. Morris, R. Goldacre, E. Spata, M. Mafham +17 more

   2021The Lancet Gastroenterology and Hepatology270 citations Open access

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7. Baricitinib in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial and updated meta-analysis

   P. Horby, J. Emberson, M. Mafham, M. Campbell +29 more

   2022medRxiv269 citations Open access

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8. Effect of statin therapy on muscle symptoms: an individual participant data meta-analysis of large-scale, randomised, double-blind trials

   M. Blazing, E. Braunwald, J. A. de Lemos, S. Murphy +106 more

   2022The Lancet218 citations Open access

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9. A meta-analysis of GFR slope as a surrogate endpoint for kidney failure

   L. Inker, Willem H. Collier, Tom H. Greene, Shi-Yuan Miao +80 more

   2023Nature Medicine146 citations Open access

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10. Effects of statin therapy on diagnoses of new-onset diabetes and worsening glycaemia in large-scale randomised blinded statin trials: an individual participant data meta-analysis

    C. Reith, David Preiss, L. Blackwell, J. Emberson +128 more

    2024The Lancet Diabetes and Endocrinology108 citations Open access

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11. Higher dose corticosteroids in patients admitted to hospital with COVID-19 who are hypoxic but not requiring ventilatory support (RECOVERY): a randomised, controlled, open-label, platform trial

    O. A. F. J. K. M. S. H. A. Abani Abbas Abbas Abbas Abbas Abbas Abbasi Abbass, O. Abani, A. Abbas, F. Abbas +496 more

    2023The Lancet103 citations Open access

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12. The Integration of Clinical Trials with the Practice of Medicine: Repairing a House Divided

    Derek C. Angus, Alison J. Huang, Roger J. Lewis, Amy P. Abernethy +4 more

    2024Journal of the American Medical Association (JAMA)76 citations Open access

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13. Long-Term Effects of Empagliflozin in Patients with Chronic Kidney Disease

    W. Herrington, N. Staplin, N. Agrawal, C. Wanner +36 more

    2024New England Journal of Medicine74 citations Open access

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14. Design, recruitment, and baseline characteristics of the EMPA-KIDNEY trial

    William G. Christoph Jennifer B. Sibylle J. Parminder Kait Herrington Wanner Green Hauske Judge Mayne Ng Samm, W. Herrington, C. Wanner, J. Green +38 more

    2022Nephrology, Dialysis and Transplantation62 citations Open access

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15. The potential for improving cardio-renal outcomes in chronic kidney disease with the aldosterone synthase inhibitor vicadrostat (BI 690517): a rationale for the EASi-KIDNEY trial

    P. Judge, Katherine R. Tuttle, N. Staplin, S. Hauske +17 more

    2024Nephrology, Dialysis and Transplantation61 citations Open access

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16. Potential health and economic impacts of dexamethasone treatment for patients with COVID-19

    R. Águas, Adam Mahdi, R. Shretta, P. Horby +83 more

    2021Nature Communications60 citations Open access

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17. A Pragmatic Randomized Feasibility Trial of Influenza Vaccines.

    N. Johansen, D. Modin, J. Nealon, S. Samson +16 more

    2023NEJM Evidence49 citations Open access

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18. Casirivimab and imdevimab in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial

    Obbina Ali Fatima Mustafa Sadia Hakam Alfie Nabeel Ashraf Abani Abbas Abbas Abbas Abbasi Abbass Abbott Abdal, O. Abani, A. Abbas, F. Abbas +496 more

    2022The Lancet45 citations Open access

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19. High-Dose Influenza Vaccine Effectiveness against Hospitalization in Older Adults.

