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K. Harigaya · SciRah

Researcher profile · Semantic Scholar

K. Harigaya

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K. Harigaya — researcher profile on SciRah

h-index: 31
Works: 121
Citations: 3,318

Most-cited papers

neurotic, a novel maternal neurogenic gene, encodes an O-fucosyltransferase that is essential for Notch-Delta interactions
Takeshi Sasamura, Nobuo Sasaki, Fumiyasu Miyashita, S. Nakao +8 more
2003Development180 citations
Semantic Scholar
Interleukin-11 as a Stimulatory Factor for Bone Formation Prevents Bone Loss with Advancing Age in Mice*
Y. Takeuchi, Sumiyo T. Watanabe, G. Ishii, S. Takeda +7 more
2002Journal of Biological Chemistry141 citations Open access
Semantic Scholar
The role of mel-18, a mammalian Polycomb group gene, during IL-7-dependent proliferation of lymphocyte precursors.
T. Akasaka, K. Tsuji, H. Kawahira, M. Kanno +7 more
1997Immunity140 citations Open access
Semantic Scholar
Chronic effects in mice caused by oral administration of sublethal doses of azaspiracid, a new marine toxin isolated from mussels.
E. Ito, M. Satake, Katsuya Ofuji, Morihiro Higashi +3 more
2002Toxicon138 citations
Semantic Scholar
A Human Protein with Sequence Similarity to DrosophilaMastermind Coordinates the Nuclear Form of Notch and a CSL Protein To Build a Transcriptional Activator Complex on Target Promoters
M. Kitagawa, Toshinao Oyama, T. Kawashima, B. Yedvobnick +3 more
2001Molecular and Cellular Biology134 citations Open access
Semantic Scholar
Nemo-like kinase suppresses Notch signalling by interfering with formation of the Notch active transcriptional complex
T. Ishitani, T. Hirao, Maho Suzuki, Miho Isoda +5 more
2010Nature Cell Biology130 citations Open access
Semantic Scholar
Identification of New Human Mastermind Proteins Defines a Family That Consists of Positive Regulators for Notch Signaling*
Sey-En Lin, Toshinao Oyama, T. Nagase, K. Harigaya +1 more
2002Journal of Biological Chemistry122 citations Open access
Semantic Scholar
CD44 signaling through focal adhesion kinase and its anti‐apoptotic effect
Y. Fujita, M. Kitagawa, Sukeyuki Nakamura, Kazuhiko Azuma +7 more
2002FEBS Letters118 citations
Semantic Scholar
Generation of functional clonal cell lines from human bone marrow stroma.
K. Harigaya, Hiroshi Handa
1985Proceedings of the National Academy of Sciences of the United States of America113 citations Open access
Semantic Scholar
An essential role of alternative splicing of c-myc suppressor FUSE-binding protein-interacting repressor in carcinogenesis.
K. Matsushita, T. Tomonaga, H. Shimada, A. Shioya +7 more
2006Cancer Research91 citations Open access
Semantic Scholar
Role of p27Kip1 and cyclin-dependent kinase 2 in the proliferation of non-small cell lung cancer.
Hidetada Kawana, J. Tamaru, Tomoaki Tanaka, Aizan Hirai +5 more
1998American Journal of Pathology91 citations Open access
Semantic Scholar
Hypermethylation of the CD44 gene is associated with progression and metastasis of human prostate cancer
Hiroki Kito, Hiroyoshi Suzuki, T. Ichikawa, Nobuyuki Sekita +7 more
2001The Prostate78 citations
Semantic Scholar
Mastermind-like 1 (MamL1) and mastermind-like 3 (MamL3) are essential for Notch signaling in vivo
Toshinao Oyama, K. Harigaya, Nobuo Sasaki, Yoshiaki Okamura +12 more
2011Development70 citations Open access
Semantic Scholar
Murine induced pluripotent stem cells can be derived from and differentiate into natural killer T cells.
H. Watarai, S. Fujii, D. Yamada, A. Rybouchkin +17 more
2010Journal of Clinical Investigation63 citations Open access
Semantic Scholar
Ang II-stimulated migration of vascular smooth muscle cells is dependent on LR11 in mice.
Mei-Zi Jiang, H. Bujo, K. Ohwaki, H. Unoki +7 more
2008Journal of Clinical Investigation63 citations Open access
Semantic Scholar
CD44 Suppresses TLR-Mediated Inflammation1
Hidetada Kawana, Hirokazu Karaki, Morihiro Higashi, M. Miyazaki +3 more
2008Journal of Immunology63 citations
Semantic Scholar
Notch deficiency implicated in the pathogenesis of congenital disorder of glycosylation IIc.
Hiroyuki O. Ishikawa, Shunsuke Higashi, T. Ayukawa, Takeshi Sasamura +6 more
2005Proceedings of the National Academy of Sciences of the United States of America58 citations Open access
Semantic Scholar
Introduction of autopsy imaging redefines the concept of autopsy: 37 cases of clinical experience
H. Ezawa, R. Yoneyama, S. Kandatsu, K. Yoshikawa +2 more
