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Thillai V. Sekar · SciRah

Researcher profile · Semantic Scholar

Thillai V. Sekar

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Thillai V. Sekar — researcher profile on SciRah

h-index: 18
Works: 42
Citations: 1,141

Most-cited papers

Polymer Nanoparticles Mediated Codelivery of AntimiR-10b and AntimiR-21 for Achieving Triple Negative Breast Cancer Therapy
Rammohan Devulapally, Narayana M. Sekar, Thillai V. Sekar, Kira Foygel +3 more
2015ACS Nano236 citations Open access
Semantic Scholar
Therapeutic potential of pterostilbene against pancreatic beta‐cell apoptosis mediated through Nrf2
Elango Bhakkiyalakshmi, D. Shalini, Thillai V. Sekar, P. Rajaguru +2 more
2014British Journal of Pharmacology116 citations Open access
Semantic Scholar
Gemcitabine and Antisense-microRNA Co-encapsulated PLGA-PEG Polymer Nanoparticles for Hepatocellular Carcinoma Therapy
Rammohan Devulapally, Kira Foygel, Thillai V. Sekar, J. Willmann +1 more
2016ACS Applied Materials and Interfaces84 citations Open access
Semantic Scholar
Oxidative stress-mediated cytotoxicity and apoptosis induction by TiO2 nanofibers in HeLa cells.
K. Ramkumar, C. Manjula, G. Gnanakumar, M. Kanjwal +3 more
2012European journal of pharmaceutics and biopharmaceutics76 citations Open access
Semantic Scholar
Folate Receptor Targeted Polymeric Micellar Nanocarriers for Delivery of Orlistat as a Repurposed Drug against Triple Negative Breast Cancer
R. Paulmurugan, Rohith Bhethanabotla, Kaushik Mishra, Rammohan Devulapally +5 more
2015Molecular Cancer Therapeutics66 citations Open access
Semantic Scholar
Targeted nanoparticle delivery of therapeutic antisense microRNAs presensitizes glioblastoma cells to lower effective doses of temozolomide in vitro and in a mouse model
M. Malhotra, Thillai V. Sekar, J. Ananta, Rammohan Devulapally +4 more
2018OncoTarget58 citations Open access
Semantic Scholar
Formulation of Anti-miR-21 and 4-Hydroxytamoxifen Co-loaded Biodegradable Polymer Nanoparticles and Their Antiproliferative Effect on Breast Cancer Cells
Rammohan Devulapally, Thillai V. Sekar, R. Paulmurugan
2015Molecular Pharmaceutics58 citations Open access
Semantic Scholar
Reporter Protein Complementation Imaging Assay to Screen and Study Nrf2 Activators in Cells and Living Animals
K. Ramkumar, Thillai V. Sekar, Kira Foygel, B. Elango +1 more
2013Analytical Chemistry45 citations Open access
Semantic Scholar
Noninvasive optical imaging of nitroreductase gene-directed enzyme prodrug therapy system in living animals
S. Bhaumik, Thillai V. Sekar, J. Depuy, June Klimash +1 more
2011Gene Therapy41 citations Open access
Semantic Scholar
Nrf2 activity as a potential biomarker for the pan-epigenetic anticancer agent, RRx-001
S. Ning, Thillai V. Sekar, J. Scicinski, B. Oronsky +3 more
2015OncoTarget38 citations Open access
Semantic Scholar
Ultrasound-guided delivery of thymidine kinase-nitroreductase dual therapeutic genes by PEGylated-PLGA/PIE nanoparticles for enhanced triple negative breast cancer therapy.
Rammohan Devulapally, Taehwa Lee, Aarohi Barghava-Shah, Thillai V. Sekar +4 more
2018Nanomedicine34 citations Open access
Semantic Scholar
Noninvasive Theranostic Imaging of HSV1-sr39TK-NTR/GCV-CB1954 Dual-Prodrug Therapy in Metastatic Lung Lesions of MDA-MB-231 Triple Negative Breast Cancer in Mice
Thillai V. Sekar, Kira Foygel, Ohad Ilovich, R. Paulmurugan
2014Theranostics29 citations Open access
Semantic Scholar
The impact of oxidative stress on islet transplantation and monitoring the graft survival by non-invasive imaging.
K. Ramkumar, Thillai V. Sekar, Elango Bhakkiyalakshmi, Kira Foygel +3 more
2013Current Medicinal Chemistry28 citations
Semantic Scholar
