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K. Taskén · SciRah

Researcher profile · Semantic Scholar

K. Taskén

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K. Taskén — researcher profile on SciRah

h-index: 68
Works: 338
Citations: 17K

Most-cited papers

Phenotype, penetrance, and treatment of 133 CTLA-4-insufficient subjects
C. Schwab, Annemarie Gabrysch, P. Olbrich, V. Patiño +77 more
2018Journal of Allergy and Clinical Immunology262 citations Open access
Semantic Scholar
Critical Role of CD2 Co-stimulation in Adaptive Natural Killer Cell Responses Revealed in NKG2C-Deficient Humans
Lisa L. Liu, Johannes Landskron, E. H. Ask, Monika Enqvist +14 more
2016Cell Reports215 citations Open access
Semantic Scholar
Monitoring regulatory T cells in clinical samples: consensus on an essential marker set and gating strategy for regulatory T cell analysis by flow cytometry
S. Santegoets, E. Dijkgraaf, A. Battaglia, P. Beckhove +14 more
2015Cancer Immunology and Immunotherapy202 citations Open access
Semantic Scholar
Molecular Mechanisms for cAMP-Mediated Immunoregulation in T cells – Role of Anchored Protein Kinase A Signaling Units
V. Wehbi, K. Taskén
2016Frontiers in Immunology177 citations Open access
Semantic Scholar
The PI3K p110δ Isoform Inhibitor Idelalisib Preferentially Inhibits Human Regulatory T Cell Function
S. Chellappa, K. Kushekhar, L. A. Munthe, G. Tjønnfjord +3 more
2019Journal of Immunology117 citations Open access
Semantic Scholar
Remodeling of secretory lysosomes during education tunes functional potential in NK cells
J. Goodridge, B. Jacobs, M. Saetersmoen, Dennis Clement +20 more
2019Nature Communications116 citations Open access
Semantic Scholar
Activated regulatory and memory T-cells accumulate in malignant ascites from ovarian carcinoma patients
Johannes Landskron, Ø. Helland, K. M. Torgersen, E. Aandahl +3 more
2015Cancer Immunology and Immunotherapy88 citations Open access
Semantic Scholar
Sensing of HIV-1 by TLR8 activates human T cells and reverses latency
H. Meås, M. Haug, M. Beckwith, Claire Louet +8 more
2020Nature Communications78 citations Open access
Semantic Scholar
Aspirin As Secondary Prevention in Patients With Colorectal Cancer: An Unselected Population-Based Study.
Simer J Bains, M. Mahic, T. Myklebust, M. Småstuen +6 more
2016Journal of Clinical Oncology72 citations
Semantic Scholar
Compartmentalization of cAMP Signaling in Adipogenesis, Lipogenesis, and Lipolysis
M. Rogne, K. Taskén
2014Hormone and Metabolic Research66 citations
Semantic Scholar
Targeting protein–protein interactions in complexes organized by A kinase anchoring proteins
A. Calejo, K. Taskén
2015Frontiers in Pharmacology65 citations Open access
Semantic Scholar
A Phase I/II randomized trial of H56:IC31 vaccination and adjunctive cyclooxygenase-2-inhibitor treatment in tuberculosis patients
S. Jenum, K. Tonby, C. Rueegg, M. Ruhwald +10 more
2021Nature Communications62 citations Open access
Semantic Scholar
Regulatory T cells that co-express RORγt and FOXP3 are pro-inflammatory and immunosuppressive and expand in human pancreatic cancer
S. Chellappa, H. Hugenschmidt, M. Hagness, P. Line +4 more
2016Oncoimmunology58 citations Open access
Semantic Scholar
T-cell co-stimulation through the CD2 and CD28 co-receptors induces distinct signalling responses.
S. Skånland, Kristine Moltu, Torunn Berge, E. Aandahl +1 more
2014Biochemical Journal51 citations Open access
Semantic Scholar
The COX- inhibitor indomethacin reduces Th1 effector and T regulatory cells in vitro in Mycobacterium tuberculosis infection
K. Tonby, I. Wergeland, N. Lieske, D. Kvale +2 more
2016BMC Infectious Diseases40 citations Open access
Semantic Scholar
Spatiotemporal regulation of cAMP signaling controls the human trophoblast fusion
P. Gerbaud, K. Taskén, G. Pidoux
2015Frontiers in Pharmacology39 citations Open access
Semantic Scholar
CD8+ T Cells That Coexpress RORγt and T-bet Are Functionally Impaired and Expand in Patients with Distal Bile Duct Cancer