    N. Johansen, D. Modin, M. Loiacono, R. Harris +34 more

    2025New England Journal of Medicine44 citations

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20. Effects of Empagliflozin on Fluid Overload, Weight and Blood Pressure in Chronic Kidney Disease

    Kaitlin J. Mayne, N. Staplin, David F Keane, C. Wanner +26 more

    2023Journal of the American Society of Nephrology42 citations Open access

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21. Realising the full potential of data-enabled trials in the UK: a call for action

    M. Sydes, Y. Barbáchano, L. Bowman, T. Denwood +24 more

    2021BMJ Open41 citations Open access

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22. Assessment of adverse effects attributed to statin therapy in product labels: a meta-analysis of double-blind randomised controlled trials

    C. Reith, L. Blackwell, J. Emberson, D. Preiss +131 more

    2026The Lancet28 citations Open access

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23. Immunomodulatory therapy in children with paediatric inflammatory multisystem syndrome temporally associated with SARS-CoV-2 (PIMS-TS, MIS-C; RECOVERY): a randomised, controlled, open-label, platform trial.

    Saul N. Faust, R. Haynes, C. Jones, N. Staplin +496 more

    2024The Lancet Child & Adolescent Health28 citations Open access

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24. Determining the Relationship between Blood Pressure, Kidney Function, and Chronic Kidney Disease: Insights from Genetic Epidemiology

    N. Staplin, W. Herrington, F. Murgia, M. Ibrahim +10 more

    2022HYPERTENSION26 citations Open access

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25. Impact of new cardiovascular events on quality of life and hospital costs in people with cardiovascular disease in the UK and US

    J. N. Lui, C. Williams, Mi-Jun Keng, J. Hopewell +6 more

    2023Journal of the American Heart Association : Cardiovascular and Cerebrovascular Disease24 citations Open access

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26. Comparison of the Accuracy and Completeness of Records of Serious Vascular Events in Routinely Collected Data vs Clinical Trial–Adjudicated Direct Follow-up Data in the UK

    C. Harper, M. Mafham, W. Herrington, N. Staplin +7 more

    2021JAMA Network Open22 citations Open access

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27. Feasibility of randomizing Danish citizens aged 65–79 years to high-dose quadrivalent influenza vaccine vs. standard-dose quadrivalent influenza vaccine in a pragmatic registry-based setting: rationale and design of the DANFLU-1 Trial

    N. Johansen, D. Modin, J. Nealon, S. Samson +13 more

    2022Pilot and Feasibility Studies21 citations Open access

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28. Empagliflozin lowers serum uric acid in chronic kidney disease: exploratory analyses from the EMPA-KIDNEY trial

    Kaitlin J. Mayne, R. Sardell, N. Staplin, P. Judge +14 more

    2024Nephrology, Dialysis and Transplantation20 citations Open access

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29. Effectiveness of high-dose vs. standard-dose quadrivalent influenza vaccine against recurrent hospitalisations and mortality in relation to influenza circulation: a post-hoc analysis of the DANFLU-1 randomised clinical trial.

    N. Johansen, D. Modin, K. Skaarup, J. Nealon +18 more

    2024Clinical Microbiology and Infection20 citations Open access

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30. Establishing COVID-19 trials at scale and pace: Experience from the RECOVERY trial

    L. Peto, P. Horby, M. Landray

    2022Advances in Biological Regulation20 citations Open access

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31. High-Dose vs Standard-Dose Influenza Vaccine and Cardiovascular Outcomes in Older Adults

    N. Johansen, D. Modin, M. Loiacono, R. Harris +33 more

    2025JAMA cardiology17 citations Open access

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32. Data provenance and integrity of health-care systems data for clinical trials

    M. Murray, Sharon B. Love, James R. Carpenter, S. Hartley +5 more

    2022The Lancet Digital Health17 citations Open access

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33. Empagliflozin in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial

    P. Horby, N. Staplin, L. Peto, J. Emberson +36 more

    2023medRxiv16 citations Open access

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34. Long-term safety and efficacy of anacetrapib in patients with atherosclerotic vascular disease

    E. Sammons, J. Hopewell, F. Chen, W. Stevens +44 more

    2021European Heart Journal16 citations Open access

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35. A Pragmatic Individually Randomized Trial to Evaluate the Effectiveness of High-Dose vs. Standard-Dose Influenza Vaccine in Older Adults: Rationale and Design of the DANFLU-2 Trial.

