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A. Coveler · SciRah

Researcher profile · Semantic Scholar

A. Coveler

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A. Coveler — researcher profile on SciRah

h-index: 29
Works: 173
Citations: 5,202

Most-cited papers

Organ Preservation in Patients With Rectal Adenocarcinoma Treated With Total Neoadjuvant Therapy
J. García-Aguilar, S. Patil, M. Gollub, Jin K. Kim +38 more
2022Journal of Clinical Oncology792 citations Open access
Semantic Scholar
Sotorasib in KRAS p.G12C–Mutated Advanced Pancreatic Cancer
J. Strickler, H. Satake, T. George, R. Yaeger +18 more
2022New England Journal of Medicine390 citations Open access
Semantic Scholar
Long-Term Results of Organ Preservation in Patients with Rectal Adenocarcinoma Treated with Total Neoadjuvant Therapy: The Randomized Phase II OPRA Trial
F. Verheij, D. Omer, H. Williams, Sabrina T. Lin +39 more
2023Journal of Clinical Oncology302 citations Open access
Semantic Scholar
Tucatinib plus trastuzumab for chemotherapy-refractory, HER2-positive, RAS wild-type unresectable or metastatic colorectal cancer (MOUNTAINEER): a multicentre, open-label, phase 2 study.
J. Strickler, A. Cercek, S. Siena, T. André +18 more
2023The Lancet Oncology192 citations Open access
Semantic Scholar
Organ Preservation and Survival by Clinical Response Grade in Patients With Rectal Cancer Treated With Total Neoadjuvant Therapy
Hannah M. Thompson, D. Omer, Sabrina T. Lin, Jin K. Kim +19 more
2024JAMA Network Open135 citations Open access
Semantic Scholar
Safety and Outcomes of a Plasmid DNA Vaccine Encoding the ERBB2 Intracellular Domain in Patients With Advanced-Stage ERBB2-Positive Breast Cancer: A Phase 1 Nonrandomized Clinical Trial.
M. L. Disis, K. Guthrie, Y. Liu, A. Coveler +4 more
2022JAMA Oncology87 citations Open access
Semantic Scholar
Pancreas Cancer‐Associated Pain Management
A. Coveler, J. Mizrahi, B. Eastman, S. Apisarnthanarax +3 more
2021The Oncologist74 citations Open access
Semantic Scholar
A Phase 3 Randomized Clinical Trial of Chemotherapy With or Without Algenpantucel-L (HyperAcute-Pancreas) Immunotherapy in Subjects With Borderline Resectable or Locally Advanced Unresectable Pancreatic Cancer
D. B. Hewitt, Nicholas N. Nissen, H. Hatoum, B. Musher +17 more
2020Annals of Surgery73 citations
Semantic Scholar
First data for sotorasib in patients with pancreatic cancer with KRAS p.G12C mutation: A phase I/II study evaluating efficacy and safety
J. Strickler, H. Satake, A. Hollebecque, Y. Sunakawa +16 more
2022Journal of Clinical Oncology37 citations
Semantic Scholar
KRAS Mutation Variants and Co-occurring PI3K Pathway Alterations Impact Survival for Patients with Pancreatic Ductal Adenocarcinomas
Adam Diehl, L. Hannan, D. Zhen, A. Coveler +16 more
2022The Oncologist31 citations Open access
Semantic Scholar
Multi-Epitope-Based Vaccines for Colon Cancer Treatment and Prevention
Lauren R. Corulli, D. Cecil, E. Gad, Marlese R Koehnlein +4 more
2021Frontiers in Immunology31 citations Open access
Semantic Scholar
Survival and organ preservation according to clinical response after total neoadjuvant therapy in locally advanced rectal cancer patients: A secondary analysis from the organ preservation in rectal adenocarcinoma (OPRA) trial.
Hannah M. Thompson, Jin K. Kim, J. Yuval, F. Verheij +16 more
202130 citations
Semantic Scholar
GSK-3β in Pancreatic Cancer: Spotlight on 9-ING-41, Its Therapeutic Potential and Immune Modulatory Properties
R. Park, A. Coveler, L. Cavalcante, A. Saeed
2021Biology26 citations Open access
Semantic Scholar
