Tamar Sapir

Most-cited papers

Reduction of microtubule catastrophe events by LIS1, platelet‐activating factor acetylhydrolase subunit
Tamar Sapir, M. Elbaum, O. Reiner
1997EMBO Journal317 citations Open access
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Cell-replacement therapy for diabetes: Generating functional insulin-producing tissue from adult human liver cells
Tamar Sapir, Keren Shternhall, I. Meivar-Levy, T. Blumenfeld +12 more
2005Proceedings of the National Academy of Sciences of the United States of America308 citations Open access
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Doublecortin, a stabilizer of microtubules.
D. Horesh, Tamar Sapir, F. Francis, S. Wolf +4 more
1999Human Molecular Genetics279 citations
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Postnatal phenotype and localization of spinal cord V1 derived interneurons
F. J. Alvarez, Philip C. Jonas, Tamar Sapir, R. Hartley +4 more
2005The Journal of comparative neurology252 citations Open access
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DCX, a new mediator of the JNK pathway
Amos Gdalyahu, I. Ghosh, T. Levy, Tamar Sapir +4 more
2004EMBO Journal235 citations Open access
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Increased LIS1 expression affects human and mouse brain development
W. Bi, Tamar Sapir, O. Shchelochkov, Feng Zhang +21 more
2009Nature Genetics223 citations Open access
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Pax6 and Engrailed 1 Regulate Two Distinct Aspects of Renshaw Cell Development
Tamar Sapir, Eric J. Geiman, Zhi Wang, Tomoko Velasquez +5 more
2004Journal of Neuroscience195 citations Open access
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Targeted mutagenesis of Lis1 disrupts cortical development and LIS1 homodimerization
A. Cahana, T. Escámez, R. S. Nowakowski, N. Hayes +8 more
2001Proceedings of the National Academy of Sciences of the United States of America159 citations Open access
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Doublecortin-like kinase controls neurogenesis by regulating mitotic spindles and M phase progression.
Tianzhi Shu, Huang-Chun Tseng, Tamar Sapir, Patrick J. Stern +6 more
2006Neuron151 citations Open access
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Interaction between LIS1 and doublecortin, two lissencephaly gene products.
M. Caspi, R. Atlas, Ayelet Kantor, Tamar Sapir +1 more
2000Human Molecular Genetics149 citations Open access
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Doublecortin mutations cluster in evolutionarily conserved functional domains.
Tamar Sapir, D. Horesh, M. Caspi, R. Atlas +7 more
2000Human Molecular Genetics138 citations
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The evolving doublecortin (DCX) superfamily
O. Reiner, Frédéric M. Coquelle, Bastian Peter, T. Levy +6 more
2006BMC Genomics129 citations Open access
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The formation of sensorimotor circuits.
Martyn D. Goulding, Guillermo M. Lanuza, Tamar Sapir, S. Narayan
2002Current Opinion in Neurobiology125 citations
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Lissencephaly gene (LIS1) expression in the CNS suggests a role in neuronal migration
O. Reiner, U. Albrecht, M. Gordon, K. A. Chianese +7 more
1995Journal of Neuroscience117 citations Open access
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Accurate Balance of the Polarity Kinase MARK2/Par-1 Is Required for Proper Cortical Neuronal Migration
Tamar Sapir, S. Sapoznik, T. Levy, Danit Finkelshtein +4 more
2008Journal of Neuroscience113 citations Open access
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Developmental activities of the complement pathway in migrating neurons
Anna Gorelik, Tamar Sapir, R. Haffner-Krausz, T. Olender +2 more
2017Nature Communications110 citations Open access
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Microtubule dynamics in neuronal morphogenesis
Akira Sakakibara, Ryota Ando, Tamar Sapir, Teruyuki Tanaka
2013Open Biology98 citations Open access
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LIS1 functions in normal development and disease.
O. Reiner, Tamar Sapir
2013Current Opinion in Neurobiology94 citations
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Tau's role in the developing brain: implications for intellectual disability.
Tamar Sapir, M. Frotscher, T. Levy, E. Mandelkow +1 more
2012Human Molecular Genetics90 citations Open access
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The DCX Superfamily 1: Common and Divergent Roles for Members of the Mouse DCX Superfamily
Frédéric M. Coquelle, T. Levy, S. Bergmann, S. Wolf +7 more
2006Cell Cycle71 citations Open access
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LIS1 is a microtubule-associated phosphoprotein.
Tamar Sapir, A. Cahana, Rony Seger, Sergei Nekhai +1 more
1999European Journal of Biochemistry63 citations
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Pancreatic and duodenal homeobox gene 1 induces hepatic dedifferentiation by suppressing the expression of CCAAT/enhancer‐binding protein β
I. Meivar-Levy, Tamar Sapir, S. Gefen-Halevi, Vered Aviv +4 more
2007Hepatology62 citations Open access
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Polarity Regulation in Migrating Neurons in the Cortex
O. Reiner, Tamar Sapir
2009Molecular Neurobiology55 citations
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Antagonistic Effects of Doublecortin and MARK2/Par-1 in the Developing Cerebral Cortex
Tamar Sapir, A. Shmueli, T. Levy, T. Timm +3 more
2008Journal of Neuroscience54 citations Open access
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Ndel1 palmitoylation: a new mean to regulate cytoplasmic dynein activity
A. Shmueli, M. Segal, Tamar Sapir, Ryouhei Tsutsumi +7 more
2010EMBO Journal53 citations Open access
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Site-specific dephosphorylation of doublecortin (DCX) by protein phosphatase 1 (PP1).
