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P. Warne · SciRah

Researcher profile · Semantic Scholar

P. Warne

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P. Warne — researcher profile on SciRah

h-index: 21
Works: 32
Citations: 7,551

Most-cited papers

Phosphatidylinositol-3-OH kinase direct target of Ras
P. Rodriguez-Viciana, P. Warne, R. Dhand, B. Vanhaesebroeck +4 more
1994Nature2,038 citations
Semantic Scholar
Role of phosphoinositide 3-OH kinase in cell transformation and control of the actin cytoskeleton by Ras.
P. Rodriguez-Viciana, P. Warne, A. Khwaja, B. Marte +5 more
1997Cell1,143 citations Open access
Semantic Scholar
Stimulation of p21ras upon T-cell activation
J. Downward, J. Graves, P. Warne, S. Rayter +1 more
1990Nature737 citations
Semantic Scholar
Direct interaction of Ras and the amino-terminal region of Raf-1 in vitro
P. Warne, Pablo Rodrigueza Vician, J. Downward
1993Nature699 citations
Semantic Scholar
Binding of ras to phosphoinositide 3-kinase p110alpha is required for ras-driven tumorigenesis in mice.
Surbhi Gupta, A. R. Ramjaun, P. Haiko, Yi-Hua Wang +6 more
2007Cell549 citations Open access
Semantic Scholar
Regulators of mitotic arrest and ceramide metabolism are determinants of sensitivity to paclitaxel and other chemotherapeutic drugs.
C. Swanton, M. Marani, O. Pardo, P. Warne +9 more
2007Cancer Cell398 citations Open access
Semantic Scholar
p110δ, a novel phosphoinositide 3-kinase in leukocytes
B. Vanhaesebroeck, M. Welham, Kei Kotani, R. Stein +6 more
1997397 citations Open access
Semantic Scholar
R-Ras can activate the phosphoinositide 3-kinase but not the MAP kinase arm of the Ras effector pathways.
B. Marte, P. Rodriguez-Viciana, Stefan Wennström, P. Warne +1 more
1997Current Biology244 citations Open access
Semantic Scholar
P110delta, a novel phosphoinositide 3-kinase in leukocytes.
B. Vanhaesebroeck, M. Welham, Kei Kotani, R. Stein +6 more
1997Proceedings of the National Academy of Sciences of the United States of America225 citations
Semantic Scholar
Reduced NF1 expression confers resistance to EGFR inhibition in lung cancer
E. de Bruin, Catherine F. Cowell, P. Warne, Ming Jiang +16 more
2014Cancer Discovery193 citations Open access
Semantic Scholar
CUTL1 is a target of TGFβ signaling that enhances cancer cell motility and invasiveness
P. Michl, A. R. Ramjaun, O. Pardo, P. Warne +7 more
2005162 citations Open access
Semantic Scholar
PI3K pathway dependencies in endometrioid endometrial cancer cell lines
B. Weigelt, P. Warne, M. Lambros, J. Reis-Filho +1 more
2013Clinical Cancer Research134 citations Open access
Semantic Scholar
Fibroblast Growth Factor 2-Mediated Translational Control of IAPs Blocks Mitochondrial Release of Smac/DIABLO and Apoptosis in Small Cell Lung Cancer Cells
O. Pardo, Adeline Lesay, A. Arcaro, R. Lopes +8 more
2003Molecular and Cellular Biology110 citations Open access
Semantic Scholar
Involvement of MINK, a Ste20 family kinase, in Ras oncogene-induced growth arrest in human ovarian surface epithelial cells.
B. Nicke, J. Bastien, Sophia J. Khanna, P. Warne +12 more
2005Molecules and Cells107 citations Open access
Semantic Scholar
A Role for p38 Stress-Activated Protein Kinase in Regulation of Cell Growth via TORC1
Megan Cully, A. Genevet, P. Warne, Caroline Treins +6 more
2009Molecular and Cellular Biology94 citations Open access
Semantic Scholar
The transcriptional response to Raf activation is almost completely dependent on Mitogen-activated Protein Kinase Kinase activity and shows a major autocrine component.
A. Schulze, B. Nicke, P. Warne, S. Tomlinson +1 more
2004Molecular Biology of the Cell79 citations Open access