A Phase Ib/II Randomized Clinical Trial of Oleclumab with or without Durvalumab plus Chemotherapy in Patients with Metastatic Pancreatic Ductal Adenocarcinoma
A. Coveler, M. Reilley, M. Zalupski, T. Macarulla +19 more
2024Clinical Cancer Research25 citations Open access
Semantic Scholar
Phase 1 dose-escalation study of SEA-CD40: a non-fucosylated CD40 agonist, in advanced solid tumors and lymphomas
A. Coveler, David C. Smith, T. Phillips, B. Curti +19 more
2023Journal for ImmunoTherapy of Cancer25 citations Open access
Semantic Scholar
Pembrolizumab with low-dose carboplatin for recurrent platinum-resistant ovarian, fallopian tube, and primary peritoneal cancer: survival and immune correlates
J. Liao, W. Gwin, R. Urban, Katie M. Hitchcock-Bernhardt +13 more
2021Journal for ImmunoTherapy of Cancer23 citations Open access
Semantic Scholar
CodeBreak 100: Activity of AMG 510, a novel small molecule inhibitor of KRASG12C, in patients with advanced colorectal cancer.
M. Fakih, J. Desai, Y. Kuboki, J. Strickler +15 more
202022 citations
Semantic Scholar
LBA-2 Primary analysis of MOUNTAINEER: A phase 2 study of tucatinib and trastuzumab for HER2-positive mCRC
J. Strickler, A. Cercek, S. Siena, T. André +16 more
2022Annals of Oncology19 citations Open access
Semantic Scholar
Immunization with a plasmid DNA vaccine encoding the N-terminus of Insulin like Growth Factor Binding Protein-2 in advanced ovarian cancer leads to high level Type I immune responses
D. Cecil, J. Liao, Y. Dang, A. Coveler +5 more
2021Clinical Cancer Research14 citations Open access
Semantic Scholar
Tucatinib plus trastuzumab for chemotherapy-refractory, HER2 + , RAS wild-type metastatic colorectal cancer (MOUNTAINEER): final analysis
J. Strickler, A. Cercek, S. Siena, T. André +19 more
2026Nature Communications13 citations Open access
Semantic Scholar
Phase II study of PEGPH20 plus pembrolizumab for patients (pts) with hyaluronan (HA)-high refractory metastatic pancreatic adenocarcinoma (mPC): PCRT16-001.
D. Zhen, Martin C. Whittle, P. Ritch, H. Hochster +12 more
2022Journal of Clinical Oncology13 citations
Semantic Scholar
Biomarkers of pembrolizumab efficacy in advanced anal squamous cell carcinoma: analysis of a phase II clinical trial and a cohort of long-term responders
B. Huffman, Harshabad Singh, Lestat R. Ali, N. Horick +34 more
2024Journal for ImmunoTherapy of Cancer12 citations Open access
Semantic Scholar
LBA27 Additional analyses of MOUNTAINEER: A phase II study of tucatinib and trastuzumab for HER2-positive mCRC
J. Strickler, A. Cercek, S. Siena, T. André +16 more
2022Annals of Oncology11 citations Open access
Semantic Scholar
Feasibility of wide detector CT perfusion imaging performed during routine staging and restaging of pancreatic ductal adenocarcinoma
Ryan B. O'Malley, Erik V. Soloff, A. Coveler, Danielle Cox +4 more
2020Abdominal Radiology9 citations
Semantic Scholar
546 A phase I dose escalation study of STEMVAC, a multi-antigen, multi-epitope Th1 selective plasmid-based vaccine, targeting stem cell associated proteins in patients with advanced breast cancer
M. Disis, Ying Liu, S. Stanton, W. Gwin +4 more
2022Regular and Young Investigator Award Abstracts8 citations Open access
Semantic Scholar
Phase II study of elraglusib (9-ING-41), a GSK-3β inhibitor, in combination with gemcitabine plus nab-paclitaxel in previously untreated metastatic pancreatic cancer
D. Mahalingam, A. Saeed, S. Powell, M. Huerta +16 more
2025ESMO Open7 citations Open access
Semantic Scholar
Final results of a phase 2 study of tucatinib and trastuzumab for HER2-positive mCRC (MOUNTAINEER).
J. Strickler, A. Cercek, S. Siena, Thierry Andre +16 more
