Frédéric Burdet

Most-cited papers

1. Endogenous RNAs modulate microRNA sorting to exosomes and transfer to acceptor cells.

   M. Squadrito, Caroline Baer, Frédéric Burdet, Claudio Maderna +4 more

   2014Cell Reports569 citations Open access

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2. The mitophagy activator urolithin A is safe and induces a molecular signature of improved mitochondrial and cellular health in humans

   P. Andreux, W. Blanco-Bose, D. Ryu, Frédéric Burdet +5 more

   2019Nature Metabolism547 citations Open access

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3. Genome-wide profiling of the cardiac transcriptome after myocardial infarction identifies novel heart-specific long non-coding RNAs

   S. Ounzain, R. Micheletti, T. Beckmann, B. Schroen +13 more

   2014European Heart Journal275 citations Open access

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4. Characterization and Functional Identification of a Novel Plant 4,5-Extradiol Dioxygenase Involved in Betalain Pigment Biosynthesis in Portulaca grandiflora

   Laurent Christinet, Frédéric Burdet, Maia Zaiko, U. Hinz +1 more

   2004Plant Physiology180 citations Open access

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5. Systems biology of the IMIDIA biobank from organ donors and pancreatectomised patients defines a novel transcriptomic signature of islets from individuals with type 2 diabetes

   M. Solimena, A. Schulte, L. Marselli, F. Ehehalt +47 more

   2017Diabetologia158 citations Open access

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6. Functional importance of cardiac enhancer-associated noncoding RNAs in heart development and disease

   S. Ounzain, Iole Pezzuto, R. Micheletti, Frédéric Burdet +11 more

   2014Journal of Molecular and Cellular Cardiology126 citations Open access

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7. Multi-omics profiling of living human pancreatic islet donors reveals heterogeneous beta cell trajectories towards type 2 diabetes

   L. Wigger, M. Barovic, Andreas-David Brunner, F. Marzetta +23 more

   2021Nature Metabolism125 citations Open access

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8. A transcribed enhancer dictates mesendoderm specification in pluripotency

   M. Alexanian, D. Maric, Stephen P. Jenkinson, M. Mina +16 more

   2017Nature Communications62 citations Open access

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9. Identification of islet-enriched long non-coding RNAs contributing to β-cell failure in type 2 diabetes

   A. Motterle, S. Gattesco, M. Peyot, J. Esguerra +8 more

   2017Molecular Metabolism59 citations Open access

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10. Discovery and functional characterization of cardiovascular long noncoding RNAs.

    S. Ounzain, Frédéric Burdet, M. Ibberson, T. Pedrazzini

    2015Journal of Molecular and Cellular Cardiology54 citations Open access

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11. A systems genetics resource and analysis of sleep regulation in the mouse

    S. Diessler, Maxime Jan, Y. Emmenegger, N. Guex +11 more

    2018PLoS Biology53 citations Open access

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12. Comparative Genomics Suggests that the Fungal Pathogen Pneumocystis Is an Obligate Parasite Scavenging Amino Acids from Its Host's Lungs

    P. Hauser, Frédéric Burdet, O. Cissé, L. Keller +3 more

    2010PLoS ONE53 citations Open access

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13. Molecular phenotyping of multiple mouse strains under metabolic challenge uncovers a role for Elovl2 in glucose-induced insulin secretion

    C. Cruciani-Guglielmacci, L. Bellini, Jessica Denom, Masaya Oshima +27 more

    2017Molecular Metabolism48 citations Open access

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14. Identification of biomarkers for glycaemic deterioration in type 2 diabetes

    R. Slieker, L. Donnelly, Elina Akalestou, Livia Lopez-Noriega +62 more

    2023Nature Communications39 citations Open access

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15. A Genetic Screen Identifies Hypothalamic Fgf15 as a Regulator of Glucagon Secretion

    A. Picard, Josselin Soyer, Xavier P. Berney, D. Tarussio +6 more

    2016Cell Reports35 citations Open access

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16. Vps13F links bacterial recognition and intracellular killing in Dictyostelium

    Jade Leiba, A. Sabra, Romain Bodinier, Anna Marchetti +8 more

    2017Cellular Microbiology31 citations Open access

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17. Profiling of insulin-resistant kidney models and human biopsies reveals common and cell-type-specific mechanisms underpinning Diabetic Kidney Disease

