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C. Ashendel · SciRah

Researcher profile · Semantic Scholar

C. Ashendel

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C. Ashendel — researcher profile on SciRah

h-index: 27
Works: 64
Citations: 3,574

Most-cited papers

Wortmannin, a potent and selective inhibitor of phosphatidylinositol-3-kinase.
G. Powis, R. Bonjouklian, M. Berggren, A. Gallegos +6 more
1994Cancer Research745 citations
Semantic Scholar
The phorbol ester receptor: a phospholipid-regulated protein kinase.
C. Ashendel
1985Biochimica et Biophysica Acta463 citations
Semantic Scholar
Inhibition by prostaglandin synthesis inhibitors of the induction of epidermal ornithine decarboxylase activity, the accumulation of prostaglandins, and tumor promotion caused by 12-O-tetradecanoylphorbol-13-acetate.
A. K. Verma, C. Ashendel, R. Boutwell
1980Cancer Research301 citations
Semantic Scholar
Kinase inhibitors from Polygonum cuspidatum.
G. S. Jayatilake, H. Jayasuriya, Eung-Seok Lee, N. M. Koonchanok +4 more
1993Journal of Natural Products217 citations Open access
Semantic Scholar
Protein kinase activity associated with a phorbol ester receptor purified from mouse brain.
C. Ashendel, J. Staller, R. Boutwell
1983Cancer Research151 citations
Semantic Scholar
Identification of a calcium- and phospholipid- dependent phorbol ester binding activity in the soluble fraction of mouse tissues.
C. Ashendel, J. Staller, R. Boutwell
1983Biochemical and Biophysical Research Communications - BBRC147 citations
Semantic Scholar
Hepatitis B Virus X Protein Differentially Activates RAS-RAF-MAPK and JNK Pathways in X-transforming Versus Non-transforming AML12 Hepatocytes*
C. Tarn, Sook Lee, Yong Hu, C. Ashendel +1 more
2001Journal of Biological Chemistry97 citations Open access
Semantic Scholar
Direct measurement of specific binding of highly lipophilic phorbol diester to mouse epidermal membranes using cold acetone.
C. Ashendel, R. Boutwell
1981Biochemical and Biophysical Research Communications - BBRC88 citations
Semantic Scholar
Signaling through mitogen-activated protein kinase and Rac/Rho does not duplicate the effects of activated Ras on skeletal myogenesis
M. Ramocki, S. Johnson, Michael A. White, C. Ashendel +2 more
1997Molecular and Cellular Biology85 citations Open access
Semantic Scholar
Prostaglandin E and F levels in mouse epidermis are increased by tumor-promoting phorbol esters.
C. Ashendel, R. Boutwell
1979Biochemical and Biophysical Research Communications - BBRC83 citations
Semantic Scholar
Isolation and characterization of the principal ATPase associated with transitional endoplasmic reticulum of rat liver
L. Zhang, C. Ashendel, G. Becker, D. Morré
1994Journal of Cell Biology82 citations Open access
Semantic Scholar
Differing modulation of protein kinase C by bryostatin 1 and phorbol esters in JB6 mouse epidermal cells.
Andrew S. Kraft, J. Reeves, C. Ashendel
1988Journal of Biological Chemistry64 citations Open access
Semantic Scholar
Mouse skin: a useful model system for studying the mechanism of chemical carcinogenesis.
R. Boutwell, A. K. Verma, C. Ashendel, E. G. Astrup
1982Carcinogenesis; a comprehensive survey64 citations
Semantic Scholar
Partial down-regulation of protein kinase C in C3H 10T 1/2 mouse fibroblasts transfected with the human Ha-ras oncogene.
C. M. Weyman, Elizabeth J. Taparowsky, M. Wolfson, C. Ashendel
1988Cancer Research61 citations
Semantic Scholar
Automated simultaneous qualitative and quantitative analysis of complex organic mixtures with a gas chromatography-mass spectrometry-computer system
S. C. Gates, M. J. Smisko, C. Ashendel, N. D. Young +2 more
197859 citations
Semantic Scholar
D-501036, a novel selenophene-based triheterocycle derivative, exhibits potent in vitro and in vivo antitumoral activity which involves DNA damage and ataxia telangiectasia–mutated nuclear protein kinase activation
S. Juang, C. Lung, P. Hsu, K. Hsu +17 more
2007Molecular Cancer Therapeutics58 citations
Semantic Scholar
Workgroup 3: Transgenic and reconstitution models of prostate cancer
Jeffrey E. Green, Norman M. Greenberg, C. Ashendel, J. Barrett +6 more
1998The Prostate57 citations
Semantic Scholar