2024Journal of Clinical Oncology7 citations Open access
Semantic Scholar
Use of acupuncture with acupressure in addition to standard-of-care cryotherapy to decrease chemotherapy-associated neuropathy in patients with gastrointestinal malignancies receiving oxaliplatin-based chemotherapy: Study protocol for a randomized, controlled pilot and feasibility study
Stacey A. Cohen, Susan Veleber, J. Siman, K. Guthrie +19 more
2023Contemporary Clinical Trials7 citations Open access
Semantic Scholar
Updated results of a phase 1 study of SEA-CD40, gemcitabine, nab-paclitaxel, and pembrolizumab in patients with metastatic pancreatic ductal adenocarcinoma (PDAC; SGNS40-001).
A. Coveler, M. Gutierrez, G. Vaccaro, U. Brown-Glaberman +9 more
2023Journal of Clinical Oncology7 citations Open access
Semantic Scholar
HER2 testing in the MOUNTAINEER trial: Analysis of treatment response based on central HER2 assessment using IHC/ISH and NGS.
J. Strickler, A. Cercek, K. Ng, S. Siena +16 more
2023Journal of Clinical Oncology7 citations Open access
Semantic Scholar
114P Prospective longitudinal tumor-informed ctDNA in resectable biliary tract cancers
G. King, S. A. Cohen, E. Chiorean, W. P. Harris +8 more
2023Annals of Oncology7 citations Open access
Semantic Scholar
A Phase I/II trial of HER-2/neu vaccine primed autologous T-cell infusions in patients with treatment refractory HER-2/neu overexpressing breast cancer
M. Disis, Y. Dang, A. Coveler, J. Childs +5 more
2023Clinical Cancer Research7 citations Open access
Semantic Scholar
A phase Ib study of NUC-3373 in combination with standard therapies in advanced/metastatic colorectal cancer (NuTide:302).
A. Coveler, F. Kazmi, K. Ciombor, J. Graham +5 more
20217 citations
Semantic Scholar
Phase II Study of Pegvorhyaluronidase Alfa (PEGPH20) and Pembrolizumab for Patients with Hyaluronan-High, Pretreated Metastatic Pancreatic Ductal Adenocarcinoma: PCRT16-001
E. Chiorean, Sheela R. Damle, D. Zhen, Martin C. Whittle +15 more
2026Cancers6 citations
Semantic Scholar
Phase 1 study of Elraglusib (9-ING-41), a glycogen synthase kinase-3b inhibitor, as monotherapy or combined with chemotherapy in patients with advanced malignancies.
B. Carneiro, L. Cavalcante, D. Mahalingam, A. Saeed +22 more
2023Clinical Cancer Research6 citations
Semantic Scholar
Phase I study of SEA-CD40, gemcitabine, nab-paclitaxel, and pembrolizumab in patients with metastatic pancreatic ductal adenocarcinoma (PDAC).
A. Coveler, D. Bajor, A. Masood, E. Yilmaz +9 more
20206 citations
Semantic Scholar
PCRT16-001: Phase II study of PEGPH20 plus pembrolizumab for patients (pts) with hyaluronan (HA)-high refractory metastatic pancreatic ductal adenocarcinoma (mPDA).
E. Chiorean, P. Ritch, D. Zhen, E. Poplin +9 more
20206 citations
Semantic Scholar
A Phase II Study of Denileukin Diftitox in Patients with Advanced Treatment Refractory Breast Cancer
W. Gwin, L. G. Salazar, James Y. Dai, D. Higgins +8 more
2025Vaccines5 citations Open access
Semantic Scholar
Exercise Guidelines in Pancreatic Cancer Based on the Dietz Model
Philip J. Chang, A. Hendifar, G. Gresham, A. Ngo-Huang +3 more
2025Cancers5 citations Open access
Semantic Scholar
Phase I study of autologous transgenic T cells expressing high affinity mesothelin-specific T-cell receptor (TCR; FH-TCR TMSLN) in patients with metastatic pancreatic ductal adenocarcinoma (mPDA).
E. Chiorean, A. Chapuis, A. Coveler, Cecilia C. S. Yeung +11 more
2023Journal of Clinical Oncology5 citations
Semantic Scholar
Safety and clinical activity of oleclumab (O) ± durvalumab (D) + chemotherapy (CT) in patients (pts) with metastatic pancreatic ductal adenocarcinoma (mPDAC): A phase 1b/2 randomized study.