    Abigail C. Lay, Van Du T. Tran, V. Nair, Virginie M. Betin +21 more

    2024Nature Communications30 citations Open access

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18. An in vitro approach to understand contribution of kidney cells to human urinary extracellular vesicles

    K. Barreiro, A. Lay, G. Leparc, Van Du T. Tran +9 more

    2023Journal of Extracellular Vesicles28 citations Open access

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19. Transcriptional Responses of Dictyostelium discoideum Exposed to Different Classes of Bacteria

    O. Lamrabet, A. Melotti, Frédéric Burdet, N. Hanna +6 more

    2020Frontiers in Microbiology21 citations Open access

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20. Molecular Biomarkers of Neovascular Age-Related Macular Degeneration With Incomplete Response to Anti-Vascular Endothelial Growth Factor Treatment

    I. Mantel, A. Borgo, J. Guidotti, Edwige Forestier +7 more

    2020Frontiers in Pharmacology21 citations Open access

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21. Inferring gene expression networks with hubs using a degree weighted Lasso approach

    Nurgazy Sulaimanov, Sunil Kumar, Frédéric Burdet, M. Ibberson +2 more

    2017Bioinform.19 citations Open access

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22. The SIB Swiss Institute of Bioinformatics Semantic Web of data

    Adrian Amos Parit Delphine Frederic Jerven Alan Frédéric Altenhoff Bairoch Bansal Baratin Bastian Bolleman*, A. Altenhoff, A. Bairoch, Parit Bansal +35 more

    2023Nucleic Acids Research15 citations Open access

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23. Time-resolved RNA-seq profiling of the infection of Dictyostelium discoideum by Mycobacterium marinum reveals an integrated host response to damage and stress

    N. Hanna, Frédéric Burdet, A. Melotti, Cristina Bosmani +5 more

    2019bioRxiv13 citations Open access

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24. Functional recovery of islet β cells in human type 2 diabetes: Transcriptome signatures unveil therapeutic approaches

    M. Suleiman, Toshiaki Sawatani, Marta Tesi, Xiao-Yan Yi +37 more

    2025Science Advances12 citations Open access

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25. Multi-omics profiling of living human pancreatic islet donors reveals heterogeneous beta cell trajectories toward type 2 diabetes

    L. Wigger, M. Barovic, Andreas-David Brunner, F. Marzetta +20 more

    2020bioRxiv12 citations Open access

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26. Association of urinary EGF, FABP3, and VCAM1 levels with the progression of early diabetic kidney disease.

    Felix Keller, Sara Denicolò, Johannes Leierer, Maren Kruus +21 more

    2024Kidney & Blood Pressure Research6 citations Open access

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27. Dictyostelium discoideum flotillin homologues are essential for phagocytosis and participate in plasma membrane recycling and lysosome biogenesis

    Cristina Bosmani, F. Bach, F. Leuba, N. Hanna +4 more

    2019bioRxiv6 citations Open access

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28. Urinary clusterin as a biomarker of human kidney disease progression and response to the endothelin receptor antagonist atrasentan: An exploratory analysis from the SONAR trial

    Wen-Jun Ju, V. Nair, P. Vart, J. D. Smeijer +18 more

    2026Nature Communications5 citations Open access

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29. A Federated Database for Obesity Research: An IMI-SOPHIA Study

    C. Delfin, I. Dragan, D. Kuznetsov, J. F. Tajes +44 more

    2024Life4 citations Open access

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30. Novel biomarkers for glycaemic deterioration in type 2 diabetes: an IMI RHAPSODY study

    R. Slieker, L. Donnelly, Livia Lopez-Noriega, Hermine Muniangi-Muhitu +52 more

    2021medRxiv4 citations Open access

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31. Vacuolins and myosin VII are required for phagocytic uptake and phagosomal membrane recycling in Dictyostelium discoideum

    Cristina Bosmani, F. Leuba, N. Hanna, F. Bach +4 more

    2020Journal of Cell Science4 citations

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32. Prioritization of novel anti-infective stilbene derivatives by combining metabolomic data organization and a stringent 3R-infection model in a knowledge graph

