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M. Kriegs · SciRah

Researcher profile · Semantic Scholar

M. Kriegs

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M. Kriegs — researcher profile on SciRah

h-index: 24
Works: 115
Citations: 2,157

Most-cited papers

HNSCC cell lines positive for HPV and p16 possess higher cellular radiosensitivity due to an impaired DSB repair capacity.
T. Rieckmann, S. Tribius, T. Grob, F. Meyer +4 more
2013Radiotherapy and Oncology341 citations
Semantic Scholar
Cetuximab Resistance in Head and Neck Cancer Is Mediated by EGFR-K521 Polymorphism.
Friederike Braig, M. Kriegs, M. Voigtlaender, B. Habel +19 more
2017Cancer Research73 citations Open access
Semantic Scholar
Liquid biopsy monitoring uncovers acquired RAS-mediated resistance to cetuximab in a substantial proportion of patients with head and neck squamous cell carcinoma
Friederike Braig, M. Voigtlaender, Aneta Schieferdecker, C. Busch +6 more
2016OncoTarget70 citations Open access
Semantic Scholar
Epidermal growth factor receptor mutation mediates cross-resistance to panitumumab and cetuximab in gastrointestinal cancer
Friederike Braig, Manuela März, Aneta Schieferdecker, A. Schulte +14 more
2015OncoTarget69 citations Open access
Semantic Scholar
EGFRvIII upregulates DNA mismatch repair resulting in increased temozolomide sensitivity of MGMT promoter methylated glioblastoma
N. Struve, Zev A. Binder, Lucy F. Stead, T. Brend +18 more
2020Oncogene58 citations Open access
Semantic Scholar
The inhibition of PARP but not EGFR results in the radiosensitization of HPV/p16-positive HNSCC cell lines.
Julian David Güster, S. Weissleder, C. Busch, M. Kriegs +4 more
2014Radiotherapy and Oncology57 citations
Semantic Scholar
Radiosensitization of NSCLC cells by EGFR inhibition is the result of an enhanced p53-dependent G1 arrest.
M. Kriegs, K. Gurtner, Y. Can, I. Brammer +12 more
2015Radiotherapy and Oncology56 citations
Semantic Scholar
A Subset of Histone H2B Genes Produces Polyadenylated mRNAs under a Variety of Cellular Conditions
V. Kari, O. Karpiuk, Bettina Tieg, M. Kriegs +4 more
2013PLoS ONE51 citations Open access
Semantic Scholar
Analyzing expression and phosphorylation of the EGF receptor in HNSCC
M. Kriegs, T. Clauditz, K. Hoffer, J. Bartels +11 more
2019Scientific Reports46 citations Open access
Semantic Scholar
G2-checkpoint targeting and radiosensitization of HPV/p16-positive HNSCC cells through the inhibition of Chk1 and Wee1.
C. Busch, Marie Sophie Kröger, Jana Jensen, M. Kriegs +5 more
2016Radiotherapy and Oncology45 citations
Semantic Scholar
HPV-positive HNSCC cell lines but not primary human fibroblasts are radiosensitized by the inhibition of Chk1.
C. Busch, M. Kriegs, Simon Laban, S. Tribius +4 more
2013Radiotherapy and Oncology42 citations
Semantic Scholar
Sorafenib sensitizes head and neck squamous cell carcinoma cells to ionizing radiation.
Simon Laban, Leonhard Steinmeister, Lisa Gleißner, T. Grob +6 more
2013Radiotherapy and Oncology38 citations
Semantic Scholar
Axitinib: A Photoswitchable Approved Tyrosine Kinase Inhibitor
Dorian Schmidt, Theo Rodat, Linda Heintze, Jantje Weber +7 more
2018ChemMedChem32 citations
Semantic Scholar
Similar cisplatin sensitivity of HPV-positive and -negative HNSCC cell lines
C. Busch, Benjamin Becker, M. Kriegs, Fruzsina Gatzemeier +7 more
2016OncoTarget31 citations Open access
Semantic Scholar
Light-controlled inhibition of BRAFV600E kinase.
Mark W. H. Hoorens, M. Ourailidou, Theo Rodat, Petra E. van der Wouden +6 more
2019European journal of medicinal chemistry28 citations Open access
Semantic Scholar
Clustered localization of EGFRvIII in glioblastoma cells as detected by high precision localization microscopy.
Philip S. Boyd, N. Struve, Margund Bach, J. Eberle +5 more
2016Nanoscale24 citations Open access
Semantic Scholar
p53 modulates homologous recombination at I-SceI-induced double-strand breaks through cell-cycle regulation
T. Rieckmann, M. Kriegs, L. Nitsch, K. Hoffer +6 more
2013Oncogene23 citations
