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O. Igoucheva · SciRah

Researcher profile · Semantic Scholar

O. Igoucheva

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O. Igoucheva — researcher profile on SciRah

h-index: 25
Works: 53
Citations: 1,640

Most-cited papers

Targeted gene correction by small single-stranded oligonucleotides in mammalian cells
O. Igoucheva, V. Alexeev, K. Yoon
2001Gene Therapy157 citations Open access
Semantic Scholar
Localized in vivo genotypic and phenotypic correction of the albino mutation in skin by RNA-DNA oligonucleotide
V. Alexeev, O. Igoucheva, A. Domashenko, G. Cotsarelis +1 more
2000Nature Biotechnology129 citations
Semantic Scholar
MicroRNA-dependent regulation of cKit in cutaneous melanoma.
O. Igoucheva, V. Alexeev
2009Biochemical and Biophysical Research Communications - BBRC105 citations
Semantic Scholar
Highly branched poly(β-amino ester)s for skin gene therapy.
De-Zhong Zhou, Yong-Sheng Gao, A. Aied, L. Cutlar +6 more
2016Journal of Controlled Release101 citations
Semantic Scholar
Transcription affects formation and processing of intermediates in oligonucleotide-mediated gene alteration.
O. Igoucheva, V. Alexeev, Melissa Pryce, K. Yoon
2003Nucleic Acids Research69 citations Open access
Semantic Scholar
Oligonucleotide-directed mutagenesis and targeted gene correction: a mechanistic point of view.
O. Igoucheva, V. Alexeev, K. Yoon
2004Current molecular medicine66 citations
Semantic Scholar
Oligonucleotide-directed single-base DNA alterations in mouse embryonic stem cells
Eric A. Pierce, Qin Liu, O. Igoucheva, R. Omarrudin +3 more
2003Gene Therapy65 citations Open access
Semantic Scholar
Misbalanced CXCL12 and CCL5 Chemotactic Signals in Vitiligo Onset and Progression.
A. Rezk, D. M. Kemp, M. El-Domyati, W. H. El-Din +4 more
2017Journal of Investigative Dermatology63 citations Open access
Semantic Scholar
Human adipose-derived stem cell transplantation as a potential therapy for collagen VI-related congenital muscular dystrophy
V. Alexeev, M. Arita, A. Donahue, P. Bonaldo +2 more
2014Stem cell research & therapeutics49 citations Open access
Semantic Scholar
Fibulin-4 E57K Knock-in Mice Recapitulate Cutaneous, Vascular and Skeletal Defects of Recessive Cutis Laxa 1B with both Elastic Fiber and Collagen Fibril Abnormalities*
O. Igoucheva, V. Alexeev, C. Halabi, Sheila Adams +7 more
2015Journal of Biological Chemistry46 citations Open access
Semantic Scholar
Characterization of the CCL21-mediated melanoma-specific immune responses and in situ melanoma eradication
Laura Novak, O. Igoucheva, Stephanie Cho, V. Alexeev
2007Molecular Cancer Therapeutics45 citations
Semantic Scholar
Simultaneous targeted alteration of the tyrosinase and c-kit genes by single-stranded oligonucleotides
V. Alexeev, O. Igoucheva, K. Yoon
2002Gene Therapy45 citations Open access
Semantic Scholar
A sequence-specific gene correction by an RNA-DNA oligonucleotide in mammalian cells characterized by transfection and nuclear extract using a lacZ shuttle system
O. Igoucheva, A. Peritz, D. Levy, K. Yoon
1999Gene Therapy45 citations Open access
Semantic Scholar
Pro-inflammatory chemokines and cytokines dominate the blister fluid molecular signature in epidermolysis bullosa patients and affect leukocyte and stem cell migration
V. Alexeev, J. Salas-Alanis, F. Palisson, L. Mukhtarzada +4 more
2017Journal of Investigative Dermatology44 citations Open access
Semantic Scholar
RNAi‐mediated silencing of insulin receptor substrate 1 (IRS‐1) enhances tamoxifen‐induced cell death in MCF‐7 breast cancer cells
G. Cesarone, C. Garofalo, M. Abrams, O. Igoucheva +4 more
2006Journal of Cellular Biochemistry44 citations
Semantic Scholar
