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L. Taams · SciRah

Researcher profile · Semantic Scholar

L. Taams

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L. Taams — researcher profile on SciRah

h-index: 52
Works: 197
Citations: 9,977

Most-cited papers

IL-17 in the immunopathogenesis of spondyloarthritis
L. Taams, K. Steel, U. Srenathan, L. Burns +1 more
2018Nature Reviews Rheumatology152 citations Open access
Semantic Scholar
IL-17+ CD8+ T cells: Differentiation, phenotype and role in inflammatory disease
U. Srenathan, K. Steel, L. Taams
2016Immunology Letters132 citations Open access
Semantic Scholar
Interleukin-17 in rheumatoid arthritis: Trials and tribulations
L. Taams
2020Journal of Experimental Medicine126 citations Open access
Semantic Scholar
The cholesterol biosynthesis pathway regulates IL-10 expression in human Th1 cells
E. Perucha, R. Melchiotti, Jack A. Bibby, Wing Wu +14 more
2019Nature Communications125 citations Open access
Semantic Scholar
Polyfunctional, Proinflammatory, Tissue‐Resident Memory Phenotype and Function of Synovial Interleukin‐17A+CD8+ T Cells in Psoriatic Arthritis
K. Steel, U. Srenathan, M. Ridley, Lucy E. Durham +6 more
2020Arthritis & Rheumatology121 citations Open access
Semantic Scholar
Upregulation of Glucose Uptake and Hexokinase Activity of Primary Human CD4+ T Cells in Response to Infection with HIV-1
Maia Kavanagh Williamson, N. Coombes, Florian Juszczak, Marios Athanasopoulos +7 more
2018Viruses89 citations Open access
Semantic Scholar
MicroRNA-155 contributes to enhanced resistance to apoptosis in monocytes from patients with rheumatoid arthritis
Megha Rajasekhar, A. Olsson, K. Steel, M. Georgouli +4 more
2017Journal of Autoimmunity87 citations Open access
Semantic Scholar
Human milk extracellular vesicles target nodes in interconnected signalling pathways that enhance oral epithelial barrier function and dampen immune responses
Marijke I. Zonneveld, M. V. van Herwijnen, Marcela M. Fernandez-Gutierrez, Alberta Giovanazzi +11 more
2020bioRxiv84 citations Open access
Semantic Scholar
Periodontitis‐associated pathogens P. gingivalis and A. actinomycetemcomitans activate human CD14+ monocytes leading to enhanced Th17/IL‐17 responses
Wan-Chien Cheng, Saskia D. van Asten, L. Burns, H. Evans +4 more
2016European Journal of Immunology83 citations Open access
Semantic Scholar
Inflammatory cytokines compromise programmed cell death‐1 (PD‐1)‐mediated T cell suppression in inflammatory arthritis through up‐regulation of soluble PD‐1
D. Bommarito, C. Hall, L. Taams, V. Corrigall
2017Clinical and Experimental Immunology76 citations Open access
Semantic Scholar
Brain injury in COVID-19 is associated with dysregulated innate and adaptive immune responses
E. Needham, A. Ren, R. Digby, E. Norton +36 more
2022Brain : a journal of neurology75 citations Open access
Semantic Scholar
Conserved human effector Treg cell transcriptomic and epigenetic signature in arthritic joint inflammation
G. Mijnheer, L. Lutter, M. Mokry, Marlot van der Wal +15 more
2021Nature Communications75 citations Open access
Semantic Scholar
Psoriatic and rheumatoid arthritis joints differ in the composition of CD8+ tissue-resident memory T cell subsets
G. A. Povoleri, Lucy E. Durham, Elizabeth H. Gray, S. Lalnunhlimi +8 more
2023Cell Reports54 citations Open access
Semantic Scholar
Mechanisms of checkpoint inhibition‐induced adverse events
P. Urwyler, I. Earnshaw, M. Bermúdez, E. Perucha +8 more
2020Clinical and Experimental Immunology49 citations Open access
Semantic Scholar
Sensitization of knee-innervating sensory neurons by tumor necrosis factor-α-activated fibroblast-like synoviocytes: an in vitro, coculture model of inflammatory pain
Sampurna Chakrabarti, Zoe Hore, Luke A. Pattison, S. Lalnunhlimi +6 more
2020Pain48 citations Open access
Semantic Scholar
Interleukin-10 and prostaglandin E2 have complementary but distinct suppressive effects on Toll-like receptor-mediated dendritic cell activation in ovarian carcinoma
E. Brenčičová, A. Jagger, H. Evans, M. Georgouli +8 more
2017PLoS ONE40 citations Open access
Semantic Scholar
Presence, function, and regulation of IL‐17F‐expressing human CD4+ T cells