Semantic Scholar
Efficacy and Mechanism of Action of Marine Alkaloid 3,10-Dibromofascaplysin in Drug-Resistant Prostate Cancer Cells
S. Dyshlovoy, Moritz Kaune, Jessica Hauschild, M. Kriegs +12 more
2020Marine Drugs22 citations Open access
Semantic Scholar
Improving the Efficacy of Tumor Radiosensitization Through Combined Molecular Targeting
K. Hintelmann, M. Kriegs, K. Rothkamm, T. Rieckmann
2020Frontiers in Oncology22 citations Open access
Semantic Scholar
Photoswitchable Azo- and Diazocine-Functionalized Derivatives of the VEGFR-2 Inhibitor Axitinib
Linda Heintze, Dorian Schmidt, Theo Rodat, Lydia Witt +4 more
2020International Journal of Molecular Sciences21 citations Open access
Semantic Scholar
EGFRvIII does not affect radiosensitivity with or without gefitinib treatment in glioblastoma cells
N. Struve, Matthias Riedel, A. Schulte, T. Rieckmann +7 more
2015OncoTarget21 citations Open access
Semantic Scholar
The failure of cetuximab-based de-intensified regimes for HPV-positive OPSCC: A radiobiologists perspective
T. Rieckmann, M. Kriegs
2019Clinical and Translational Radiation Oncology20 citations Open access
Semantic Scholar
Radiosensitization of HNSCC cells by EGFR inhibition depends on the induction of cell cycle arrests
M. Kriegs, U. Kasten-Pisula, Britta Riepen, K. Hoffer +9 more
2016OncoTarget19 citations Open access
Semantic Scholar
Knockdown of AKT3 Activates HER2 and DDR Kinases in Bone-Seeking Breast Cancer Cells, Promotes Metastasis In Vivo and Attenuates the TGFβ/CTGF Axis
Nico Hinz, Anke Baranowsky, Michael Horn, M. Kriegs +6 more
2021Cells18 citations Open access
Semantic Scholar
Dual Inhibition of PARP and the Intra-S/G2 Cell Cycle Checkpoints Results in Highly Effective Radiosensitization of HPV-Positive HNSCC Cells
K. Hintelmann, T. Berenz, M. Kriegs, S. Christiansen +7 more
2021Frontiers in Oncology18 citations Open access
Semantic Scholar
Marine alkaloid monanchoxymycalin C: a new specific activator of JNK1/2 kinase with anticancer properties
S. Dyshlovoy, Moritz Kaune, M. Kriegs, Jessica Hauschild +8 more
2020Scientific Reports18 citations Open access
Semantic Scholar
A Synthetic Codon-Optimized Hepatitis C Virus Nonstructural 5A DNA Vaccine Primes Polyfunctional CD8+ T Cell Responses in Wild-Type and NS5A-Transgenic Mice
Fredrik Holmström, A. Pasetto, Veronica Nähr, A. Brass +6 more
2013Journal of Immunology18 citations Open access
Semantic Scholar
Mean global DNA methylation serves as independent prognostic marker in IDH wild type glioblastoma.
Alicia Eckhardt, R. Drexler, M. Schoof, N. Struve +14 more
2023Neuro-Oncology17 citations
Semantic Scholar
Effect of sorafenib on cisplatin-based chemoradiation in head and neck cancer cells
N. Möckelmann, T. Rieckmann, C. Busch, Benjamin Becker +11 more
2016OncoTarget17 citations Open access
Semantic Scholar
A Lack of Effectiveness in the ATM-Orchestrated DNA Damage Response Contributes to the DNA Repair Defect of HPV-Positive Head and Neck Cancer Cells
S. Köcher, H. Zech, L. Krug, Fruzsina Gatzemeier +10 more
2022Frontiers in Oncology16 citations Open access
Semantic Scholar
Patient derived ex vivo tissue slice cultures demonstrate a profound DNA double-strand break repair defect in HPV-positive oropharyngeal head and neck cancer.
H. Zech, J. Berger, W. Mansour, L. Nordquist +13 more
2022Radiotherapy and Oncology16 citations
Semantic Scholar
Combined Targeting of AKT and mTOR Inhibits Tumor Formation of EpCAM+ and CD90+ Human Hepatocellular Carcinoma Cells in an Orthotopic Mouse Model
M. Moustafa, Katarzyna-Krystyna Dähling, A. Günther, Leonie Riebandt +12 more
2022Cancers15 citations Open access
Semantic Scholar
Analyzing tyrosine kinase activity in head and neck cancer by functional kinomics: Identification of hyperactivated Src family kinases as prognostic markers and potential targets
L. Bussmann, K. Hoffer, Clara Marie von Bargen, C. Droste +29 more
2021International Journal of Cancer15 citations Open access
Semantic Scholar
Quantitative proteomics unveiled: Regulation of DNA double strand break repair by EGFR involves PARP1.