    N. Johansen, D. Modin, M. Loiacono, R. Harris +16 more

    2025American Heart Journal15 citations Open access

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36. Recommended methodologies for clinical investigations of high-risk medical devices—Conclusions from the European Union CORE–MD Project

    A. Fraser, S. Buccheri, Robert A. Byrne, P. Kjaersgaard-Andersen +93 more

    2025The Lancet Regional Health - Europe15 citations Open access

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37. Facilitating participation in clinical trials during pregnancy

    N. Vousden, Richard Haynes, Sarah Findlay, P. Horby +3 more

    2023British medical journal15 citations Open access

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38. Frailty, Multimorbidity, and Polypharmacy

    Kaitlin J. Mayne, R. Sardell, N. Staplin, P. Judge +17 more

    2024American Society of Nephrology. Clinical Journal13 citations Open access

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39. Relative Effectiveness of High-Dose Versus Standard-Dose Quadrivalent Influenza Vaccine in Older Adults With Cardiovascular Disease: A Prespecified Analysis of the DANFLU-1 Randomized Clinical Trial

    Jacob Christensen, N. Johansen, D. Modin, K. H. Janstrup +15 more

    2024Circulation. Cardiovascular Quality and Outcomes12 citations

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40. Apixaban following discharge in hospitalised adults with COVID-19: Preliminary results from a multicentre, open-label, randomised controlled platform clinical trial.

    M. Toshner, C. Gamble, J. Baillie, A. Best +18 more

    2022medRxiv12 citations Open access

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41. Time of day for vaccination, outcomes, and relative effectiveness of high-dose vs. standard-dose quadrivalent influenza vaccine: a post-hoc analysis of the DANFLU-1 randomized clinical trial.

    Jacob Christensen, N. Johansen, K. Janstrup, D. Modin +16 more

    2024Journal of Infection11 citations Open access

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42. Large simple randomized controlled trials—from drugs to medical devices: lessons from recent experience

    S. Buccheri, Stefan James, Marion Mafham, M. Landray +9 more

    2025Trials10 citations Open access

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43. Effects of Empagliflozin on Urine Biomarkers in EMPA-KIDNEY.

    G. Malijan, R. Sardell, N. Staplin, O. Devuyst +22 more

    2025American Journal of Kidney Diseases10 citations Open access

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44. Effects of high‐dose versus standard‐dose quadrivalent influenza vaccine among patients with diabetes: A post‐hoc analysis of the DANFLU‐1 trial

    M. H. Højbjerg Lassen, N. Johansen, D. Modin, J. Nealon +16 more

    2024Diabetes, obesity and metabolism9 citations Open access

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45. Interference of urinary albumin-to-creatinine ratio measurement by glycosuria: clinical implications when using SGLT-2 inhibitors

    D. Chapman, P. Judge, R. Sardell, N. Staplin +10 more

    2022medRxiv9 citations Open access

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46. Effects of empagliflozin on quality of life and healthcare use and costs in chronic kidney disease: a health economic analysis of the EMPA-KIDNEY trial

    Junwen Zhou, Claire Williams, N. Staplin, P. Judge +16 more

    2025EClinicalMedicine8 citations Open access

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47. Effects of empagliflozin on conventional and exploratory acute and chronic kidney outcomes: an individual participant-level meta-analysis.

    W. Herrington, Zhao-Jing Che, R. Sardell, Alistair J. Roddick +16 more

    2025The Lancet Diabetes and Endocrinology8 citations Open access

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48. High-Dose vs Standard-Dose Influenza Vaccine in Chronic Kidney Disease: A Secondary Analysis of DANFLU-1.

    K. Bartholdy, N. Johansen, K. Janstrup, D. Modin +17 more

    2024Journal of the American College of Cardiology7 citations Open access

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49. Dimethyl fumarate in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial

    P. Horby, L. Peto, N. Staplin, M. Campbell +28 more

    2024Nature Communications7 citations Open access

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50. Reliability of major bleeding events in UK routine data versus clinical trial adjudicated follow-up data

    C. Harper, M. Mafham, W. Herrington, N. Staplin +7 more

    2023Heart7 citations Open access

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