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Longhou Fang · SciRah

Researcher profile · Semantic Scholar

Longhou Fang

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Longhou Fang — researcher profile on SciRah

h-index: 26
Works: 54
Citations: 2,933

Most-cited papers

Oxidation-Specific Epitopes are Danger Associated Molecular Patterns Recognized by Pattern Recognition Receptors of Innate Immunity
Y. Miller, Soo-Ho Choi, Philipp Wiesner, Longhou Fang +11 more
2011Circulation Research644 citations Open access
Semantic Scholar
Vascular lipid accumulation, lipoprotein oxidation and macrophage lipid uptake in hypercholesterolemic zebrafish
K. Stoletov, Longhou Fang, Soo-Ho Choi, K. Hartvigsen +10 more
2009Circulation Research263 citations Open access
Semantic Scholar
Control of Angiogenesis by AIBP-mediated Cholesterol Efflux
Longhou Fang, Soo-Ho Choi, J. Baek, Chao Liu +9 more
2013Nature199 citations Open access
Semantic Scholar
A visual–omics foundation model to bridge histopathology with spatial transcriptomics
Weiqing Chen, Pengzhi Zhang, T. Tran, Yiwei Xiao +16 more
2025Nature Methods151 citations Open access
Semantic Scholar
Lipoprotein modification and macrophage uptake: role of pathologic cholesterol transport in atherogenesis.
Y. Miller, Soo-Ho Choi, Longhou Fang, S. Tsimikas
2010Sub-cellular biochemistry149 citations
Semantic Scholar
Oxidative Stress Activates Endothelial Innate Immunity via Sterol Regulatory Element Binding Protein 2 (SREBP2) Transactivation of MiRNA-92a
Z. Chen, Liang Wen, Marcy Martin, Chien-Yi Hsu +14 more
2014Circulation144 citations Open access
Semantic Scholar
Zebrafish models of dyslipidemia: Relevance to atherosclerosis and angiogenesis
Longhou Fang, Chao Liu, Y. Miller
2013Translational Research: The Journal of Laboratory and Clinical Medicine118 citations Open access
Semantic Scholar
AIBP-mediated Cholesterol Efflux Instructs Hematopoietic Stem and Progenitor Cell Fate
Qilin Gu, Xiao-Jie Yang, Jie Lv, Jia-Xiong Zhang +18 more
2019Science117 citations Open access
Semantic Scholar
In vivo visualization and attenuation of oxidized lipid accumulation in hypercholesterolemic zebrafish.
Longhou Fang, S. Green, J. Baek, Sang-Hak Lee +6 more
2011Journal of Clinical Investigation97 citations Open access
Semantic Scholar
Oxidized Cholesteryl Esters and Phospholipids in Zebrafish Larvae Fed a High Cholesterol Diet
Longhou Fang, R. Harkewicz, K. Hartvigsen, Philipp Wiesner +9 more
2010Journal of Biological Chemistry85 citations Open access
Semantic Scholar
Tyrosine phosphorylated Par3 regulates epithelial tight junction assembly promoted by EGFR signaling
Yiguo Wang, Dan Du, Longhou Fang, Guang Yang +5 more
2006EMBO Journal85 citations Open access
Semantic Scholar
Apoc2 loss-of-function zebrafish mutant as a genetic model of hyperlipidemia
Chao Liu, Keith P. Gates, Longhou Fang, M. Amar +10 more
2015Disease Models & Mechanisms73 citations Open access
Semantic Scholar
Toll-like Receptor-4 and Lipoprotein Accumulation in Macrophages
Y. Miller, Soo-Ho Choi, Longhou Fang, R. Harkewicz
2009Trends in cardiovascular medicine73 citations Open access
Semantic Scholar
Emerging applications of zebrafish as a model organism to study oxidative mechanisms and their role in inflammation and vascular accumulation of oxidized lipids
Longhou Fang, Y. Miller
2012Free Radical Biology & Medicine66 citations Open access
Semantic Scholar
AIBP Limits Angiogenesis Through γ-Secretase-Mediated Upregulation of Notch Signaling
Renfang Mao, Shu Meng, Qilin Gu, R. Araujo-Gutierrez +9 more
