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P. Kirke · SciRah

Researcher profile · Semantic Scholar

P. Kirke

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P. Kirke — researcher profile on SciRah

h-index: 39
Works: 89
Citations: 7,199

Most-cited papers

Folate levels and neural tube defects. Implications for prevention.
L. Daly, P. Kirke, A. Molloy, D. G. Weir +1 more
1995Journal of the American Medical Association (JAMA)810 citations
Semantic Scholar
Homocysteine metabolism in pregnancies complicated by neural-tube defects.
J. Mills, J. Mcpartlin, P. Kirke, Young Jack Lee +3 more
1995The Lancet693 citations
Semantic Scholar
Maternal plasma folate and vitamin B12 are independent risk factors for neural tube defects.
P. Kirke, A. Molloy, L. Daly, Helen Burke +2 more
1993The Quarterly journal of medicine564 citations
Semantic Scholar
Thermolabile variant of 5,10-methylenetetrahydrofolate reductase associated with low red-cell folates: implications for folate intake recommendations.
A. Molloy, S. Daly, J. Mills, P. Kirke +5 more
1997The Lancet367 citations
Semantic Scholar
A genetic defect in 5,10 methylenetetrahydrofolate reductase in neural tube defects.
A. Whitehead, Paula M. Gallagher, J. Mills, P. Kirke +5 more
1995QJM : monthly journal of the Association of Physicians354 citations
Semantic Scholar
Effects of Folate and Vitamin B12 Deficiencies During Pregnancy on Fetal, Infant, and Child Development
A. Molloy, P. Kirke, L. Brody, J. Scott +1 more
2008Food and Nutrition Bulletin325 citations
Semantic Scholar
Minimum effective dose of folic acid for food fortification to prevent neural-tube defects.
S. Daly, J. Mills, A. Molloy, M. Conley +4 more
1997The Lancet317 citations
Semantic Scholar
Maternal Vitamin B12 Status and Risk of Neural Tube Defects in a Population With High Neural Tube Defect Prevalence and No Folic Acid Fortification
A. Molloy, P. Kirke, J. Troendle, Helen Burke +4 more
2009Pediatrics313 citations Open access
Semantic Scholar
A polymorphism, R653Q, in the trifunctional enzyme methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase/formyltetrahydrofolate synthetase is a maternal genetic risk factor for neural tube defects: report of the Birth Defects Research Group.
L. Brody, M. Conley, Christopher Cox, P. Kirke +7 more
2002American Journal of Human Genetics250 citations Open access
Semantic Scholar
The "thermolabile" variant of methylenetetrahydrofolate reductase and neural tube defects: An evaluation of genetic risk and the relative importance of the genotypes of the embryo and the mother.
D. Shields, P. Kirke, J. Mills, D. Ramsbottom +5 more
1999American Journal of Human Genetics248 citations Open access
Semantic Scholar
MTRR and MTHFR polymorphism: link to Down syndrome?
V. O'Leary, A. Parle‐McDermott, A. Molloy, P. Kirke +4 more
2002American journal of medical genetics183 citations Open access
Semantic Scholar
A randomised trial of low dose folic acid to prevent neural tube defects. The Irish Vitamin Study Group.
P. Kirke, Leslie Daly, J. Elwood
1992Archives of Disease in Childhood181 citations Open access
Semantic Scholar
Impact of the MTHFR C677T polymorphism on risk of neural tube defects: case-control study
P. Kirke, J. Mills, A. Molloy, L. Brody +7 more
2004British medical journal145 citations Open access
Semantic Scholar
Confirmation of the R653Q polymorphism of the trifunctional C1-synthase enzyme as a maternal risk for neural tube defects in the Irish population
A. Parle‐McDermott, P. Kirke, J. Mills, A. Molloy +7 more
2006European Journal of Human Genetics118 citations Open access
Semantic Scholar
Choline and homocysteine interrelations in umbilical cord and maternal plasma at delivery.
A. Molloy, J. Mills, Christopher Cox, S. Daly +5 more
2005American Journal of Clinical Nutrition111 citations Open access
Semantic Scholar
Folic acid metabolism and mechanisms of neural tube defects.
J. M. Scott, D. Weir, Anne M. Molloy, J. Mcpartlin +2 more
2007Ciba Foundation symposium107 citations
Semantic Scholar
Linkage analysis identifies a locus for plasma von Willebrand factor undetected by genome-wide association
K. Desch, A. B. Ozel, D. Siemieniak, Yossi Kalish +18 more
