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Sing Y. Chew · SciRah

Researcher profile · Semantic Scholar

Sing Y. Chew

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Sing Y. Chew — researcher profile on SciRah

h-index: 39
Works: 127
Citations: 6,949

Most-cited papers

3D neural tissue models: From spheroids to bioprinting.
Pei Zhuang, A. Sun, J. An, Kai-Chua Chee +1 more
2018Biomaterials247 citations Open access
Semantic Scholar
Drug therapies and delivery mechanisms to treat perturbed skin wound healing.
J. Chin, L. Madden, Sing Y. Chew, D. Becker
2019Advanced Drug Delivery Reviews194 citations
Semantic Scholar
Three-dimensional aligned nanofibers-hydrogel scaffold for controlled non-viral drug/gene delivery to direct axon regeneration in spinal cord injury treatment
L. Nguyen, Ming-Yong Gao, Jun-Quan Lin, Wu-Tian Wu +2 more
2017Scientific Reports175 citations Open access
Semantic Scholar
Codelivery of CRISPR-Cas9 and chlorin e6 for spatially controlled tumor-specific gene editing with synergistic drug effects
Shao-Hui Deng, Xiaoxia Li, Shuang Liu, Ji-Feng Chen +4 more
2020Science Advances134 citations Open access
Semantic Scholar
Combining cell sheet technology and electrospun scaffolding for engineered tubular, aligned, and contractile blood vessels.
S. Rayatpisheh, D. Heath, A. Shakouri, Pim-on Rujitanaroj +2 more
2014Biomaterials106 citations
Semantic Scholar
Nanofibrous scaffold-mediated REST knockdown to enhance neuronal differentiation of stem cells.
W. Low, Pim-on Rujitanaroj, Dong-Keun Lee, P. Messersmith +3 more
2013Biomaterials98 citations
Semantic Scholar
Sustained delivery of siRNA/mesoporous silica nanoparticle complexes from nanofiber scaffolds for long-term gene silencing.
C. Pinese, Jun-Quan Lin, U. Milbreta, Ming-Qiang Li +3 more
2018Acta Biomaterialia95 citations Open access
Semantic Scholar
In vitro and in vivo evaluation of an electrospun-aligned microfibrous implant for Annulus fibrosus repair.
M. Gluais, J. Clouet, M. Fusellier, C. Decante +11 more
2019Biomaterials83 citations Open access
Semantic Scholar
Protrusive waves guide 3D cell migration along nanofibers
C. Guetta-Terrier, Pascale Monzo, Jie Zhu, Hong-Yan Long +7 more
2015Journal of Cell Biology82 citations Open access
Semantic Scholar
Nanofibrous nerve conduit‐enhanced peripheral nerve regeneration
Xu Jiang, R. Mi, Ahmet Hōke, Sing Y. Chew
2014Journal of Tissue Engineering and Regenerative Medicine78 citations Open access
Semantic Scholar
A 3D Fiber‐Hydrogel Based Non‐Viral Gene Delivery Platform Reveals that microRNAs Promote Axon Regeneration and Enhance Functional Recovery Following Spinal Cord Injury
Na Zhang, Jun-Quan Lin, V. Lin, U. Milbreta +7 more
2021Advancement of science74 citations Open access
Semantic Scholar
Small-molecule-induced epigenetic rejuvenation promotes SREBP condensation and overcomes barriers to CNS myelin regeneration
Xue-Zhao Liu, Xue-Lian He, Da-Zhuan E. Xin, Xiao-Wen Zhong +30 more
2024Cell67 citations Open access
Semantic Scholar
Nanofiber-mediated microRNA delivery to enhance differentiation and maturation of oligodendroglial precursor cells
Hua-Jia Diao, W. Low, U. Milbreta, Q. R. Lu +1 more
2015Journal of Controlled Release65 citations Open access
Semantic Scholar
Scaffold-Mediated Sustained, Non-viral Delivery of miR-219/miR-338 Promotes CNS Remyelination.
U. Milbreta, Jun-Quan Lin, C. Pinese, William Ong +9 more
2019Molecular Therapy63 citations Open access
Semantic Scholar
Topographical effects on fiber-mediated microRNA delivery to control oligodendroglial precursor cells development
Hua-Jia Diao, W. Low, Q. R. Lu, Sing Y. Chew
2015Biomaterials57 citations Open access
Semantic Scholar
Modulation of cell-cell interactions for neural tissue engineering: Potential therapeutic applications of cell adhesion molecules in nerve regeneration.
Wai Hon Chooi, Sing Y. Chew
2019Biomaterials54 citations Open access
Semantic Scholar
Localized delivery of CRISPR/dCas9 via layer-by-layer self-assembling peptide coating on nanofibers for neural tissue engineering.
Kunyu Zhang, Wai Hon Chooi, Shuang Liu, J. Chin +4 more
2020Biomaterials48 citations Open access
Semantic Scholar
Three-Dimensional Nanofiber Hybrid Scaffold Directs and Enhances Axonal Regeneration after Spinal Cord Injury.
U. Milbreta, L. Nguyen, Hua-Jia Diao, Jun-Quan Lin +4 more
2016ACS Biomaterials Science & Engineering47 citations Open access
