Skip to content

Home Search Authors Pakistan News Saved

SciRah

SciRah does not host or store research papers. Results come live from free, official scholarly APIs, and every paper links back to its original source.

Data sources

OpenAlex
Semantic Scholar
Crossref
CORE
arXiv
PubMed

Privacy policy Terms of service

G. Mearini · SciRah

Researcher profile · Semantic Scholar

G. Mearini

Share profile

G. Mearini — researcher profile on SciRah

h-index: 25
Works: 57
Citations: 2,402

Most-cited papers

Differentiation of cardiomyocytes and generation of human engineered heart tissue
K. Breckwoldt, David Letuffe-Brenière, I. Mannhardt, Thomas Schulze +18 more
2017Nature Protocols252 citations
Semantic Scholar
Cardiac myosin-binding protein C (MYBPC3) in cardiac pathophysiology
L. Carrier, G. Mearini, K. Stathopoulou, Friederike Cuello
2015Gene216 citations Open access
Semantic Scholar
Mybpc3 gene therapy for neonatal cardiomyopathy enables long-term disease prevention in mice
G. Mearini, D. Stimpel, B. Geertz, F. Weinberger +12 more
2014Nature Communications172 citations Open access
Semantic Scholar
Nonsense-Mediated mRNA Decay and Ubiquitin–Proteasome System Regulate Cardiac Myosin-Binding Protein C Mutant Levels in Cardiomyopathic Mice
N. Vignier, S. Schlossarek, B. Fraysse, G. Mearini +10 more
2009Circulation Research166 citations Open access
Semantic Scholar
The ubiquitin-proteasome system in cardiac dysfunction.
G. Mearini, S. Schlossarek, M. Willis, L. Carrier
2008Biochimica et Biophysica Acta158 citations Open access
Semantic Scholar
Endothelin‐1 Induces Myofibrillar Disarray and Contractile Vector Variability in Hypertrophic Cardiomyopathy–Induced Pluripotent Stem Cell–Derived Cardiomyocytes
Atsushi Tanaka, S. Yuasa, G. Mearini, Toru Egashira +15 more
2014Journal of the American Heart Association : Cardiovascular and Cerebrovascular Disease130 citations Open access
Semantic Scholar
Cardiac myosin-binding protein C in hypertrophic cardiomyopathy: mechanisms and therapeutic opportunities.
S. Schlossarek, G. Mearini, L. Carrier
2011Journal of Molecular and Cellular Cardiology121 citations Open access
Semantic Scholar
Disease modeling of a mutation in α‐actinin 2 guides clinical therapy in hypertrophic cardiomyopathy
M. Prondzynski, M. Lemoine, A. Zech, A. Horváth +21 more
2019EMBO Molecular Medicine111 citations Open access
Semantic Scholar
Rescue of cardiomyopathy through U7snRNA-mediated exon skipping in Mybpc3-targeted knock-in mice
C. Gedicke-Hornung, V. Behrens-Gawlik, S. Reischmann, B. Geertz +12 more
2013EMBO Molecular Medicine102 citations Open access
Semantic Scholar
Evaluation of MYBPC3 trans-Splicing and Gene Replacement as Therapeutic Options in Human iPSC-Derived Cardiomyocytes
M. Prondzynski, Elisabeth Krämer, S. Laufer, A. Shibamiya +10 more
2017Molecular Therapy: Nucleic Acids97 citations Open access
Semantic Scholar
Atrogin-1 and MuRF1 regulate cardiac MyBP-C levels via different mechanisms.
G. Mearini, C. Gedicke, S. Schlossarek, C. Witt +8 more
2010Cardiovascular Research95 citations Open access
Semantic Scholar
Repair of Mybpc3 mRNA by 5′-trans-splicing in a Mouse Model of Hypertrophic Cardiomyopathy
G. Mearini, D. Stimpel, Elisabeth Krämer, B. Geertz +10 more
2013Molecular Therapy: Nucleic Acids76 citations Open access
