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Nandakumar Packiriswamy · SciRah

Researcher profile · Semantic Scholar

Nandakumar Packiriswamy

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Nandakumar Packiriswamy — researcher profile on SciRah

h-index: 13
Works: 54
Citations: 647

Most-cited papers

Oncolytic measles virus therapy enhances tumor antigen-specific T-cell responses in patients with multiple myeloma
Nandakumar Packiriswamy, D. Upreti, Yumei Zhou, Rehan Khan +6 more
2020Leukemia93 citations Open access
Semantic Scholar
Role of endothelial cells in bovine mammary gland health and disease
V. Ryman, Nandakumar Packiriswamy, L. Sordillo
2015Animal Health Research Reviews80 citations
Semantic Scholar
G-protein coupled receptor kinase 5 mediates Lipopolysaccharide-induced NFκB activation in primary macrophages and modulates inflammation in vivo in mice
Sonika Patial, S. Shahi, Y. Saini, Taehyung Lee +5 more
2011Journal of Cellular Physiology57 citations Open access
Semantic Scholar
Clinical activity of single-dose systemic oncolytic VSV virotherapy in patients with relapsed refractory T-cell lymphoma
Joselle M. Cook, K. Peng, T. Witzig, S. Broski +38 more
2022Blood Advances48 citations Open access
Semantic Scholar
G-protein coupled receptor kinases in inflammation and disease
Nandakumar Packiriswamy, N. Parameswaran
2015Genes and Immunity45 citations Open access
Semantic Scholar
A phase I oncolytic virus trial with vesicular stomatitis virus expressing human interferon beta and tyrosinase related protein 1 administered intratumorally and intravenously in uveal melanoma: safety, efficacy, and T cell responses
K. Smith, K. Peng, Jose S. Pulido, A. Weisbrod +19 more
2023Frontiers in Immunology35 citations Open access
Semantic Scholar
Assessment of heavy metal concentrations and associated resistant bacterial communities in bulk and rhizosphere soil of Avicennia marina of Pichavaram mangrove, India
Baskar Balakrishnan, B. Sahu, Jayappriyan Kothilmozhian Ranishree, Arockia Vasanthi Lourduraj +3 more
2017Environmental Earth Sciences29 citations
Semantic Scholar
Apoptosis of Endothelial Cells by 13-HPODE Contributes to Impairment of Endothelial Barrier Integrity
V. Ryman, Nandakumar Packiriswamy, L. Sordillo
2016Mediators of Inflammation27 citations Open access
Semantic Scholar
G-protein coupled receptor kinase-5 mediates inflammation but does not regulate cellular infiltration or bacterial load in polymicrobial sepsis model in mice
Nandakumar Packiriswamy, Taehyung Lee, P. Raghavendra, Haritha Durairaj +2 more
2013Journal of Innate Immunity27 citations Open access
Semantic Scholar
Supplementation of linoleic acid (C18:2n-6) or α-linolenic acid (C18:3n-3) changes microbial agonist-induced oxylipid biosynthesis.
Valerie E. Ryman, Nandakumar Packiriswamy, B. Norby, S. Schmidt +2 more
2017Journal of Dairy Science21 citations Open access
Semantic Scholar
Oxidative stress-induced mitochondrial dysfunction in a normal colon epithelial cell line
Nandakumar Packiriswamy, Kari F Coulson, S. Holcombe, L. Sordillo
2017World Journal of Gastroenterology21 citations Open access
Semantic Scholar
Nonhematopoietic b-Arrestin-1 Inhibits Inflammation in a Murine Model of Polymicrobial Sepsis
D. Sharma, Nandakumar Packiriswamy, Ankit Malik, P. C. Lucas +1 more
