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Xiao-Yun Fu · SciRah

Researcher profile · Semantic Scholar

Xiao-Yun Fu

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Xiao-Yun Fu — researcher profile on SciRah

h-index: 37
Works: 91
Citations: 5,090

Most-cited papers

Hypochlorous Acid Oxygenates the Cysteine Switch Domain of Pro-matrilysin (MMP-7)
Xiao-Yun Fu, S. Kassim, W. Parks, J. Heinecke
2001Journal of Biological Chemistry494 citations Open access
Semantic Scholar
The myeloperoxidase product hypochlorous acid oxidizes HDL in the human artery wall and impairs ABCA1-dependent cholesterol transport.
Constanze Bergt, S. Pennathur, Xiao-Yun Fu, Jaeman Byun +9 more
2004Proceedings of the National Academy of Sciences of the United States of America468 citations Open access
Semantic Scholar
Bcl-xL deamidation is a critical switch in the regulation of the response to DNA damage.
B. Deverman, Brian L. Cook, Scott R. Manson, Robert A. Niederhoff +8 more
2002Cell245 citations Open access
Semantic Scholar
Tyrosine 192 in Apolipoprotein A-I Is the Major Site of Nitration and Chlorination by Myeloperoxidase, but Only Chlorination Markedly Impairs ABCA1-dependent Cholesterol Transport*
Bao-Hai Shao, Constanze Bergt, Xiao-Yun Fu, P. Green +4 more
2005Journal of Biological Chemistry235 citations Open access
Semantic Scholar
N-acetylcysteine reduces the size and activity of von Willebrand factor in human plasma and mice.
Jun-Mei Chen, A. Reheman, F. Gushiken, L. Nolasco +4 more
2011Journal of Clinical Investigation234 citations Open access
Semantic Scholar
Myeloperoxidase Impairs ABCA1-dependent Cholesterol Efflux through Methionine Oxidation and Site-specific Tyrosine Chlorination of Apolipoprotein A-I*
Bao-Hai Shao, Michael N. Oda, Constanze Bergt, Xiao-Yun Fu +4 more
2006Journal of Biological Chemistry193 citations Open access
Semantic Scholar
Hypochlorous Acid Generated by Myeloperoxidase Modifies Adjacent Tryptophan and Glycine Residues in the Catalytic Domain of Matrix Metalloproteinase-7 (Matrilysin)
Xiao-Yun Fu, S. Kassim, W. Parks, J. Heinecke
2003Journal of Biological Chemistry162 citations Open access
Semantic Scholar
Methionine oxidation contributes to bacterial killing by the myeloperoxidase system of neutrophils
H. Rosen, S. Klebanoff, Yi Wang, N. Brot +2 more
2009Proceedings of the National Academy of Sciences of the United States of America160 citations Open access
Semantic Scholar
Oxidative modification of von Willebrand factor by neutrophil oxidants inhibits its cleavage by ADAMTS13.
Jun-Mei Chen, Xiao-Yun Fu, Yi Wang, Minhua Ling +4 more
2010Blood142 citations Open access
Semantic Scholar
Donor sex, age and ethnicity impact stored red blood cell antioxidant metabolism through mechanisms in part explained by glucose 6-phosphate dehydrogenase levels and activity
A. D'Alessandro, Xiao-Yun Fu, T. Kanias, J. Reisz +9 more
2020Haematologica137 citations Open access
Semantic Scholar
Myeloperoxidase Inactivates TIMP-1 by Oxidizing Its N-terminal Cysteine Residue
Yi Wang, H. Rosen, D. K. Madtes, Bao-Hai Shao +3 more
2007Journal of Biological Chemistry129 citations Open access
Semantic Scholar
Fibrin clot structure and mechanics associated with specific oxidation of methionine residues in fibrinogen.
Katie M. Weigandt, N. White, D. Chung, Eric C Ellingson +3 more
2012Biophysical Journal124 citations Open access
Semantic Scholar
Lysine Residues Direct the Chlorination of Tyrosines in YXXK Motifs of Apolipoprotein A-I When Hypochlorous Acid Oxidizes High Density Lipoprotein*
Constanze Bergt, Xiao-Yun Fu, N. Huq, J. Kao +1 more
2004Journal of Biological Chemistry121 citations Open access
Semantic Scholar
Spectral index for assessment of differential protein expression in shotgun proteomics.
Xiao-Yun Fu, S. Gharib, P. Green, M. Aitken +4 more
2008Journal of Proteome Research114 citations
Semantic Scholar
Acrolein Impairs ATP Binding Cassette Transporter A1-dependent Cholesterol Export from Cells through Site-specific Modification of Apolipoprotein A-I*
Bao-Hai Shao, Xiao-Yun Fu, Thomas O. McDonald, P. Green +4 more
