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A. Uruno · SciRah

Researcher profile · Semantic Scholar

A. Uruno

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A. Uruno — researcher profile on SciRah

h-index: 37
Works: 113
Citations: 4,741

Most-cited papers

The Keap1-Nrf2 System Prevents Onset of Diabetes Mellitus
A. Uruno, Yuki Furusawa, Yoko Yagishita, T. Fukutomi +5 more
2013Molecular and Cellular Biology313 citations Open access
Semantic Scholar
The Keap1-Nrf2 system and diabetes mellitus.
A. Uruno, Yoko Yagishita, M. Yamamoto
2015Archives of Biochemistry and Biophysics218 citations Open access
Semantic Scholar
Accumulation of p62/SQSTM1 is associated with poor prognosis in patients with lung adenocarcinoma
D. Inoue, Takashi Suzuki, Y. Mitsuishi, Y. Miki +13 more
2012Cancer Science210 citations Open access
Semantic Scholar
Nrf2 Protects Pancreatic β-Cells From Oxidative and Nitrosative Stress in Diabetic Model Mice
Yoko Yagishita, T. Fukutomi, A. Sugawara, H. Kawamura +4 more
2014Diabetes207 citations Open access
Semantic Scholar
The Keap1-Nrf2 system as an in vivo sensor for electrophiles.
A. Uruno, H. Motohashi
2011Nitric oxide196 citations
Semantic Scholar
Immunohistochemistry of a proliferation marker Ki67/MIB1 in adrenocortical carcinomas: Ki67/MIB1 labeling index is a predictor for recurrence of adrenocortical carcinomas.
R. Morimoto, F. Satoh, O. Murakami, Takashi Suzuki +9 more
2008Endocrine journal140 citations Open access
Semantic Scholar
Nrf2 Suppresses Oxidative Stress and Inflammation in App Knock-In Alzheimer’s Disease Model Mice
A. Uruno, D. Matsumaru, R. Ryoke, Ritsumi Saito +6 more
2020Molecular and Cellular Biology132 citations Open access
Semantic Scholar
Study Profile of the Tohoku Medical Megabank Community-Based Cohort Study
A. Hozawa, K. Tanno, N. Nakaya, Tomohiro Nakamura +79 more
2020Journal of Epidemiology119 citations Open access
Semantic Scholar
Nrf2 Improves Leptin and Insulin Resistance Provoked by Hypothalamic Oxidative Stress.
Yoko Yagishita, A. Uruno, T. Fukutomi, Ritsumi Saito +6 more
2017Cell Reports114 citations Open access
Semantic Scholar
Nrf2-Mediated Regulation of Skeletal Muscle Glycogen Metabolism
A. Uruno, Yoko Yagishita, F. Katsuoka, Y. Kitajima +5 more
2016Molecular and Cellular Biology114 citations Open access
Semantic Scholar
Localization of Aldosterone-Producing Adrenocortical Adenomas: Significance of Adrenal Venous Sampling
F. Satoh, T. Abe, Masayuki Tanemoto, Masahiro Nakamura +11 more
2007Hypertension Research113 citations Open access
Semantic Scholar
All-trans retinoic acid induces in vitro angiogenesis via retinoic acid receptor: possible involvement of paracrine effects of endogenous vascular endothelial growth factor signaling.
A. Saito, A. Sugawara, A. Uruno, M. Kudo +9 more
2007Endocrinology109 citations
Semantic Scholar
The KEAP1-NRF2 System and Neurodegenerative Diseases
A. Uruno, Masayuki Yamamoto
2023Antioxidants and Redox Signaling104 citations
Semantic Scholar
Important role of heparan sulfate in postnatal islet growth and insulin secretion.
I. Takahashi, N. Noguchi, K. Nata, S. Yamada +15 more
2009Biochemical and Biophysical Research Communications - BBRC97 citations
Semantic Scholar
Nrf2 deficiency deteriorates diabetic kidney disease in Akita model mice
Ye-Xin Liu, A. Uruno, Ritsumi Saito, Naomi Matsukawa +4 more
2022Redox Biology86 citations Open access
Semantic Scholar
Transcription Factor Nrf1 Negatively Regulates the Cystine/Glutamate Transporter and Lipid-Metabolizing Enzymes
T. Tsujita, Vivian J Peirce, Liam Baird, Yuka Matsuyama +6 more
2014Molecular and Cellular Biology82 citations Open access
Semantic Scholar
Upregulation of Nitric Oxide Production in Vascular Endothelial Cells by All-trans Retinoic Acid Through the Phosphoinositide 3-Kinase/Akt Pathway
A. Uruno, A. Sugawara, H. Kanatsuka, H. Kagechika +5 more
2005Circulation78 citations Open access
Semantic Scholar
Transcription Suppression of Peroxisome Proliferator-Activated Receptor γ2 Gene Expression by Tumor Necrosis Factor α via an Inhibition of CCAAT/ Enhancer-binding Protein δ during the Early Stage of Adipocyte Differentiation