2003Pathology international (Print)58 citations Open access
Semantic Scholar
Mastermind-1 is required for Notch signal-dependent steps in lymphocyte development in vivo
Toshinao Oyama, K. Harigaya, Ablimit Muradil, K. Hozumi +8 more
2007Proceedings of the National Academy of Sciences of the United States of America51 citations Open access
Semantic Scholar
Colony-stimulating factor 1 expression is down-regulated during the adipocyte differentiation of H-1/A marrow stromal cells and induced by cachectin/tumor necrosis factor
A. Umezawa, K. Tachibana, K. Harigaya, S. Kusakari +3 more
1991Molecular and Cellular Biology51 citations Open access
Semantic Scholar
Tissue inhibitor of metalloproteinases from human bone marrow stromal cell line KM 102 has erythroid‐potentiating activity, suggesting its possibly bifunctional role in the hematopoietic microenvironment
T. Hayakawa, K. Yamashita, J. Kishi, K. Harigaya
1990FEBS Letters49 citations Open access
Semantic Scholar
In vivo and in vitro characterization of human fibroblasts recruited selectively into human cancer stroma
G. Ishii, T. Sangai, Takashi Ito, T. Hasebe +4 more
2005International Journal of Cancer47 citations Open access
Semantic Scholar
High CC chemokine receptor 7 expression improves postoperative prognosis of lung adenocarcinoma patients
M. Itakura, Y. Terashima, M. Shingyoji, S. Yokoi +12 more
2013British Journal of Cancer45 citations Open access
Semantic Scholar
Risk Factors in Chronic Subdural Hematoma: Comparison of Irrigation with Artificial Cerebrospinal Fluid and Normal Saline in a Cohort Analysis
Akihiko Adachi, Yoshinori Higuchi, A. Fujikawa, T. Machida +4 more
2014PLoS ONE37 citations Open access
Semantic Scholar
Interleukin 6 mediates production of interleukin 10 in metastatic melanoma
Mizue Terai, M. Eto, G. D. Young, D. Berd +4 more
2012Cancer Immunology and Immunotherapy37 citations Open access
Semantic Scholar
Aberrant expression of human ortholog of mammalian enabled (hMena) in human colorectal carcinomas: implications for its role in tumor progression.
Akihiro Toyoda, Hidetada Kawana, Kouji Azuhata, Jianyong Yu +4 more
2009International Journal of Oncology35 citations Open access
Semantic Scholar
Tumor necrosis factor and interleukin-1 induce activin A gene expression in a human bone marrow stromal cell line.
S. Takahashi, K. Uchimaru, K. Harigaya, S. Asano +1 more
1992Biochemical and Biophysical Research Communications - BBRC34 citations
Semantic Scholar
Binding of membrane-anchored macrophage colony-stimulating factor (M-CSF) to its receptor mediates specific adhesion between stromal cells and M-CSF receptor-bearing hematopoietic cells.
N. Uemura, K. Ozawa, Keisuke Takahashi, A. Tojo +8 more
1993Blood32 citations Open access
Semantic Scholar
Fibroblasts associated with cancer cells keep enhanced migration activity after separation from cancer cells: a novel character of tumor educated fibroblasts.
G. Ishii, H. Hashimoto, K. Asada, Takashi Ito +8 more
2010International Journal of Oncology31 citations Open access
Semantic Scholar
The Activity of RhoA is Correlated with Lymph Node Metastasis in Human Colorectal Cancer
Y. Takami, Morihiro Higashi, Shinpei Kumagai, Paul C. Kuo +4 more
2008Digestive Diseases and Sciences31 citations
Semantic Scholar
Retinoids (all-trans and 9-cis retinoic acid) stimulate production of macrophage colony-stimulating factor and granulocyte-macrophage colony-stimulating factor by human bone marrow stromal cells.
Hideaki Nakajima, M. Kizaki, A. Sonoda, S. Mori +2 more
1994Blood29 citations
Semantic Scholar
Fms-like tyrosine kinase 3 ligand stimulation induces MLL-rearranged leukemia cells into quiescence resistant to antileukemic agents.
Yoshiyuki Furuichi, K. Goi, T. Inukai, Hiroki Sato +12 more
2007Cancer Research28 citations
Semantic Scholar
Activation of mitogen-activated protein kinase through alpha5/beta1 integrin is required for cell cycle progression of B progenitor cell line, Reh, on human marrow stromal cells.
Ya-Wei Qiang, M. Kitagawa, Morihiro Higashi, G. Ishii +2 more
2000Experimental Hematology27 citations Open access
Semantic Scholar
Expression and localization of membrane-type-1 matrix metalloproteinase, CD 44, and laminin-5γ2 chain during colorectal carcinoma tumor progression
S. Murai, Toshifumi Umemiya, M. Seiki, K. Harigaya
2004Virchows Archiv25 citations
Semantic Scholar
Production of human granulocyte colony stimulating factor by various kinds of stromal cells in vitro detected by enzyme immunoassay and in situ hybridization