Semantic Scholar
Epithelial to Mesenchymal Transition in Madin-Darby Canine Kidney Cells Is Accompanied by Down-regulation of Smad3 Expression, Leading to Resistance to Transforming Growth Factor-β-induced Growth Arrest*
F. J. Nicolás, K. Lehmann, P. Warne, C. Hill +1 more
2003Journal of Biological Chemistry79 citations Open access
Semantic Scholar
RAS signalling through PI3-Kinase controls cell migration via modulation of Reelin expression
E. Castellano, M. Molina-Arcas, Agata Adelajda Krygowska, P. East +3 more
2016Nature Communications65 citations Open access
Semantic Scholar
CUTL1 is a target of TGF(beta) signaling that enhances cancer cell motility and invasiveness.
P. Michl, A. R. Ramjaun, O. Pardo, P. Warne +7 more
2005Cancer Cell40 citations
Semantic Scholar
Exoenzyme S of Pseudomonas aeruginosa is not able to induce apoptosis when cells express activated proteins, such as Ras or protein kinase B/Akt
Anna L. Jansson, L. Yasmin, P. Warne, J. Downward +2 more
2006Cellular Microbiology25 citations
Semantic Scholar
a novel phosphoinositide 3-kinase in leukocytes
B. Vanhaesebroeck, M. Welham, Kei Kotani, R. Stein +6 more
199721 citations
Semantic Scholar
Production of monoclonal antibodies to placental alkaline phosphatase: Preliminary characterisation includes identification of one antibody reactive with routinely fixed histological preparations
H. Durbin, D. Tucker, E. Milligan, L. Bobrow +3 more
1988International journal of cancer. Supplement = Journal international du cancer. Supplement13 citations
Semantic Scholar
Adoptive T cell immunotherapy of MSV-induced tumours in nude mice. Part l. Biology of tumour regression and recurrence
D. Tucker, R. Knight, P. Warne
1983Clinical and Experimental Metastasis2 citations
Semantic Scholar
Adoptive T cell immunotherapy of MSV-induced tumours in nude mice. Part II. Sequential analysis of serum immune complexes and blocking activity in reconstituted mice in relation to tumour biology
D. Tucker, R. Knight, P. Warne
1983Clinical and Experimental Metastasis2 citations
Semantic Scholar
Cancer Therapy : Preclinical PI 3 K Pathway Dependencies in Endometrioid Endometrial Cancer Cell Lines
B. Weigelt, P. Warne, M. Lambros, J. Reis-Filho +1 more
20131 citations
Semantic Scholar
Abstract 4472: PI3K pathway dependencies in endometrioid endometrial cancer.
B. Weigelt, P. Warne, M. Lambros, J. Reis-Filho +1 more
20130 citations
Semantic Scholar
Abstract 4835: Genetic determinants of mTOR inhibitor response in breast and endometrial cancer
B. Weigelt, P. Warne, M. Lambros, J. Reis-Filho +1 more
20120 citations
Semantic Scholar
ANALYSIS OF CELL TRANSFORMATION BY ONCOGENIC RAS USING NOVEL FUNCTIONAL GENOMICS APPROACHES
J. Downward, P. Michl, O. Pardo, B. Nicke +3 more
20050 citations
Semantic Scholar
Fibroblast Growth Factor 2-Mediated Translational Control of IAPs Blocks Mitochondrial Release of Smac/DIABLO and Apoptosis in Small Cell Lung Cancer Cells
O. Pardo, Adeline Lesay, A. Arcaro, R. Lopes +8 more
2004Molecular and Cellular Biology0 citations Open access
Semantic Scholar
current as proteins in normal human T lymphocytes . The growth factor IL-2 activates p 21 ras
J. Graves, J. Downward, M. Izquierdo-Pastor, S. Rayter +2 more
20010 citations
Semantic Scholar
Ras to raf to MAPKK
X. Zhang, P. Warne, P. Viciana, J. Downward +1 more
19930 citations
Semantic Scholar
Fluorescent location of ornithine decarboxylase employing derivatives of the specific inhibitor alpha-difluoromethyl ornithine.
Frank S. Steven, L. A. Williams, P. Warne, D. Tucker
1989Journal of enzyme inhibition (Print)0 citations
Semantic Scholar

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