Skip to content

Home Search Authors Pakistan News Saved

SciRah

SciRah does not host or store research papers. Results come live from free, official scholarly APIs, and every paper links back to its original source.

Data sources

OpenAlex
Semantic Scholar
Crossref
CORE
arXiv
PubMed

Privacy policy Terms of service

Kyunghee Yang · SciRah

Researcher profile · Semantic Scholar

Kyunghee Yang

Share profile

Kyunghee Yang — researcher profile on SciRah

h-index: 19
Works: 31
Citations: 1,361

Most-cited papers

Risk Factors for Development of Cholestatic Drug-Induced Liver Injury: Inhibition of Hepatic Basolateral Bile Acid Transporters Multidrug Resistance-Associated Proteins 3 and 4
K. Köck, B. Ferslew, Ida Netterberg, Kyunghee Yang +4 more
2014Drug Metabolism And Disposition156 citations Open access
Semantic Scholar
Up-Regulation of UDP-Glucuronosyltransferase (UGT) 1A4 by 17β-Estradiol: A Potential Mechanism of Increased Lamotrigine Elimination in Pregnancy
Hui-Qing Chen, Kyunghee Yang, Suyoung Choi, J. Fischer +1 more
2009Drug Metabolism And Disposition151 citations Open access
Semantic Scholar
An Updated Review on Drug-Induced Cholestasis: Mechanisms and Investigation of Physicochemical Properties and Pharmacokinetic Parameters
Kyunghee Yang, K. Köck, Alexander Sedykh, A. Tropsha +1 more
2013Journal of Pharmacy and Science107 citations Open access
Semantic Scholar
Can Bile Salt Export Pump Inhibition Testing in Drug Discovery and Development Reduce Liver Injury Risk? An International Transporter Consortium Perspective
J. Kenna, Kunal S. Taskar, C. Battista, David L. Bourdet +14 more
2018Clinical pharmacology and therapy106 citations Open access
Semantic Scholar
Systems Pharmacology Modeling Predicts Delayed Presentation and Species Differences in Bile Acid-Mediated Troglitazone Hepatotoxicity
Kyunghee Yang, J. Woodhead, P. Watkins, B. Howell +1 more
2014Clinical pharmacology and therapy95 citations Open access
Semantic Scholar
Hepatic Basolateral Efflux Contributes Significantly to Rosuvastatin Disposition I: Characterization of Basolateral Versus Biliary Clearance Using a Novel Protocol in Sandwich-Cultured Hepatocytes
N. Pfeifer, Kyunghee Yang, K. Brouwer
2013Journal of Pharmacology and Experimental Therapeutics94 citations Open access
Semantic Scholar
Exploring BSEP inhibition-mediated toxicity with a mechanistic model of drug-induced liver injury
J. Woodhead, Kyunghee Yang, S. Siler, P. Watkins +3 more
2014Frontiers in Pharmacology87 citations Open access
Semantic Scholar
Sandwich-Cultured Hepatocytes as a Tool to Study Drug Disposition and Drug-Induced Liver Injury
Kyunghee Yang, Cen Guo, J. Woodhead, Robert LST. Claire +4 more
2016Journal of Pharmacy and Science73 citations Open access
Semantic Scholar
Estradiol induces cytochrome P450 2B6 expression at high concentrations: Implication in estrogen-mediated gene regulation in pregnancy
K. Koh, Steve J. Jurkovic, Kyunghee Yang, Suyoung Choi +4 more
2012Biochemical Pharmacology71 citations Open access
Semantic Scholar
Analyzing the Mechanisms Behind Macrolide Antibiotic-Induced Liver Injury Using Quantitative Systems Toxicology Modeling
J. Woodhead, Kyunghee Yang, D. Oldach, Chris MacLauchlin +4 more
2019Pharmaceutical Research53 citations Open access
Semantic Scholar
Species Differences in Hepatobiliary Disposition of Taurocholic Acid in Human and Rat Sandwich-Cultured Hepatocytes: Implications for Drug-Induced Liver Injury
Kyunghee Yang, N. Pfeifer, K. Köck, K. Brouwer
2015Journal of Pharmacology and Experimental Therapeutics53 citations Open access
Semantic Scholar
PS-052-End of study results from LIMT HDV study: 36% durable virologic response at 24 weeks post-treatment with pegylated interferon lambda monotherapy in patients with chronic hepatitis delta virus infection
O. Etzion, S. Hamid, Y. Lurie, E. Gane +11 more
2019Journal of Hepatology46 citations
Semantic Scholar
Systems pharmacology modeling of drug‐induced hyperbilirubinemia: Differentiating hepatotoxicity and inhibition of enzymes/transporters
Kyunghee Yang, C. Battista, J. Woodhead, S. Stahl +4 more
2017Clinical pharmacology and therapy43 citations Open access
Semantic Scholar
Mechanistic Modeling Reveals the Critical Knowledge Gaps in Bile Acid–Mediated DILI
J. Woodhead, Kyunghee Yang, K. R. Brouwer, S. Siler +5 more
2014CPT: Pharmacometrics & Systems Pharmacology43 citations Open access
Semantic Scholar
Considerations for Physiologically Based Modeling in Liver Disease: From Nonalcoholic Fatty Liver (NAFL) to Nonalcoholic Steatohepatitis (NASH)
William A. Murphy, Jeffry Adiwidjaja, Noora Sjöstedt, Kyunghee Yang +5 more
2022Clinical pharmacology and therapy31 citations Open access
Semantic Scholar
Isoform-specific regulation of cytochrome P450 expression and activity by estradiol in female rats
