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J. Gauldie · SciRah

Researcher profile · Semantic Scholar

J. Gauldie

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J. Gauldie — researcher profile on SciRah

h-index: 93
Works: 413
Citations: 31K

Most-cited papers

Ly6Chi monocytes direct alternatively activated profibrotic macrophage regulation of lung fibrosis.
M. Gibbons, A. Mackinnon, P. Ramachandran, K. Dhaliwal +11 more
2011American Journal of Respiratory and Critical Care Medicine466 citations Open access
Semantic Scholar
Metastatic Growth from Dormant Cells Induced by a Col-I Enriched Fibrotic Environment
D. Barkan, Lara H. el Touny, A. Michalowski, Jane Ann Smith +7 more
2010Cancer Research366 citations Open access
Semantic Scholar
Pulmonary hypertension and idiopathic pulmonary fibrosis: a tale of angiogenesis, apoptosis, and growth factors.
L. Farkas, J. Gauldie, N. Voelkel, M. Kolb
2011American Journal of Respiratory Cell and Molecular Biology210 citations
Semantic Scholar
Dissecting fibrosis: therapeutic insights from the small-molecule toolbox
C. Nanthakumar, R. Hatley, Seble Lemma, J. Gauldie +2 more
2015Nature reviews. Drug discovery208 citations
Semantic Scholar
The importance of interventional timing in the bleomycin model of pulmonary fibrosis
P. Kolb, C. Upagupta, M. Vierhout, Ehab A. Ayaub +6 more
2020European Respiratory Journal201 citations Open access
Semantic Scholar
A Human Type 5 Adenovirus–Based Tuberculosis Vaccine Induces Robust T Cell Responses in Humans Despite Preexisting Anti-Adenovirus Immunity
F. Smaill, M. Jeyanathan, M. Smieja, M. F. Medina +12 more
2013Science Translational Medicine201 citations
Semantic Scholar
Mouse and human lung fibroblasts regulate dendritic cell trafficking, airway inflammation, and fibrosis through integrin αvβ8-mediated activation of TGF-β.
H. Kitamura, S. Cambier, Sangeeta Somanath, T. Barker +14 more
2011Journal of Clinical Investigation179 citations Open access
Semantic Scholar
Stretch-induced Activation of Transforming Growth Factor-β1 in Pulmonary Fibrosis.
Aaron Froese, C. Shimbori, P. Bellaye, M. Inman +6 more
2016American Journal of Respiratory and Critical Care Medicine172 citations
Semantic Scholar
Transforming Growth Factor-β: Activation by Neuraminidase and Role in Highly Pathogenic H5N1 Influenza Pathogenesis
C. Carlson, Elizabeth A. Turpin, L. Moser, Kevin B. O'Brien +7 more
2010PLoS Pathogens150 citations Open access
Semantic Scholar
Nanoscale dysregulation of collagen structure-function disrupts mechano-homeostasis and mediates pulmonary fibrosis
Mark G. Jones, O. Andriotis, J. Roberts, Kerry Lunn +30 more
2018eLife136 citations Open access
Semantic Scholar
Cardiovascular , Pulmonary , and Renal Pathology Matrix Metalloproteinase 3 Is a Mediator of Pulmonary Fibrosis
C. Yamashita, L. Dolgonos, R. Zemans, S. Young +11 more
2011134 citations
Semantic Scholar
Effects of budesonide and formoterol on allergen-induced airway responses, inflammation, and airway remodeling in asthma.
M. Kelly, T. M. O'Connor, R. Leigh, J. Otis +4 more
2010Journal of Allergy and Clinical Immunology117 citations
Semantic Scholar
Negative regulation of lung inflammation and immunopathology by TNF-α during acute influenza infection.
D. Damjanovic, M. Divangahi, Kapilan Kugathasan, C. Small +5 more
2011American Journal of Pathology112 citations Open access
Semantic Scholar
Inhibition of HSP27 blocks fibrosis development and EMT features by promoting Snail degradation
G. Wettstein, P. Bellaye, M. Kolb, A. Hammann +11 more
2013The FASEB Journal107 citations Open access
Semantic Scholar
Streptococcus pneumoniae triggers progression of pulmonary fibrosis through pneumolysin
S. Knippenberg, B. Ueberberg, R. Maus, Jennifer Bohling +16 more
2015Thorax98 citations Open access
Semantic Scholar
FPR-1 is an important regulator of neutrophil recruitment and a tissue-specific driver of pulmonary fibrosis
J. Leslie, B. Millar, A. M. Del Carpio Pons, Rachel A. Burgoyne +18 more