Differential cellular responses to exogenous DNA in mammalian cells and its effect on oligonucleotide-directed gene modification
O. Igoucheva, V. Alexeev, K. Yoon
2006Gene Therapy42 citations
Semantic Scholar
Intracellular escape strategies of Staphylococcus aureus in persistent cutaneous infections
L. Huitema, T. Phillips, V. Alexeev, M. Tomic-Canic +2 more
2020Experimental Dermatology41 citations Open access
Semantic Scholar
Ladarixin, a dual CXCR1/2 inhibitor, attenuates experimental melanomas harboring different molecular defects by affecting malignant cells and tumor microenvironment
D. M. Kemp, A. Pidich, M. Larijani, R. Jonas +7 more
2017OncoTarget41 citations Open access
Semantic Scholar
Analysis of chemotactic molecules in bone marrow-derived mesenchymal stem cells and the skin: Ccl27-Ccr10 axis as a basis for targeting to cutaneous tissues
V. Alexeev, A. Donahue, J. Uitto, O. Igoucheva
2013Cytotherapy36 citations Open access
Semantic Scholar
Immunological mechanisms underlying progression of chronic wounds in recessive dystrophic epidermolysis bullosa
L. Huitema, T. Phillips, V. Alexeev, O. Igoucheva
2021Experimental Dermatology35 citations Open access
Semantic Scholar
Gene expression signatures of mouse bone marrow-derived mesenchymal stem cells in the cutaneous environment and therapeutic implications for blistering skin disorder.
V. Alexeev, J. Uitto, O. Igoucheva
2011Cytotherapy34 citations
Semantic Scholar
Involvement of ERCC1/XPF and XPG in Oligodeoxynucleotide-directed Gene Modification
O. Igoucheva, V. Alexeev, O. Scharer, K. Yoon
2006Oligonucleotides33 citations
Semantic Scholar
Systemic CXCL10 is a predictive biomarker of vitiligo lesional skin infiltration, PUVA, NB-UVB and corticosteroid treatment response and outcome
M. El-Domyati, W. H. El-Din, A. Rezk, I. Chervoneva +5 more
2021Archives of Dermatological Research32 citations
Semantic Scholar
Protein therapeutics for junctional epidermolysis bullosa: incorporation of recombinant beta3 chain into laminin 332 in beta3-/- keratinocytes in vitro.
O. Igoucheva, A. Kelly, J. Uitto, V. Alexeev
2008Journal of Investigative Dermatology31 citations Open access
Semantic Scholar
Nuclear Extracts Promote Gene Correction and Strand Pairing of Oligonucleotides to the Homologous Plasmid
O. Igoucheva, V. Alexeev, K. Yoon
2002Antisense and Nucleic Acid Drug Development27 citations
Semantic Scholar
Oligonucleotide-Mediated Gene Targeting in Human Hepatocytes: Implications of Mismatch Repair
O. Igoucheva, V. Alexeev, H. Anni, E. Rubin
2008Oligonucleotides24 citations Open access
Semantic Scholar
Targeted Single-Base Correction by RNA–DNA Oligonucleotides
O. Igoucheva, K. Yoon
2000Human Gene Therapy23 citations
Semantic Scholar
Immunotargeting and eradication of orthotopic melanoma using a chemokine-enhanced DNA vaccine
O. Igoucheva, M. Grazzini, A. Pidich, D. M. Kemp +5 more
2013Gene Therapy21 citations
Semantic Scholar
Expectations and reality in gene repair
K. Yoon, O. Igoucheva, V. Alexeev
2002Nature Biotechnology21 citations
Semantic Scholar
Mechanism of Gene Repair Open for Discussion
O. Igoucheva, V. Alexeev, K. Yoon
2004Oligonucleotides20 citations
Semantic Scholar
Aberrant recruitment of leukocytes defines poor wound healing in patients with recessive dystrophic epidermolysis bullosa.
T. Phillips, L. Huitema, Rodrigo E. Cepeda, Diego de Los Cobos +8 more
2020Journal of dermatological science (Amsterdam)18 citations Open access
Semantic Scholar
A role for the Werner syndrome protein in epigenetic inactivation of the pluripotency factor Oct4
Johanna A. Smith, A. Ndoye, Kyla R. Geary, M. Lisanti +2 more
2010Aging Cell18 citations Open access
Semantic Scholar