Semantic Scholar
Gene therapy strategies in the treatment of hypertrophic cardiomyopathy
M. Prondzynski, G. Mearini, L. Carrier
2018Pflügers Archiv: European Journal of Physiology63 citations
Semantic Scholar
Effects of Chronic Atrial Fibrillation on Active and Passive Force Generation in Human Atrial Myofibrils
A. Belus, N. Piroddi, C. Ferrantini, C. Tesi +10 more
2010Circulation Research58 citations Open access
Semantic Scholar
Comparison of the effects of a truncating and a missense MYBPC3 mutation on contractile parameters of engineered heart tissue.
P. Wijnker, F. Friedrich, A. Dutsch, S. Reischmann +6 more
2016Journal of Molecular and Cellular Cardiology54 citations
Semantic Scholar
Prevention of Myofilament Dysfunction by &bgr;-Blocker Therapy in Postinfarct Remodeling
D. Duncker, N. Boontje, D. Merkus, Amanda M. G. Versteilen +10 more
2009Circulation: Heart Failure49 citations Open access
Semantic Scholar
Adrenergic stress reveals septal hypertrophy and proteasome impairment in heterozygous Mybpc3-targeted knock-in mice
S. Schlossarek, F. Schuermann, B. Geertz, G. Mearini +2 more
2011Journal of Muscle Research and Cell Motility47 citations Open access
Semantic Scholar
Serum Matrix Metalloproteinases as Quantitative Biomarkers for Myocardial Fibrosis and Sudden Cardiac Death Risk Stratification in Patients With Hypertrophic Cardiomyopathy.
Julia Münch, M. Avanesov, P. Bannas, D. Säring +6 more
2016Journal of Cardiac Failure43 citations
Semantic Scholar
MYBPC3 in hypertrophic cardiomyopathy: from mutation identification to RNA-based correction
V. Behrens-Gawlik, G. Mearini, C. Gedicke-Hornung, P. Richard +1 more
2013Pflügers Archiv: European Journal of Physiology43 citations
Semantic Scholar
Targeted panel sequencing in pediatric primary cardiomyopathy supports a critical role of TNNI3
Jirko Kühnisch, C. Herbst, N. Al-Wakeel-Marquard, J. Dartsch +13 more
2019Clinical Genetics36 citations Open access
Semantic Scholar
Biallelic mutation in MYH7 and MYBPC3 leads to severe cardiomyopathy with left ventricular noncompaction phenotype
K. Kolokotronis, Jirko Kühnisch, E. Klopocki, J. Dartsch +7 more
2019Human Mutation35 citations
Semantic Scholar
Localization and dynamics of small circular DNA in live mammalian nuclei.
G. Mearini, P. Nielsen, F. O. Fackelmayer
2004Nucleic Acids Research33 citations Open access
Semantic Scholar
Enhanced myofilament responsiveness upon β-adrenergic stimulation in post-infarct remodeled myocardium.
N. Boontje, D. Merkus, R. Zaremba, Amanda M. G. Versteilen +10 more
2011Journal of Molecular and Cellular Cardiology31 citations Open access
Semantic Scholar
PITX2 Knockout Induces Key Findings of Electrical Remodeling as Seen in Persistent Atrial Fibrillation
C. Schulz, M. Lemoine, G. Mearini, J. Koivumäki +8 more
2023Circulation: Arrhythmia and Electrophysiology26 citations Open access
Semantic Scholar
Mechanical unloading of the rat heart involves marked changes in the protein kinase-phosphatase balance.
A. Schwoerer, C. Neuber, A. Schmechel, Ivan Melnychenko +7 more
2008Journal of Molecular and Cellular Cardiology26 citations
Semantic Scholar
Chronic Activation of Tubulin Tyrosination Improves Heart Function
Niels Pietsch, C. Y. Chen, S. Kupsch, Lucas Bacmeister +15 more