Solubilization, purification, and reconstitution of a phorbol ester receptor from the particulate protein fraction of mouse brain.
C. Ashendel, J. Staller, R. Boutwell
1983Cancer Research49 citations
Semantic Scholar
Inhibition of myogenesis by the H-ras oncogene: implication of a role for protein kinase C
T. B. Vaidya, C. M. Weyman, Dorothy Teegarden, C. Ashendel +1 more
1991Journal of Cell Biology48 citations Open access
Semantic Scholar
Treatment of T cells with 2-hydroxymyristic acid inhibits the myristoylation and alters the stability of p56lck.
Monica J. S. Nadler, M. Harrison, C. Ashendel, J. Cassady +1 more
1993Biochemistry47 citations
Semantic Scholar
Oncogene signal transduction inhibitors from medicinal plants.
C. J. Chang, C. Ashendel, R. Geahlen, J. Mclaughlin +1 more
1996In Vivo43 citations
Semantic Scholar
Inhibition of 7-bromomethylbenz[a]anthracene-promoted mouse skin tumor formation by retinoic acid and dexamethasone.
A. K. Verma, C. Garcia, C. Ashendel, R. Boutwell
1983Cancer Research43 citations
Semantic Scholar
Novel protein kinase C inhibitors: α-terthiophene derivatives
Darrick S. H. L. Kim, C. Ashendel, Qin Zhou, Ching-Te Chang +2 more
199837 citations
Semantic Scholar
Specific high-affinity binding of the phorbol ester tumor promoter 12-O-tetradecanoylphorbol-13-acetate to isolated nuclei and nuclear macromolecules in mouse epidermis.
Frank W. Perrella, C. Ashendel, R. Boutwell
1982Cancer Research32 citations
Semantic Scholar
Synthesis and MEK1 inhibitory activities of imido-substituted 2-chloro-1,4-naphthoquinones.
O. Bakare, C. Ashendel, Hai-Ruo Peng, L. Zalkow +1 more
2003Bioorganic & Medicinal Chemistry31 citations
Semantic Scholar
Aluminum negatively impacts calcium utilization and bone in calcium-deficient rats
Tasleem A. Zafar, D. Teegarden, C. Ashendel, M. Dunn +1 more
200430 citations
Semantic Scholar
Activation of T Cell Raf-1 at Mitosis Requires the Protein-tyrosine Kinase Lck*
N. Pathan, C. Ashendel, R. Geahlen, M. Harrison
1996Journal of Biological Chemistry28 citations Open access
Semantic Scholar
A multiwell assay for inhibitors of phosphatidylinositol-3-kinase and the identification of natural product inhibitors.
T. Frew, G. Powis, M. Berggren, R. Abraham +6 more
1994Anticancer Research25 citations
Semantic Scholar
Partial characterization of epidermal protein kinase C in mice sensitive or resistant to phorbol ester
Naoki Hirabayashi, Barbour S. Warren, Xiao-Jing Wang, Svend Petersen‐Marht +4 more
1990Molecular Carcinogenesis24 citations
Semantic Scholar
Characterization of the in Vivo Sites of Serine Phosphorylation on Lck Identifying Serine 59 as a Site of Mitotic Phosphorylation*
K. Kesavan, C. Isaacson, C. Ashendel, R. Geahlen +1 more
2002Journal of Biological Chemistry23 citations Open access
Semantic Scholar
The induction of ornithine decarboxylase activity and its control in mouse skin epidermis.
R. Boutwell, T. O'Brien, Ajit K. Verma, R. Weekes +3 more
1978Advances in Enzyme Regulation23 citations
Semantic Scholar
Novel protein kinase C inhibitors: synthesis and PKC inhibition of beta-substituted polythiophene derivatives.
Wei-Chu Xu, Qin Zhou, C. Ashendel, Ching-Te Chang +1 more
1999Bioorganic & Medicinal Chemistry Letters21 citations Open access
Semantic Scholar
Advances with phospholipid signalling as a target for anticancer drug development.
G. Powis, M. Berggren, A. Gallegos, T. Frew +6 more
1995Acta Biochimica Polonica21 citations Open access
Semantic Scholar
Differential responsiveness to phorbol esters correlates with differential expression of protein kinase C in KG-1 and KG-1a human myeloid leukemia cells.
W. Hooper, Robert T. Abraham, C. Ashendel, G. Woloschak
1989Biochimica et Biophysica Acta21 citations
Semantic Scholar
A multisample assay for inhibitors of phosphatidylinositol phospholipase C: identification of naturally occurring peptide inhibitors with antiproliferative activity.
S. Hill, R. Bonjouklian, G. Powis, R. Abraham +2 more
1994Anti-Cancer Drug Design18 citations
Semantic Scholar
Tumor promoter 12-O-tetradecanoylphorbol-13-acetate and sn-1,2-dioctanoylglycerol increase the phosphorylation of protein kinase C in cells.
Carlos A. Molina, C. Ashendel
1991Cancer Research18 citations
Semantic Scholar
