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K. Komeda · SciRah

Researcher profile · Semantic Scholar

K. Komeda

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K. Komeda — researcher profile on SciRah

h-index: 25
Works: 76
Citations: 6,912

Most-cited papers

PPARγ Mediates High-Fat Diet–Induced Adipocyte Hypertrophy and Insulin Resistance
N. Kubota, Y. Terauchi, H. Miki, H. Tamemoto +24 more
19991,272 citations Open access
Semantic Scholar
Globular Adiponectin Protected ob/ob Mice from Diabetes and ApoE-deficient Mice from Atherosclerosis*
T. Yamauchi, J. Kamon, H. Waki, Y. Imai +20 more
2003Journal of Biological Chemistry970 citations Open access
Semantic Scholar
The Mechanisms by Which Both Heterozygous Peroxisome Proliferator-activated Receptor γ (PPARγ) Deficiency and PPARγ Agonist Improve Insulin Resistance*
T. Yamauchi, J. Kamon, H. Waki, K. Murakami +12 more
2001Journal of Biological Chemistry604 citations Open access
Semantic Scholar
Disruption of insulin receptor substrate 2 causes type 2 diabetes because of liver insulin resistance and lack of compensatory beta-cell hyperplasia.
N. Kubota, K. Tobe, Y. Terauchi, K. Eto +16 more
2000Diabetes546 citations Open access
Semantic Scholar
PPAR gamma mediates high-fat diet-induced adipocyte hypertrophy and insulin resistance.
N. Kubota, Y. Terauchi, H. Miki, H. Tamemoto +21 more
1999Molecules and Cells519 citations
Semantic Scholar
Glucokinase and IRS-2 are required for compensatory beta cell hyperplasia in response to high-fat diet-induced insulin resistance.
Y. Terauchi, Takamoto Iseki, N. Kubota, J. Matsui +16 more
2007Journal of Clinical Investigation332 citations Open access
Semantic Scholar
Inhibition of RXR and PPARgamma ameliorates diet-induced obesity and type 2 diabetes.
T. Yamauchi, H. Waki, J. Kamon, Koji Murakami +21 more
2001Journal of Clinical Investigation303 citations Open access
Semantic Scholar
The mechanisms by which both heterozygous peroxisome proliferator-activated receptor gamma (PPARgamma) deficiency and PPARgamma agonist improve insulin resistance.
T. Yamauchi, J. Kamon, H. Waki, K. Murakami +12 more
2001Journal of Biological Chemistry262 citations
Semantic Scholar
Pancreatic beta-cell-specific targeted disruption of glucokinase gene. Diabetes mellitus due to defective insulin secretion to glucose.
Y. Terauchi, H. Sakura, K. Yasuda, K. Iwamoto +16 more
1995Journal of Biological Chemistry218 citations Open access
Semantic Scholar
Essential Role of Insulin Receptor Substrate 1 (IRS-1) and IRS-2 in Adipocyte Differentiation
H. Miki, T. Yamauchi, Reiko Suzuki, K. Komeda +11 more
2001Molecular and Cellular Biology215 citations Open access
Semantic Scholar
A New Spontaneously Diabetic Non-obese Torii Rat Strain With Severe Ocular Complications
M. Shinohara, Taku Masuyama, T. Shoda, Tadakazu Takahashi +5 more
2000International Journal of Experimental Diabetes Research184 citations Open access
Semantic Scholar
Cblb is a major susceptibility gene for rat type 1 diabetes mellitus
N. Yokoi, K. Komeda, He-Yao Wang, H. Yano +6 more
2002Nature Genetics178 citations
Semantic Scholar
Increased insulin sensitivity despite lipodystrophy in Crebbp heterozygous mice
T. Yamauchi, Y. Oike, J. Kamon, H. Waki +13 more
2002Nature Genetics158 citations
Semantic Scholar
Development of non-insulin-dependent diabetes mellitus in the double knockout mice with disruption of insulin receptor substrate-1 and beta cell glucokinase genes. Genetic reconstitution of diabetes as a polygenic disease.
Y. Terauchi, K. Iwamoto, H. Tamemoto, K. Komeda +10 more
1997Journal of Clinical Investigation144 citations Open access
Semantic Scholar
Cyclic GMP-dependent protein kinase II is a molecular switch from proliferation to hypertrophic differentiation of chondrocytes.
H. Chikuda, F. Kugimiya, K. Hoshi, T. Ikeda +10 more
2004Genes & Development133 citations Open access
Semantic Scholar
Chronological characterization of diabetes development in male Spontaneously Diabetic Torii rats.
Taku Masuyama, K. Komeda, Akemi Hara, Mitsuhiko Noda +4 more
2004Biochemical and Biophysical Research Communications - BBRC124 citations
Semantic Scholar
Pioglitazone reduces islet triglyceride content and restores impaired glucose-stimulated insulin secretion in heterozygous peroxisome proliferator-activated receptor-gamma-deficient mice on a high-fat diet.