K. Watari, K. Ozawa, K. Tajika, A. Tojo +7 more
1994Stem Cells25 citations
Semantic Scholar
Fragmented hyaluronan is an autocrine chemokinetic motility factor supported by the HAS2-HYAL2/CD44 system on the plasma membrane.
Teruyoshi Saito, Hidetada Kawana, Kazuhiko Azuma, Akihiro Toyoda +3 more
2011International Journal of Oncology22 citations Open access
Semantic Scholar
Diffuse large B cell lymphoma expressing the natural killer cell marker CD56
T. Sekita, J. Tamaru, K. Isobe, K. Harigaya +4 more
1999Pathology international (Print)22 citations
Semantic Scholar
Gap-junctional communication of bone marrow stromal cells is resistant to irradiation in vitro.
Akihiro Umezawa, K. Harigaya, H. Abe, Y. Watanabe
1990Experimental Hematology21 citations
Semantic Scholar
A case report of undifferentiated carcinoma with osteoclast-like giant cells of the pancreas and literature review
Y. Togawa, A. Tonouchi, T. Chiku, W. Sano +8 more
2010Clinical Journal of Gastroenterology20 citations
Semantic Scholar
Enhancement of chemosensitivity toward peplomycin by calpastatin-stabilized NF-κB p65 in esophageal carcinoma cells: possible involvement of Fas/Fas-L synergism
Tian-Xiang Liu, Hideaki Shimada, T. Ochiai, T. Shiratori +8 more
2006Apoptosis20 citations
Semantic Scholar
Human Mena Associates with Rac1 Small GTPase in Glioblastoma Cell Lines
Morihiro Higashi, C. Ishikawa, Jianyong Yu, Akihiro Toyoda +5 more
2009PLoS ONE18 citations Open access
Semantic Scholar
V H Gene Analysis in Sporadic Burkitt's Lymphoma: Somatic Mutation and Intraclonal Diversity with Special Reference to the Tumor Cells Involving Germinal Center
K. Isobe, J. Tamaru, Shigeo Nakamura, K. Harigaya +2 more
2002Leukemia and Lymphoma17 citations
Semantic Scholar
Potential use of serum CD44 as an indicator of tumour progression in acute leukemia
A. Yokota, G. Ishii, Yoshiki Sugaya, Miki Nishimura +2 more
1999Hematological Oncology17 citations
Semantic Scholar
Vasospastic Angina in a 13-Year-Old Female Patient Whose Only Symptom Was Toothache
Y. Okajima, Aizan Hirai, Morihiro Higashi, K. Harigaya
2007Pediatric Cardiology16 citations
Semantic Scholar
Interleukin-6 (IL-6) production in carcinoma of the cervix
H. Takanol, K. Harigaya, G. Ishii, Y. Sugaya +8 more
2005Archives of Gynecology and Obstetrics16 citations
Semantic Scholar
Comedonecrosis is an unfavorable marker in node‐negative invasive breast carcinoma
H. Yagata, K. Harigaya, Masato Suzuki, T. Nagashima +5 more
2003Pathology international (Print)16 citations
Semantic Scholar
Correlation between Production of Colony-Stimulating Activity (CSA) and Adipose Conversion in a Murine Marrow-Derived Preadipocyte Line (H-1/A) 1
M. Nakamura, K. Harigaya, Yonosuke Watanabe
1985Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine16 citations
Semantic Scholar
Fibronectin promotes cell proliferation of human pre-B cell line via its interactions with VLA-4 and VLA-5
A. Harima, C. Nakaseko, A. Yokota, M. Kitagawa +3 more
2008Hematology15 citations Open access
Semantic Scholar
Unexpected serum level of vancomycin after oral administration in a patient with severe colitis and renal insufficiency.
Shingo Yamazaki, Hiroyoshi Nakamura, S. Yamagata, Go Miura +9 more
2009International journal of clinical pharmacology and therapeutics13 citations
Semantic Scholar
A burst-promoting activity derived from the human bone marrow stromal cell line KM-102 is identical to the granulocyte-macrophage colony-stimulating factor.
T. Kohama, H. Handa, K. Harigaya
1988Experimental Hematology13 citations
Semantic Scholar

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M. Kitagawa×14
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M. Kitagawa — researcher profile on SciRah
Morihiro Higashi×9
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G. Ishii×8
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Hidetada Kawana×6
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Toshinao Oyama×4

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Akihiro Toyoda×4

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Kazuhiko Azuma×3

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Y. Saito — researcher profile on SciRah

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M. Miyazaki — researcher profile on SciRah

Takeshi Sasamura×2

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Takeshi Sasamura — researcher profile on SciRah