2020JCI Insight97 citations Open access
Semantic Scholar
Inflammation Induced by MMP-9 Enhances Tumor Regression of Experimental Breast Cancer
K. S. Leifler, S. Svensson, Annelie Abrahamsson, Christina Bendrik +4 more
2013Journal of Immunology97 citations Open access
Semantic Scholar
Fibroblast growth factor‐1 attenuates TGF‐β1‐induced lung fibrosis
C. Shimbori, P. Bellaye, J-X Xia, J. Gauldie +6 more
2016Journal of Pathology93 citations Open access
Semantic Scholar
Oxidative stress contributes to the induction and persistence of TGF-β1 induced pulmonary fibrosis.
Ye Cui, J. Robertson, Shyam S. Maharaj, L. Waldhauser +5 more
2011International Journal of Biochemistry and Cell Biology90 citations
Semantic Scholar
Role of matrix metalloprotease-2 and MMP-9 in experimental lung fibrosis in mice
Tina Bormann, R. Maus, J. Stolper, Meritxell Tort Tarrés +7 more
2022Respiratory Research86 citations Open access
Semantic Scholar
Local delivery of Granulocyte/Macrophage Colony Stimulating Factor protects mice from lethal pneumococcal pneumonia
K. Steinwede, Ole Tempelhof, Kristine Bolte, R. Maus +11 more
2011Journal of Immunology82 citations Open access
Semantic Scholar
Mechanical stress-induced mast cell degranulation activates TGF-β1 signalling pathway in pulmonary fibrosis
C. Shimbori, C. Upagupta, P. Bellaye, Ehab A. Ayaub +8 more
2019Thorax81 citations Open access
Semantic Scholar
Ocular gene transfer of active TGF-beta induces changes in anterior segment morphology and elevated IOP in rats.
J. Robertson, E. Golesic, J. Gauldie, J. West-Mays
2010Investigative Ophthalmology and Visual Science71 citations
Semantic Scholar
Transient overexpression of Gremlin results in epithelial activation and reversible fibrosis in rat lungs.
L. Farkas, D. Farkas, J. Gauldie, D. Warburton +2 more
2011American Journal of Respiratory Cell and Molecular Biology66 citations Open access
Semantic Scholar
The small heat‐shock protein αB‐crystallin is essential for the nuclear localization of Smad4: impact on pulmonary fibrosis
P. Bellaye, G. Wettstein, O. Burgy, V. Besnard +11 more
2014Journal of Pathology63 citations
Semantic Scholar
A novel profibrotic mechanism mediated by TGF-β-stimulated collagen prolyl hydroxylase expression in fibrotic lung mesenchymal cells
Yongfeng Luo, Wei Xu, Hui Chen, D. Warburton +6 more
2015Journal of Pathology62 citations Open access
Semantic Scholar
Macitentan reduces progression of TGF-β1-induced pulmonary fibrosis and pulmonary hypertension
P. Bellaye, Toyoshi Yanagihara, E. Granton, Seidai Sato +8 more
2018European Respiratory Journal58 citations Open access
Semantic Scholar
Lysyl Oxidase‐Like 1 Protein Deficiency Protects Mice from Adenoviral Transforming Growth Factor‐&bgr;1‐induced Pulmonary Fibrosis
P. Bellaye, C. Shimbori, C. Upagupta, Seidai Sato +4 more
2017American Journal of Respiratory Cell and Molecular Biology58 citations
Semantic Scholar
Matrix metalloproteinase-19 promotes metastatic behavior in vitro and is associated with increased mortality in non-small cell lung cancer.
Guo-Ying Yu, J. Herazo-Maya, T. Nukui, M. Romkes +7 more
2014American Journal of Respiratory and Critical Care Medicine57 citations Open access
Semantic Scholar
Extracellular matrix microenvironment contributes actively to pulmonary fibrosis
C. Shimbori, J. Gauldie, M. Kolb
2013Current opinion in pulmonary medicine54 citations
Semantic Scholar
Fibrocytes and Fibroblasts - where are we now.
S. Chong, Seidai Sato, M. Kolb, J. Gauldie
2019International Journal of Biochemistry and Cell Biology52 citations
Semantic Scholar
Amplification of TGFβ Induced ITGB6 Gene Transcription May Promote Pulmonary Fibrosis
Amanda L. Tatler, Amanda T. Goodwin, O. Gbolahan, Gauri Saini +10 more
2016PLoS ONE47 citations Open access
Semantic Scholar
Surfactant dysfunction and alveolar collapse are linked with fibrotic septal wall remodeling in the TGF-β1-induced mouse model of pulmonary fibrosis
Lukas Beike, C. Wrede, J. Hegermann, E. Lopez-Rodriguez +6 more
