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D. S. Vinay · SciRah

Researcher profile · Semantic Scholar

D. S. Vinay

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D. S. Vinay — researcher profile on SciRah

h-index: 26
Works: 57
Citations: 4,501

Most-cited papers

Immune evasion in cancer: Mechanistic basis and therapeutic strategies.
D. S. Vinay, E. Ryan, G. Pawelec, Wamidh H. Talib +28 more
2015Seminars in Cancer Biology1,466 citations Open access
Semantic Scholar
Role of 4-1BB in immune responses.
D. S. Vinay, B. Kwon
1998Seminars in Immunology371 citations
Semantic Scholar
4-1BB-mediated immunotherapy of rheumatoid arthritis
S. Seo, Jae H. Choi, Y. H. Kim, W. Kang +5 more
2004Nature Medicine357 citations Open access
Semantic Scholar
Immune Responses in 4-1BB (CD137)-Deficient Mice1
B. Kwon, J. Hurtado, Z. Lee, K. Kwack +6 more
2002Journal of Immunology255 citations Open access
Semantic Scholar
A Broad-Spectrum Integrative Design for Cancer Prevention and Therapy
K. Block, C. Gyllenhaal, Leroy Lowe, A. Amedei +176 more
2015Seminars in Cancer Biology249 citations Open access
Semantic Scholar
4‐1BB‐dependent inhibition of immunosuppression by activated CD4+CD25+ T cells
Beom K. Choi, Jun-Sang Bae, Eun M. Choi, W. Kang +3 more
2004Journal of Leukocyte Biology193 citations Open access
Semantic Scholar
Immunotherapy of Cancer with 4-1BB
D. S. Vinay, B. Kwon
2012Molecular Cancer Therapeutics181 citations Open access
Semantic Scholar
Differences in Gastric Carcinoma Microenvironment Stratify According to EBV Infection Intensity: Implications for Possible Immune Adjuvant Therapy
Michael J. Strong, Guo-Rong Xu, Joseph R. Coco, Carl Baribault +14 more
2013PLoS Pathogens155 citations Open access
Semantic Scholar
4-1BB signaling beyond T cells
D. S. Vinay, B. Kwon
2011Cellular & Molecular Immunology145 citations Open access
Semantic Scholar
4-1BB (CD137), an inducible costimulatory receptor, as a specific target for cancer therapy
D. S. Vinay, B. Kwon
2014BMB Reports126 citations Open access
Semantic Scholar
CD137-Deficient Mice Have Reduced NK/NKT Cell Numbers and Function, Are Resistant to Lipopolysaccharide-Induced Shock Syndromes, and Have Lower IL-4 Responses1
D. S. Vinay, Beom K. Choi, Jun-Sang Bae, W. Kim +2 more
2004Journal of Immunology115 citations Open access
Semantic Scholar
Dual immunoregulatory pathways of 4-1BB signaling
D. S. Vinay, Kiweon Cha, B. Kwon
2006Journal of molecular medicine74 citations
Semantic Scholar
4-1BB-mediated amelioration of experimental autoimmune uveoretinitis is caused by indoleamine 2,3-dioxygenase-dependent mechanisms.
Beom K. Choi, T. Asai, D. S. Vinay, Y. H. Kim +1 more
2006Cytokine69 citations
Semantic Scholar
Evidence That Glycoprotein 96 (B2), a Stress Protein, Functions as a Th2-Specific Costimulatory Molecule1
P. Banerjee, D. S. Vinay, Ajith Mathew, M. Raje +5 more
2002Journal of Immunology64 citations Open access
Semantic Scholar
Blockade of 4-1BB (CD137)/4-1BB ligand interactions increases allograft survival
H. R. Cho, B. Kwon, H. Yagita, S. La +11 more
2004Transplant International55 citations
Semantic Scholar
CD11c+CD8+ T cells: two-faced adaptive immune regulators.
D. S. Vinay, B. Kwon
2010Cellular Immunology45 citations
Semantic Scholar
4-1BB Triggering Ameliorates Experimental Autoimmune Encephalomyelitis by Modulating the Balance between Th17 and Regulatory T Cells
