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S. Paston · SciRah

Researcher profile · Semantic Scholar

S. Paston

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S. Paston — researcher profile on SciRah

h-index: 11
Works: 45
Citations: 906

Most-cited papers

Monoclonal TCR-redirected tumor cell killing
N. Liddy, G. Bossi, K. Adams, A. Lissina +31 more
2012Nature Medicine321 citations
Semantic Scholar
Cancer Vaccines, Adjuvants, and Delivery Systems
S. Paston, Victoria A Brentville, P. Symonds, L. Durrant
2021Frontiers in Immunology168 citations Open access
Semantic Scholar
An approved in vitro approach to preclinical safety and efficacy evaluation of engineered T cell receptor anti-CD3 bispecific (ImmTAC) molecules
Jane V. Harper, K. Adams, G. Bossi, D. Wright +22 more
2018PLoS ONE79 citations Open access
Semantic Scholar
Cytochrome c′ from Rhodobacter capsulatus Confers Increased Resistance to Nitric Oxide
R. Cross, J. Aish, S. Paston, R. Poole +1 more
2000Journal of Bacteriology59 citations Open access
Semantic Scholar
Examining the presentation of tumor-associated antigens on peptide-pulsed T2 cells
G. Bossi, A. Gerry, S. Paston, Deborah H. Sutton +2 more
2013Oncoimmunology56 citations Open access
Semantic Scholar
TCRs with Distinct Specificity Profiles Use Different Binding Modes to Engage an Identical Peptide–HLA Complex
C. Coles, R. Mulvaney, S. Malla, A. Walker +20 more
2020Journal of Immunology49 citations Open access
Semantic Scholar
Elimination of Latently HIV-infected Cells from Antiretroviral Therapy-suppressed Subjects by Engineered Immune-mobilizing T-cell Receptors
Hongbing Yang, S. Buisson, G. Bossi, Zoë Wallace +12 more
2016Molecular Therapy47 citations Open access
Semantic Scholar
Progress made towards the development of a CMV peptide vaccine.
S. Paston, I. Dodi, J. Madrigal
2004Human Immunology32 citations
Semantic Scholar
The prevention and treatment of cytomegalovirus infection in haematopoietic stem cell transplantation
M. Tuthill, Frederick Chen, S. Paston, H. De la Peña +2 more
2009Cancer Immunology and Immunotherapy22 citations Open access
Semantic Scholar
PAD-2-mediated citrullination of nucleophosmin provides an effective target for tumor immunotherapy
Ruhul H. Choudhury, P. Symonds, S. Paston, I. Daniels +5 more
2022Journal for ImmunoTherapy of Cancer17 citations Open access
Semantic Scholar
The Clinical and Prognostic Significance of Protein Arginine Deiminases 2 and 4 in Colorectal Cancer
Mohamed Gijon, R. Metheringham, M. Toss, S. Paston +1 more
2021Pathobiology (Basel)11 citations Open access
Semantic Scholar
High affinity soluble ILT2 receptor: a potent inhibitor of CD8+ T cell activation
R. Moysey, Yi Li, S. Paston, Emma Baston +16 more
2010Protein & Cell11 citations Open access
Semantic Scholar
Immune responses to citrullinated and homocitrullinated peptides in healthy donors are not restricted to the HLA SE shared allele and can be selected into the memory pool
Ruhul H. Choudhury, I. Daniels, Poonam M Vaghela, Suha Atabani +11 more
2023Immunology6 citations Open access
Semantic Scholar
Vaccination with post-translational modified, homocitrullinated peptides induces CD8 T-cell responses that mediate antitumor immunity
Sabaria Shah, K. Cook, P. Symonds, J. Weißer +6 more
2023Journal for ImmunoTherapy of Cancer6 citations Open access
Semantic Scholar
What do cancer-specific T cells ‘see’?
Sabaria Shah, Abdullah A. Al-Omari, K. Cook, S. Paston +2 more
2022Discovery Immunology6 citations Open access
Semantic Scholar
Modi-1, anti-citrullinated neoepitope vaccine, alone and combined with checkpoint inhibitors in patients with head and neck, breast, renal, and ovarian cancers: ModiFy phase I/II basket clinical trial—Report after completion of monotherapy dose-finding.