2012Proceedings of the National Academy of Sciences of the United States of America101 citations Open access
Semantic Scholar
Maternal serum folate and vitamin B12 concentrations in pregnancies associated with neural tube defects.
Anne M. Molloy, P. Kirke, I. Hillary, D. Weir +1 more
1985Archives of Disease in Childhood96 citations Open access
Semantic Scholar
The Search for Genetic Polymorphisms in the Homocysteine/Folate Pathway That Contribute to the Etiology of Human Neural Tube Defects
A. Molloy, L. Brody, J. Mills, J. Scott +1 more
2009Birth defects research. Clinical and molecular teratology88 citations Open access
Semantic Scholar
Folate-Related Gene Polymorphisms as Risk Factors for Cleft Lip and Cleft Palate
J. Mills, A. Molloy, A. Parle‐McDermott, J. Troendle +11 more
2008Birth defects research. Clinical and molecular teratology87 citations Open access
Semantic Scholar
Maternal and fetal plasma homocysteine concentrations at birth: the influence of folate, vitamin B12, and the 5,10-methylenetetrahydrofolate reductase 677C-->T variant.
A. Molloy, J. Mills, J. Mcpartlin, P. Kirke +2 more
2002American Journal of Obstetrics and Gynecology86 citations
Semantic Scholar
Low blood folates in NTD pregnancies are only partly explained by thermolabile 5,10-methylenetetrahydrofolate reductase: low folate status alone may be the critical factor.
Anne M. Molloy, James L. Mills, P. Kirke, D. Ramsbottom +6 more
1998American journal of medical genetics84 citations
Semantic Scholar
Methylenetetrahydrofolate reductase mutation and neural tube defects.
P. Kirke, J. Mills, A. Whitehead, A. Molloy +1 more
1996The Lancet83 citations
Semantic Scholar
Evaluation of common genetic variants in 82 candidate genes as risk factors for neural tube defects
F. Pangilinan, A. Molloy, J. Mills, J. Troendle +17 more
2012BMC Medical Genetics82 citations Open access
Semantic Scholar
Whole-blood folate values in subjects with different methylenetetrahydrofolate reductase genotypes: differences between the radioassay and microbiological assays.
A. Molloy, J. Mills, P. Kirke, A. Whitehead +2 more
1998Clinical Chemistry76 citations
Semantic Scholar
Analysis of methionine synthase reductase polymorphisms for neural tube defects risk association.
V. O'Leary, J. Mills, F. Pangilinan, P. Kirke +9 more
2005Molecular Genetics and Metabolism74 citations
Semantic Scholar
The role of nutrition in neural tube defects.
J. M. Scott, P. Kirke, D. Weir
1990Annual review of nutrition71 citations
Semantic Scholar
Testing reported associations of genetic risk factors for oral clefts in a large Irish study population
Tonia C. Carter, A. Molloy, F. Pangilinan, J. Troendle +10 more
2009Birth defects research. Clinical and molecular teratology69 citations Open access
Semantic Scholar
A Common Variant in MTHFD1L is Associated with Neural Tube Defects and mRNA Splicing Efficiency
A. Parle‐McDermott, F. Pangilinan, Kirsty K. O’Brien, James L. Mills +7 more
2009Human Mutation69 citations Open access
Semantic Scholar
Analysis of the MTHFR 1298A→C and 677C→T polymorphisms as risk factors for neural tube defects
A. Parle‐McDermott, J. Mills, P. Kirke, V. O'Leary +7 more
2003Journal of Human Genetics67 citations
Semantic Scholar
A polymorphism in the MTHFD1 gene increases a mother's risk of having an unexplained second trimester pregnancy loss.
A. Parle‐McDermott, F. Pangilinan, J. Mills, C. Signore +7 more
2005Molecular human reproduction66 citations Open access
Semantic Scholar
Hidradenitis suppurativa. Glucose tolerance, clinical, microbiologic, and immunologic features and HLA frequencies in 27 patients.
S. O'Loughlin, R. Woods, P. Kirke, Fergus Shanahan +2 more
1988Archives of Dermatology61 citations
Semantic Scholar
The MTHFR 1298CC and 677TT genotypes have opposite associations with red cell folate levels.
A. Parle‐McDermott, J. Mills, A. Molloy, Nicola Carroll +6 more
2006Molecular Genetics and Metabolism55 citations
Semantic Scholar
Outcome of hip fracture in older Irish women: a 2-year follow-up of subjects in a case-control study.
P. Kirke, M. Sutton, Helen Burke, L. Daly
2002Injury48 citations
Semantic Scholar
Do high blood folate concentrations exacerbate metabolic abnormalities in people with low vitamin B-12 status?
