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H. Spearman · SciRah

Researcher profile · Semantic Scholar

H. Spearman

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H. Spearman — researcher profile on SciRah

h-index: 14
Works: 21
Citations: 1,020

Most-cited papers

Dok-7 Mutations Underlie a Neuromuscular Junction Synaptopathy
D. Beeson, O. Higuchi, J. Palace, J. Cossins +11 more
2006Science268 citations Open access
Semantic Scholar
Mutation analysis of CHRNA1, CHRNB1, CHRND, and RAPSN genes in multiple pterygium syndrome/fetal akinesia patients.
J. Vogt, B. Harrison, H. Spearman, J. Cossins +5 more
2008American Journal of Human Genetics108 citations Open access
Semantic Scholar
Hypoxia-mediated tumour targeting
K. Binley, Z. Askham, L. Martin, H. Spearman +3 more
2003Gene Therapy93 citations
Semantic Scholar
Long-term reversal of chronic anemia using a hypoxia-regulated erythropoietin gene therapy.
K. Binley, Z. Askham, S. Iqball, H. Spearman +7 more
2002Blood91 citations Open access
Semantic Scholar
FOXP1 suppresses immune response signatures and MHC class II expression in activated B-cell-like diffuse large B-cell lymphomas
P. Brown, K. Wong, S. Felce, L. Lyne +7 more
2015Leukemia74 citations Open access
Semantic Scholar
Characterization of Physiologically Regulated Vectors for the Treatment of Ischemic Disease
K. Boast, K. Binley, S. Iqball, T. Price +4 more
1999Human Gene Therapy70 citations
Semantic Scholar
Mutations Causing DOK7 Congenital Myasthenia Ablate Functional Motifs in Dok-7*
J. Hamuro, O. Higuchi, Kumiko Okada, M. Ueno +5 more
2008Journal of Biological Chemistry67 citations Open access
Semantic Scholar
Diverse molecular mechanisms involved in AChR deficiency due to rapsyn mutations.
J. Cossins, G. Burke, S. Maxwell, H. Spearman +6 more
2006Brain : a journal of neurology58 citations Open access
Semantic Scholar
Direct retroviral delivery of human cytochrome P450 2B6 for gene-directed enzyme prodrug therapy of cancer
O. Kan, L. Griffiths, D. Baban, S. Iqball +9 more
2001Cancer Gene Therapy49 citations Open access
Semantic Scholar
Congenital Myasthenic Syndromes and the Formation of the Neuromuscular Junction
D. Beeson, R. Webster, J. Cossins, D. Lashley +6 more
2008Annals of the New York Academy of Sciences35 citations Open access
Semantic Scholar
The Forkhead Transcription Factor FOXP2 Is Required for Regulation of p21WAF1/CIP1 in 143B Osteosarcoma Cell Growth Arrest
D. Gascoyne, H. Spearman, L. Lyne, R. Puliyadi +5 more
2015PLoS ONE29 citations Open access
Semantic Scholar
Vitamin D Receptor Expression in Plasmablastic Lymphoma and Myeloma Cells Confers Susceptibility to Vitamin D
D. Gascoyne, L. Lyne, H. Spearman, F. Buffa +2 more
2016Endocrinology24 citations Open access
Semantic Scholar
FOXP2-positive diffuse large B-cell lymphomas exhibit a poor response to R-CHOP therapy and distinct biological signatures
K. Wong, D. Gascoyne, E. Soilleux, L. Lyne +6 more
2016OncoTarget22 citations Open access
Semantic Scholar
A novel congenital myasthenic syndrome due to decreased acetylcholine receptor ion-channel conductance.
R. Webster, S. Maxwell, H. Spearman, Kai-Hsu Tai +3 more
2012Brain : a journal of neurology20 citations Open access
Semantic Scholar
N-terminally truncated FOXP1 protein expression and alternate internal FOXP1 promoter usage in normal and malignant B cells
P. Brown, D. Gascoyne, L. Lyne, H. Spearman +8 more
2016Haematologica11 citations Open access
Semantic Scholar
Vitamin D receptor expression in germinal centre type diffuse large B-cell lymphoma cells is associated with vitamin D insensitivity
E. Soilleux, Amanda P. Anderson, Emma Roberts, L. Lyne +5 more
2025Endocrine Oncology0 citations Open access
Semantic Scholar
The Forkhead Transcription Factor FOXP2 Is Required for Regulation of p21 in 143B Osteosarcoma Cell Growth Arrest
D. Gascoyne, H. Spearman, L. Lyne, R. Puliyadi +6 more
20200 citations
Semantic Scholar
Syddansk Universitet FOXP 1 suppresses immune response signatures and MHC class II expression in activated B-cell-like diffuse large B-cell lymphomas
P. Brown, Kk Wong, S. Felce, L. Lyne +6 more
20160 citations
Semantic Scholar
erythropoietin gene therapy Long-term reversal of chronic anemia using a hypoxia-regulated
R. Ali, P. Maxwell, S. Kingsman, S. Naylor +6 more
20130 citations
Semantic Scholar
The NFIL3 transcription factor is preferentially expressed in BCR-independent mature B-cell malignancy
D. Gascoyne, L. Lyne, H. Spearman, E. Soilleux +1 more
20120 citations
Semantic Scholar
M.P.1.04 The effect of dok-7 on acetylcholine receptor clustering in C2C12 cells
H. Spearman, J. Cossins, S. Maxwell, Clarke R. Slater +4 more
20080 citations
Semantic Scholar

Frequent co-authors

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L. Lyne×9
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L. Lyne — researcher profile on SciRah
D. Beeson×7
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D. Beeson — researcher profile on SciRah
D. Gascoyne×7
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A. Banham×6
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J. Cossins — researcher profile on SciRah

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S. Kingsman — researcher profile on SciRah

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E. Soilleux — researcher profile on SciRah

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K. Binley — researcher profile on SciRah

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S. Iqball — researcher profile on SciRah

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