    O. Kirchhoffer, L. Quirós-Guerrero, J. Nitschke, L. Nothias +10 more

    2025RSC Advances3 citations Open access

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33. BALDR: A Web-based platform for informed comparison and prioritization of biomarker candidates for type 2 diabetes mellitus

    A. Lundgaard, Frédéric Burdet, T. Siggaard, D. Westergaard +9 more

    2023PLoS Comput. Biol.2 citations Open access

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34. The mitophagy activator urolithin A is safe and induces a molecular signature of improved mitochondrial and cellular health in humans

    P. Andreux, W. Blanco-Bose, D. Ryu, Frédéric Burdet +5 more

    2019Nature Metabolism2 citations Open access

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35. kgsteward: a tool for building, reproducing and maintaining distributed knowledge graphs

    Marco Pagni, Robin Engler, Frédéric Burdet, Sébastien Moretti +14 more

    20260 citations

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36. Time-resolved transcriptomic profiling of Dictyostelium discoideum infection with Mycobacterium marinum reveals Atg9-dependent restriction via maintenance of vacuole integrity

    J. Nitschke, Justine Toinon, Frédéric Burdet, A. Melotti +5 more

    2026bioRxiv0 citations Open access

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37. Epigenetic landscapes in human pancreatic islets reveal distinct drivers for adaptation to age and type 2 diabetes

    L. Maurin, L. Marselli, M. Boissel, V. Pascat +18 more

    2026Nature Communications0 citations Open access

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38. The insulin/IGF axis is critically important for controlling gene transcription in the podocyte

    J. Hurcombe, Lusyan Dayalan, Fern Barrington, Frédéric Burdet +9 more

    2026bioRxiv0 citations Open access

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39. Enhancing prioritization strategies of natural extracts: integrating heterogeneous data from metabolomics datasets and biological screenings into knowledge graphs

    L. Quiros-Guerrero, Frédéric Burdet, O. Kirchhoffer, P. Haemmerli +16 more

    2025Phytochemistry Letters0 citations

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40. Application of the RDF framework to integrate heterogenous experimental data of a large chemo- and biodiverse collection from a collaborative research project

    Frédéric Burdet, L. Quiros-Guerrero, O. Kirchhoffer, J. Nitschke +16 more

    2024SWAT4HCLS0 citations

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41. Integrative Transcriptome and Proteome Profiling of Insulin-Resistant Kidney Cell Models and Patient Biopsies Reveals Common and Cell Type-Specific Mechanisms Underpinning Diabetic Kidney Disease

    Richard J. M. Coward, Abigail C. Lay, Van Du T. Tran, V. Nair +16 more

    2023Journal of the American Society of Nephrology0 citations

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42. The Insulin/Insulin-Like Growth Factor Axis Is Critically Important in the Kidney Podocyte Controlling Gene Transcription and Spliceosome Function

    J. Hurcombe, Fern Barrington, Frédéric Burdet, P. Brinkkoetter +2 more

    2023Journal of the American Society of Nephrology0 citations

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43. Recovery of human type 2 diabetes beta cell function associates with transcriptomic signatures that point to novel therapeutic targets

    M. Suleiman, Xiao-qing Yi, E. Bosi, Frédéric Burdet +12 more

    20210 citations Open access

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44. Two lipidomics data sources for the publication "Multi-omics profiling of living human pancreatic islet donors reveals heterogeneous beta cell trajectories toward type 2 diabetes"

    L. Wigger, M. Barovic, Andreas-David Brunner, F. Marzetta +23 more

    20210 citations

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45. The transcriptome of persistent or transient human beta cell dys- function caused by lipo-glucotoxicity correlates with the gene expres- sion signature of type 2 diabetic islets

    L. Marselli, M. Suleiman, M. Colli, A. Pocai +11 more

    20190 citations

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46. A transcribed enhancer dictates mesendoderm specification in pluripotency

    M. Alexanian, D. Maric, Stephen P. Jenkinson, M. Mina +16 more

    2017Nature Communications0 citations Open access

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47. Discovery functional characterization of cardiovascular long noncoding RNAs

    S. Ounzain, Frédéric Burdet, M. Ibberson, T. Pedrazzini

    20150 citations

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