Oncogene signal transduction inhibitors from Chinese medicinal plants
Ching-jer Chang, C. Ashendel, T. Chan, R. Geahlen +2 more
199915 citations
Semantic Scholar
Prenylated Flavanones from Derris laxiflora
Young Ho Kim, Eung-Seok Lee, N. M. Koonchanok, R. Geahlen +2 more
199515 citations
Semantic Scholar
Novel quinone antiproliferative inhibitors of phosphatidylinositol-3-kinase.
T. Frew, G. Powis, M. Berggren, A. Gallegos +6 more
1995Anti-Cancer Drug Design14 citations
Semantic Scholar
Increased intracellular Ca2+ signaling caused by the antitumor agent helenalin and its analogues
G. Powis, A. Gallegos, R. Abraham, C. Ashendel +3 more
1994Cancer Chemotherapy and Pharmacology14 citations
Semantic Scholar
Isolation of cloned mouse protein kinase C beta-II cDNA and its sequence.
Yong-Ming Tang, C. Ashendel
1990Nucleic Acids Research14 citations Open access
Semantic Scholar
Diet, signal transduction and carcinogenesis.
C. Ashendel
1995Journal of NutriLife10 citations
Semantic Scholar
Hemicholinium and related lipids: inhibitors of protein kinase C.
G. Kumaravel, C. Ashendel, Richard D. Gandour
1993Journal of Medicinal Chemistry9 citations Open access
Semantic Scholar
Inhibition of intracellular Ca2+ signalling, cytotoxicity and antitumor activity of the herbicide oryzalin and its analogues
G. Powis, A. Gallegos, R. Abraham, C. Ashendel +6 more
1997Cancer Chemotherapy and Pharmacology8 citations
Semantic Scholar
Structure Activity Relationship Study of Emodin Derivatives Based on the Protein-Tyrosine Kinase and Protein Kinase C Inhibitory Activities and Cytotoxicity
Darrick S. H. L. Kim, N. M. Koonchanok, R. Geahlen, C. Ashendel +1 more
19978 citations
Semantic Scholar
Partial suppression of tumorigenicity in a human lung cancer cell line transfected with Krev‐1
J. Caamano, M. DiRado, T. Lizasa, S. Momiki +4 more
1992Molecular Carcinogenesis8 citations
Semantic Scholar
Determination of enzyme kinetic parameters by continuous addition of substrate to a single reaction mixture and analysis by a tangent-slope procedure. II. Application of the method to soluble and immobilized enzymes.
David J. Leblond, C. Ashendel, W. A. Wood
1980Analytical Biochemistry8 citations
Semantic Scholar
Synthesis of Optically Pure Cyclic Lipoidal Ammonium Salts and Evaluation of Inhibition of Protein Kinase C
M. Hubieki, R. Gandour, C. Ashendel
19967 citations
Semantic Scholar
Determination of enzyme kinetic parameters by continuous addition of substrate to a single reaction mixture and analysis by a tangent-slope procedure. I. Analysis of the method using computed progress curves.
David J. Leblond, C. Ashendel, W. A. Wood
1980Analytical Biochemistry7 citations
Semantic Scholar
Bioactive compounds from Psorothamnus junceus.
Hong-Bing Zhang, Xiao-Hua Li, C. Ashendel, Ching-jer Chang
2000Journal of Natural Products6 citations
Semantic Scholar

Frequent co-authors

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R. Boutwell×10
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R. Boutwell — researcher profile on SciRah
R. Geahlen×8
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R. Geahlen — researcher profile on SciRah
Ching-jer Chang×8
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Ching-jer Chang — researcher profile on SciRah
G. Powis×7
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G. Powis — researcher profile on SciRah

×7

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R. Abraham — researcher profile on SciRah

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L. Zalkow — researcher profile on SciRah

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A. Gallegos — researcher profile on SciRah

R. Bonjouklian×4

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R. Bonjouklian — researcher profile on SciRah

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M. Berggren — researcher profile on SciRah

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A. K. Verma — researcher profile on SciRah

N. M. Koonchanok×3

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N. M. Koonchanok — researcher profile on SciRah

J. Mclaughlin×3

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J. Mclaughlin — researcher profile on SciRah