C. Ottensmeier, David J. James Pinato, A. Armstrong, S. Symeonides +8 more
2023Journal of Clinical Oncology5 citations Open access
Semantic Scholar
Abstract 3525: IMCgp100: A novel bi-specific biologic for the treatment of malignant melanoma
N. Hassan, K. Adams, G. Bossi, Jane V. Harper +23 more
20123 citations
Semantic Scholar
SC134-TCB Targeting Fucosyl-GM1, a T Cell–Engaging Antibody with Potent Antitumor Activity in Preclinical Small Cell Lung Cancer Models
Foram Dave, Poonam Vaghela, Bryony Heath, Zuzana Dunster +12 more
2024Molecular Cancer Therapeutics2 citations Open access
Semantic Scholar
ImmTACs: bi-specific TCR-anti-CD3 fusions for targeted tumour killing
Zoe Donnellan, G. Bossi, Jane V. Harper, J. Dukes +11 more
2015Journal of Immunotherapy for Cancer2 citations Open access
Semantic Scholar
Abstract LB214: A DNA plasmid melanoma cancer vaccine, SCIB1, combined with nivolumab + ipilimumab in patients with advanced unresectable melanoma: Efficacy and safety results from the open-label Phase 2 SCOPE Trial
H. Shaw, Poulam Patel, M. Payne, Satish Kumar +16 more
2025Cancer Research1 citations
Semantic Scholar
Abstract CT256: Modi-1, anti-citrullinated neoepitope vaccine alone and combined with checkpoint inhibitors in patients with head and neck, breast, renal and ovarian carcinoma: protocol for the ModiFY phase I/II basket clinical Ttial
L. Durrant, Fayaz Masters, S. Paston, Robert M. Miller +5 more
2023Cancer Research1 citations
Semantic Scholar
Proceedings of the Frontiers in Retrovirology Conference 2018
Wim, Trypsteen, Éva, Malatinkova +27 more
2018Retrovirology1 citations Open access
Semantic Scholar
Novel ImmTAV molecules for the treatment of HBV
T. Laftsoglou, M. Vranas, L. Godinho, J. Long +38 more
20181 citations
Semantic Scholar
Engineered affinity-enhanced immune-mobilising monoclonal T cell receptors (ImmTAVs) for HIV cure
Zoë Wallace, Hongbing Yang, J. Chojnacki, J. Frater +13 more
20171 citations
Semantic Scholar
Abstract 2900: IMCgp100: A novel bi-specific biologic for the treatment of malignant melanoma
N. Hassan, G. Bossi, D. Baker, K. Adams +16 more
20141 citations
Semantic Scholar
Abstract 5616: Soluble, high affinity TCRs fused to anti-CD3 redirect T cells to kill cancer cells presenting MAGE-A3 and NY-ESO antigens
N. Hassan, N. Liddy, T. Mahon, G. Bossi +29 more
20101 citations
Semantic Scholar
Functional Helper T Cell Response to CMV Predicts Probability of CMV Vireamia Following Allogeneic Stem Cell Transplantation.
H. Buyck, S. Paston, M. Lowdell, S. Mackinnon +1 more
20041 citations
Semantic Scholar
Abstract B119: A DNA plasmid melanoma cancer vaccine, SCIB1, combined with nivolumab + ipilimumab induces functional CD4 and CD8 T cell responses in patients with advanced unresectable melanoma
Joe Chadwick, G. Cane, Sabaria Shah, Katie Mann +22 more
2025Cancer immunology research0 citations
Semantic Scholar
The clinical and prognostic significance of Protein Arginine Deiminase 2 and 4 (PADI2 & PADI4) in colorectal cancer
Mohamed Gijon, R. Metheringham, M. Toss, S. Paston +1 more
20200 citations Open access
Semantic Scholar
Abstract A214: An in vitro preclinical package to assess the safety and efficacy of ImmTAC™ molecules
Ana Ribeiro, Tomasz Dobrzycki, Jane V. Harper, G. Bossi +13 more
2019Regulating T-cells and Their Response to Cancer0 citations
Semantic Scholar
Engineering high affinity, soluble T cell receptors for the treatment of cancer
L. Holt, N. Liddy, G. Bossi, Jane V. Harper +13 more
20180 citations
Semantic Scholar
LBP‐001: Epidemiology and risk factors associated with liver cancer in South Africa
A. Kramvis, D. Mak, C. deVilliers, M. Sengayi +36 more
2018Journal of Viral Hepatitis0 citations
Semantic Scholar