A. Shmueli, Amos Gdalyahu, S. Sapoznik, Tamar Sapir +2 more
2006Molecular and cellular neurosciences53 citations
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Shootin1 Acts in Concert with KIF20B to Promote Polarization of Migrating Neurons
Tamar Sapir, T. Levy, Akira Sakakibara, A. Rabinkov +2 more
2013Journal of Neuroscience50 citations Open access
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Lissencephaly 1 linking to multiple diseases
O. Reiner, S. Sapoznik, Tamar Sapir
2007Neuromolecular medicine44 citations
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The HERV-K accessory protein Np9 controls viability and migration of teratocarcinoma cells
S. Chan, Tamar Sapir, Sung-Soo Park, Jean-François Rual +3 more
2019PLoS ONE42 citations Open access
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The Spinal Muscular Atrophy with Pontocerebellar Hypoplasia Gene VRK1 Regulates Neuronal Migration through an Amyloid-β Precursor Protein-Dependent Mechanism
Hadar Vinograd-Byk, Tamar Sapir, L. Cantarero, P. Lazo +6 more
2015Journal of Neuroscience41 citations Open access
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Analysis of lissencephaly-causing LIS1 mutations.
Tamar Sapir, M. Eisenstein, H. Burgess, D. Horesh +6 more
1999European Journal of Biochemistry41 citations Open access
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Heterogeneous nuclear ribonucleoprotein U (HNRNPU) safeguards the developing mouse cortex
Tamar Sapir, Aditya Kshirsagar, Anna Gorelik, T. Olender +5 more
2022Nature Communications39 citations Open access
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The Interactome of Palmitoyl-Protein Thioesterase 1 (PPT1) Affects Neuronal Morphology and Function
Tamar Sapir, Michael Segal, G. Grigoryan, K. Hansson +3 more
2019Frontiers in Cellular Neuroscience39 citations Open access
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A Double Fail-Safe Approach to Prevent Tumorigenesis and Select Pancreatic β Cells from Human Embryonic Stem Cells
Fahd Qadir, Silvia Álvarez-Cubela, Kinsley C. Belle, Tamar Sapir +14 more
2019Stem Cell Reports37 citations Open access
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Protein S Regulates Neural Stem Cell Quiescence and Neurogenesis
K. Zelentsova, Ziv Talmi, G. Abboud-Jarrous, Tamar Sapir +3 more
2017Stem Cells37 citations Open access
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Serping1/C1 Inhibitor Affects Cortical Development in a Cell Autonomous and Non-cell Autonomous Manner
Anna Gorelik, Tamar Sapir, T. Woodruff, O. Reiner
2017Frontiers in Cellular Neuroscience36 citations Open access
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DCXs Phosphorylation by Not Just aNother Kinase (JNK)
O. Reiner, Amos Gdalyahu, I. Ghosh, T. Levy +3 more
2004Cell Cycle35 citations Open access
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HIV-1 Tat interacts with LIS1 protein
N. Epie, T. Ammosova, Tamar Sapir, Y. Voloshin +4 more
2005Retrovirology34 citations Open access
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Human Liver Cells Expressing Albumin and Mesenchymal Characteristics Give Rise to Insulin-Producing Cells
I. Meivar-Levy, Tamar Sapir, Dana Berneman, T. Weissbach +6 more
2011Journal of Transplantation32 citations Open access
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Reversible Cysteine Acylation Regulates the Activity of Human Palmitoyl-Protein Thioesterase 1 (PPT1)
Michal Segal-Salto, Tamar Sapir, O. Reiner
2016PLoS ONE31 citations Open access
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MARK2/Par-1 guides the directionality of neuroblasts migrating to the olfactory bulb.
S. Mejia‐Gervacio, K. Murray, Tamar Sapir, R. Belvindrah +2 more
2012Molecular and cellular neurosciences31 citations Open access
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Interkinetic Nuclear Movement in the Ventricular Zone of the Cortex
O. Reiner, Tamar Sapir, G. Gerlitz
2011Journal of Molecular Neuroscience31 citations
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Using multi-organ culture systems to study Parkinson’s disease
O. Reiner, Tamar Sapir, Arpan Parichha
2020Molecular Psychiatry26 citations Open access
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Abnormal cortical development; towards elucidation of the LIS1 gene product function (review).
O. Reiner, Tamar Sapir
1998International Journal of Molecular Medicine25 citations
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Altered extracellular matrix structure and elevated stiffness in a brain organoid model for disease
Maayan Karlinski Zur, B. Bhattacharya, I. Solomonov, Sivan Ben Dror +11 more
2024bioRxiv23 citations Open access
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Non-cell autonomous and non-catalytic activities of ATX in the developing brain
Raanan Greenman, Anna Gorelik, Tamar Sapir, Jan Baumgart +8 more
2015Frontiers in Neuroscience22 citations Open access
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Proteomics insights into infantile neuronal ceroid lipofuscinosis (CLN1) point to the involvement of cilia pathology in the disease
Michal Segal-Salto, K. Hansson, Tamar Sapir, A. Kaplan +5 more
2017Human Molecular Genetics19 citations
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Protein S Negatively Regulates Neural Stem Cell Self-Renewal through Bmi-1 Signaling
Katya Zelentsova-Levytskyi, Ziv Talmi, G. Abboud-Jarrous, T. Capucha +2 more
2017Frontiers in Molecular Neuroscience18 citations Open access
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Mark/Par-1 marking the polarity of migrating neurons.
O. Reiner, Tamar Sapir
2014Advances in Experimental Medicine and Biology18 citations
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Targeted mutagenesis of Lis 1 disrupts cortical development and LIS 1 homodimerization.
A. Cahana, T. Escámez, R. S. Nowakowski, N. Hayes +8 more
200118 citations
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