2005Journal of Biological Chemistry114 citations Open access
Semantic Scholar
Generation of intramolecular and intermolecular sulfenamides, sulfinamides, and sulfonamides by hypochlorous acid: a potential pathway for oxidative cross-linking of low-density lipoprotein by myeloperoxidase.
Xiao-Yun Fu, Dianne M. Mueller, J. Heinecke
2002Biochemistry109 citations
Semantic Scholar
Unique Proteomic Signatures Distinguish Macrophages and Dendritic Cells
L. Becker, Ning-Chun Liu, Michelle Averill, W. Yuan +6 more
2012PLoS ONE106 citations Open access
Semantic Scholar
Activation and silencing of matrix metalloproteinases.
Xiao-Yun Fu, W. Parks, J. Heinecke
2008Seminars in Cell and Developmental Biology96 citations
Semantic Scholar
Heterogeneity of blood processing and storage additives in different centers impacts stored Red Blood Cell metabolism as much as storage time: lessons from REDS III – Omics
A. D'Alessandro, Rachel Culp-Hill, J. Reisz, Mikayla Anderson +13 more
2018Transfusion92 citations Open access
Semantic Scholar
Oxidative Cross-linking of Tryptophan to Glycine Restrains Matrix Metalloproteinase Activity
Xiao-Yun Fu, J. Kao, Constanze Bergt, S. Kassim +5 more
2004Journal of Biological Chemistry91 citations Open access
Semantic Scholar
Differences in Steap3 expression are a mechanism of genetic variation of RBC storage and oxidative damage in mice.
H. Howie, Ariel M. Hay, Karen S. deWolski, H. Waterman +9 more
2019Blood Advances81 citations Open access
Semantic Scholar
High-density lipoprotein modulates thrombosis by preventing von Willebrand factor self-association and subsequent platelet adhesion.
D. Chung, Jun-Mei Chen, Minhua Ling, Xiao-Yun Fu +8 more
2016Blood81 citations Open access
Semantic Scholar
Shear stress-induced unfolding of VWF accelerates oxidation of key methionine residues in the A1A2A3 region.
Xiao-Yun Fu, Jun-Mei Chen, Ryan Gallagher, Ying Zheng +2 more
2010Blood78 citations Open access
Semantic Scholar
Decellularized Human Kidney Cortex Hydrogels Enhance Kidney Microvascular Endothelial Cell Maturation and Quiescence
Ryan J. Nagao, Jin Xu, P. Luo, Jun Xue +6 more
2016Tissue Engineering. Part A77 citations Open access
Semantic Scholar
NADPH Oxidase Restrains the Matrix Metalloproteinase Activity of Macrophages*
S. Kassim, Xiao-Yun Fu, W. C. Liles, S. Shapiro +2 more
2005Journal of Biological Chemistry73 citations Open access
Semantic Scholar
Hypochlorous Acid Generated by Neutrophils Inactivates ADAMTS13
Yi Wang, Jun-Mei Chen, Minhua Ling, José A. López +2 more
2014Journal of Biological Chemistry67 citations Open access
Semantic Scholar
Addition of ascorbic acid solution to stored murine red blood cells increases posttransfusion recovery and decreases microparticles and alloimmunization
S. Stowell, Nicole H. Smith, James C. Zimring, Xiao-Yun Fu +4 more
2013Transfusion64 citations
Semantic Scholar
Post-translational oxidative modification of fibrinogen is associated with coagulopathy after traumatic injury
N. White, Yi Wang, Xiao-Yun Fu, Jessica C. Cardenas +10 more
2016Free Radical Biology & Medicine58 citations Open access
Semantic Scholar
The biological activity of FasL in human and mouse lungs is determined by the structure of its stalk region.
R. Herrero, O. Kajikawa, G. Matute-Bello, Yi Wang +10 more
2011Journal of Clinical Investigation58 citations Open access
Semantic Scholar
Bioactive lipids accumulate in stored red blood cells despite leukoreduction: a targeted metabolomics study
Xiao-Yun Fu, Jacob R. Felcyn, K. Odem-Davis, J. Zimring
2016Transfusion56 citations
Semantic Scholar
Cysteine Disulfides (Cys-ss-X) as Sensitive Plasma Biomarkers of Oxidative Stress
Xiao-Yun Fu, Shelby A. Cate, Melissa G. Dominguez, Warren Osborn +4 more
2019Scientific Reports55 citations Open access
Semantic Scholar
Acrolein Modifies Apolipoprotein A‐I in the Human Artery Wall
Bao-Hai Shao, K. O'Brien, Thomas O. McDonald, Xiao-Yun Fu +3 more
2005Annals of the New York Academy of Sciences52 citations
Semantic Scholar
Mapping the lung proteome in cystic fibrosis.
S. Gharib, T. Vaisar, M. Aitken, David R. Park +2 more