Abstract 4872: Developing high affinity, soluble T cell receptors for the treatment of cancer
A. Knox, Fiona Chester, F. Bianchi, Sarah G. Bailey +20 more
20160 citations
Semantic Scholar
Abstract 4873: ImmTACs re-direct the immune system efficiently to eradicate cancer
G. Bossi, R. Kenefeck, C. Boudousquié, Jane V. Harper +11 more
20160 citations
Semantic Scholar
Cancer-specific T cell receptor isolation for cancer immunotherapy
D. Baker, L. Hibbert, L. Weigand, S. Paston +14 more
2015Journal of Immunotherapy for Cancer0 citations Open access
Semantic Scholar
Abstract 670: ImmTACs: Bi-specific TCR-anti-CD3 fusions for potent re-directed killing of cancer cells
G. Bossi, D. Baker, K. Adams, Jane V. Harper +13 more
20140 citations
Semantic Scholar
Abstract 2805: Cancer-specific T cell receptor isolation for cancer immunotherapy
R. Ryan, L. Hibbert, L. Weigand, S. Paston +13 more
20140 citations
Semantic Scholar
126 IMCgp100: A novel bi-specific biologic for the treatment of malignant melanoma
W. Shingler, Jane V. Harper, G. Bossi, D. Barker +13 more
20140 citations
Semantic Scholar
Abstract 3528: IMCmage1: A novel bi-specific biologic re-directing T cells to kill MAGE-A3/A6 presenting cancers
N. Hassan, D. Baker, Jane V. Harper, K. Adams +21 more
20120 citations
Semantic Scholar
Abstract 1787: ImmTACs: Bi-functional reagents for redirected tumour cell killing
S. Paston, R. Ashfield, N. Liddy, G. Bossi +27 more
20110 citations
Semantic Scholar
Bi-specific TCR anti-CD3 fusion for the immunotherapy of malignant melanoma (156.16)
B. Jakobsen, R. Ashfield, G. Bossi, K. Adams +7 more
2011Journal of Immunology0 citations
Semantic Scholar
Abstract 4744: Soluble, high affinity TCRs fused to anti-CD3 redirect T cells to kill cancer cells presenting MAGE-A3 and NY-ESO antigens
Jane V. Harper, N. Hassan, N. Liddy, T. Mahon +32 more
20110 citations
Semantic Scholar
Visualization and Characterisation of Melan A Epitope (25–35)/HLA-A2 Complex by High Affinity Soluble Monoclonal T Cell Receptors (mTCRs)
S. Paston, K. Adams, G. Bossi, N. Liddy +6 more
20070 citations
Semantic Scholar
CMV epitope selection and its use in T cell reconstitution in patients undergoing haematopoietic stem cell transplantation
S. Paston
20060 citations
Semantic Scholar
The role of HLA-B alleles in CMV peptide epitope presentation. Is there a hierarchy in HLA presentation of CMV epitopes: 14th Annual BSHI conference abstracts
S. Paston, I. Dodi, P. Travers, J. Madrigal
20030 citations
Semantic Scholar

Frequent co-authors

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B. Jakobsen×25
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B. Jakobsen — researcher profile on SciRah
G. Bossi×22
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G. Bossi — researcher profile on SciRah
N. Hassan×22
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N. Hassan — researcher profile on SciRah
A. Vuidepot×22
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×17

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Jane V. Harper — researcher profile on SciRah

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N. Liddy — researcher profile on SciRah

Emma Baston×15

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Emma Baston — researcher profile on SciRah

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T. Mahon — researcher profile on SciRah

Andrew Johnson×13

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Andrew Johnson — researcher profile on SciRah

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K. Adams — researcher profile on SciRah

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M. Sami — researcher profile on SciRah

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J. Dukes — researcher profile on SciRah