2017Circulation Research64 citations Open access
Semantic Scholar
AIBP protects against metabolic abnormalities and atherosclerosis[S]
Dina A. Schneider, Soo-Ho Choi, Colin Agatisa-Boyle, Laurence Zhu +6 more
2018Journal of Lipid Research49 citations Open access
Semantic Scholar
AIBP augments cholesterol efflux from alveolar macrophages to surfactant and reduces acute lung inflammation.
Soo-Ho Choi, Aaron M. Wallace, Dina A. Schneider, Elianne Burg +7 more
2018JCI Insight46 citations Open access
Semantic Scholar
Ezetimibe and Simvastatin Reduce Cholesterol Levels in Zebrafish Larvae Fed a High-Cholesterol Diet
J. Baek, Longhou Fang, Andrew C. Li, Y. Miller
2012Cholesterol46 citations Open access
Semantic Scholar
Epigenetic landscape reveals MECOM as an endothelial lineage regulator
Jie Lv, Shu Meng, Qilin Gu, Rongbin Zheng +16 more
2023Nature Communications43 citations Open access
Semantic Scholar
Regulation of lipid rafts, angiogenesis and inflammation by AIBP
Longhou Fang, Y. Miller
2019Current Opinion in Lipidology42 citations Open access
Semantic Scholar
Hematopoiesis is regulated by cholesterol efflux pathways and lipid rafts: connections with cardiovascular diseases
Pooranee K. Morgan, Longhou Fang, G. Lancaster, A. Murphy
2019Journal of Lipid Research41 citations Open access
Semantic Scholar
TBX20 Regulates Angiogenesis through the PROK2-PROKR1 Pathway
Shu Meng, Qilin Gu, Xiao-Jie Yang, Jie Lv +5 more
2018Circulation40 citations Open access
Semantic Scholar
Proteomic, functional and motif‐based analysis of C‐terminal Src kinase‐interacting proteins
Guang Yang, Qingrun Li, Siyuan Ren, Xue-Feng Lu +8 more
2009Proteomics32 citations
Semantic Scholar
Free Cholesterol Bioavailability and Atherosclerosis
R. Abe, J. Abe, Minh-Thuy Nguyen, E. Olmsted-Davis +6 more
2022Current Atherosclerosis Reports30 citations Open access
Semantic Scholar
Cell polarity protein Par3 complexes with DNA-PK via Ku70 and regulates DNA double-strand break repair
Longhou Fang, Yiguo Wang, Dan Du, Guang Yang +5 more
2007Cell Research29 citations Open access
Semantic Scholar
Combination of apolipoprotein-A-I/apolipoprotein-A-I binding protein and anti-VEGF treatment overcomes anti-VEGF resistance in choroidal neovascularization in mice
Lingping Zhu, Mackenzie Parker, N. Enemchukwu, Megan Shen +5 more
2020Communications Biology28 citations Open access
Semantic Scholar
Lmo2 modulates Sphk1 and promotes endothelial cell migration
G. Matrone, Shu Meng, Qilin Gu, Jie Lv +3 more
2017Arteriosclerosis, Thrombosis and Vascular Biology25 citations Open access
Semantic Scholar
Cell polarity protein Par3 complexes with DNA-PK via Ku70 and regulates DNA double-strand break repair
Longhou Fang, Yiguo Wang, Dan Du, Guang Yang +5 more
2007Cell Research25 citations
Semantic Scholar
Polo-like kinase 2 regulates angiogenic sprouting and blood vessel development
Hongbo Yang, Longhou Fang, R. Zhan, J. M. Hegarty +6 more
2015Developmental Biology19 citations Open access
Semantic Scholar
A minimally invasive approach to induce myocardial infarction in mice without thoracotomy
Quan Sun, Kang-Kai Wang, Miao Pan, Ji-Peng Zhou +9 more
2018Journal of Cellular and Molecular Medicine17 citations Open access
Semantic Scholar
Systemic metabolite profiling reveals sexual dimorphism of AIBP control of metabolism in mice
Jun-Dae Kim, Lingping Zhu, Quan Sun, Longhou Fang
2021PLoS ONE13 citations Open access
Semantic Scholar
AIBP: A Novel Molecule at the Interface of Cholesterol Transport, Angiogenesis, and Atherosclerosis.
Laurence Zhu, Longhou Fang
2015Methodist DeBakey Cardiovascular Journal13 citations Open access