2024Circulation Research25 citations Open access
Semantic Scholar
ACTN2 Mutant Causes Proteopathy in Human iPSC-Derived Cardiomyocytes
A. Zech, M. Prondzynski, Sonia R. Singh, Niels Pietsch +21 more
2021bioRxiv20 citations Open access
Semantic Scholar
Cell Banking of hiPSCs: A Practical Guide to Cryopreservation and Quality Control in Basic Research.
A. Shibamiya, E. Schulze, D. Krauss, Christa Augustin +20 more
2020Current protocols in stem cell biology18 citations Open access
Semantic Scholar
Phosphomimetic cardiac myosin-binding protein C partially rescues a cardiomyopathy phenotype in murine engineered heart tissue
A. Dutsch, P. Wijnker, S. Schlossarek, F. Friedrich +9 more
2019Scientific Reports18 citations Open access
Semantic Scholar
Local Chromatin Mobility is Independent of Transcriptional Activity
G. Mearini, F. O. Fackelmayer
2006Cell Cycle12 citations Open access
Semantic Scholar
Analysis of Contractile Function of Permeabilized Human Hypertrophic Cardiomyopathy Multicellular Heart Tissue
Nico Kresin, Sabrina Stücker, Elisabeth Krämer, Frederik Flenner +6 more
2019Frontiers in Physiology10 citations Open access
Semantic Scholar
BSE-associated Prion-Amyloid Cardiomyopathy in Primates
S. Krasemann, G. Mearini, Elisabeth Krämer, Katja Wagenführ +8 more
2013Emerging Infectious Diseases10 citations Open access
Semantic Scholar
Piezo2 is not an indispensable mechanosensor in murine cardiomyocytes
B. Kloth, G. Mearini, F. Weinberger, J. Stenzig +7 more
2022Scientific Reports9 citations Open access
Semantic Scholar
Disease modeling of a mutation in α‐actinin 2 guides clinical therapy in hypertrophic cardiomyopathy
M. Prondzynski, M. Lemoine, A. Zech, A. Horváth +21 more
2022EMBO Molecular Medicine9 citations Open access
Semantic Scholar
The W101C KCNJ5 Mutation Induces Slower Pacing by Constitutively Active GIRK Channels in hiPSC-Derived Cardiomyocytes
Anne Kayser, S. Dittmann, T. Šarić, G. Mearini +2 more
2023International Journal of Molecular Sciences6 citations Open access
Semantic Scholar
Generation of bi-allelic MYBPC3 truncating mutant and isogenic control from an iPSC line of a patient with hypertrophic cardiomyopathy.
Nele Warnecke, Bärbel M. Ulmer, S. Laufer, A. Shibamiya +12 more
2021Stem Cell Research5 citations Open access
Semantic Scholar
Chronic activation of tubulin tyrosination in HCM mice and in human iPSC-engineered heart tissues improves heart function
Niels Pietsch, C. Y. Chen, S. Kupsch, L. Bacmeister +14 more
2023bioRxiv4 citations Open access
Semantic Scholar
Next-Generation Percutaneous Catheter–Based Closed-Loop Perfusion Concept Enables High-Precision Organ Delivery of Advanced Therapies
Maximilian Y. Emmert, J. Holzmeister, O. Blank, Heike Meyborg +14 more
2025JACC: Basic to Translational Science3 citations Open access
Semantic Scholar
Abstract 5292: Adrenergic Stress Unmasks Exaggerated Septal Hypertrophy and Proteasome Impairment in Heterozygous cMyBP-C Mutant Mice
F. Schuermann, S. Schlossarek, G. Mearini, B. Geertz +3 more
20083 citations
Semantic Scholar
Perinatal death in pig models of hypertrophic cardiomyopathy carrying sarcomere pathogenic variants
T. Flisikowska, Björn Petersen, G. Mearini, Daniela Huber +8 more
2025Journal of Molecular and Cellular Cardiology Plus2 citations Open access
Semantic Scholar