Semantic Scholar
Scaffold-mediated non-viral delivery platform for CRISPR/Cas9-based genome editing.
J. Chin, Wai Hon Chooi, Hongxia Wang, William Ong +2 more
2019Acta Biomaterialia44 citations Open access
Semantic Scholar
Biomimicking Fiber Platform with Tunable Stiffness to Study Mechanotransduction Reveals Stiffness Enhances Oligodendrocyte Differentiation but Impedes Myelination through YAP-Dependent Regulation.
William Ong, N. Marinval, Jun-Quan Lin, M. Nai +7 more
2020Small40 citations Open access
Semantic Scholar
Scaffold-mediated sequential drug/gene delivery to promote nerve regeneration and remyelination following traumatic nerve injuries.
William Ong, C. Pinese, Sing Y. Chew
2019Advanced Drug Delivery Reviews40 citations Open access
Semantic Scholar
Biomimicking Fiber Scaffold as an Effective In Vitro and In Vivo MicroRNA Screening Platform for Directing Tissue Regeneration
Na Zhang, U. Milbreta, J. Chin, C. Pinese +8 more
2019Advancement of science38 citations Open access
Semantic Scholar
Polysaccharide electrospun fibers with sulfated poly(fucose) promote endothelial cell migration and VEGF-mediated angiogenesis.
Pim-on Rujitanaroj, R. Aid‐Launais, Sing Y. Chew, C. Le Visage
2014Biomaterials Science38 citations
Semantic Scholar
Neural Cell Membrane-Coated Nanoparticles for Targeted and Enhanced Uptake by Central Nervous System Cells.
Na Zhang, Jun-Quan Lin, Sing Y. Chew
2021ACS Applied Materials and Interfaces37 citations Open access
Semantic Scholar
Mechanotransduction assays for neural regeneration strategies: A focus on glial cells
N. Marinval, Sing Y. Chew
2021APL Bioengineering35 citations Open access
Semantic Scholar
Stimuli-responsive multifunctional glyconanoparticle platforms for targeted drug delivery and cancer cell imaging
Xumeng Wu, Yu-Jia Tan, H. Toh, L. Nguyen +4 more
2017Chemical Science35 citations Open access
Semantic Scholar
Mussel-Inspired Modification of Nanofibers for REST siRNA Delivery: Understanding the Effects of Gene-Silencing and Substrate Topography on Human Mesenchymal Stem Cell Neuronal Commitment.
W. Low, Pim-on Rujitanaroj, Dong-Keun Lee, Jinghao Kuang +3 more
2015Macromolecular Bioscience33 citations Open access
Semantic Scholar
Injectable hydrogels in stroke and spinal cord injury treatment: a review on hydrogel materials, cell–matrix interactions and glial involvement
Po-Hen Lin, Quan Dong, Sing Y. Chew
2021Materials Advances32 citations Open access
Semantic Scholar
The effects of nanofiber diameter and orientation on siRNA uptake and gene silencing.
W. Y. Yau, Hong-Yan Long, Nils C. Gauthier, J. Chan +1 more
2015Biomaterials32 citations
Semantic Scholar
Nanofiber-mediated release of retinoic acid and brain-derived neurotrophic factor for enhanced neuronal differentiation of neural progenitor cells
W. Low, Pim-on Rujitanaroj, Feng Wang, Jun Wang +1 more
2013Drug Delivery and Translational Research31 citations
Semantic Scholar
Microfiber drug/gene delivery platform for study of myelination.
William Ong, Jun-Quan Lin, Marie E. Bechler, Kai Wang +3 more
2018Acta Biomaterialia30 citations Open access
Semantic Scholar
MicroRNAs and their potential therapeutic applications in neural tissue engineering.
L. Nguyen, Hua-Jia Diao, Sing Y. Chew
2015Advanced Drug Delivery Reviews30 citations Open access
Semantic Scholar
Effects of miR-219/miR-338 on microglia and astrocyte behaviors and astrocyte-oligodendrocyte precursor cell interactions
L. Nguyen, William Ong, Kai Wang, Ming-Feng Wang +2 more
2019Neural Regeneration Research28 citations Open access
Semantic Scholar
Modulating neuroinflammation through molecular, cellular and biomaterial‐based approaches to treat spinal cord injury
C. Lee, Wai Hon Chooi, Shi-Yan Ng, Sing Y. Chew
2022Bioengineering & Translational Medicine25 citations Open access
Semantic Scholar
The effects of nanofiber topography on astrocyte behavior and gene silencing efficiency.
Haoqing Cao, Guillaume Marcy, Eyleen L. K. Goh, Feng Wang +2 more
2012Macromolecular Bioscience25 citations
Semantic Scholar
Mechanical Strain Alters Cellular and Nuclear Dynamics at Early Stages of Oligodendrocyte Differentiation
Ekta Makhija, A. Jagielska, Lena Zhu, Alexander C. Bost +4 more
2018Frontiers in Cellular Neuroscience22 citations Open access
Semantic Scholar
Encapsulation of Human Spinal Cord Progenitor Cells in Hyaluronan-Gelatin Hydrogel for Spinal Cord Injury Treatment.
