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G. Caldwell · SciRah

Researcher profile · Semantic Scholar

G. Caldwell

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G. Caldwell — researcher profile on SciRah

h-index: 54
Works: 167
Citations: 16K

Most-cited papers

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1
D. Klionsky, Amal Kamal Abdel-Aziz, Sara Abdelfatah, M. Abdellatif +496 more
2021Autophagy4,016 citations Open access
Semantic Scholar
Gaucher’s Disease Glucocerebrosidase and -synuclein form a bidirectional pathogenic loop in synucleinopathies
J. Mazzulli, You-hai Xu, Ying Sun, Adam L. Knight +5 more
2011Cell1,340 citations Open access
Semantic Scholar
Functional Links Between A# Toxicity, Endocytic Trafficking, and Alzheimer's Disease Risk Factors in Yeast
S. Treusch, S. Hamamichi, J. L. Goodman, Kent E. S. Matlack +19 more
2012391 citations
Semantic Scholar
Lysosomal Impairment in Parkinson’s Disease
B. Dehay, M. Martínez-Vicente, G. Caldwell, Kim A. Caldwell +5 more
2013Movement Disorders333 citations Open access
Semantic Scholar
Amelioration of Alzheimer’s disease pathology by mitophagy inducers identified via machine learning and a cross-species workflow
Cheng-Long Xie, Xu-Xu Zhuang, Zhangming Niu, Rui-Ting Ai +25 more
2022Nature Biomedical Engineering291 citations Open access
Semantic Scholar
Yeast reveal a “druggable” Rsp5/Nedd4 Network that Ameliorates α–Synuclein Toxicity in Neurons
D. Tardiff, N. Jui, V. Khurana, M. Tambe +10 more
2013Science268 citations Open access
Semantic Scholar
Potentiated Hsp104 variants antagonize diverse proteotoxic misfolding events
Meredith E. Jackrel, M. DeSantis, Bryan A. Martinez, L. Castellano +4 more
2013Cell243 citations Open access
Semantic Scholar
Dopamine induces soluble α-synuclein oligomers and nigrostriatal degeneration
Danielle E. Mor, E. Tsika, J. Mazzulli, Neal S. Gould +11 more
2017Nature Neuroscience214 citations Open access
Semantic Scholar
Compounds from an unbiased chemical screen reverse both ER-to-Golgi trafficking defects and mitochondrial dysfunction in Parkinson’s disease models
L. Su, P. K. Auluck, T. Outeiro, Esti Yeger-Lotem +15 more
2010Disease Models & Mechanisms198 citations Open access
Semantic Scholar
Clioquinol promotes the degradation of metal-dependent amyloid-β (Aβ) oligomers to restore endocytosis and ameliorate Aβ toxicity
Kent E. S. Matlack, D. Tardiff, Priyanka Narayan, S. Hamamichi +3 more
2014Proceedings of the National Academy of Sciences of the United States of America158 citations Open access
Semantic Scholar
C. elegans as a model organism to investigate molecular pathways involved with Parkinson's disease
A. J. Harrington, S. Hamamichi, G. Caldwell, Kim A. Caldwell
2010Developmental Dynamics149 citations
Semantic Scholar
Inhibitors of LRRK2 kinase attenuate neurodegeneration and Parkinson-like phenotypes in Caenorhabditis elegans and Drosophila Parkinson's disease models.
Zhao-Hui Liu, S. Hamamichi, B. Lee, De-Jun Yang +6 more
2011Human Molecular Genetics143 citations Open access
Semantic Scholar
TorsinA participates in endoplasmic reticulum-associated degradation
Flávia C. Nery, I. Armata, Jonathan E. Farley, Cho A. Jin +12 more
2011Nature Communications123 citations Open access
Semantic Scholar
Dysregulation of the Mitochondrial Unfolded Protein Response Induces Non-Apoptotic Dopaminergic Neurodegeneration in C. elegans Models of Parkinson's Disease
Bryan A. Martinez, D. Petersen, Anthony L. Gaeta, Samuel P. Stanley +2 more
2017Journal of Neuroscience122 citations Open access
Semantic Scholar
Modeling neurodegeneration in Caenorhabditis elegans
K. Caldwell, Corey W. Willicott, G. Caldwell
2020Disease Models & Mechanisms117 citations Open access
Semantic Scholar
Calcineurin determines toxic versus beneficial responses to α-synuclein
G. Caraveo, P. K. Auluck, L. Whitesell, C. Chung +12 more
2014Proceedings of the National Academy of Sciences of the United States of America116 citations Open access
Semantic Scholar
