Researcher profile · Semantic Scholar

U. Fruth

h-index: 19
Works: 38
Citations: 1,520

Most-cited papers

Mice from a genetically resistant background lacking the interferon gamma receptor are susceptible to infection with Leishmania major but mount a polarized T helper cell 1-type CD4+ T cell response
K. Swihart, U. Fruth, N. Messmer, K. Hug +5 more
1995Journal of Experimental Medicine286 citations Open access
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Leishmania major interferes with antigen presentation by infected macrophages.
U. Fruth, N. Solioz, J. Louis
1993Journal of Immunology133 citations
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New live mycobacterial vaccines: the Geneva consensus on essential steps towards clinical development.
A. Kamath, U. Fruth, Michael J. Brennan, R. Dobbelaer +7 more
2005Vaccine124 citations Open access
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The second Geneva Consensus: Recommendations for novel live TB vaccines.
K. B. Walker, Michael J. Brennan, M. Ho, J. Eskola +7 more
2010Vaccine116 citations
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Immunological Outcomes of New Tuberculosis Vaccine Trials: WHO Panel Recommendations
W. Hanekom, Hazel M. Dockrell, T. Ottenhoff, T. M. Doherty +6 more
2008PLoS Medicine101 citations Open access
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Inhibition of Mycobacterial Growth In Vitro following Primary but Not Secondary Vaccination with Mycobacterium bovis BCG
H. Fletcher, R. Tanner, R. Wallis, J. Meyer +12 more
2013Clinical and Vaccine Immunology84 citations Open access
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Planning to improve global health: the next decade of tuberculosis control.
D. Maher, C. Dye, K. Floyd, A. Pantoja +10 more
2007Bulletin of the World Health Organization70 citations Open access
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Report on a WHO consultation on the characterisation of BCG strains, Imperial College, London 15-16 December 2003.
M. Corbel, U. Fruth, Elwyn Griffiths, I. Knezevic
2004Vaccine58 citations
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Development of New Tuberculosis Vaccines: A Global Perspective on Regulatory Issues
M. Brennan, U. Fruth, J. Milstien, R. Tiernan +2 more
2007PLoS Medicine56 citations Open access
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A Postgenomic Approach to Identification ofMycobacterium leprae-Specific Peptides as T-Cell Reagents
H. Dockrell, S. Brahmbhatt, B. Robertson, S. Britton +13 more
2000Infection and Immunity51 citations Open access
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A novel serine proteinase (HuTSP) isolated from a cloned human CD8+ cytolytic T cell line is expressed and secreted by activated CD4+ and CD8+ lymphocytes
U. Fruth, F. Sinigaglia, M. Schlesier, Jochen Kilgus +2 more
1987European Journal of Immunology50 citations
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A review of vaccine research and development: tuberculosis.
M. Girard, U. Fruth, M. Kieny
2005Vaccine45 citations
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HIV Vaccine-Induced Sero-Reactivity: A Challenge for Trial Participants, Researchers, and Physicians
Yegor Voronin, H. Zinszner, Carissa Karg, Katie Brooks +21 more
2015Vaccine44 citations Open access
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Expression of cytoplasmic granules with T cell‐associated serine proteinase‐1 activity in Ly‐2(CD8) T lymphocytes responding to lymphocytic choriomeningitis virus in vivo
Michael D. Kramer, U. Fruth, H. Simon, M. M. Simon
1989European Journal of Immunology42 citations
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Vaccines against sexually transmitted infections: the way forward.
N. Broutet, U. Fruth, C. Deal, Sami L. Gottlieb +1 more
2014Vaccine41 citations
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Release of biologically active fragments from human plasma-fibronectin by murine T cell-specific proteinase 1 (TSP-1).
M. Simon, M. Prester, G. Nerz, M. Kramer +1 more
1988Biological Chemistry Hoppe-Seyler33 citations
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Prospects for new TB vaccines: Stop TB Working Group on TB Vaccine Development.
U. Fruth, D. Young
2004The International Journal of Tuberculosis and Lung Disease30 citations
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Mice from a Genetically Resistant Background Lacking the Interferon Y Receptor are Susceptible to Infection with Ieishmania major but Mount a Polarized T Helper Cell 1-type CD 4 + T Cell Response
K. Swihart, U. Fruth, N. Messmer, K. Hug +5 more
199523 citations
