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A. Chariot · SciRah

Researcher profile · Semantic Scholar

A. Chariot

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A. Chariot — researcher profile on SciRah

h-index: 49
Works: 147
Citations: 9,441

Most-cited papers

TLR-4, IL-1R and TNF-R signaling to NF-κB: variations on a common theme
L. Verstrepen, Tine Bekaert, Tieu-Lan Chau, J. Tavernier +2 more
2008Cellular and Molecular Life Sciences460 citations Open access
Semantic Scholar
Elongator controls the migration and differentiation of cortical neurons through acetylation of alpha-tubulin.
Catherine Creppe, L. Malinouskaya, Marie-Laure Volvert, M. Gillard +13 more
2009Cell433 citations Open access
Semantic Scholar
Codon-specific translation reprogramming promotes resistance to targeted therapy
F. Rapino, S. Delaunay, F. Rambow, Zhao-Li Zhou +25 more
2018Nature260 citations
Semantic Scholar
Are the IKKs and IKK-related kinases TBK1 and IKK-epsilon similarly activated?
Tieu-Lan Chau, Romain Gioia, J. Gatot, F. Patrascu +6 more
2008TIBS -Trends in Biochemical Sciences. Regular ed240 citations Open access
Semantic Scholar
A Dynamic Unfolded Protein Response Contributes to the Control of Cortical Neurogenesis.
S. Laguesse, Catherine Creppe, Danny D. Nedialkova, Pierre-Paul Prévôt +14 more
2015Developmental Cell210 citations Open access
Semantic Scholar
Transcription impairment and cell migration defects in elongator-depleted cells: implication for familial dysautonomia.
Pierre Close, Nicola A. Hawkes, Isabelle Cornez, Catherine Creppe +8 more
2006Molecules and Cells208 citations Open access
Semantic Scholar
EGFR and NF-κB: partners in cancer.
K. Shostak, A. Chariot
2015Trends in Molecular Medicine207 citations Open access
Semantic Scholar
Molecular Mechanisms Involved in Schwann Cell Plasticity
A. Boerboom, V. Dion, A. Chariot, Rachelle Franzen
2017Frontiers in Molecular Neuroscience185 citations Open access
Semantic Scholar
NF-κB, stem cells and breast cancer: the links get stronger
K. Shostak, A. Chariot
2011Breast Cancer Research174 citations Open access
Semantic Scholar
The NF-kappaB-independent functions of IKK subunits in immunity and cancer.
A. Chariot
2009Trends in Cell Biology172 citations
Semantic Scholar
Elp3 links tRNA modification to IRES-dependent translation of LEF1 to sustain metastasis in breast cancer
S. Delaunay, F. Rapino, L. Tharun, Zhao-Li Zhou +13 more
2016Journal of Experimental Medicine169 citations Open access
Semantic Scholar
The adaptor protein CIKS/Act1 is essential for IL-25-mediated allergic airway inflammation
E. Claudio, S. U. Sønder, Sun Saret, G. Carvalho +10 more
2009Journal of Immunology157 citations Open access
Semantic Scholar
Induction of nuclear factor-κB and its downstream genes by TNF-α and IL-1β has a pro-apoptotic role in pancreatic beta cells
F. Ortis, P. Pirot, N. Naamane, A. Kreins +8 more
2008Diabetologia125 citations Open access
Semantic Scholar
NF-κB-induced KIAA1199 promotes survival through EGFR signalling
K. Shostak, Xin Zhang, P. Hubert, S. Göktuna +11 more
2014Nature Communications115 citations Open access
Semantic Scholar
Molecular layers underlying cytoskeletal remodelling during cortical development.
J. Heng, A. Chariot, Laurent Nguyen
2010Trends in Neurosciences112 citations
Semantic Scholar
p27(Kip1) is a microtubule-associated protein that promotes microtubule polymerization during neuron migration.
J. Godin, Noémie Thomas, S. Laguesse, L. Malinouskaya +12 more
2012Developmental Cell106 citations Open access
Semantic Scholar
Role of IKK and ERK pathways in intrinsic inflammation of cystic fibrosis airways.
C. Verhaeghe, Caroline Remouchamps, B. Hennuy, A. Vanderplasschen +4 more