Y. H. Kim, Beom K. Choi, Su-Mi Shin, Chang H. Kim +7 more
2011Journal of Immunology44 citations Open access
Semantic Scholar
Origins and functional basis of regulatory CD11c+CD8+ T cells
D. S. Vinay, Chang H. Kim, Beom K. Choi, B. Kwon
2009European Journal of Immunology39 citations Open access
Semantic Scholar
Effect of human apolipoprotein E genotype on the pathogenesis of experimental ocular HSV-1.
P. Bhattacharjee, D. Neumann, T. Foster, S. Bouhanik +4 more
2008Experimental Eye Research39 citations Open access
Semantic Scholar
The tumour necrosis factor/TNF receptor superfamily: therapeutic targets in autoimmune diseases
D. S. Vinay, B. Kwon
2011Clinical and Experimental Immunology35 citations Open access
Semantic Scholar
Peripheral 4-1BB Signaling Negatively Regulates NK Cell Development through IFN-γ
Beom K. Choi, Y. H. Kim, Chang H. Kim, M. Kim +6 more
2010Journal of Immunology35 citations Open access
Semantic Scholar
Therapeutic potential of anti-CD137 (4-1BB) monoclonal antibodies
D. S. Vinay, B. Kwon
2016Expert opinion on therapeutic targets33 citations
Semantic Scholar
Targeting TNF superfamily members for therapeutic intervention in rheumatoid arthritis.
D. S. Vinay, B. Kwon
2012Cytokine32 citations
Semantic Scholar
Role of endogenous 4‐1BB in the development of systemic lupus erythematosus
D. S. Vinay, Jae H. Choi, J. D. Kim, Beom K. Choi +1 more
2007Immunology32 citations Open access
Semantic Scholar
TNF superfamily: costimulation and clinical applications
D. S. Vinay, B. Kwon
2009Cell Biology International29 citations Open access
Semantic Scholar
4–1BB signal stimulates the activation, expansion, and effector functions of γδ T cells in mice and humans
Seung Joon Lee, Y. H. Kim, Sun-Hee Hwang, Yu I. Kim +3 more
2013European Journal of Immunology27 citations Open access
Semantic Scholar
PDCA Expression by B Lymphocytes Reveals Important Functional Attributes
D. S. Vinay, Chang H. Kim, K. Chang, B. Kwon
2009Journal of Immunology24 citations Open access
Semantic Scholar
Amelioration of Mercury-Induced Autoimmunity by 4-1BB1
D. S. Vinay, J. D. Kim, B. Kwon
2006Journal of Immunology23 citations Open access
Semantic Scholar
Immunotherapy Targeting 4-1BB and Its Ligand
D. S. Vinay, B. Kwon
2006International journal of hematology23 citations
Semantic Scholar
Differential expression and costimulatory effect of 4-1BB (CD137) and CD28 molecules on cytokine-induced murine CD8(+) Tc1 and Tc2 cells.
D. S. Vinay, B. Kwon
1999Cellular Immunology22 citations
Semantic Scholar
A 150‐kDa molecule of macrophage membrane stimulates interleukin‐2 and interferon‐γ production and proliferation of ovalbumin‐specific CD4+ T cells
Javed N. Agrewala, D. S. Vinay, Aneesh Joshi, G. C. Mishra
1994European Journal of Immunology19 citations
Semantic Scholar
Relative abilities of 4-1BB (CD137) and CD28 to co-stimulate the response of cytokine deflected Th1 and Th2 cells.
D. S. Vinay, B. Kwon
1999Immunobiology17 citations
Semantic Scholar
Exposure of a Distinct PDCA-1+ (CD317) B Cell Population to Agonistic Anti-4-1BB (CD137) Inhibits T and B Cell Responses Both In Vitro and In Vivo
D. S. Vinay, Seung Joon Lee, Chang H. Kim, H. S. Oh +1 more
2012PLoS ONE15 citations Open access
Semantic Scholar
Blockade of the 4‐1BB (CD137)/4‐1BBL and/or CD28/CD80/CD86 costimulatory pathways promotes corneal allograft survival in mice