S. Chellappa, H. Hugenschmidt, M. Hagness, S. Subramani +6 more
2017Journal of Immunology33 citations
Semantic Scholar
Optic Atrophy 1 Controls Human Neuronal Development by Preventing Aberrant Nuclear DNA Methylation
S. Caglayan, A. Hashim, Artur Cieślar-Pobuda, V. Jensen +12 more
2020iScience32 citations Open access
Semantic Scholar
Cyclic nucleotide phosphodiesterases as drug targets
Michy P. Kelly, Viacheslav O. Nikolaev, L. Gobejishvili, C. Lugnier +25 more
2025Pharmacological Reviews31 citations Open access
Semantic Scholar
A protein kinase A-ezrin complex regulates connexin 43 gap junction communication in liver epithelial cells.
Aleksandra R. Dukic, L. Haugen, G. Pidoux, E. Leithe +2 more
2017Cellular Signalling30 citations Open access
Semantic Scholar
Plasma IP-10 Is Increased in Immunological NonResponders and Associated With Activated Regulatory T Cells and Persisting Low CD4 Counts
B. Stiksrud, K. B. Lorvik, D. Kvale, T. Mollnes +4 more
2016Journal of Acquired Immune Deficiency Syndromes30 citations
Semantic Scholar
Multiplexed phosphospecific flow cytometry enables large‐scale signaling profiling and drug screening in blood platelets
Benjamin E. J. Spurgeon, A. Aburima, N. Oberprieler, K. Taskén +1 more
2014Journal of Thrombosis and Haemostasis30 citations Open access
Semantic Scholar
OPA1-anchored PKA phosphorylates perilipin 1 on S522 and S497 in adipocytes differentiated from human adipose stem cells
Marie Rogne, Dinh-Toi Chu, T. Küntziger, M. Mylonakou +2 more
2018Molecular Biology of the Cell28 citations Open access
Semantic Scholar
Activated platelets promote increased monocyte expression of CXCR5 through prostaglandin E2-related mechanisms and enhance the anti-inflammatory effects of CXCL13.
B. Halvorsen, L. Smedbakken, A. Michelsen, M. Skjelland +8 more
2014Atherosclerosis27 citations
Semantic Scholar
Targeting Tuberculosis and HIV Infection-Specific Regulatory T Cells with MEK/ERK Signaling Pathway Inhibitors
N. Lieske, K. Tonby, D. Kvale, A. Dyrhol-Riise +1 more
2015PLoS ONE26 citations Open access
Semantic Scholar
Diversity of intratumoral regulatory T cells in B-cell non-Hodgkin lymphoma
I. Spasevska, Ankush Sharma, C. Steen, S. Josefsson +22 more
2023Blood Advances25 citations Open access
Semantic Scholar
EU-OPENSCREEN: A Novel Collaborative Approach to Facilitate Chemical Biology
P. Brennecke, D. Rasina, Oscar Aubi, Katja Herzog +38 more
2019SLAS discovery : advancing life sciences R & D24 citations Open access
Semantic Scholar
Targeting of type I protein kinase A to lipid rafts is required for platelet inhibition by the 3′,5′‐cyclic adenosine monophosphate‐signaling pathway
Z. Raslan, S. Magwenzi, A. Aburima, K. Taskén +1 more
2015Journal of Thrombosis and Haemostasis24 citations Open access
Semantic Scholar
An in vitro assay for biomarker discovery and dose prediction applied to ibrutinib plus venetoclax treatment of CLL
S. Skånland, A. Cremaschi, Henrik Bendiksen, J. Hermansen +4 more
2019Leukemia23 citations
Semantic Scholar
Single cell profiling of phospho-protein levels in chronic lymphocytic leukemia
I. K. Myhrvold, A. Cremaschi, J. Hermansen, G. Tjønnfjord +3 more
2018OncoTarget23 citations Open access
Semantic Scholar
OPA1 in Lipid Metabolism: Function of OPA1 in Lipolysis and Thermogenesis of Adipocytes
Dinh-Toi Chu, Y. Tao, K. Taskén
2017Hormone and Metabolic Research22 citations Open access
Semantic Scholar
Cryopreservation of primary B cells minimally influences their signaling responses
J. Hermansen, G. Tjønnfjord, L. A. Munthe, K. Taskén +1 more
2018Scientific Reports21 citations Open access
Semantic Scholar
Ezrin-anchored PKA phosphorylates serine 369 and 373 on connexin 43 to enhance gap junction assembly, communication, and cell fusion.
Aleksandra R. Dukic, P. Gerbaud, J. Guibourdenche, B. Thiede +2 more
2017Biochemical Journal21 citations Open access
Semantic Scholar