2009Journal of Proteome Research50 citations
Semantic Scholar
Nicotine exposure increases markers of oxidant stress in stored red blood cells from healthy donor volunteers
D. Stefanoni, Xiao-Yun Fu, J. Reisz, T. Kanias +9 more
2020Transfusion46 citations Open access
Semantic Scholar
Fatty acid desaturase activity in mature red blood cells and implications for blood storage quality
T. Thomas, F. Cendali, Xiao-Yun Fu, F. Gamboni +14 more
2021Transfusion42 citations Open access
Semantic Scholar
Metabolites in stored platelets associated with platelet recoveries and survivals
J. Zimring, S. Slichter, K. Odem-Davis, Jacob R. Felcyn +8 more
2016Transfusion41 citations
Semantic Scholar
Methionine Sulfoxide and Proteolytic Cleavage Contribute to the Inactivation of Cathepsin G by Hypochlorous Acid
Bao-Hai Shao, A. Belaaouaj, C. Verlinde, Xiao-Yun Fu +1 more
2005Journal of Biological Chemistry39 citations Open access
Semantic Scholar
Impact of taurine on red blood cell metabolism and implications for blood storage
L. Bertolone, M. Roy, Ariel M. Hay, Evan J. Morrison +10 more
2020Transfusion35 citations Open access
Semantic Scholar
Involvement of Annexin A1 in Multidrug Resistance of K562/ADR Cells Identified by the Proteomic Study
Fengjia Zhu, Yi Wang, S. Zeng, Xiao-Yun Fu +2 more
2009Omics34 citations
Semantic Scholar
Hematologic and systemic metabolic alterations due to Mediterranean class II G6PD deficiency in mice
A. D'Alessandro, H. Howie, Ariel M. Hay, Karolina H. Dziewulska +10 more
2021JCI Insight31 citations Open access
Semantic Scholar
Reexamination of the chromium‐51–labeled posttransfusion red blood cell recovery method
R. Francis, S. Mahajan, F. Rapido, Francesca La Carpia +18 more
2019Transfusion30 citations
Semantic Scholar
Simultaneous Exposure of Sites in von Willebrand Factor for Glycoprotein Ib Binding and ADAMTS13 Cleavage: Studies With Ristocetin
Jun-Mei Chen, Minhua Ling, Xiao-Yun Fu, José A. López +1 more
2012Arteriosclerosis, Thrombosis and Vascular Biology30 citations Open access
Semantic Scholar
Specific sequence motifs direct the oxygenation and chlorination of tryptophan by myeloperoxidase.
Xiao-Yun Fu, Yi Wang, Jeffery Kao, Angela D. Irwin +4 more
2006Biochemistry30 citations Open access
Semantic Scholar
Stored RBC metabolism as a function of caffeine levels
A. D'Alessandro, Xiao-Yun Fu, J. Reisz, T. Kanias +5 more
2020Transfusion28 citations Open access
Semantic Scholar
Ethyl glucuronide, a marker of alcohol consumption, correlates with metabolic markers of oxidant stress but not with hemolysis in stored red blood cells from healthy blood donors
A. D'Alessandro, Xiao-Yun Fu, J. Reisz, M. Stone +3 more
2020Transfusion28 citations Open access
Semantic Scholar
Piloting and implementation of quality assessment and quality control procedures in RBC‐Omics: a large multi‐center study of red blood cell hemolysis during storage
M. Stone, S. Keating, T. Kanias, M. Lanteri +18 more
2018Transfusion25 citations
Semantic Scholar
Deficiency of Superoxide Dismutase Impairs Protein C Activation and Enhances Susceptibility to Experimental Thrombosis
S. Dayal, Sean X Gu, Ryan D. Hutchins, Katina M. Wilson +3 more
2015Arteriosclerosis, Thrombosis and Vascular Biology24 citations Open access
Semantic Scholar
The clinical impact of glucose-6-phosphate dehydrogenase deficiency in patients with sickle cell disease
Matthew S. Karafin, Xiao-Yun Fu, A. D'Alessandro, T. Thomas +4 more
2018Current opinion in hematology22 citations
Semantic Scholar
Arterial Platelet Adhesion in Atherosclerosis‐Prone Arteries of Obese, Insulin‐Resistant Nonhuman Primates
Eran Brown, Koya Ozawa, F. Moccetti, A. Vinson +11 more
2021Journal of the American Heart Association : Cardiovascular and Cerebrovascular Disease20 citations Open access
Semantic Scholar
Hypochlorous Acid Converts the γ-Glutamyl Group of Glutathione Disulfide to 5-Hydroxybutyrolactam, a Potential Marker for Neutrophil Activation*
W. Yuan, Yi Wang, J. Heinecke, Xiao-Yun Fu
2009Journal of Biological Chemistry20 citations Open access
Semantic Scholar

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