Adrien Le Thomas

Most-cited papers

1. Cutoff suppresses RNA polymerase II termination to ensure expression of piRNA precursors

   Yung-Chia Ariel Chen, E. Stuwe, Yi-Cheng Luo, Maria Ninova +10 more

   2016Molecules and Cells129 citations Open access

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2. Disruption of IRE1α through its kinase domain attenuates multiple myeloma

   J. Harnoss, Adrien Le Thomas, Anna Shemorry, S. Marsters +34 more

   2018Proceedings of the National Academy of Sciences of the United States of America99 citations Open access

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3. IRE1α Disruption in Triple-Negative Breast Cancer Cooperates with Antiangiogenic Therapy by Reversing ER Stress Adaptation and Remodeling the Tumor Microenvironment

   J. Harnoss, Adrien Le Thomas, M. Reichelt, Ofer Guttman +17 more

   2020Cancer Research86 citations Open access

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4. Decoding non-canonical mRNA decay by the endoplasmic-reticulum stress sensor IRE1α

   Adrien Le Thomas, E. Ferri, S. Marsters, J. Harnoss +13 more

   2021Nature Communications76 citations Open access

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5. Antigen-derived peptides engage the ER stress sensor IRE1α to curb dendritic cell cross-presentation

   Ofer Guttman, Adrien Le Thomas, S. Marsters, D. Lawrence +10 more

   2022Journal of Cell Biology46 citations Open access

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6. Activation of the IRE1 RNase through remodeling of the kinase front pocket by ATP-competitive ligands

   E. Ferri, Adrien Le Thomas, H. Wallweber, E. Day +14 more

   2020Nature Communications38 citations Open access

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7. Pumilio protects Xbp1 mRNA from regulated Ire1-dependent decay

   F. Cairrão, Cristiana C Santos, Adrien Le Thomas, S. Marsters +2 more

   2021Nature Communications31 citations Open access

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8. Noncanonical mRNA decay by the endoplasmic-reticulum stress sensor IRE1α promotes cancer-cell survival

   Adrien Le Thomas, E. Ferri, S. Marsters, J. Harnoss +7 more

   2021bioRxiv10 citations Open access

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9. A framework for piRNA cluster manipulation.

   I. Olovnikov, Adrien Le Thomas, A. Aravin

   2014Methods in molecular biology5 citations

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10. Neuronal regulated Ire1-dependent mRNA decay controls germline differentiation in C. elegans

    Mor Levi-Ferber, Rewayd Shalash, Adrien Le Thomas, Yehuda Salzberg +3 more

    2020bioRxiv1 citations Open access

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11. establishment of a repressive chromatin state Piwi induces piRNA-guided transcriptional silencing and Material Supplemental

    Adrien Le Thomas, Alicia K. Rogers, Alexandre Webster, G. Marinov +5 more

    20131 citations

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12. Antigen-derived peptides directly engage the unfolded-protein sensor IRE1α to curb cross-presentation by dendritic cells

    Ofer Guttman, Adrien Le Thomas, S. Marsters, D. Lawrence +9 more

    2021bioRxiv0 citations Open access

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13. Piwi function and piRNA cluster regulation : Drosophila melanogaster

    Adrien Le Thomas

    20140 citations

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