Chemotaxis-driven disease-site targeting of therapeutic adult stem cells in dystrophic epidermolysis bullosa
V. Alexeev, A. Donahue, J. Uitto, O. Igoucheva
2016Stem cell research & therapeutics12 citations Open access
Semantic Scholar
T‐cell activation and bacterial infection in skin wounds of recessive dystrophic epidermolysis bullosa patients
V. Alexeev, L. Huitema, Taylor Phillips, Rodrigo E. Cepeda +8 more
2022Experimental Dermatology11 citations Open access
Semantic Scholar
Site-specific gene modification by oligodeoxynucleotides in mouse bone marrow-derived mesenchymal stem cells
K. Flagler, V. Alexeev, Eric A. Pierce, O. Igoucheva
2008Gene Therapy11 citations Open access
Semantic Scholar
Improvement of RNA-DNA oligonucleotide design by using mammalian nuclear extracts
O. Igoucheva, K. Yoon
20009 citations
Semantic Scholar
Congenital muscular dystrophy-associated inflammatory chemokines provide axes for effective recruitment of therapeutic adult stem cell into muscles
V. Alexeev, Jacquelyn Olavarria, P. Bonaldo, L. Merlini +1 more
2020Stem cell research & therapeutics6 citations Open access
Semantic Scholar
High concordance between clinical diagnosis of epidermolysis bullosa and immunofluorescence with a small, well‐matched antibody panel
I. Meester, O. Igoucheva, V. Alexeev, A. South +2 more
2018Australasian Journal of Dermatology4 citations
Semantic Scholar
Immunotherapeutic strategies for the treatment of malignant melanoma.
V. Alexeev, T. Mucci, O. Igoucheva
2008Giornale italiano di dermatologia e venereologia : organo ufficiale, Societa italiana di dermatologia e sifilografia4 citations
Semantic Scholar
Gene targeting by oligonucleotides in keratinocytes.
O. Igoucheva, K. Yoon
2005Methods in molecular biology4 citations
Semantic Scholar
Chemokine-enhanced DNA vaccination in cancer immunotherapy
O. Igoucheva, R. Jonas, V. Alexeev
2013Oncoimmunology3 citations Open access
Semantic Scholar
Gene correction frequency by chimeric RNA-DNA oligonucleotide using nuclear extracts.
O. Igoucheva, K. Yoon
2002Methods in Molecular Medicine3 citations
Semantic Scholar
Recombinant DNA Technology in Emerging Modalities for Melanoma Immunotherapy
V. Alexeev, A. Pidich, D. M. Kemp, O. Igoucheva
20132 citations Open access
Semantic Scholar
Cross-sectional analysis of wound-associated soluble factors in early, established, and chronic wounds of recessive dystrophic epidermolysis bullosa patients
V. Alexeev, L. Huitema, Taylor Phillips, Paras Patel +4 more
2025Archives of Dermatological Research1 citations Open access
Semantic Scholar
614 Deregulation of chemotactic signals in segmental and non-segmental vitiligo
M. El-Domyati, W. H. El-Din, A. Rezk, J. Uitto +3 more
20161 citations Open access
Semantic Scholar
Retroviral delivery of ECM genes.
V. Alexeev, O. Igoucheva
2009Methods in molecular biology1 citations
Semantic Scholar
Cancer Vaccine Targeting Mutated GNAQ-Expressing Uveal Melanoma
V. Alexeev, Mizue Terai, Sergei Koshkin, O. Igoucheva +1 more
2026Cancers0 citations Open access
Semantic Scholar
LB1007 Analysis of chemokines in blister fluids of epidermolysis bullosa patients: Implications for therapy
V. Alexeev, L. Mukhtarzada, J. Alanis, F. Palisson +3 more
20170 citations Open access
Semantic Scholar
613 Evaluation of CXCL10 chemokine in vitiligo
M. El-Domyati, W. H. El-Din, A. Rezk, J. Uitto +4 more
20160 citations Open access
Semantic Scholar
416 Proteomic analysis of chemokines and cytokines in blister fluids of epidermolysis bullosa patients: Implications for prognosis and therapy
V. Alexeev, A. Donahue, J. Salas-Alanis, F. Palisson +2 more
20160 citations Open access
Semantic Scholar

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