Mitochondrial dysfunction, oxidative stress, and neurodegeneration elicited by a bacterial metabolite in a C. elegans Parkinson's model
A. Ray, Bryan A. Martinez, Laura A. Berkowitz, G. Caldwell +1 more
2014Cell Death and Disease106 citations Open access
Semantic Scholar
The early-onset torsion dystonia-associated protein, torsinA, is a homeostatic regulator of endoplasmic reticulum stress response.
Pan Chen, Alexander J Burdette, J. C. Porter, J. Ricketts +7 more
2010Human Molecular Genetics103 citations Open access
Semantic Scholar
THE GLYCOLYTIC ENZYME, GPI-1, IS A FUNCTIONALLY CONSERVED MODIFIER OF DOPAMINERIGIC NEURODEGENERATION IN PARKINSON’S MODELS[GC1]
Adam L. Knight, Xiaohui Yan, S. Hamamichi, Rami R. Ajjuri +13 more
2014Cell Metabolism98 citations Open access
Semantic Scholar
Phosphatidylethanolamine deficiency disrupts α-synuclein homeostasis in yeast and worm models of Parkinson disease
Shao-Xiao Wang, Si-Yuan Zhang, L. Liou, Qun Ren +4 more
2014Proceedings of the National Academy of Sciences of the United States of America97 citations Open access
Semantic Scholar
The effects of pdr1, djr1.1 and pink1 loss in manganese-induced toxicity and the role of α-synuclein in C. elegans
J. Bornhorst, S. Chakraborty, S. Meyer, Hanna Lohren +8 more
2014Metallomics91 citations Open access
Semantic Scholar
Different 8-Hydroxyquinolines Protect Models of TDP-43 Protein, α-Synuclein, and Polyglutamine Proteotoxicity through Distinct Mechanisms
D. Tardiff, Michelle L. Tucci, K. Caldwell, G. Caldwell +1 more
2011Journal of Biological Chemistry81 citations Open access
Semantic Scholar
Low-Dose Bafilomycin Attenuates Neuronal Cell Death Associated with Autophagy-Lysosome Pathway Dysfunction
V. Pivtoraiko, A. J. Harrington, B. J. Mader, Austin M. Luker +4 more
2010Journal of Neurochemistry76 citations Open access
Semantic Scholar
Identification of novel ATP13A2 interactors and their role in α-synuclein misfolding and toxicity.
M. Usenovic, Adam L. Knight, A. Ray, Victoria Wong +5 more
2012Human Molecular Genetics74 citations Open access
Semantic Scholar
Functional Analysis of VPS41-Mediated Neuroprotection in Caenorhabditis elegans and Mammalian Models of Parkinson's Disease
A. J. Harrington, T. Yacoubian, Sunny R. Slone, K. Caldwell +1 more
2012Journal of Neuroscience72 citations Open access
Semantic Scholar
Genetic and Pharmacological Discovery for Alzheimer's Disease Using Caenorhabditis elegans.
Edward F. Griffin, K. Caldwell, G. Caldwell
2017ACS Chemical Neuroscience60 citations
Semantic Scholar
C. elegans as a model system to accelerate discovery for Parkinson disease.
Bryan A. Martinez, K. Caldwell, G. Caldwell
2017Current Opinion in Genetics and Development59 citations
Semantic Scholar
Protective Role of DNJ-27/ERdj5 in Caenorhabditis elegans Models of Human Neurodegenerative Diseases
F. Muñoz-Lobato, M. Rodríguez-Palero, Francisco Jose Naranjo-Galindo, F. Shephard +7 more
2014Antioxidants and Redox Signaling57 citations Open access
Semantic Scholar
Found in Translation: The Utility of C. elegans Alpha-Synuclein Models of Parkinson’s Disease
Anthony L. Gaeta, K. Caldwell, G. Caldwell
2019Brain Science56 citations Open access
Semantic Scholar
Chemical enhancement of torsinA function in cell and animal models of torsion dystonia
Songsong Cao, J. Hewett, F. Yokoi, Jun Lu +8 more
2010Disease Models & Mechanisms56 citations Open access
Semantic Scholar
Inhibitors of LRRK 2 kinase attenuate neurodegeneration and Parkinson-like phenotypes in Caenorhabditis elegans and Drosophila Parkinson ’ s disease models
Zhao-Hui Liu, S. Hamamichi, B. Lee, De-Jun Yang +6 more
201154 citations
Semantic Scholar
RTCB-1 Mediates Neuroprotection via XBP-1 mRNA Splicing in the Unfolded Protein Response Pathway
A. Ray, Si-Yuan Zhang, Courtney Rentas, K. Caldwell +1 more
2014Journal of Neuroscience49 citations Open access
Semantic Scholar
A Predictable Worm: Application of Caenorhabditis elegans for Mechanistic Investigation of Movement Disorders
P. M. Dexter, K. Caldwell, G. Caldwell
2012Neurotherapeutics49 citations Open access
Semantic Scholar