J. Mills, Tonia C. Carter, J. Scott, J. Troendle +6 more
2011American Journal of Clinical Nutrition47 citations Open access
Semantic Scholar
Reduced folate carrier polymorphisms and neural tube defect risk.
V. O'Leary, F. Pangilinan, Christopher Cox, A. Parle‐McDermott +6 more
2006Molecular Genetics and Metabolism46 citations
Semantic Scholar
Lack of Association between Folate-Receptor Autoantibodies and Neural-Tube Defects
A. Molloy, E. Quadros, J. M. Sequeira, J. Troendle +3 more
2009New England Journal of Medicine45 citations Open access
Semantic Scholar
Transcobalamin II Receptor Polymorphisms Are Associated with Increased Risk for Neural Tube Defects
F. Pangilinan, A. Mitchell, J. Vandermeer, A. Molloy +9 more
2010Journal of Medical Genetics40 citations Open access
Semantic Scholar
Survival and disability in a cohort of neural tube defect births in Dublin, Ireland.
M. Sutton, L. Daly, P. Kirke
2008Birth defects research. Clinical and molecular teratology40 citations
Semantic Scholar
Evaluation of transcobalamin II polymorphisms as neural tube defect risk factors in an Irish population.
D. A. Swanson, F. Pangilinan, J. Mills, P. Kirke +11 more
2005Birth defects research. Clinical and molecular teratology37 citations
Semantic Scholar
MOTHERS' VIEWS OF OBSTETRIC CARE
P. Kirke
1980British Journal of Obstetrics and Gynaecology37 citations
Semantic Scholar
Analysis of the MTHFD1 promoter and risk of neural tube defects
Nicola Carroll, F. Pangilinan, A. Molloy, J. Troendle +5 more
2009Human Genetics36 citations Open access
Semantic Scholar
Methionine synthase: high-resolution mapping of the human gene and evaluation as a candidate locus for neural tube defects.
Lawrence C. Brody, Priscilla J. Baker, P. Chines, A. Musick +6 more
1999Molecular Genetics and Metabolism35 citations
Semantic Scholar
Maternal choline concentrations during pregnancy and choline-related genetic variants as risk factors for neural tube defects.
J. Mills, R. Fan, L. Brody, Ai-Yi Liu +5 more
2014American Journal of Clinical Nutrition31 citations Open access
Semantic Scholar
Predictors of first hip fracture and mortality post fracture in older women
P. Fitzpatrick, P. Kirke, Leslie E. Daly, I. V. van Rooij +5 more
2001Irish Journal of Medical Science31 citations
Semantic Scholar
Analysis of the human folate receptor beta gene for an association with neural tube defects.
V. O'Leary, J. Mills, P. Kirke, A. Parle‐McDermott +9 more
2003Molecular Genetics and Metabolism30 citations
Semantic Scholar
Evaluation of quantitative CT vertebral bone mineral density measurement and the Singh index in elderly females with hip fractures--a case control study.
J. Heneghan, P. Kirke, B. Murphy, E. Darcy +4 more
1997British Journal of Radiology27 citations
Semantic Scholar
Construction of a High Resolution Linkage Disequilibrium Map to Evaluate Common Genetic Variation in TP53 and Neural Tube Defect Risk in an Irish Population
F. Pangilinan, Kerry A Geiler, Jessica Dolle, J. Troendle +8 more
2008American Journal of Medical Genetics. Part A25 citations Open access
Semantic Scholar
MOTHERS'VIEWS OF CARE IN LABOUR
P. Kirke
1980British Journal of Obstetrics and Gynaecology25 citations
Semantic Scholar
The role of folate in the prevention of neural-tube defects
J. Scott, P. Kirke, A. Molloy, L. Daly +1 more
1994Proceedings of the Nutrition Society23 citations Open access
Semantic Scholar

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A. Molloy×35
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A. Molloy — researcher profile on SciRah
J. Scott×31
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J. Mills×31
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F. Pangilinan×15

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Christopher Cox×10

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V. O'Leary — researcher profile on SciRah

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J. Troendle — researcher profile on SciRah

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Helen Burke — researcher profile on SciRah

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D. Weir — researcher profile on SciRah