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Jothilingam Sivapackiam · SciRah

Researcher profile · Semantic Scholar

Jothilingam Sivapackiam

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Jothilingam Sivapackiam — researcher profile on SciRah

h-index: 11
Works: 28
Citations: 340

Most-cited papers

Blocking CHOP-dependent TXNIP shuttling to mitochondria attenuates albuminuria and mitigates kidney injury in nephrotic syndrome
Sun-Ji Park, Yeawon Kim, Chuang Li, Junwoo Suh +7 more
2022Proceedings of the National Academy of Sciences of the United States of America67 citations Open access
Semantic Scholar
MANF stimulates autophagy and restores mitochondrial homeostasis to treat autosomal dominant tubulointerstitial kidney disease in mice
Yeawon Kim, Chuang Li, Chen-Jian Gu, Yili Fang +15 more
2023Nature Communications58 citations Open access
Semantic Scholar
A Generator-Produced Gallium-68 Radiopharmaceutical for PET Imaging of Myocardial Perfusion
V. Sharma, Jothilingam Sivapackiam, Scott E. Harpstrite, Julie L. Prior +3 more
2014PLoS ONE31 citations Open access
Semantic Scholar
68Ga-Galmydar: A PET imaging tracer for noninvasive detection of Doxorubicin-induced cardiotoxicity
Jothilingam Sivapackiam, S. Kabra, Sylvia Speidel, Monica Sharma +4 more
2019PLoS ONE24 citations Open access
Semantic Scholar
Galuminox: Preclinical validation of a novel PET tracer for non-invasive imaging of oxidative stress in vivo
Jothilingam Sivapackiam, Fuyi Liao, Dequan Zhou, K. Shoghi +3 more
2020Redox Biology21 citations Open access
Semantic Scholar
Synthesis, molecular structure, and validation of metalloprobes for assessment of MDR1 P-glycoprotein-mediated functional transport.
Jothilingam Sivapackiam, Scott E. Harpstrite, Julie L. Prior, Hannah Gu +2 more
2010Dalton Transactions21 citations
Semantic Scholar
Targeted therapy to β3 integrin reduces chemoresistance in breast cancer bone metastases
Gregory C Fox, Xinming Su, Jennifer L Davis, Yalin Xu +18 more
2021Molecular Cancer Therapeutics20 citations Open access
Semantic Scholar
Synthesis of Dinitro-Substituted Furans, Thiophenes, and Azoles
A. Katritzky, A. V. Vakulenko, Jothilingam Sivapackiam, B. Draghici +1 more
200820 citations
Semantic Scholar
Pseudomonas aeruginosa infection induces intragraft lymphocytotoxicity that triggers lung transplant antibody-mediated rejection
Fuyi Liao, De-Quan Zhou, M. Cano, Zhiyi Liu +12 more
2025Science Translational Medicine19 citations Open access
Semantic Scholar
67/68Galmydar: A Metalloprobe for Monitoring Breast Cancer Resistance Protein (BCRP)-Mediated Functional Transport Activity
Jothilingam Sivapackiam, Scott E. Harpstrite, Julie L. Prior, S. Mattingly +1 more
2015Nuclear Medicine and Biology14 citations
Semantic Scholar
PET Radiopharmaceuticals for Imaging Chemotherapy-Induced Cardiotoxicity
Jothilingam Sivapackiam, Monica Sharma, T. Schindler, V. Sharma
2020Current Cardiology Reports13 citations Open access
Semantic Scholar
Targeted chemotherapy in drug-resistant tumors, noninvasive imaging of P-glycoprotein-mediated functional transport in cancer, and emerging role of Pgp in neurodegenerative diseases.
Jothilingam Sivapackiam, S. Gammon, Scott E. Harpstrite, V. Sharma
2010Methods in molecular biology10 citations
Semantic Scholar
Synthesis, characterization, and preclinical validation of a PET radiopharmaceutical for interrogating Aβ (β-amyloid) plaques in Alzheimer’s disease
G. S. Sundaram, Dhruva D. Dhavale, Julie L. Prior, Jothilingam Sivapackiam +3 more