Genetically Encoded Molecular Biosensors To Image Histone Methylation in Living Animals
Thillai V. Sekar, Kira Foygel, J. Gelovani, R. Paulmurugan
2014Analytical Chemistry24 citations Open access
Semantic Scholar
Therapeutic Evaluation of microRNAs by Molecular Imaging
Thillai V. Sekar, R. Mohanram, Kira Foygel, R. Paulmurugan
2013Theranostics24 citations Open access
Semantic Scholar
A transgenic mouse model expressing an ERα folding biosensor reveals the effects of Bisphenol A on estrogen receptor signaling
Thillai V. Sekar, Kira Foygel, T. Massoud, S. Gambhir +1 more
2016Scientific Reports20 citations Open access
Semantic Scholar
Monitoring the Antioxidant Mediated Chemosensitization and ARE-Signaling in Triple Negative Breast Cancer Therapy
Kira Foygel, Thillai V. Sekar, R. Paulmurugan
2015PLoS ONE20 citations Open access
Semantic Scholar
Engineering Intracellularly Retained Gaussia Luciferase Reporters for Improved Biosensing and Molecular Imaging Applications
Shuchi Gaur, A. Bhargava-Shah, Sharon S. Hori, Rayhaneh Afjei +4 more
2017ACS Chemical Biology18 citations Open access
Semantic Scholar
Proteomic identification of pterostilbene-mediated anticancer activities in HepG2 cells.
N. Suganya, Elango Bhakkiyalakshmi, T. S. Subin, K. Krishnamurthi +5 more
2014Chemical Research in Toxicology16 citations
Semantic Scholar
Imaging cellular receptors in breast cancers: an overview.
Thillai V. Sekar, A. Dhanabalan, R. Paulmurugan
2011Current Pharmaceutical Biotechnology16 citations
Semantic Scholar
A protein folding molecular imaging biosensor monitors the effects of drugs that restore mutant p53 structure and its downstream function in glioblastoma cells
R. Paulmurugan, Rayhaneh Afjei, Thillai V. Sekar, Husam Babikir +1 more
2018OncoTarget14 citations Open access
Semantic Scholar
Dual-therapeutic reporter genes fusion for enhanced cancer gene therapy and imaging
Thillai V. Sekar, Kira Foygel, Jürgen K. Willmann, R. Paulmurugan
2012Gene Therapy14 citations
Semantic Scholar
Degron Protease Blockade Sensor to Image Epigenetic Histone Protein Methylation in Cells and Living Animals
Thillai V. Sekar, Kira Foygel, Rammohan Devulapally, R. Paulmurugan
2014ACS Chemical Biology10 citations Open access
Semantic Scholar
Biodegradable polymer nanocarriers for therapeutic antisense microRNA delivery in living animals
R. Paulmurugan, Narayana M. Sekar, Thillai V. Sekar
2012BiOS8 citations
Semantic Scholar
A beeline through Sir Peter James Kerley's life.
Thillai V. Sekar, K. Swan, Robert A Vietrogoski
2011AJR. American journal of roentgenology8 citations Open access
Semantic Scholar
Theranostic Imaging of Cancer Gene Therapy.
Thillai V. Sekar, R. Paulmurugan
2016Methods in molecular biology7 citations
Semantic Scholar
Simultaneous selection of nanobodies for accessible epitopes on immune cells in the tumor microenvironment
Thillai V. Sekar, E. Elghonaimy, Katy L. Swancutt, S. Diegeler +7 more
2021bioRxiv5 citations Open access
Semantic Scholar
A molecular imaging biosensor detects in vivo protein folding and misfolding
Anjali V. Sheahan, Thillai V. Sekar, Kai Chen, R. Paulmurugan +1 more
2016Journal of molecular medicine5 citations
Semantic Scholar
Biotin uptake by mouse and human pancreatic beta cells/islets: a regulated, lipopolysaccharide-sensitive carrier-mediated process.
Abhisek Ghosal, Thillai V. Sekar, H. Said
2014American Journal of Physiology - Gastrointestinal and Liver Physiology5 citations Open access
Semantic Scholar
Bioluminescence Imaging of Cancer Therapy
Thillai V. Sekar, R. Paulmurugan
20145 citations
Semantic Scholar
Restoration of the Lost Human Beta Defensin-1 Protein in Cancer as a Strategy to Improve the Efficacy of Chemotherapy
Raghu S Pandurangi, Thillai V. Sekar, R. Paulmurugan