2019Laboratory Investigation44 citations Open access
Semantic Scholar
Modulation of pulmonary fibrosis by IL-13Rα2.
R. V. Lumsden, Julie C. Worrell, D. Boylan, Sinead M. Walsh +9 more
2015American Journal of Physiology - Lung cellular and Molecular Physiology42 citations
Semantic Scholar
Molecular mechanisms of MMP9 overexpression and its role in emphysema pathogenesis of Smad3-deficient mice.
Bing Xu, Hui Chen, Wei Xu, Wen-Ming Zhang +6 more
2012American Journal of Physiology - Lung cellular and Molecular Physiology40 citations Open access
Semantic Scholar
The FMS-like tyrosine kinase-3 ligand/lung dendritic cell axis contributes to regulation of pulmonary fibrosis
Meritxell Tort Tarrés, F. Aschenbrenner, R. Maus, J. Stolper +11 more
2019Thorax36 citations Open access
Semantic Scholar
CALL Translational Research in Acute Lung Injury and Pulmonary Fibrosis Surfactant dysfunction during overexpression of TGF- (cid:2) 1 precedes proﬁbrotic lung remodeling in vivo
E. Lopez-Rodriguez, C. Boden, M. Echaide, J. Pérez-Gil +5 more
201636 citations
Semantic Scholar
Cigarette smoke exposure aggravates air space enlargement and alveolar cell apoptosis in Smad3 knockout mice.
L. Farkas, D. Farkas, D. Warburton, J. Gauldie +4 more
2011American Journal of Physiology - Lung cellular and Molecular Physiology33 citations
Semantic Scholar
Let It Be: microRNAs impact interstitial lung disease.
W. Lawson, T. Blackwell, J. Gauldie
2011American Journal of Respiratory and Critical Care Medicine32 citations
Semantic Scholar
Regulatory T Cells Limit Pneumococcus-Induced Exacerbation of Lung Fibrosis in Mice
Steffi Moyé, Tina Bormann, R. Maus, T. Sparwasser +7 more
2020Journal of Immunology21 citations Open access
Semantic Scholar
Fibrocytes in chronic lung disease--facts and controversies.
Shyam S. Maharaj, E. Baroke, J. Gauldie, M. Kolb
2012Pulmonary Pharmacology & Therapeutics20 citations
Semantic Scholar
Role of the COX2-PGE2 axis in S. pneumoniae induced exacerbation of experimental fibrosis.
Tina Bormann, R. Maus, J. Stolper, D. Jonigk +4 more
2020American Journal of Physiology - Lung cellular and Molecular Physiology16 citations
Semantic Scholar
New treatment and markers of prognosis for idiopathic pulmonary fibrosis: lessons learned from translational research
E. Baroke, J. Gauldie, M. Kolb
2013Expert Review of Respiratory Medicine14 citations
Semantic Scholar
B Cells Are Not Involved in the Regulation of Adenoviral TGF-β1– or Bleomycin-Induced Lung Fibrosis in Mice
M. Moog, C. Hinze, Tina Bormann, F. Aschenbrenner +8 more
2022Journal of Immunology13 citations Open access
Semantic Scholar
Treatment combining RU486 and Ad5IL-12 vector attenuates the growth of experimentally formed prostate tumors and induces changes in the sentinel lymph nodes of mice
C. Gabaglia, Alexandra A DeLaney, J. Gee, R. Halder +4 more
2010Journal of Translational Medicine13 citations Open access
Semantic Scholar
Idiopathic pulmonary fibrosis: the matrix is the message.
M. Kolb, J. Gauldie
2011American Journal of Respiratory and Critical Care Medicine12 citations
Semantic Scholar
Mechanical stress-induced mast cell degranulation activates TGFβ-1 signalling pathway in pulmonary fibrosis
C. Shimbori, P. Bellaye, C. Upagupta, J. Gauldie +1 more
20168 citations
Semantic Scholar
Inhibition of intimal hyperplasia after stenting by over-expression of p15: a member of the INK4 family of cyclin-dependent kinase inhibitors.
A. Segev, N. Nili, B. Qiang, Azriel Osherov +8 more
2011Journal of Molecular and Cellular Cardiology7 citations
Semantic Scholar
Have advanced research technologies made real impact on respiratory medicine?
K. Ask, O. Eickelberg, J. Gauldie, N. Kaminski +1 more
2010Respirology (Carlton South. Print)7 citations Open access
Semantic Scholar
Role of dendritic cells in pulmonary fibrosis in mice
M. T. Tarrés, R. Maus, J. Stolper, F. Aschenbrenner +4 more
20166 citations
Semantic Scholar

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