Generation of a patient-specific hiPS cell line with heterozygous GNB2 mutation (UKMi003-A) causative for human sinus node dysfunction and a corresponding CRISPR/Cas9-corrected isogenic control (UKMi004-A).
Anne Kayser, S. Dittmann, Jassin Hamidi, Sandra D. Laufer +4 more
2024Stem Cell Research2 citations Open access
Semantic Scholar
Author Correction: Differentiation of cardiomyocytes and generation of human engineered heart tissue
K. Breckwoldt, David Brenière-Letuffe, I. Mannhardt, Thomas Schulze +18 more
2019Nature Protocols2 citations Open access
Semantic Scholar
Abstract 918: Evidence of Alterations of the Ubiquitin-Proteasome System in Mouse Models of Familial Hypertrophic Cardiomyopathy
S. Schlossarek, N. Vignier, K. Sultan, Elisabeth Krämer +3 more
20062 citations
Semantic Scholar
Reducing microtubule detyrosination improves heart function in HCM mice and human iPSC-engineered heart tissues
Niels Pietsch, C. Y. Chen, S. Kupsch, L. Bacmeister +17 more
2 citations
Semantic Scholar
P236Evaluation of safety and feasibility of Mybpc3 gene therapy in a mouse model of hypertrophic cardiomyopathy
G. Mearini, D. Simpel, B. Geertz, L. Kraemer +5 more
20141 citations Open access
Semantic Scholar
Late-breaking Basic Science Abstracts from the American Heart Association's Scientific Sessions 2012 2012 Late-breaking Basic Science Abstracts Late-breaking Basic Science Oral Session 22925 Cardiac Myosin Binding Protein C Is an Ultra-early and Cardiac-specific Biomarker of Myocardial Necrosis Repl
Adriana Cardenas-Ospina, Lawson S. Miller, C. Troidl, H. Nef +17 more
20121 citations
Semantic Scholar
Oral abstract presentations & Young Investigators Competition
A. Leone, I. Aquila, C. Vicinanza, C. Iaconetti +145 more
20121 citations
Semantic Scholar
Nonsense-mediated mRNA decay degrades cMyBP-C mutants in cardiomyopathic mice
S. Schlossarek, N. Vignier, G. Mearini, J. Guiard +3 more
20071 citations
Semantic Scholar
Microtubule detyrosination regulates hiPSC-cardiomyocyte proliferation, autophagy, and hypertrophy
Niels Pietsch, Elisabeth Krämer, Eslem-Nur Yürümez, G. Mearini +4 more
2026Journal of Molecular and Cellular Cardiology Plus0 citations Open access
Semantic Scholar
Abstract 12927: Impact of AAV- MYBPC3 Gene Transfer on Heart Structure and Function in Human and Mouse Models of Hypertrophic Cardiomyopathy
Catherine Vitelli, Lening Zhang, R. Murphy, Bartlomiej Blus +17 more
2023Circulation0 citations
Semantic Scholar

Frequent co-authors

Invite them to SciRah by sharing their profile.

L. Carrier×30
Invite
L. Carrier — researcher profile on SciRah
T. Eschenhagen×26
Invite
T. Eschenhagen — researcher profile on SciRah
Elisabeth Krämer×20
Invite
Elisabeth Krämer — researcher profile on SciRah
S. Schlossarek×19
Invite
S. Schlossarek — researcher profile on SciRah

×12

Invite

B. Geertz — researcher profile on SciRah

Invite

I. Braren — researcher profile on SciRah

Invite

S. Laufer — researcher profile on SciRah

M. Prondzynski×7

Invite

M. Prondzynski — researcher profile on SciRah

Invite

A. Hansen — researcher profile on SciRah

Invite

T. Voit — researcher profile on SciRah

Julia Münch×6

Invite

Julia Münch — researcher profile on SciRah

J. van der Velden×6

Invite

J. van der Velden — researcher profile on SciRah