2015EJNMMI Research9 citations Open access
Semantic Scholar
Coral Microbiomes and Biofilms: Ecological Features, Response to Microbial Infections, and Conservation Strategies
Shanmathi Ravichandran, Desika Thangarasu, Anand Ravichandran, Sridhar Dorai +3 more
2025Marine Ecology3 citations
Semantic Scholar
68Ga[Ga]-Galmydar: Biodistribution and radiation dosimetry studies in rodents.
Jothilingam Sivapackiam, R. Laforest, V. Sharma
2017Nuclear Medicine and Biology3 citations
Semantic Scholar
67Ga-metalloprobes: monitoring the impact of geometrical isomers on accumulation profiles in rat cardiomyoblasts and human breast carcinoma cells.
Jothilingam Sivapackiam, Scott E. Harpstrite, N. Rath, V. Sharma
2017MedChemComm3 citations Open access
Semantic Scholar
Synthesis, characterization, and molecular structure of a novel zinc (II) complex: assessment of impact of MDR1Pgp expression on its cytotoxic activity.
Scott E. Harpstrite, Julie L. Prior, Jothilingam Sivapackiam, S. D. Collins +2 more
2010Medicinal chemistry3 citations
Semantic Scholar
Emerging role of PET/MR in the diagnosis and characterization of cardiotoxicity?
T. Schindler, Jothilingam Sivapackiam, V. Sharma
2023International Journal of Cardiology2 citations
Semantic Scholar
MANF stimulates autophagy and restores mitochondrial homeostasis to treat toxic proteinopathy
Yeawon Kim, Chuang Li, C. Gu, Eric Tycksen +15 more
2023bioRxiv1 citations Open access
Semantic Scholar
Abstract 4369229: Validation of a Novel Reactive Oxygen Species-Targeted SPECT Tracer 67 Ga-Galuminox in Pig Model of Myocardial Ischemia-Reperfusion Injury
Sun-Joo Jang, Jothilingam Sivapackiam, Stephanie Thorn, M. Nazari +6 more
2025Circulation0 citations
Semantic Scholar
Mesencephalic Astrocyte-Derived Neurotrophic Factor (MANF) Stimulates Autophagy and Restores Mitochondrial Homeostasis to Treat Uromodulin-Associated Nephropathy
Chuang Li, Yeawon Kim, Chen-Jian Gu, Yi-Li Fang +15 more
2023Journal of the American Society of Nephrology0 citations
Semantic Scholar
Discovery of a Novel Autophagy Activator to Treat Autosomal Dominant Tubulointerstitial Kidney Disease
Yeawon Kim, Chuang Li, Chen-Jian Gu, Eric Tycksen +14 more
2022Journal of the American Society of Nephrology0 citations
Semantic Scholar
68Ga-Galuminox: A Potential PET Tracer for Imaging ROS-Mediated Activity
Jothilingam Sivapackiam, R. Laforest, R. Gropler, K. Shoghi +2 more
20200 citations
Semantic Scholar
Ga-metalloprobes : monitoring the impact of geometrical isomers on accumulation profiles in rat cardiomyoblasts and human breast carcinoma cells †
Jothilingam Sivapackiam, Scott E. Harpstrite, Nigam P. Rathb, V. Sharma
20170 citations
Semantic Scholar
Structure-Activity Relationship Studies of Novel PET/SPECT Metalloprobes for Myocardial Perfusion Imaging
Jothilingam Sivapackiam, Scott E. Harpstrite, Hannah Gu, Julie L. Prior +1 more
20150 citations
Semantic Scholar
Novel 67/68Gallium-metalloprobe for monitoring functional expression of BCRP
Jothilingam Sivapackiam, Scott E. Harpstrite, V. Sharma
20130 citations
Semantic Scholar
SPECT metalloprobes for monitoring MDR1 P-glycoprotein-mediated transport at the blood-brain barrier
Jothilingam Sivapackiam, Scott E. Harpstrite, Julie L. Prior, D. Piwnica-Worms +1 more
20100 citations
Semantic Scholar
Synthesis of Dinitro-Substituted Furans, Thiophenes, and Azoles.
A. Katritzky, A. V. Vakulenko, Jothilingam Sivapackiam, B. Draghici +1 more
20080 citations
Semantic Scholar

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