2007Biochemical Pharmacology102 citations
Semantic Scholar
Lipopolysaccharide-mediated Interferon Regulatory Factor Activation Involves TBK1-IKKϵ-dependent Lys63-linked Polyubiquitination and Phosphorylation of TANK/I-TRAF*
J. Gatot, Romain Gioia, Tieu-Lan Chau, F. Patrascu +9 more
2007Journal of Biological Chemistry99 citations Open access
Semantic Scholar
Elp3 drives Wnt-dependent tumor initiation and regeneration in the intestine
A. Ladang, F. Rapino, L. Heukamp, L. Tharun +16 more
2015Journal of Experimental Medicine90 citations Open access
Semantic Scholar
CEMIP (KIAA1199) induces a fibrosis-like process in osteoarthritic chondrocytes
C. Deroyer, E. Charlier, S. Neuville, O. Malaise +5 more
2019Cell Death and Disease85 citations Open access
Semantic Scholar
The emerging role of lysine acetylation of non-nuclear proteins
Pierre Close, Catherine Creppe, M. Gillard, A. Ladang +3 more
2010Cellular and Molecular Life Sciences82 citations Open access
Semantic Scholar
Downregulation of the FTO m6A RNA demethylase promotes EMT-mediated progression of epithelial tumors and sensitivity to Wnt inhibitors
J. Jeschke, É. Collignon, Clémence Al Wardi, Mohammad Krayem +34 more
2021Nature Cancer79 citations Open access
Semantic Scholar
Elongator subunit 3 (ELP3) modifies ALS through tRNA modification
A. Bento-Abreu, Gunilla Jäger, Bart Swinnen, Laura Rué +19 more
2018Human Molecular Genetics75 citations Open access
Semantic Scholar
MicroRNA targeting of CoREST controls polarization of migrating cortical neurons.
Marie-Laure Volvert, Pierre-Paul Prévôt, Pierre Close, S. Laguesse +12 more
2014Cell Reports66 citations Open access
Semantic Scholar
DBIRD integrates alternative mRNA splicing with RNA polymerase II transcript elongation
Pierre Close, P. East, A. B. Dirac-Svejstrup, Holger Hartmann +6 more
2012Nature66 citations Open access
Semantic Scholar
Targeting osteopontin suppresses glioblastoma stem‐like cell character and tumorigenicity in vivo
V. Lamour, Aurélie Henry, J. Kroonen, M. Nokin +11 more
2015International Journal of Cancer61 citations
Semantic Scholar
DERP6 (ELP5) and C3ORF75 (ELP6) Regulate Tumorigenicity and Migration of Melanoma Cells as Subunits of Elongator*
Pierre Close, M. Gillard, A. Ladang, Zhe-Shen Jiang +8 more
2012Journal of Biological Chemistry59 citations Open access
Semantic Scholar
Differential usage of NF‐κB activating signals by IL‐1β and TNF‐α in pancreatic beta cells
F. Ortis, M. Miani, M. Colli, D. Cunha +4 more
2012FEBS Letters59 citations Open access
Semantic Scholar
Elongator - an emerging role in neurological disorders.
Laurent Nguyen, S. Humbert, F. Saudou, A. Chariot
2010Trends in Molecular Medicine59 citations
Semantic Scholar
tRNA Modification: Is Cancer Having a Wobble?
F. Rapino, S. Delaunay, Zhao-Li Zhou, A. Chariot +1 more
2017Trends in Cancer52 citations
Semantic Scholar
Deregulated NF-κB activity in haematological malignancies
A. Keutgens, I. Robert, P. Viatour, A. Chariot
200647 citations
Semantic Scholar
Promoter-dependent Effect of IKKα on NF-κB/p65 DNA Binding*
G. Gloire, Julie Horion, N. El Mjiyad, F. Bex +3 more
2007Journal of Biological Chemistry45 citations Open access
Semantic Scholar
Matrix Metalloproteinase-9 gene induction by a truncated oncogenic NF-κB2 protein involves the recruitment of MLL1 and MLL2 H3K4 histone methyltransferase complexes
I. Robert, M. Aussems, A. Keutgens, Xin Zhang +10 more
2009Oncogene44 citations Open access
Semantic Scholar
Elp3‐mediated codon‐dependent translation promotes mTORC2 activation and regulates macrophage polarization
Dawei Chen, Ivan Nemazanyy, O. Peulen, K. Shostak +14 more
2022EMBO Journal42 citations Open access
Semantic Scholar