M. Kudo, A. Sugawara, A. Uruno, K. Takeuchi +1 more
200465 citations
Semantic Scholar
Effects of PPARγ on hypertension, atherosclerosis, and chronic kidney disease.
A. Sugawara, A. Uruno, M. Kudo, K. Matsuda +2 more
2010Endocrine journal63 citations Open access
Semantic Scholar
Nrf2 induces fibroblast growth factor 21 in diabetic mice
Yuki Furusawa, A. Uruno, Yoko Yagishita, Chika Higashi +1 more
2014Genes to Cells60 citations Open access
Semantic Scholar
Transcription factor NF‐E2‐related factor 1 impairs glucose metabolism in mice
Yosuke Hirotsu, Chika Higashi, T. Fukutomi, F. Katsuoka +6 more
2014Genes to Cells51 citations Open access
Semantic Scholar
Identification of Celastramycin as a Novel Therapeutic Agent for Pulmonary Arterial Hypertension-High-throughput Screening of 5,562 Compounds.
R. Kurosawa, K. Satoh, N. Kikuchi, H. Kikuchi +17 more
2019Circulation Research50 citations
Semantic Scholar
Peroxisome proliferator-activated receptor-{gamma} suppresses CYP11B2 expression and aldosterone production.
A. Uruno, K. Matsuda, N. Noguchi, T. Yoshikawa +10 more
2011Journal of Molecular Endocrinology48 citations Open access
Semantic Scholar
Expression of peroxisome proliferator-activated receptor isoform proteins in the rat kidney.
Kazunori Sato, A. Sugawara, M. Kudo, A. Uruno +2 more
2004Hypertension Research48 citations Open access
Semantic Scholar
Genetic engineering with endothelial nitric oxide synthase improves functional properties of endothelial progenitor cells from patients with coronary artery disease: an in vitro study
S. Kaur, T. R. Santhosh Kumar, A. Uruno, A. Sugawara +2 more
2009Basic Research in Cardiology44 citations
Semantic Scholar
Isocitrate dehydrogenase mutation is frequently observed in giant cell tumor of bone
Mika Kato Kaneko, Xing Liu, H. Oki, S. Ogasawara +11 more
2014Cancer Science43 citations Open access
Semantic Scholar
Upregulation of REG Iα accelerates tumor progression in pancreatic cancer with diabetes
Lin Zhou, Rui-Feng Zhang, Lishun Wang, Shaoming Shen +9 more
2010International Journal of Cancer43 citations Open access
Semantic Scholar
Nrf2 contributes to the weight gain of mice during space travel
Takafumi Suzuki, A. Uruno, Akane Yumoto, K. Taguchi +33 more
2020Communications Biology40 citations Open access
Semantic Scholar
Nrf2 represses the onset of type 1 diabetes in non-obese diabetic mice
Yoko Yagishita, A. Uruno, D. Chartoumpekis, T. Kensler +1 more
2019Journal of Endocrinology40 citations Open access
Semantic Scholar
The novel Nrf2 inducer TFM‐735 ameliorates experimental autoimmune encephalomyelitis in mice
Chika Higashi, Atsuko Kawaji, Naoto Tsuda, M. Hayashi +8 more
2017European Journal of Pharmacology37 citations
Semantic Scholar
FKBP12.6 disruption impairs glucose-induced insulin secretion.
N. Noguchi, T. Yoshikawa, T. Ikeda, I. Takahashi +7 more
2008Biochemical and Biophysical Research Communications - BBRC37 citations
Semantic Scholar
Transcription suppression of peroxisome proliferator-activated receptor gamma2 gene expression by tumor necrosis factor alpha via an inhibition of CCAAT/ enhancer-binding protein delta during the early stage of adipocyte differentiation.
M. Kudo, A. Sugawara, A. Uruno, K. Takeuchi +1 more
2004Endocrinology34 citations
Semantic Scholar
Japonica Array NEO with increased genome-wide coverage and abundant disease risk SNPs
Mika Sakurai-Yageta, Kazuki Kumada, C. Gocho, S. Makino +18 more
2020bioRxiv33 citations Open access
Semantic Scholar
Conductive Adhesive Film Expands the Utility of Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry Imaging.
D. Saigusa, Ritsumi Saito, K. Kawamoto, A. Uruno +4 more
2019Analytical Chemistry33 citations Open access
Semantic Scholar
Genome-wide Association Study of Axial Length in Population-based Cohorts in Japan
N. Fuse, Miyuki Sakurai, I. Motoike, Kaname Kojima +29 more
2022Ophthalmology Science28 citations Open access
Semantic Scholar
Multiple measurements of the urinary sodium-to-potassium ratio strongly related home hypertension: TMM Cohort Study
M. Kogure, Takumi Hirata, N. Nakaya, N. Tsuchiya +13 more
2019Hypertension Research28 citations Open access
Semantic Scholar