Ex vivo drug sensitivity screening in multiple myeloma identifies drug combinations that act synergistically
M. Giliberto, D. B. T. Thimiri Govinda Raj, A. Cremaschi, S. Skånland +5 more
2022Molecular Oncology20 citations Open access
Semantic Scholar
Anchored PKA as a gatekeeper for gap junctions
G. Pidoux, K. Taskén
2015Communicative & Integrative Biology20 citations Open access
Semantic Scholar
Enhanced Gut-Homing Dynamics and Pronounced Exhaustion of Mucosal and Blood CD4+ T Cells in HIV-Infected Immunological Non-Responders
K. B. Lorvik, M. H. Meyer-Myklestad, Kushi Kushekar, C. Handeland +7 more
2021Frontiers in Immunology19 citations Open access
Semantic Scholar
A heterozygous germline CD100 mutation in a family with primary sclerosing cholangitis
Xiao-Jun Jiang, A. Bergquist, B. Loescher, G. Venkatesh +11 more
2021Science Translational Medicine19 citations
Semantic Scholar
Phenotypic deconvolution in heterogeneous cancer cell populations using drug screening data
A. Köhn-Luque, E. M. Myklebust, D. Tadele, M. Giliberto +11 more
2022bioRxiv17 citations Open access
Semantic Scholar
Autologous bone marrow Th cells can support multiple myeloma cell proliferation in vitro and in xenografted mice
Dong Wang, Y. Fløisand, C. Myklebust, S. Bürgler +9 more
2017Leukemia17 citations Open access
Semantic Scholar
Immunoregulatory signal networks and tumor immune evasion mechanisms: insights into therapeutic targets and agents in clinical development.
Q. Wei, K. Taskén
2022Biochemical Journal16 citations Open access
Semantic Scholar
B cell signalling pathways—New targets for precision medicine in chronic lymphocytic leukaemia
S. Skånland, L. Karlsen, K. Taskén
2020Scandinavian Journal of Immunology16 citations Open access
Semantic Scholar
Disruption of Phosphodiesterase 3A Binding to SERCA2 Increases SERCA2 Activity and Reduces Mortality in Mice With Chronic Heart Failure
J. Skogestad, Ingrid Albert, K. Hougen, Gustav B. Lothe +21 more
2023Circulation14 citations
Semantic Scholar
Mcl‐1 and Bcl‐xL levels predict responsiveness to dual MEK/Bcl‐2 inhibition in B‐cell malignancies
Katrine Melvold, M. Giliberto, L. Karlsen, Pilar Ayuda-Durán +7 more
2021Molecular Oncology14 citations Open access
Semantic Scholar
C77G in PTPRC (CD45) is no risk allele for ovarian cancer, but associated with less aggressive disease
Johannes Landskron, S. M. Kraggerud, E. Wik, A. Dørum +7 more
2017PLoS ONE14 citations Open access
Semantic Scholar
Spleen tyrosine kinase inhibitors reduce CD40L-induced proliferation of chronic lymphocytic leukemia cells but not normal B cells
A. Parente-Ribes, S. Skånland, S. Bürgler, A. Os +5 more
2016Haematologica14 citations Open access
Semantic Scholar
Functional testing to characterize and stratify PI3K inhibitor responses in chronic lymphocytic leukemia
Yanping Yin, P. Athanasiadis, L. Karlsen, A. Urban +13 more
2022Clinical Cancer Research12 citations Open access
Semantic Scholar
Defective IL-4 signaling in T cells defines severe common variable immunodeficiency.
E. Taraldsrud, B. Fevang, S. Jørgensen, Kristine Moltu +5 more
2017Journal of Autoimmunity12 citations
Semantic Scholar
Immune activation and HIV-specific T cell responses are modulated by a cyclooxygenase-2 inhibitor in untreated HIV-infected individuals: An exploratory clinical trial
Christian Prebensen, M. Trøseid, T. Ueland, A. Dahm +6 more
2017PLoS ONE11 citations Open access
Semantic Scholar
The RIAD peptidomimetic inhibits HIV‐1 replication in humanized NSG mice
Maneesh Singh, Pratibha Singh, D. Vaira, Eirik A. Torheim +3 more
2014European Journal of Clinical Investigation11 citations
Semantic Scholar
A Cell-Based High-Throughput Assay for Gap Junction Communication Suitable for Assessing Connexin 43–Ezrin Interaction Disruptors Using IncuCyte ZOOM
Aleksandra R. Dukic, David W. McClymont, K. Taskén
2017SLAS discovery : advancing life sciences R & D10 citations Open access
Semantic Scholar

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