Semantic Scholar
Metabolic flexibility maintains proliferation and migration of FGFR signaling–deficient lymphatic endothelial cells
Hong-Yuan Song, Jie Zhu, Ping Li, Fei Han +2 more
2021Journal of Biological Chemistry12 citations Open access
Semantic Scholar
Targeted cholesterol efflux
Longhou Fang, Y. Miller
2013Cell Cycle10 citations Open access
Semantic Scholar
Proteome identification of binding-partners interacting with cell polarity protein Par3 in Jurkat cells.
Ying Zhou, Longhou Fang, Dan Du, Wenchao Zhou +4 more
2008Acta Biochimica et Biophysica Sinica10 citations
Semantic Scholar
AIBP, Angiogenesis, Hematopoiesis, and Atherogenesis
Xue-Ting Qiu, Jingmin Luo, Longhou Fang
2020Current Atherosclerosis Reports9 citations Open access
Semantic Scholar
Cholesterol-mediated regulation of angiogenesis: An emerging paradigm
Lingping Zhu, Qilin Gu, Longhou Fang
2019Cardiology Plus6 citations Open access
Semantic Scholar
APOA1 binding protein promotes lymphatic cell fate and lymphangiogenesis by relieving caveolae-mediated inhibition of VEGFR3 signaling
Jun-Dae Kim, Surbhi Chaudhary, Weiqing Chen, J. Astin +11 more
2025Nature Communications5 citations Open access
Semantic Scholar
A visual–omics foundation model to bridge histopathology image with transcriptomics
Weiqing Chen, Pengzhi Zhang, T. Tran, Yiwei Xiao +16 more
2025Research Square5 citations
Semantic Scholar
AIBP Regulates Metabolism of Ketone and Lipids but Not Mitochondrial Respiration
Jun-Dae Kim, Teng Zhou, Ai-Jun Zhang, Shu-Min Li +3 more
2022Cells5 citations Open access
Semantic Scholar
Erratum: Cell polarity protein Par3 complexes with DNA-PK via Ku70 and regulates DNA double-strand break repair (Cell Research (2007) 17 (100-116) DOI:10.1038/sj.cr.7310145)
Longhou Fang, Yiguo Wang, Dan Du, Guang Yang +5 more
20075 citations Open access
Semantic Scholar
Mitigating Vascular Inflammation by Mimicking AIBP Mechanisms: A New Therapeutic End for Atherosclerotic Cardiovascular Disease
Jun-Dae Kim, Abhishek Jain, Longhou Fang
2024International Journal of Molecular Sciences4 citations
Semantic Scholar
AIBP-LRP2–mediated HDL uptake restricts CXCR4+ stemlike capillary expansion and collateral circulation
Ling-Ping Zhu, Minghong Chen, Kechuan Lin, Can Du +14 more
2025Science Advances1 citations Open access
Semantic Scholar
AIBP-CAV1-VEGFR3 axis dictates lymphatic cell fate and controls lymphangiogenesis
Xiao-Jie Yang, Jun-Dae Kim, Kelvin Chan, Qilin Gu +6 more
2020bioRxiv1 citations Open access
Semantic Scholar
Flow Upregulated Scap Dictates Hematopoiesis
Longhou Fang
2024Blood0 citations
Semantic Scholar
Abstract 13674: AIBP-Mediated Cholesterol Efflux Controls Lymphangiogenesis
Jun-Dae Kim, Surbhi Chaudhary, Longhou Fang
2023Circulation0 citations
Semantic Scholar
Publisher Correction: Epigenetic landscape reveals MECOM as an endothelial lineage regulator
Jie Lv, Shu Meng, Qilin Gu, Rongbin Zheng +16 more
2023Nature Communications0 citations Open access
Semantic Scholar
FGFR Signaling Coordinates the Balance Between Glycolysis and Fatty Acid β-Oxidation in Lymphatic Endothelial Cells
Hong-Yuan Song, Jie Zhu, Longhou Fang, Pengchun Yu
2020bioRxiv0 citations Open access
Semantic Scholar
AIBP suppresses choroidal neovascularization (CNV) by enhancing cholesterol efflux
Ying-Bin Fu, Mackenzie Parker, Lingping Zhu, Qing Yan +3 more
20190 citations
Semantic Scholar
Abstract 14951: Discovery of a Novel Angiogenic Factor TBX20
Shu Meng, Qilin Gu, Xiao-Jie Yang, Jie Lv +5 more
20170 citations
Semantic Scholar

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