All‐trans retinoic acid and a novel synthetic retinoid tamibarotene (Am80) differentially regulate CD38 expression in human leukemia HL‐60 cells: possible involvement of protein kinase C‐δ
A. Uruno, N. Noguchi, K. Matsuda, K. Nata +7 more
2011Journal of Leukocyte Biology28 citations
Semantic Scholar
Genetic loci for lung function in Japanese adults with adjustment for exhaled nitric oxide levels as airway inflammation indicator
M. Yamada, I. Motoike, Kaname Kojima, N. Fuse +22 more
2021Communications Biology27 citations Open access
Semantic Scholar
Metabolic basis of neuronal vulnerability to ischemia; an in vivo untargeted metabolomics approach
Sherif Rashad, D. Saigusa, Takahiro Yamazaki, Yotaro Matsumoto +6 more
2020Scientific Reports26 citations Open access
Semantic Scholar
Halofuginone micelle nanoparticles eradicate Nrf2-activated lung adenocarcinoma without systemic toxicity.
Harit Panda, Mikiko Suzuki, Mitsuru Naito, Ritsumi Saito +5 more
2022Free Radical Biology & Medicine25 citations Open access
Semantic Scholar
Nrf2 plays a critical role in the metabolic response during and after spaceflight
A. Uruno, D. Saigusa, Takafumi Suzuki, Akane Yumoto +18 more
2021Communications Biology24 citations Open access
Semantic Scholar
Maternal Baseline Characteristics and Perinatal Outcomes: The Tohoku Medical Megabank Project Birth and Three-Generation Cohort Study
J. Sugawara, M. Ishikuro, T. Obara, T. Onuma +28 more
2020Journal of Epidemiology24 citations Open access
Semantic Scholar
Gene expression changes related to bone mineralization, blood pressure and lipid metabolism in mouse kidneys after space travel.
N. Suzuki, Yuma Iwamura, T. Nakai, Koichiro Kato +13 more
2021Kidney International23 citations
Semantic Scholar
Nrf2 activation in myeloid cells and endothelial cells differentially mitigates sickle cell disease pathology in mice.
Nadine Keleku-Lukwete, Mikiko Suzuki, Harit Panda, Akihito Otsuki +5 more
2019Blood Advances23 citations Open access
Semantic Scholar
Alteration of the lysophosphatidic acid and its precursor lysophosphatidylcholine levels in spinal cord stenosis: A study using a rat cauda equina compression model
B. Uranbileg, N. Ito, M. Kurano, D. Saigusa +9 more
2019Scientific Reports23 citations Open access
Semantic Scholar
Effects of RXR Agonists on Cell Proliferation/Apoptosis and ACTH Secretion/Pomc Expression
Akiko Saito-hakoda, A. Uruno, Atsushi Yokoyama, K. Shimizu +14 more
2015PLoS ONE23 citations Open access
Semantic Scholar
PPARγ Agonist Beyond Glucose Lowering Effect
A. Sugawara, A. Uruno, M. Kudo, K. Matsuda +2 more
2011The Korean Journal of Internal Medicine22 citations Open access
Semantic Scholar
Thiazolidinediones inhibit REG Ialpha gene transcription in gastrointestinal cancer cells.
A. Yamauchi, I. Takahashi, S. Takasawa, K. Nata +9 more
2009Biochemical and Biophysical Research Communications - BBRC22 citations
Semantic Scholar
Carotid Intima Media Thickness and Risk Factor for Atherosclerosis: Tohoku Medical Megabank Community-Based Cohort Study
Masato Takase, N. Nakaya, Tomohiro Nakamura, M. Kogure +16 more
2023Journal of atherosclerosis and thrombosis21 citations Open access
Semantic Scholar
Association between the combined fat mass and fat-free mass index and hypertension: The Tohoku Medical Megabank Community-based Cohort Study
Masato Takase, Tomohiro Nakamura, N. Tsuchiya, M. Kogure +14 more
2021Clinical and experimental hypertension21 citations Open access
Semantic Scholar

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A. Sugawara×17
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M. Yamamoto×16
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S. Ito×12
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D. Saigusa×11
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Yoko Yagishita — researcher profile on SciRah

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M. Kudo — researcher profile on SciRah

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A. Hozawa — researcher profile on SciRah

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J. Sugawara — researcher profile on SciRah

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N. Fuse — researcher profile on SciRah