The Repressing Function of the Oncoprotein BCL-3 Requires CtBP, while Its Polyubiquitination and Degradation Involve the E3 Ligase TBLR1
A. Keutgens, K. Shostak, Pierre Close, Xin Zhang +7 more
2010Molecular and Cellular Biology42 citations Open access
Semantic Scholar
The Endosomal Protein CEMIP Links WNT Signaling to MEK1-ERK1/2 Activation in Selumetinib-Resistant Intestinal Organoids.
Hong-Quan Duong, Ivan Nemazanyy, F. Rambow, S. Tang +9 more
2018Cancer Research41 citations Open access
Semantic Scholar
Wobble tRNA modification and hydrophilic amino acid patterns dictate protein fate
F. Rapino, Zhao-Li Zhou, Ana Maria Roncero Sanchez, Marc Joiret +14 more
2021Nature Communications39 citations Open access
Semantic Scholar
The X-linked trichothiodystrophy-causing gene RNF113A links the spliceosome to cell survival upon DNA damage
K. Shostak, Zhe-Shen Jiang, B. Charloteaux, Alice Mayer +12 more
2020Nature Communications39 citations Open access
Semantic Scholar
Induction of the Alternative NF-κB Pathway by Lymphotoxin αβ (LTαβ) Relies on Internalization of LTβ Receptor
Corinne Ganeff, Caroline Remouchamps, L. Boutaffala, C. Bénézech +9 more
2011Molecular and Cellular Biology39 citations Open access
Semantic Scholar
Involvement of placental growth factor in Wallerian degeneration
L. Chaballe, Pierre Close, Maxime Sempels, S. Delstanche +6 more
2011Glia36 citations Open access
Semantic Scholar
Elongator controls cortical interneuron migration by regulating actomyosin dynamics
S. Tielens, Sandra Huysseune, J. Godin, A. Chariot +2 more
2016Cell Research35 citations Open access
Semantic Scholar
In Vitro cytotoxicity of some medicinal plants from Georgian Amaryllidaceae
Malkhaz Jokhadze, L. Éristavi, J. Kutchukhidze, A. Chariot +4 more
2007Phytotherapy Research35 citations
Semantic Scholar
BCL-3 Degradation Involves Its Polyubiquitination through a FBW7-independent Pathway and Its Binding to the Proteasome Subunit PSMB1*
A. Keutgens, Xin Zhang, K. Shostak, I. Robert +8 more
2010Journal of Biological Chemistry34 citations Open access
Semantic Scholar
Further Insights in the Mechanisms of Interleukin‐1β Stimulation of Osteoprotegerin in Osteoblast‐Like Cells
C. Lambert, C. Oury, E. Dejardin, A. Chariot +4 more
2007Journal of Bone and Mineral Research34 citations
Semantic Scholar
TNFα- and IKKβ-mediated TANK/I-TRAF phosphorylation: implications for interaction with NEMO/IKKγ and NF-κB activation
Marianne Bonif, M. Meuwis, Pierre Close, V. Benoit +7 more
200631 citations Open access
Semantic Scholar
Valine aminoacyl-tRNA synthetase promotes therapy resistance in melanoma
Najla El Hachem, Marine Leclercq, Miguel Susaeta Ruiz, Raphael Vanleyssem +19 more
2024Nature Cell Biology26 citations Open access
Semantic Scholar
IKKα Promotes Intestinal Tumorigenesis by Limiting Recruitment of M1-like Polarized Myeloid Cells
S. Göktuna, O. Canli, J. Bollrath, A. Fingerle +16 more
2014Cell Reports25 citations Open access
Semantic Scholar
Loss of tRNA-modifying enzyme Elp3 activates a p53-dependent antitumor checkpoint in hematopoiesis
Adeline Rosu, Najla El Hachem, F. Rapino, K. Rouault-Pierre +13 more
2021Journal of Experimental Medicine24 citations Open access
Semantic Scholar
The Prosurvival IKK-Related Kinase IKKε Integrates LPS and IL17A Signaling Cascades to Promote Wnt-Dependent Tumor Development in the Intestine.
S. Göktuna, K. Shostak, Tieu-Lan Chau, L. Heukamp +16 more
2016Cancer Research21 citations Open access
Semantic Scholar
KIAA1199: A novel regulator of MEK/ERK‐induced Schwann cell dedifferentiation
A. Boerboom, C. Reusch, Alexandra Pieltain, A. Chariot +1 more
2017Glia20 citations Open access
Semantic Scholar

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