J. Matsui, Y. Terauchi, N. Kubota, Takamoto Iseki +8 more
2004Diabetes98 citations Open access
Semantic Scholar
Genetic analysis for diabetes in a new rat model of nonobese type 2 diabetes, Spontaneously Diabetic Torii rat.
Taku Masuyama, Masanori Fuse, N. Yokoi, M. Shinohara +5 more
2003Biochemical and Biophysical Research Communications - BBRC75 citations
Semantic Scholar
Establishment of two substrains, diabetes-prone and non-diabetic, from Long-Evans Tokushima Lean (LETL) rats.
K. Komeda, Mitsuhiko Noda, Keiji Terao, Nobuaki Kuzuya +2 more
1998Endocrine journal61 citations Open access
Semantic Scholar
A non-MHC locus essential for autoimmune type I diabetes in the Komeda Diabetes-Prone rat.
Norihide Yokoi, Masao Kanazawa, Kazuhiro Kitada, A. Tanaka +5 more
1997Journal of Clinical Investigation58 citations Open access
Semantic Scholar
Pdx1 Expression in Irs2-deficient Mouse β-Cells Is Regulated in a Strain-dependent Manner*
R. Suzuki, K. Tobe, Y. Terauchi, K. Komeda +15 more
2003Journal of Biological Chemistry30 citations Open access
Semantic Scholar
Increased serum leptin protects from adiposity despite the increased glucose uptake in white adipose tissue in mice lacking p85alpha phosphoinositide 3-kinase.
Y. Terauchi, J. Matsui, J. Kamon, T. Yamauchi +6 more
2004Diabetes29 citations Open access
Semantic Scholar
Impact of Genetic Background and Ablation of Insulin Receptor Substrate (IRS)-3 on IRS-2 Knock-out Mice*
Y. Terauchi, J. Matsui, R. Suzuki, N. Kubota +8 more
2003Journal of Biological Chemistry29 citations Open access
Semantic Scholar
The role of PPARγ as a thrifty gene both in mice and humans
K. Hara, N. Kubota, K. Tobe, Y. Terauchi +8 more
200028 citations Open access
Semantic Scholar
Non-obese-diabetic mice: immune mechanisms of pancreatic β-cell destruction
Yasunori Kanazawa, K. Komeda, S. Sato, S. Mori +2 more
1984Diabetologia28 citations Open access
Semantic Scholar
Pancreatic β-Cell-specific Targeted Disruption of Glucokinase Gene
Y. Terauchi, H. Sakura, K. Yasuda, K. Iwamoto +16 more
1995Journal of Biological Chemistry25 citations Open access
Semantic Scholar
Establishment and characterization of the Komeda diabetes-prone rat as a segregating inbred strain.
N. Yokoi, M. Namae, Masanori Fuse, He-Yao Wang +3 more
2003Experimental animals22 citations Open access
Semantic Scholar
New method for genotyping the mouse Lep(ob) mutation, using a polymerase chain reaction assay.
M. Namae, Y. Mori, K. Yasuda, Takashi Kadowaki +2 more
1998Laboratory animal science19 citations
Semantic Scholar
Appearance of a regenerating (reg) gene protein in pancreatic islets of remission BB/Wor//Tky rats.
C. Ishii, Shoji Kawazu, S. Tomono, T. Ohno +7 more
1993Endocrine journal18 citations Open access
Semantic Scholar
Diabetic syndrome in the Chinese hamster induced with monosodium glutamate
K. Komeda, M. Yokote, Y. Oki
1980Experientia18 citations
Semantic Scholar
Alteration of insulin and glucagon secretion from the perfused BB rat pancreas before and after the onset of diabetes.
M. Kanazawa, J. Ikeda, J. Sato, Yoko Natoya +4 more
1988Diabetes Research and Clinical Practice15 citations
Semantic Scholar
Phenotypic characterization of the Komeda miniature rat Ishikawa, an animal model of dwarfism caused by a mutation in Prkg2.
A. Tsuchida, N. Yokoi, M. Namae, Masanori Fuse +4 more
2008Comparative medicine13 citations
Semantic Scholar
Reciprocal changes in left ventricular collagen alpha 1 chain gene expression between types I and IV in spontaneously diabetic rats.
Shigehiro Katayama, Mari Abe, Kiyohiko Negishi, Keiichi Takahashi +2 more
1994Diabetes Research and Clinical Practice13 citations
Semantic Scholar
Spontaneous autoimmune thyroiditis in Bio Breeding/Worcester (BB/W) rat.
M. Yanagisawa, Yoshihito Hara, Kentaro Satoh, T. Tanikawa +5 more
1986Endocrinologia Japonica13 citations Open access
Semantic Scholar
35th Annual meeting of the European Association for the Study of Diabetes. Brussels, Belgium, 28 September-2 October, 1999. Abstracts.
A. Melander, J. Olsson, G. Lindberg, A. Salzman +496 more
1999Diabetologia12 citations
Semantic Scholar
Rat neurological disease creeping is caused by a mutation in the reelin gene.