A. Coveler, M. Reilley, M. Zalupski, T. Macarulla +16 more
2023Journal of Clinical Oncology5 citations
Semantic Scholar
Leveraging patient‐reported outcomes (PROs) in patients with pancreatic cancer: The Pancreatic Cancer Action Network (PanCAN) online patient registry experience
Arjun Gupta, O. Khalid, C. Moravek, Anica Lamkin +8 more
2021Cancer Medicine5 citations Open access
Semantic Scholar
Rezatapopt, a selective p53 reactivator, in advanced or metastatic solid tumours with a TP53 Y220C mutation: interim efficacy results from patients with ovarian cancer in the phase 2 PYNNACLE trial
J. Frenel, E. Dumbrava, A. Italiano, A. Fagotti +15 more
2026International Journal of Gynecological Cancer4 citations
Semantic Scholar
Preliminary results from the randomized phase 2 study (1801 part 3B) of elraglusib in combination with gemcitabine/nab-paclitaxel (GnP) versus GnP alone in patients (pts) with previously untreated metastatic pancreatic ductal adenocarcinoma (mPDAC).
D. Mahalingam, R. Shroff, B. Carneiro, Yan Ji +16 more
2025Journal of Clinical Oncology4 citations Open access
Semantic Scholar
A multicenter phase Ia study of AbGn-107, a novel antibody–drug conjugate, in patients with advanced gastrointestinal cancer
Andrew H. Ko, A. Coveler, Benjamin L. Schlechter, T. Bekaii-Saab +8 more
2024Investigational new drugs4 citations
Semantic Scholar
Abstract P2-02-02: Phase I trial of the safety and immunogenicity of a tri-antigen vaccine targeting HER2, IGFBP-2, and IGF-IR in patients with non-metastatic breast cancer
S. Stanton, Kari B. Wisinski, W. Gwin, A. Coveler +12 more
2023Cancer Research4 citations
Semantic Scholar
A phase II study of concurrent WOKVAC vaccination with neoadjuvant chemotherapy and HER2-targeted monoclonal antibody therapy.
W. Gwin, Kristin Kuano, J. Childs, Lynn K Symonds +4 more
2023Journal of Clinical Oncology4 citations
Semantic Scholar
CT perfusion as a potential biomarker for pancreatic ductal adenocarcinoma during routine staging and restaging
Ryan B. O'Malley, Danielle Cox, Erik V. Soloff, Mladen Zečević +4 more
2022Abdominal Radiology4 citations
Semantic Scholar
Elraglusib and chemotherapy in metastatic pancreatic ductal adenocarcinoma: a randomized controlled phase 2 trial
D. Mahalingam, R. Shroff, B. Carneiro, Yan Ji +20 more
2026Nature Medicine3 citations Open access
Semantic Scholar
Phase I study of autologous CD8+ and CD4+ transgenic T cells expressing high-affinity KRAS G12V mutation-specific T cell receptors (FH-A11KRASG12V-TCR) in patients with metastatic pancreatic, colorectal, and non-small cell lung cancers with KRAS G12V mutations.
Rachael A Safyan, M. Redman, A. Coveler, Stacey A. Cohen +6 more
2025Journal of Clinical Oncology3 citations
Semantic Scholar

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D. Bajor×10
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D. Bajor — researcher profile on SciRah
J. Strickler×9
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J. Strickler — researcher profile on SciRah
J. Childs×9
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J. Childs — researcher profile on SciRah
A. Cercek×8
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A. Cercek — researcher profile on SciRah

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E. Chiorean — researcher profile on SciRah

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M. Disis — researcher profile on SciRah

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K. Ciombor — researcher profile on SciRah

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A. Kardosh — researcher profile on SciRah