201416 citations
Semantic Scholar
Role of myeloid-specific G-protein coupled receptor kinase-2 in sepsis.
Sitaram Parvataneni, B. Gonipeta, Nandakumar Packiriswamy, Taehyung Lee +2 more
2011International Journal of Clinical and Experimental Medicine15 citations
Semantic Scholar
Boosting of SARS-CoV-2 immunity in nonhuman primates using an oral rhabdoviral vaccine
K. Peng, Timothy Carey, Patrycja J. Lech, R. Vandergaast +26 more
2021bioRxiv13 citations Open access
Semantic Scholar
Molecular characterization and computational analysis of the major outer membrane protein (ompH) gene of Pasteurella multocida P52.
R. Singh, K. Tewari, Nandakumar Packiriswamy, S. Marla +1 more
201113 citations
Semantic Scholar
Poly(I:C) priming exacerbates cecal ligation and puncture-induced polymicrobial sepsis in mice
D. Sharma, Ankit Malik, Nandakumar Packiriswamy, Michael D. Steury +1 more
2017Inflammation12 citations Open access
Semantic Scholar
Oncolytic Measles Virotherapy Does Not Legitimize Opposition To Measles Vaccination
S. Russell, D. Babovic-Vuksanovic, A. Bexon, R. Cattaneo +22 more
2019Mayo Clinic proceedings11 citations Open access
Semantic Scholar
Overlapping and distinct roles of GRK5 in TLR2-, and TLR3-induced inflammatory response in vivo
Nandakumar Packiriswamy, Sitaram Parvataneni, N. Parameswaran
2011Cellular Immunology9 citations Open access
Semantic Scholar
Safety and efficacy of neoadjuvant intravesical oncolytic MV-NIS in patients with urothelial carcinoma.
S. Naik, B. Leibovich, T. Miest, S. Bardot +15 more
2022Journal of Clinical Oncology8 citations
Semantic Scholar
Distinct Signature of Oxylipid Mediators of Inflammation during Infection and Asymptomatic Colonization by E. coli in the Urinary Bladder
Nandakumar Packiriswamy, J. Gandy, Sara N. Smith, H. Mobley +2 more
2017Mediators of Inflammation8 citations Open access
Semantic Scholar
Oncolytic Alphaherpesvirus and Myeloid-Tropic Cytomegalovirus Cooperatively Enhance Systemic Antitumor Responses.
Hai-Fei Jiang, Rebecca A. Nace, Emily Ariail, Yejun Ma +7 more
2023Molecular Therapy7 citations Open access
Semantic Scholar
Bacterial Dose-Dependent Role of G Protein-Coupled Receptor Kinase 5 in Escherichia coli-Induced Pneumonia
Nandakumar Packiriswamy, Michael D. Steury, Ian C. McCabe, S. Fitzgerald +1 more
2016Infection and Immunity7 citations Open access
Semantic Scholar
Clinical activity of systemic VSV-IFNβ-NIS oncolytic virotherapy in patients with relapsed refractory T-cell lymphoma.
Joselle M. Cook, K. Peng, S. Geyer, B. Ginos +16 more
20216 citations
Semantic Scholar
Surface-modified measles vaccines encoding oligomeric, prefusion-stabilized SARS-CoV-2 spike glycoproteins boost neutralizing antibody responses to Omicron and historical variants, independent of measles seropositivity
M. Muñoz-Alía, Rebecca A. Nace, Baskar Balakrishnan, Lianwen Zhang +10 more
2024mBio5 citations Open access
Semantic Scholar
Abstract P6-21-03: Phase I trial of intratumoral (IT) administration of a NIS-expressing derivative manufactured from a genetically engineered strain of measles virus (MV)
M.-C. Liu, K. Peng, M. Federspiel, S. Russell +10 more
2019Poster Session Abstracts5 citations
Semantic Scholar
Role of G protein-coupled receptor kinase-6 in Escherichia coli lung infection model in mice.