2024Journal of Medicinal Chemistry4 citations Open access
Semantic Scholar
Molecular Imaging Biosensor Monitors p53 Sumoylation in Cells and Living Mice.
Thillai V. Sekar, Kira Foygel, Rammohan Devulapally, Vineet Kumar +3 more
2016Analytical Chemistry3 citations
Semantic Scholar
Restoration of the Lost Human Beta Defensin (hBD-1) in Cancer as a Strategy to Improve the Efficacy of Chemotherapy
Raghu S Pandurangi, Thillai V. Sekar, R. Paulmurugan
2023bioRxiv2 citations Open access
Semantic Scholar
Abstract 906: Molecular imaging of RRx-001-induced oxidative stress in Nrf2-luciferase expressing SCC VII tumors in mice
S. Ning, Thillai V. Sekar, R. Paulmurugan, J. Scicinski +3 more
20142 citations
Semantic Scholar
3H-Penciclovir (3H-PCV) Uptake Assay
Thillai V. Sekar, R. Paulmurugan
2013Bio-protocol2 citations Open access
Semantic Scholar
Imaging Histone Methylations in Living Animals.
Thillai V. Sekar, R. Paulmurugan
2016Methods in molecular biology1 citations
Semantic Scholar
Abstract 434: Target agnostic phage display for nanobodies that alter immune cell function.
P. Q. Leung, Todd A. Aguilera, E. Elghonaimy, Thillai V. Sekar +2 more
2026Cancer Research0 citations
Semantic Scholar
EXTH-61. TARGETED NANOPARTICLE DELIVERY OF THERAPEUTIC ANTIMIR-21 AND ANTIMIR-10B PRESENSITIZES GLIOBLASTOMA TO LOWER EFFECTIVE DOSES OF TEMOZOLOMIDE IN CELLS AND XENOGRAFTS
M. Malhotra, Thillai V. Sekar, Rammohan Devulapally, Rayhaneh Afjei +2 more
20170 citations Open access
Semantic Scholar
DDIS-16. A MOLECULAR IMAGING BIOSENSOR MONITORS THE EFFECTS OF ANTI-MISFOLDING DRUGS THAT RESTORE MUTANT p53 FUNCTION AND ENHANCE COMBINATION CHEMOTHERAPY FOR GLIOBLASTOMA
R. Paulmurugan, Rayhaneh Afjei, Husam Babikir, Thillai V. Sekar +1 more
20170 citations Open access
Semantic Scholar
Mechanism and regulation of biotin uptake by mouse and human pancreatic beta cells/islets: physiological and molecular aspects (909.2)
Abhisek Ghosal, Thillai V. Sekar, H. Said
20140 citations
Semantic Scholar
Abstract 5120: Monitoring antioxidant induced chemosensitization in triple negative breast cancer cells by Nrf2-luciferase fusion protein
Kira Foygel, Thillai V. Sekar, R. Paulmurugan
20140 citations
Semantic Scholar
S1822 Mechanisms and Regulation of Vitamin B1 (Thiamin) Uptake By Mouse and Human Pancreatic Cells
Lisa Mee, S. Nabokina, K. Maedler, Thillai V. Sekar +2 more
20090 citations
Semantic Scholar

Frequent co-authors

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R. Paulmurugan×36
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R. Paulmurugan — researcher profile on SciRah
Kira Foygel×15
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T. Massoud×10
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T. Massoud — researcher profile on SciRah
Rammohan Devulapally×9
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×5

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Rayhaneh Afjei — researcher profile on SciRah

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K. Ramkumar — researcher profile on SciRah

Elango Bhakkiyalakshmi×3

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Elango Bhakkiyalakshmi — researcher profile on SciRah

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P. Rajaguru — researcher profile on SciRah

Husam Babikir×3

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Husam Babikir — researcher profile on SciRah

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H. Said — researcher profile on SciRah

Narayana M. Sekar×2

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Narayana M. Sekar — researcher profile on SciRah

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J. Willmann — researcher profile on SciRah