ApoE-associated modulation of neuroprotection from Aβ-mediated neurodegeneration in transgenic Caenorhabditis elegans
Edward F. Griffin, Samuel Scopel, Cayman A. Stephen, Adam C Holzhauer +5 more
2019Disease Models & Mechanisms47 citations Open access
Semantic Scholar
Neurodegenerative VPS41 variants inhibit HOPS function and mTORC1‐dependent TFEB/TFE3 regulation
R. V. D. van der Welle, R. Jobling, Christian H. Burns, P. Sanzà +22 more
2021EMBO Molecular Medicine45 citations Open access
Semantic Scholar
Glutaredoxin deficiency exacerbates neurodegeneration in C. elegans models of Parkinson's disease.
W. M. Johnson, Chen Yao, S. Siedlak, Wenzhang Wang +5 more
2015Human Molecular Genetics44 citations Open access
Semantic Scholar
The Small GTPase RAC1/CED-10 Is Essential in Maintaining Dopaminergic Neuron Function and Survival Against α-Synuclein-Induced Toxicity
H. Kim, C. Calatayud, Sanjib Guha, I. Fernández-Carasa +13 more
2018Molecular Neurobiology42 citations Open access
Semantic Scholar
Functional Links Between Aβ Toxicity, Endocytic Trafficking and Alzheimer’s Disease Risk Factors in Yeast
S. Treusch, S. Hamamichi, Jessica L. Goodman, Kent E. S. Matlack +17 more
2011Science40 citations Open access
Semantic Scholar
Cyclized NDGA modifies dynamic α-synuclein monomers preventing aggregation and toxicity
Malcolm J. Daniels, J. Nourse, H. Kim, Valerio Sainati +19 more
2019Scientific Reports38 citations Open access
Semantic Scholar
Alpha-synuclein inhibits Snx3–retromer-mediated retrograde recycling of iron transporters in S. cerevisiae and C. elegans models of Parkinson’s disease
Dhaval Patel, Chuan Xu, Sureshbabu Nagarajan, Zheng-Chang Liu +6 more
2018Human Molecular Genetics37 citations
Semantic Scholar
Modeling dopamine neuron degeneration in Caenorhabditis elegans.
Michelle L. Tucci, A. J. Harrington, G. Caldwell, K. Caldwell
2011Methods in molecular biology35 citations
Semantic Scholar
Gene-by-environment interactions that disrupt mitochondrial homeostasis cause neurodegeneration in C. elegans Parkinson’s models
H. Kim, Rylee J. Perentis, G. Caldwell, K. Caldwell
2018Cell Death and Disease34 citations Open access
Semantic Scholar
TorsinA rescues ER-associated stress and locomotive defects in C. elegans models of ALS
M. Thompson, Pan Chen, Xiaohui Yan, H. Kim +4 more
2013Disease Models & Mechanisms32 citations Open access
Semantic Scholar
Caenorhabditis elegans as a model system for identifying effectors of α-synuclein misfolding and dopaminergic cell death associated with Parkinson's disease.
A. J. Harrington, Adam L. Knight, G. Caldwell, K. Caldwell
2011Methods32 citations
Semantic Scholar
NCEH-1 modulates cholesterol metabolism and protects against &agr;-synuclein toxicity in a C. elegans model of Parkinson’s disease
Si-Yuan Zhang, S. A. Glukhova, K. Caldwell, G. Caldwell
2017Human Molecular Genetics31 citations Open access
Semantic Scholar
Distinct functional roles of Vps41‐mediated neuroprotection in Alzheimer's and Parkinson's disease models of neurodegeneration
Edward F. Griffin, Xiaohui Yan, K. Caldwell, G. Caldwell
2018Human Molecular Genetics30 citations Open access
Semantic Scholar
Valproic Acid Ameliorates C. elegans Dopaminergic Neurodegeneration with Implications for ERK-MAPK Signaling
Bwarenaba B. Kautu, A. Carrasquilla, Matthew L Hicks, K. Caldwell +1 more
2013Neuroscience Letters29 citations Open access
Semantic Scholar
henazine derivatives cause proteotoxicity and stress in C . elegans
R. Ray, Courtney Rentas, G. Caldwell, K. Caldwell
201427 citations
Semantic Scholar
Therapeutic genetic variation revealed in diverse Hsp104 homologs
Z. March, Katelyn M. Sweeney, H. Kim, Xiaohui Yan +13 more
2020bioRxiv26 citations Open access
Semantic Scholar
Genetic Defects in Mitochondrial Dynamics in Caenorhabditis elegans Impact Ultraviolet C Radiation- and 6-hydroxydopamine-Induced Neurodegeneration
Jessica H. Hartman, Claudia P. Gonzalez-Hunt, Samantha M. Hall, Ian Ryde +3 more
2019International Journal of Molecular Sciences25 citations Open access
Semantic Scholar

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