Taehyung Lee, Nandakumar Packiriswamy, E. Lee, P. C. Lucas +2 more
2017Physiological Genomics5 citations Open access
Semantic Scholar
Intravenously administered LV-169 delivers a functional BCMA-CAR transgene to niche-resident T cells and leads to elimination of disseminated myeloma in MHC-deficient NSG mice
Stephen J. Russell, G. Nenavath, Nandakumar Packiriswamy, Timothy Carey +15 more
2025Blood4 citations
Semantic Scholar
In Vivo Generation of Functional CD19 CAR-T Cells Using a Serum-Stable CD3-Targeted Lentiviral Vector
Karina Krotova, G. Nenavath, Nandakumar Packiriswamy, R. Vandergaast +5 more
2023Blood4 citations Open access
Semantic Scholar
Phase I Trial of Systemic Administration of Vesicular Stomatitis Virus Genetically Engineered to Express NIS and Human Interferon Beta, in Patients with Relapsed or Refractory Multiple Myeloma (MM), Acute Myeloid Leukemia (AML), and T-Cell Neoplasms (TCL)
Joselle M. Cook, K. Peng, B. Ginos, A. Dueck +30 more
2018Blood4 citations Open access
Semantic Scholar
Abstract CT072: First in human (FIH) dose escalation studies of intravenous administration of VSV-IFNβ-NIS (Voyager-V1™) in Stage IV or recurrent endometrial cancer
J. Bakkum-Gamez, M. Block, Nandakumar Packiriswamy, Bethany A. Brunton +8 more
2018Clinical Trials4 citations
Semantic Scholar
Surface-modified measles vaccines encoding oligomeric, fusion-stabilized SARS-CoV-2 spike glycoproteins bypass measles seropositivity, boosting neutralizing antibody responses to omicron and historical variants
M. Muñoz-Alía, Rebecca A. Nace, Baskar Balakrishnan, Lianwen Zhang +9 more
2022bioRxiv2 citations Open access
Semantic Scholar
TCL-461: Clinical Activity of Systemic VSV-IFNβ-NIS Oncolytic Virotherapy in Patients with Relapsed Refractory Hematologic Malignancies
Joselle M. Cook, K. Peng, S. Geyer, A. Dueck +32 more
20212 citations
Semantic Scholar
Lentiviral vectors engineered for direct In Vivo delivery to resting T cells
G. Nenavath, Md. Sharif Hasan, Nainika Ravichandran, Tatenda Kadungure +16 more
2025Blood1 citations
Semantic Scholar
Abstract CT207: Phase I trial of vesicular stomatitis virus expressing human interferon beta and tyrosinase related protein 1 (VSV-IFNb-TYRP1) in metastatic ocular melanoma
Katherine Smith, A. Weisbrod, C. Strand, Jacob Allerd +13 more
2023Cancer Research1 citations
Semantic Scholar
Safety and efficacy of neoadjuvant intravesical oncolytic MV-NIS in patients undergoing radical cystectomy (RC) for urothelial carcinoma but ineligible for neoadjuvant cisplatin-based chemotherapy.
B. Leibovich, T. Miest, P. Young, M. Gonzalgo +16 more
20201 citations
Semantic Scholar
Abstract CT051: Preliminary correlative and clinical data from a first-in-human (FIH) study of the intratumoral (IT) oncolytic virotherapy, Voyager-V1, in patients with solid tumors
S. Powell, M. Patel, J. Merchan, T. Cripe +11 more
2018Clinical Trials1 citations
Semantic Scholar
VSV-IFNβ-NIS intratumoral (IT) injection: A first-in-human (FIH), phase I study of an innovative oncolytic virotherapy, alone and with an anti-PD-L1 antibody, in patients with refractory solid tumors.
S. Powell, M. Patel, J. Merchan, J. Strauss +13 more
2018Annals of Oncology1 citations Open access
Semantic Scholar
Critical involvement of GPCR kinase-5 in E.coli induced pneumonia (INC7P.427)