Suyoung Choi, L. Fischer, Kyunghee Yang, Hye J. Chung +1 more
2011Biochemical Pharmacology24 citations Open access
Semantic Scholar
Application of the DILIsym® Quantitative Systems Toxicology drug-induced liver injury model to evaluate the carcinogenic hazard potential of acetaminophen.
G. Eichenbaum, Kyunghee Yang, Y. Gebremichael, Brett A. Howell +8 more
2020Regulatory toxicology and pharmacology : RTP22 citations Open access
Semantic Scholar
Prediction of Altered Bile Acid Disposition Due to Inhibition of Multiple Transporters: An Integrated Approach Using Sandwich-Cultured Hepatocytes, Mechanistic Modeling, and Simulation
Cen Guo, Kyunghee Yang, Kenneth R. Brouwer, R. S. St. Claire +1 more
2016Journal of Pharmacology and Experimental Therapeutics21 citations Open access
Semantic Scholar
Induction of CYP2B6 and CYP3A4 by 1-Aminobenzotriazole (ABT) in Human Hepatocytes
Kyunghee Yang, K. Koh, Hyunyoung Jeong
2010Drug Metabolism Letters21 citations Open access
Semantic Scholar
Using Quantitative Systems Toxicology to Investigate Observed Species Differences in CKA-Mediated Hepatotoxicity
C. Battista, Kyunghee Yang, S. Stahl, J. Mettetal +3 more
2018Toxicological Sciences13 citations Open access
Semantic Scholar
Investigating bile acid-mediated cholestatic drug-induced liver injury using a mechanistic model of multidrug resistance protein 3 (MDR3) inhibition
J. Beaudoin, Kyunghee Yang, Jeffry Adiwidjaja, Guncha Taneja +4 more
2023Frontiers in Pharmacology11 citations Open access
Semantic Scholar
Hepatocellular Exposure of Troglitazone Metabolites in Rat Sandwich-Cultured Hepatocytes Lacking Bcrp and Mrp2: Interplay between Formation and Excretion
Kyunghee Yang, K. Brouwer
2014Drug Metabolism And Disposition9 citations Open access
Semantic Scholar
The Combination of a Human Biomimetic Liver Microphysiology System with BIOLOGXsym, a Quantitative Systems Toxicology (QST) Modeling Platform for Macromolecules, Provides Mechanistic Understanding of Tocilizumab- and GGF2-Induced Liver Injury
J. Beaudoin, Lara Clemens, Mark T. Miedel, Albert Gough +11 more
2023International Journal of Molecular Sciences8 citations Open access
Semantic Scholar
A critical review of the acetaminophen preclinical carcinogenicity and tumor promotion data and their implications for its carcinogenic hazard potential.
Jay Murray, Andrew D. Monnot, D. Jacobson-Kram, S. Cohen +15 more
2020Regulatory toxicology and pharmacology : RTP7 citations Open access
Semantic Scholar
An Experimental Approach To Evaluate the Impact of Impaired Transport Function on Hepatobiliary Drug Disposition Using Mrp2-Deficient TR– Rat Sandwich-Cultured Hepatocytes in Combination with Bcrp Knockdown
Kyunghee Yang, N. Pfeifer, Rhiannon N. Hardwick, W. Yue +2 more
2014Molecular Pharmaceutics7 citations Open access
Semantic Scholar
Prediction of Hepatic Efflux Transporter-mediated Drug Interactions: When is it Optimal to Measure Intracellular Unbound Fraction of Inhibitors?
Cen Guo, Kyunghee Yang, M. Liao, C. Xia +2 more
2017Journal of Pharmacy and Science5 citations Open access
Semantic Scholar
Analysis of Hepatic Transport Proteins
Kyunghee Yang, K. Köck, K. Brouwer
20133 citations
Semantic Scholar
Corrigendum: Considerations for Physiologically Based Modeling in Liver Disease: From Nonalcoholic Fatty Liver (NAFL) to Nonalcoholic Steatohepatitis (NASH)
William A. Murphy, Jeffry Adiwidjaja, Noora Sjöstedt, Kyunghee Yang +3 more
2023Clinical pharmacology and therapy2 citations Open access
Semantic Scholar
Mechanistic Modeling of Drug-Induced Liver Injury (DILI)
Kyunghee Yang, J. Woodhead, L. Shoda, Yu-Ching Yang +4 more
20150 citations
Semantic Scholar
Induction of CYP2B6 and CYP3A4 by 1-Aminobenzotriazole (ABT) in Human Hepatocytes
Kyunghee Yang, K. Koh, Hyunyoung Jeong
20130 citations
Semantic Scholar
Study on the Estrogenic Activity of Di-(2-Ethylhexyl) Adipate in E-Screen Assay and Uterotrophic Assay
S. Han, Hyung Sik Kim, Sangdon Han, R. Lee +2 more
20000 citations
Semantic Scholar

Frequent co-authors

Invite them to SciRah by sharing their profile.

K. Brouwer×12
Invite
K. Brouwer — researcher profile on SciRah
B. Howell×11
Invite
B. Howell — researcher profile on SciRah
S. Siler×11
Invite
S. Siler — researcher profile on SciRah
J. Woodhead×8
Invite
J. Woodhead — researcher profile on SciRah

×8

Invite

P. Watkins — researcher profile on SciRah

Hyunyoung Jeong×5

Invite

Hyunyoung Jeong — researcher profile on SciRah

Invite

K. Köck — researcher profile on SciRah

Invite

C. Battista — researcher profile on SciRah

K. R. Brouwer×4

Invite

K. R. Brouwer — researcher profile on SciRah

Invite

J. Beaudoin — researcher profile on SciRah

Suyoung Choi×3

Invite

Suyoung Choi — researcher profile on SciRah

Invite

N. Pfeifer — researcher profile on SciRah