L. Burns, A. Maroof, D. Marshall, Kathryn J. A. Steel +5 more
2019European Journal of Immunology39 citations Open access
Semantic Scholar
An interdisciplinary perspective on peripheral drivers of pain in rheumatoid arthritis
Z. Rutter-Locher, Bruce W. Kirkham, K. Bannister, D. L. Bennett +3 more
2024Nature Reviews Rheumatology38 citations Open access
Semantic Scholar
Efficacy and safety of ciclosporin versus methotrexate in the treatment of severe atopic dermatitis in children and young people (TREAT): a multicentre parallel group assessor-blinded clinical trial
C. Flohr, A. Rosala-Hallas, A. Jones, P. Beattie +25 more
2023British Journal of Dermatology34 citations Open access
Semantic Scholar
Para-infectious brain injury in COVID-19 persists at follow-up despite attenuated cytokine and autoantibody responses
B. Michael, C. Dunai, E. Needham, K. Tharmaratnam +42 more
2023Nature Communications32 citations Open access
Semantic Scholar
TNF Blockade Maintains an IL-10+ Phenotype in Human Effector CD4+ and CD8+ T Cells
C. Roberts, Lucy E. Durham, V. Fleskens, H. Evans +1 more
2017Frontiers in Immunology31 citations Open access
Semantic Scholar
Proteome-wide Mendelian randomization identifies causal links between blood proteins and severe COVID-19
A. Palmos, V. Millischer, D. Menon, T. Nicholson +6 more
2021medRxiv30 citations Open access
Semantic Scholar
Inflammation and immune resolution
L. Taams
2018Clinical and Experimental Immunology29 citations Open access
Semantic Scholar
A systematic review and meta-analysis of questionnaires to screen for pain sensitisation and neuropathic like pain in inflammatory arthritis.
Z. Rutter-Locher, N. Arumalla, S. Norton, L. Taams +2 more
2023Seminars in Arthritis & Rheumatism28 citations
Semantic Scholar
Circulating inflammatory proteins associate with response to immune checkpoint inhibition therapy in patients with advanced melanoma
N. Rossi, Karla A. Lee, M. V. Bermudez, A. Visconti +22 more
2022EBioMedicine28 citations Open access
Semantic Scholar
Comparative analysis of immune cell subsets in peripheral blood from patients with periodontal disease and healthy controls
Wan-Chien Cheng, F. Saleh, B. Karim, F. Hughes +1 more
2018Clinical and Experimental Immunology27 citations Open access
Semantic Scholar
IKZF3/Aiolos Is Associated with but Not Sufficient for the Expression of IL-10 by CD4+ T Cells
M. Ridley, V. Fleskens, C. Roberts, S. Lalnunhlimi +7 more
2020Journal of Immunology19 citations Open access
Semantic Scholar
Drivers of Inflammation in Psoriatic Arthritis: the Old and the New
Charlotte O’Brien-Gore, Elizabeth H. Gray, Lucy E. Durham, L. Taams +1 more
2021Current Rheumatology Reports18 citations
Semantic Scholar
Neuroimmune interactions: how the nervous and immune systems influence each other
L. Taams
2019Clinical and Experimental Immunology18 citations Open access
Semantic Scholar
A randomised controlled trial of the effect of intra-articular lidocaine on pain scores in inflammatory arthritis
Z. Rutter-Locher, S. Norton, F. Denk, Stephen B. McMahon +3 more
2023medRxiv16 citations Open access
Semantic Scholar
A randomized controlled trial protocol assessing the effectiveness, safety and cost‐effectiveness of methotrexate vs. ciclosporin in the treatment of severe atopic eczema in children: the TREatment of severe Atopic eczema Trial (TREAT)
A. Irvine, A. Jones, P. Beattie, S. Baron +12 more
2018British Journal of Dermatology16 citations Open access
Semantic Scholar
Linking Skin and Joint Inflammation in Psoriatic Arthritis through Shared CD8+ T Cell Clones
Lucy E. Durham, F. Humby, Nora Ng, R. Laddach +11 more
2025Arthritis & Rheumatology14 citations Open access
Semantic Scholar
miR-155-overexpressing monocytes resemble HLAhighISG15+ synovial tissue macrophages from patients with rheumatoid arthritis and induce polyfunctional CD4+ T-cell activation
A. Olsson, G. A. Povoleri, Domenico Somma, M. Ridley +7 more
2021Clinical and Experimental Immunology14 citations Open access
Semantic Scholar
Substantive Similarities Between Synovial Fluid and Synovial Tissue T cells in Inflammatory Arthritis Via Single‐Cell RNA and T Cell Receptor Sequencing
Lucy E. Durham, F. Humby, Nora Ng, Sarah E. Ryan +6 more