Christy Kwokdinata, V. Ramanujam, Jia-Hui Chen, Paula Nunes de Oliveira +6 more
2023ACS Applied Materials and Interfaces19 citations
Semantic Scholar
Nontoxic, Biodegradable Hyperbranched Poly(β-amino ester)s for Efficient siRNA Delivery and Gene Silencing.
Ying Jie Ooi, Chong-Quan Huang, Kieran Lau, Sing Y. Chew +2 more
2024ACS Applied Materials and Interfaces18 citations
Semantic Scholar
Neural cell membrane-coated DNA nanogels as a potential target-specific drug delivery tool for the central nervous system.
Po-Hen Lin, Chongquan Huang, Yuwei Hu, V. Ramanujam +6 more
2023Biomaterials17 citations
Semantic Scholar
Modulating Macrophage Phenotype by Sustained MicroRNA Delivery Improves Host‐Implant Integration
Jun-Quan Lin, I. Mohamed, Po-Hen Lin, Hitomi Shirahama +7 more
2019Advanced Healthcare Materials17 citations Open access
Semantic Scholar
Regenerative rehabilitation: exploring the synergistic effects of rehabilitation and implantation of a bio-functional scaffold in enhancing nerve regeneration.
Jun-Quan Lin, D. Anopas, U. Milbreta, Po-Hen Lin +6 more
2019Biomaterials Science17 citations Open access
Semantic Scholar
Molecular beacon-loaded polymeric nanoparticles for non-invasive imaging of mRNA expression.
Christian Wiraja, David C. Yeo, Sing Y. Chew, Chen-Jie Xu
2015Journal of materials chemistry. B17 citations
Semantic Scholar
Label-Free and High-Throughput Removal of Residual Undifferentiated Cells From iPSC-Derived Spinal Cord Progenitor Cells
T. Nguyen, Wai Hon Chooi, Hyungkook Jeon, Jiahui Chen +6 more
2023bioRxiv15 citations Open access
Semantic Scholar
Cellular Features Revealed by Transverse Laser Modes in Frequency Domain
Z. Qiao, Hongmei Xu, Na Zhang, Xuerui Gong +5 more
2021Advancement of science15 citations Open access
Semantic Scholar
Localised non-viral delivery of nucleic acids for nerve regeneration in injured nervous systems.
Na Zhang, J. Chin, Sing Y. Chew
2019Experimental Neurology15 citations Open access
Semantic Scholar
Scaffold mediated gene knockdown for neuronal differentiation of human neural progenitor cells.
Wai Hon Chooi, William Ong, Aoife Murray, Jun-Quan Lin +2 more
2018Biomaterials Science15 citations Open access
Semantic Scholar
Polysaccharide nanofibers with variable compliance for directing cell fate.
Xu Jiang, M. Nai, C. Lim, C. Le Visage +2 more
2015Journal of Biomedical Materials Research. Part A15 citations
Semantic Scholar
Brain Cell Laser Powered by Deep‐Learning‐Enhanced Laser Modes
Z. Qiao, Wen Sun, Na Zhang, R. Ang +3 more
2021Advanced Optical Materials14 citations
Semantic Scholar
Biofunctional scaffolds with high packing density of aligned electrospun fibers support neural regeneration.
Vanja Cnops, J. Chin, U. Milbreta, Sing Y. Chew
2020Journal of Biomedical Materials Research. Part A12 citations Open access
Semantic Scholar
Targeting connexin 43 expression via scaffold mediated delivery of antisense oligodeoxynucleotide preserves neurons, enhances axonal extension, reduces astrocyte and microglial activation after spinal cord injury
J. Chin, U. Milbreta, D. L. Becker, Sing Y. Chew
2023Journal of Tissue Engineering11 citations Open access
Semantic Scholar

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Jun-Quan Lin×12
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Jun-Quan Lin — researcher profile on SciRah
U. Milbreta×11
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U. Milbreta — researcher profile on SciRah
J. Chin×10
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J. Chin — researcher profile on SciRah
William Ong×9
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William Ong — researcher profile on SciRah

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Wai Hon Chooi — researcher profile on SciRah

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L. Nguyen — researcher profile on SciRah

Pim-on Rujitanaroj×5

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W. Low — researcher profile on SciRah

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C. Pinese — researcher profile on SciRah

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Wu-Tian Wu — researcher profile on SciRah

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Na Zhang — researcher profile on SciRah

Hua-Jia Diao×4

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Hua-Jia Diao — researcher profile on SciRah