N. Yokoi, M. Namae, He-Yao Wang, K. Kojima +5 more
2003Brain Research. Molecular Brain Research11 citations
Semantic Scholar
Comparative study on isolation calls emitted from hamster pups.
Haruo Hashimoto, Toru R. Saito, Naoki Moritani, K. Komeda +1 more
2001Experimental animals11 citations Open access
Semantic Scholar
Apolipoprotein E Metabolism in Sciatic Nerves of Diabetic Rats
S. Ishibashi, N. Mori, M. Shimada, T. Oka +7 more
1993Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme10 citations
Semantic Scholar
Hyperreninemia Due to Increased Renal Renin Synthesis in BioBreeding Worcester Rats
S. Katayamá, A. Omoto, Y. Maruno, M. Inaba +4 more
1990HYPERTENSION10 citations
Semantic Scholar
Administration of Optimum Sustained-Insulin Release PLGA Microcapsules to Spontaneous Diabetes-Prone BB/WorTky Rats
Mitsuko Takenaga, Y. Yamaguchi, Y. Ogawa, A. Kitagawa +5 more
2006Drug Delivery9 citations Open access
Semantic Scholar
Genetic mapping of the rat mutation creeping and evaluation of its positional candidate gene reelin
N. Yokoi, Seiko Shimizu, K. Ishibashi, K. Kitada +5 more
2000Mammalian Genome8 citations
Semantic Scholar
The role of PPARgamma as a thrifty gene both in mice and humans.
K. Hara, N. Kubota, K. Tobe, Y. Terauchi +8 more
2000British Journal of Nutrition8 citations
Semantic Scholar
Induction of alimentary diabetes and insulin responses to glucose in Microtus arvalis Pallas.
T. Arai, Minoru Sasaki, Y. Oki, K. Komeda
1985Nihon juigaku zasshi. The Japanese journal of veterinary science8 citations Open access
Semantic Scholar
Adenoviral insulin gene therapy prolongs survival of IDDM model BB rats by improving hyperlipidemia.
W. Zhang, D. Lu, S. Kawazu, K. Komeda +1 more
2002Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme7 citations
Semantic Scholar
An improved genetic linkage map of rat chromosome 20.
Taku Masuyama, J. Ishibiki, T. Awata, Mitsuhiko Noda +3 more
2000Comparative medicine7 citations
Semantic Scholar
Creeping: a new mutant rat with neurological disease.
K. Ishibashi, K. Komeda, F. Sekiguchi, Y. Kanazawa
1989Laboratory animal science6 citations
Semantic Scholar
Genetic and Physiological Control of Esterases in Experimental Small Animals IX. Influence of Gonadal Hormones on the Kidney Esterase Isoenzymes of Mice
K. Komeda, M. Manda, S. Nishida
19716 citations
Semantic Scholar
Beta-cell replication in insulin-induced remission of IDDM in BB/Wor//Tky rats
C. Ishiia, S. Kawazu, T. Utsugi, Y. Ito +6 more
19965 citations
Semantic Scholar
Plasma progesterone concentrations during the estrous cycle, pregnancy, and lactation in the Chinese hamster, Cricetulus griceus.
Toru Sato, K. Komeda, Kazuhiko Shirama
1984Jikken dobutsu. Experimental animals5 citations Open access
Semantic Scholar
An ultrastructural study on the pancreatic islet B cells in diabetic herbivorous voles
Minoru Sasaki, T. Arai, Y. Oki, K. Komeda
2004Veterinary research communications4 citations
Semantic Scholar

Frequent co-authors

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T. Kadowaki×18
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T. Kadowaki — researcher profile on SciRah
Y. Terauchi×17
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Y. Terauchi — researcher profile on SciRah
N. Kubota×15
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N. Kubota — researcher profile on SciRah
T. Yamauchi×15
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T. Yamauchi — researcher profile on SciRah

×12

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K. Tobe — researcher profile on SciRah

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H. Miki — researcher profile on SciRah

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R. Nagai — researcher profile on SciRah

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S. Kimura — researcher profile on SciRah

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K. Eto — researcher profile on SciRah

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J. Kamon — researcher profile on SciRah

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A. Tsuchida — researcher profile on SciRah

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Y. Kanazawa — researcher profile on SciRah