T. Asai, Beom K. Choi, Patrick M. Kwon, W. Kim +4 more
2007Immunology14 citations Open access
Semantic Scholar
Absence of 4 1BB gene function exacerbates lacrimal gland inflammation in autoimmune-prone MRL-Faslpr mice.
D. S. Vinay, J. D. Kim, T. Asai, Beom K. Choi +1 more
2007Investigative Ophthalmology and Visual Science14 citations
Semantic Scholar
Harnessing immune checkpoints for cancer therapy.
D. S. Vinay, B. Kwon
2018Immunotherapy11 citations
Semantic Scholar
Genes, Transcripts and Proteins of CD137 Receptor and Ligand
D. S. Vinay, B. Kwon
200611 citations
Semantic Scholar
Characterization of a novel co-stimulatory molecule: a 155-160kD B cell surface protein provides accessory help to CD4+ T cells to proliferate and differentiate.
D. S. Vinay, M. Raje, G. C. Mishra
1996Molecular Immunology9 citations
Semantic Scholar
Effect of Leukotactin-1 on the Protection In Vivo of Myeloid Progenitor Cells against Cytotoxic Chemotherapeutics
W. Y. Kim, H. Broxmeyer, I. Han, D. Park +3 more
2003Journal of Hematotherapy & Stem Cell Research7 citations
Semantic Scholar
In Vivo 4-1BB Deficiency in Myeloid Cells Enhances Peripheral T Cell Proliferation by Increasing IL-15
Beom K. Choi, Y. H. Kim, Don G. Lee, H. S. Oh +5 more
2015Journal of Immunology6 citations Open access
Semantic Scholar
Changes in gene expression in latent HSV-1-infected rabbit trigeminal ganglia following epinephrine iontophoresis
S. Kang, S. Seo, J. M. Hill, B. Kwon +4 more
2003Current Eye Research6 citations
Semantic Scholar
Immunity in the absence of CD28 and CD137 (4‐1BB) molecules
D. S. Vinay, Godwin O. Wolisi, Kang Y. Yu, Beom K. Choi +1 more
2003Immunology and Cell Biology5 citations
Semantic Scholar
Characterization of Novel Costimulatory Molecules
D. S. Vinay, M. Raje, R. Verma, G. C. Mishra
1995Journal of Biological Chemistry5 citations Open access
Semantic Scholar
Herpesvirus infection of ICAM-1–deficient mice
Hyo-oon Jung, Cho-Rok Jung, Beom K. Choi, D. S. Vinay +3 more
2004Current Eye Research4 citations
Semantic Scholar
M150 Modulates the Costimulatory Signals Delivered by B Cells to T Cells and Enhances Their Ability to Help B Cells
J. Agrewala, S. Suvas, Aneesh Joshi, Archana Bhatnagar +2 more
1998Journal of Interferon and Cytokine Research3 citations
Semantic Scholar
Blockade of 4‐1BB (CD137)/4‐1BB ligand interactions increases allograft survival
H. R. Cho, B. Kwon, H. Yagita, S. La +11 more
20041 citations Open access
Semantic Scholar
Mice Immune Responses in 4-1BB
B. Kwon, J. Hurtado, Z. Lee, K. Kwack +6 more
20021 citations
Semantic Scholar
Abstract 3235: Activation-inducible TNFR family receptor (AITR) signaling mediates the polarization of CD4+T cells into Th1, Th2, and Th17, converts Treg to Teff and eradicates solid tumors
B. Kwon, Seung Joon Lee, Y. H. Kim, Joong-won Lee +2 more
2019Immunology0 citations
Semantic Scholar
Increasing IL-15 Enhances Peripheral T Cell Proliferation by In Vivo 4-1BB Deficiency in Myeloid Cells
Beom K. Choi, Y. H. Kim, Don G. Lee, H. S. Oh +5 more
20150 citations
Semantic Scholar
Modulating the Balance between Th17 and Autoimmune Encephalomyelitis by 4-1BB Triggering Ameliorates Experimental
Beom K. Choi, Sunhye Shin, Chang H. Kim, H. S. Oh +6 more
20110 citations
Semantic Scholar

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