2024Arthritis & Rheumatology13 citations Open access
Semantic Scholar
Para-infectious brain injury in COVID-19 persists at follow-up despite attenuated cytokine and autoantibody responses
B. Michael, C. Dunai, Edward J. Needham, K. Tharmaratnam +33 more
2023medRxiv11 citations Open access
Semantic Scholar
Lipidome profiling of neutrophil-derived extracellular vesicles unveils their contribution to the ensemble of synovial fluid-derived extracellular vesicles during joint inflammation.
L. Varela, Sanne Mol, Esther W. M. Taanman-Kueter, Sarah E. Ryan +5 more
2024Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids8 citations Open access
Semantic Scholar
Modelling inflammation-induced peripheral sensitization in a dish—more complex than expected?
Yue-Ning Li, Amy Lock, Laura Fedele, Irene Zebochin +10 more
2024bioRxiv8 citations Open access
Semantic Scholar
Human in vitro-induced IL-17A+ CD8+ T-cells exert pro-inflammatory effects on synovial fibroblasts
Elizabeth H. Gray, U. Srenathan, Lucy E. Durham, S. Lalnunhlimi +4 more
2023Clinical and Experimental Immunology8 citations Open access
Semantic Scholar
Rheumatoid arthritis synovial fluid induces JAK-dependent intracellular activation of human sensory neurons
Yue-Ning Li, Elizabeth H. Gray, R. Ross, Irene Zebochin +10 more
2025JCI Insight7 citations Open access
Semantic Scholar
O016 Synovial IL-17+ CD8+ T cells are a pro-inflammatory tissue resident population enriched in spondyloarthritis
K. Steel, S.-Y. Wu, U. Srenathan, E. Chan +2 more
20187 citations Open access
Semantic Scholar
Optimising psoriatic arthritis therapy with immunological methods to increase standard evaluation: the protocol of an open-label multicentre, parallel-group, two-arm randomised controlled study evaluation precision medicine approach in the treatment of psoriatic arthritis
Alexander Ooms, H. Al-Mossawi, Louise Bennett, M. Bogale +12 more
2023BMJ Open6 citations Open access
Semantic Scholar
Pulmonary SARS-CoV-2 infection leads to para-infectious immune activation in the brain
C. Dunai, Claire Hetherington, S. Boardman, J. J. Clark +24 more
2024Frontiers in Immunology5 citations Open access
Semantic Scholar
BiTE therapy for rheumatoid arthritis
F. Humby, Bruce W. Kirkham, L. Taams
2024Nature Medicine5 citations
Semantic Scholar
Type 17-specific immune pathways are active in early spondyloarthritis
C. Hughes, Sarah E. Ryan, K. Steel, M. D. van den Beukel +6 more
2023RMD Open5 citations Open access
Semantic Scholar
Immune checkpoint inhibition: from molecules to clinical application
L. Taams, T. D. Gruijl
2020Clinical and Experimental Immunology5 citations Open access
Semantic Scholar
Precision medicine in psoriatic arthritis: how should we select targeted therapies?
H. Al-Mossawi, L. Taams, C. Goodyear, B. Kirkham +3 more
2019The Lancet Rheumatology5 citations Open access
Semantic Scholar
A role for fibroblast and mural cell subsets in a nerve ligation model of neuropathic pain?
Sara Villa-Hernandez, Julia Vlachaki Walker, Zoe Hore, Laura Fedele +7 more
2025bioRxiv4 citations Open access
Semantic Scholar
Assessment of Pain Types in Recently Diagnosed Patients With Inflammatory Arthritis
Z. Rutter-Locher, S. Norton, Joseph Taylor, B. Menon +5 more
2025medRxiv4 citations Open access
Semantic Scholar
Comparative analysis of centrally mediated and inflammatory pain experiences amongst patients diagnosed with rheumatoid arthritis: A multimethods study
Z. Rutter-Locher, T. Esterine, Ruth Williams, L. Taams +3 more
2024Health Expectations4 citations Open access
Semantic Scholar
Research priorities for neuroimmunology: identifying the key research questions to be addressed by 2030
G. MacKenzie, S. Subramaniam, Lindsey J Caldwell, Denise C. Fitzgerald +13 more
2021Wellcome Open Research4 citations Open access
Semantic Scholar

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Lucy E. Durham×7
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Bruce W. Kirkham

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C. Roberts — researcher profile on SciRah

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G. A. Povoleri×4

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