Nandakumar Packiriswamy, Michael D. Steury, N. Parameswaran
2014Journal of Immunology1 citations
Semantic Scholar
Abstract 150: T-cell specific transcriptional control eliminates CAR-mediated off-target transduction by CD3-retargeted lentiviral vectors, enabling safe in vivo generation of potent αBCMA-CAR T cells.
Karina Krotova, Nandakumar Packiriswamy, Yeashin Gazi, Collin Gwilt +13 more
2026Cancer Research0 citations
Semantic Scholar
Abstract 273: High-avidity reversible engager proteins efficiently redirect the entry of intravenously delivered lentiviral vectors, simplifying the direct in vivo delivery of CAR-T cell therapy.
G. Nenavath, Nandakumar Packiriswamy, Diana Gataulin, Md. Sharif Hasan +21 more
2026Cancer Research0 citations
Semantic Scholar
Phase I Study of Oncolytic Virus VV1 as Monotherapy or in Combination with Avelumab in Patients with Relapsed Refractory Solid Tumors
J. Merchan, Manish R Patel, T. Cripe, M. Old +9 more
2026Cancer Research Communications0 citations Open access
Semantic Scholar
OA-13 Clinical Translation of LV169, a CD3-Targeted Lentiviral Vector for In Vivo Delivery of a BCMACAR Transgene to T Cells in Patients With Multiple Myeloma
Yi Lin, Karina Krotova, Nandakumar Packiriswamy, G. Nenavath +8 more
2026Clinical Lymphoma, Myeloma & Leukemia0 citations
Semantic Scholar
MP15-16 NEOADJUVANT INTRAVESICAL ONCOLYTIC MEASLES IMMUNOTHERAPY FOR BLADDER CANCER
S. Naik, B. Leibovich, Paul Young, S. Bardot +10 more
2025Journal of Urology0 citations
Semantic Scholar
Abstract 7239: Eradication of B cell lymphoma in a mouse model through in vivo transduction of T cells with an aCD19-CAR utilizing a CD3-targeted lentiviral vector
Karina Krotova, G. Nenavath, Nandakumar Packiriswamy, R. Vandergaast +8 more
2024Cancer Research0 citations
Semantic Scholar
Abstract A024: Systemic administration of CD3-redirected lentiviral vector efficiently targets CD19-CAR delivery to human T cells in vivo
Karina Krotova, G. Nenavath, Nandakumar Packiriswamy, R. Vandergaast +11 more
2023Cancer immunology research0 citations
Semantic Scholar
422 Safety and efficacy of neoadjuvant intravesical oncolytic MV-NIS in patients with urothelial carcinoma
T. Miest, B. Leibovich, S. Bardot, P. Young +17 more
2021Journal for ImmunoTherapy of Cancer0 citations Open access
Semantic Scholar
Abstract P190: Safety and efficacy of neoadjuvant intravesical oncolytic MV-NIS in patients with urothelial carcinoma
T. Miest, B. Leibovich, S. Bardot, P. Young +17 more
2021Poster Presentations - Proffered Abstracts0 citations
Semantic Scholar
Abstract CT090: Rational design of an oncolytic virus permits use of interferon beta as a pharmacodynamic marker for clinical application
T. Cripe, J. Bakkum-Gamez, J. Merchan, M. Lacy +13 more
2019Clinical Trials0 citations
Semantic Scholar
T cell responses to tumor associated antigens in multiple myeloma patients treated with MV-NIS, an oncolytic measles virus.
Nandakumar Packiriswamy, D. Upreti, Yumei Zhou, A. Dispenzieri +2 more
20180 citations
Semantic Scholar
T Cell Responses to Tumor Associated Antigens in Multiple Myeloma Patients Treated with MV-NIS, an Oncolytic Measles Virus
Nandakumar Packiriswamy, D. Upreti, Yumei Zhou, A. Dispenzieri +2 more
20170 citations
Semantic Scholar

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