Laura Myllynen, M. Kwiatkowski, Lisa Gleißner, Britta Riepen +7 more
2015Radiotherapy and Oncology15 citations
Semantic Scholar
ATM is required for the repair of Topotecan-induced replication-associated double-strand breaks.
S. Köcher, Anja Spies-Naumann, M. Kriegs, J. Dahm-Daphi +1 more
2013Radiotherapy and Oncology15 citations
Semantic Scholar
Sorafenib inhibits cell growth but fails to enhance radio- and chemosensitivity of glioblastoma cell lines
Matthias Riedel, N. Struve, Justus M. Müller-Goebel, S. Köcher +4 more
2016OncoTarget14 citations Open access
Semantic Scholar
Inactivation of HNSCC Cells by 90Y-Labeled Cetuximab Strictly Depends on the Number of Induced DNA Double-Strand Breaks
Jarob Saker, M. Kriegs, M. Zenker, Jan-Martin Heldt +9 more
2013Journal of Nuclear Medicine14 citations Open access
Semantic Scholar
G2 checkpoint targeting via Wee1 inhibition radiosensitizes EGFRvIII-positive glioblastoma cells
Meryem H. Cetin, T. Rieckmann, K. Hoffer, Britta Riepen +10 more
2023Radiation Oncology13 citations Open access
Semantic Scholar
Mass Spectrometric Comparison of HPV-Positive and HPV-Negative Oropharyngeal Cancer
Marcus Wurlitzer, N. Moeckelmann, M. Kriegs, M. Vens +13 more
2020Cancers13 citations Open access
Semantic Scholar
Activation of Epidermal Growth Factor Receptor Sensitizes Glioblastoma Cells to Hypoxia-Induced Cell Death
Anna-Luisa Luger, Nadja I. Lorenz, H. Urban, I. Divé +12 more
2020Cancers12 citations Open access
Semantic Scholar
Spontaneous metastasis xenograft models link CD44 isoform 4 to angiogenesis, hypoxia, EMT and mitochondria‐related pathways in colorectal cancer
Arun Everest-Dass, S. Nersisyan, Hanna Maar, V. Novosad +18 more
2023Molecular Oncology11 citations Open access
Semantic Scholar
Cytotoxic N-Methylpretrichodermamide B Reveals Anticancer Activity and Inhibits P-Glycoprotein in Drug-Resistant Prostate Cancer Cells
S. Dyshlovoy, Tobias Busenbender, Jessica Hauschild, E. Girich +6 more
2022Marine Drugs11 citations Open access
Semantic Scholar
Increased replication stress and R-loop accumulation in EGFRvIII-expressing glioblastoma present new therapeutic opportunities
N. Struve, K. Hoffer, Anna-Sophie Weik, Britta Riepen +18 more
2021Neuro-Oncology Advances10 citations Open access
Semantic Scholar
Receptor tyrosine kinase MET as potential target of multi‐kinase inhibitor and radiosensitizer sorafenib in HNSCC
Kaweh Beizaei, Lisa Gleißner, K. Hoffer, L. Bussmann +8 more
2018Head and Neck10 citations Open access
Semantic Scholar
DNA Repair.
K. Borgmann, S. Köcher, M. Kriegs, W. Mansour +3 more
2016Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer10 citations
Semantic Scholar
Impaired DNA double-strand break repair and effective radiosensitization of HPV-negative HNSCC cell lines through combined inhibition of PARP and Wee1
A. Oetting, S. Christiansen, Fruzsina Gatzemeier, S. Köcher +11 more
2023Clinical and Translational Radiation Oncology9 citations Open access
Semantic Scholar
Novel preclinical gastroenteropancreatic neuroendocrine neoplasia models demonstrate the feasibility of mutation-based targeted therapy
F. Viol, B. Sipos, M. Fahl, T. Clauditz +7 more
2022Cellular Oncology9 citations Open access
Semantic Scholar
Ikaros sets the threshold for negative B-cell selection by regulation of the signaling strength of the AKT pathway
Patrick A. H. Ehm, Stefan Horn, K. Hoffer, M. Kriegs +6 more
2024Cell Communication and Signaling6 citations Open access
Semantic Scholar
Molecular targeting in combination with platinum‐based chemoradiotherapy in head and neck cancer treatment
N. Möckelmann, M. Kriegs, B. Lőrincz, C. Busch +1 more
2016Head and Neck6 citations Open access
Semantic Scholar
CDKL1 variants affecting ciliary formation predispose to thoracic aortic aneurysm and dissection
Theresa Nauth, Melanie Philipp, S. Renner, M. Burkhalter +23 more
2025Journal of Clinical Investigation5 citations
Semantic Scholar

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