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An inhibitor specific for the mouse T‐cell associated serine proteinase 1 (TSP‐1) inhibits the cytolytic potential of cytoplasmic granules but not of intact cytolytic T cells
M. M. Simon, M. Prester, Michael D. Kramer, U. Fruth
1989Journal of Cellular Biochemistry21 citations
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Global Forum on TB Vaccine Research and Development. World Health Organization, June 7-8 2001, Geneva.
M. Brennan, U. Fruth
2001Tuberculosis16 citations
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Induction of T cell serine proteinase 1 (TSP‐1)‐specific mRNA in mouse T lymphocytes
H. Simon, U. Fruth, C. Eckerskorn, F. Lottspeich +3 more
1988European Journal of Immunology15 citations
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Diagnostic assays for leprosy based on T-cell epitopes.
Hazel M. Dockrell, S. Brahmbhatt, B. Robertson, S. Britton +13 more
2000Leprosy Review12 citations Open access
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Immunobiology of experimental leishmaniasis
I. Müller, U. Fruth, J. Louis
2004Medical Microbiology and Immmunology11 citations
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Determination of frequency of T cells expressing the T cell‐specific serine proteinase 1 (TSP‐1) reveals two types of L3T4+ T lymphocytes
U. Fruth, G. Nerz, M. Prester, H. Simon +2 more
1988European Journal of Immunology11 citations
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The blueprint for vaccine research & development: walking the path for better TB vaccines.
C. Lienhardt, U. Fruth, Michel Gréco
2012Tuberculosis10 citations
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Regulation of mouse T cell associated serine proteinase-1 (MTSP-1) by proteinase inhibitors and sulfated polysaccharides.
M. Simon, T. Tran, U. Fruth, D. Gurwitz +1 more
1990Biological Chemistry Hoppe-Seyler8 citations
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Human T cell specific proteinase (HuTSP) is encoded by the T cell and natural killer cell specific human Hanukah factor (HuHF) gene
U. Fruth, C. Eckerskorn, F. Lottspeich, Michael D. Kramer +2 more
1988FEBS Letters6 citations
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Evidence for multiple functions of T-lymphocytes associated serine proteinases.
M. M. Simon, U. Fruth, H. Simon, Steffen Gay +1 more
1989Advances in Experimental Medicine and Biology4 citations
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Considerations regarding efficacy endpoints in HIV vaccine trials: executive summary and recommendations of an expert consultation jointly organized by WHO, UNAIDS and ANRS in support of the Global HIV Vaccine Enterprise.
U. Fruth
2009Vaccine3 citations
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New Generation Tuberculosis Vaccines for Targeted Populations
U. Fruth, M. Brennan
20033 citations
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Vaccines for sexually transmitted infections: past, present and future.
U. Fruth, N. Broutet, C. Deal, B. Dodet +1 more
2014Vaccine2 citations
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TB VACCINE DEVELOPMENT: A BRIEF BACKGROUND
U. Fruth, J. Pacheco
20142 citations
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The T cell specific serine proteinase TSP-1: biochemical characterization, genetic analysis, and functional role.
H. Simon, U. Fruth, R. Geiger, M. Kramer +1 more
1988Advances in Experimental Medicine and Biology2 citations
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The Analysis of the Function and Specificity of T Cells Triggered During Infection with Leishmania , Its Importance for the Rational Design of a Vaccine
J. Louis, U. Fruth, J. Rosat, F. Conceição-Silva +4 more
19931 citations
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AIDS Vaccine Conference 2013 Busch Vaccine Induced Antibodies Impact for HIV Diagnosis
H. Zinszner, Yegor Voronin, M. Allen, M. Busch +7 more
20150 citations
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Joel Vaccination with Mycobacterium bovis BCG following Primary but Not Secondary In Vitro Inhibition of Mycobacterial Growth
H. Fletcher, R. Tanner, R. Wallis, J. Meyer +12 more
20130 citations
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Vaccine-Induced Antibodies: Impact for HIV Diagnosis, Clinical Trial Participants and Public Health
H. Zinszner, Yegor Voronin, M. Allen, M. Busch +7 more
20130 citations
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Planificar las mejoras de la salud mundial: la lucha antituberculosa en la próxima década
D. Maher, Chris Dye, Katherine Floyd, A. Pantoja +10 more
20070 citations
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Michael D. Kramer

×4

M. Prester×4

M. Kramer×4

J. Thole×3

D. Hoft×3

Yegor Voronin×3

H. Zinszner×3

P. Fast×3