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F. Grahammer · SciRah

Researcher profile · Semantic Scholar

F. Grahammer

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F. Grahammer — researcher profile on SciRah

h-index: 45
Works: 129
Citations: 6,489

Most-cited papers

Autophagy influences glomerular disease susceptibility and maintains podocyte homeostasis in aging mice.
B. Hartleben, Markus Gödel, C. Meyer-Schwesinger, Shuya Liu +13 more
2010Journal of Clinical Investigation712 citations Open access
Semantic Scholar
The podocyte slit diaphragm—from a thin grey line to a complex signalling hub
F. Grahammer, C. Schell, T. Huber
2013Nature Reviews Nephrology262 citations
Semantic Scholar
Autoantibodies Targeting Nephrin in Podocytopathies.
Felicitas E. Hengel, Silke Dehde, Moritz Lassé, G. Zahner +31 more
2024New England Journal of Medicine226 citations
Semantic Scholar
ANKS6 is a central component of a nephronophthisis module linking NEK8 to INVS and NPHP3
Sylvia Hoff, J. Halbritter, Daniel Epting, V. Frank +37 more
2013Nature Genetics201 citations Open access
Semantic Scholar
Roles of mTOR complexes in the kidney: implications for renal disease and transplantation
D. Fantus, N. Rogers, F. Grahammer, T. Huber +1 more
2016Nature Reviews Nephrology185 citations Open access
Semantic Scholar
Unraveling the role of podocyte turnover in glomerular aging and injury.
N. Wanner, B. Hartleben, N. Herbach, Markus Goedel +6 more
2014Journal of the American Society of Nephrology185 citations Open access
Semantic Scholar
CD2AP in mouse and human podocytes controls a proteolytic program that regulates cytoskeletal structure and cellular survival.
S. Yaddanapudi, Mehmet M. Altintas, A. Kistler, Isabel Fernandez +23 more
2011Journal of Clinical Investigation153 citations Open access
Semantic Scholar
Molecular fingerprinting of the podocyte reveals novel gene and protein regulatory networks.
M. Boerries, F. Grahammer, Sven Eiselein, M. Buck +13 more
2013Kidney International146 citations Open access
Semantic Scholar
Thrombospondin type-1 domain-containing 7A in idiopathic membranous nephropathy.
Markus Gödel, F. Grahammer, T. Huber
2015New England Journal of Medicine138 citations
Semantic Scholar
Direct reprogramming of fibroblasts into renal tubular epithelial cells by defined transcription factors
Michael M. Kaminski, J. Tosic, C. Kresbach, H. Engel +9 more
2016Nature Cell Biology120 citations
Semantic Scholar
A Multi-layered Quantitative In Vivo Expression Atlas of the Podocyte Unravels Kidney Disease Candidate Genes
M. Rinschen, Markus Gödel, F. Grahammer, S. Zschiedrich +23 more
2018Cell Reports104 citations Open access
Semantic Scholar
mTORC1 maintains renal tubular homeostasis and is essential in response to ischemic stress
F. Grahammer, Nora Haenisch, Frederic Steinhardt, Lukas Sandner +14 more
2014Proceedings of the National Academy of Sciences of the United States of America98 citations Open access
Semantic Scholar
mTOR Regulates Endocytosis and Nutrient Transport in Proximal Tubular Cells.
F. Grahammer, S. Ramakrishnan, Markus M. Rinschen, A. Larionov +14 more
2017Journal of the American Society of Nephrology91 citations Open access
Semantic Scholar
Renal Atp6ap2/(Pro)renin Receptor Is Required for Normal Vacuolar H+-ATPase Function but Not for the Renin-Angiotensin System.
F. Trepiccione, Simon D. Gerber, F. Grahammer, Karen I. López-Cayuqueo +11 more
2016Journal of the American Society of Nephrology90 citations Open access
Semantic Scholar
Cilia‐localized LKB1 regulates chemokine signaling, macrophage recruitment, and tissue homeostasis in the kidney
Amandine Viau, F. Bienaimé, Kamile Lukas, Abhijeet P. Todkar +23 more
2018EMBO Journal88 citations Open access
Semantic Scholar
A flexible, multilayered protein scaffold maintains the slit in between glomerular podocytes
F. Grahammer, C. Wigge, C. Schell, O. Kretz +19 more
2016JCI Insight88 citations Open access
Semantic Scholar
YAP-mediated mechanotransduction determines the podocyte’s response to damage
Markus M. Rinschen, F. Grahammer, Ann-Kathrin Hoppe, Priyanka Kohli +14 more
2017Science Signaling87 citations
Semantic Scholar
Absence of miR-146a in Podocytes Increases Risk of Diabetic Glomerulopathy via Up-regulation of ErbB4 and Notch-1*
Ha Won Lee, Samia Q. Khan, S. Khaliqdina, Mehmet M. Altintas +16 more
2016Journal of Biological Chemistry87 citations Open access
Semantic Scholar
The tetraspanin CD9 controls migration and proliferation of parietal epithelial cells and glomerular disease progression
H. Lazareth, Carole Hénique, O. Lenoir, Victor G. Puelles +29 more
2019Nature Communications80 citations Open access
Semantic Scholar
A Conformational Change in C-Reactive Protein Enhances Leukocyte Recruitment and Reactive Oxygen Species Generation in Ischemia/Reperfusion Injury
J. R. Thiele, J. Zeller, J. Kiefer, D. Braig +10 more
2018Frontiers in Immunology73 citations Open access
Semantic Scholar
NorUrsodeoxycholic acid ameliorates cholemic nephropathy in bile duct ligated mice.
E. Krones, K. Eller, M. Pollheimer, S. Racedo +11 more
2017Journal of Hepatology66 citations
Semantic Scholar
DNA Methyltransferase 1 Controls Nephron Progenitor Cell Renewal and Differentiation.
N. Wanner, J. Vornweg, Alexander N. Combes, Sean B. Wilson +17 more
2018Journal of the American Society of Nephrology65 citations Open access
Semantic Scholar
N-wasp is required for stabilization of podocyte foot processes.
C. Schell, Lisa Baumhakl, Sarah Salou, A. Conzelmann +9 more
2013Journal of the American Society of Nephrology64 citations Open access
Semantic Scholar
The FERM protein EPB41L5 regulates actomyosin contractility and focal adhesion formation to maintain the kidney filtration barrier
C. Schell, M. Rogg, Martina Suhm, M. Helmstädter +18 more
2017Proceedings of the National Academy of Sciences of the United States of America62 citations Open access
Semantic Scholar
Primary decidual zone formation requires Scribble for pregnancy success in mice
Jia Yuan, S. Aikawa, Wenbo Deng, A. Bartos +5 more
2019Nature Communications61 citations Open access
Semantic Scholar
mTOR controls kidney epithelia in health and disease.
F. Grahammer, N. Wanner, T. Huber
2014Nephrology, Dialysis and Transplantation59 citations
Semantic Scholar
Proteinuric chronic kidney disease is associated with altered red blood cell lifespan, deformability and metabolism.
Rosi Bissinger, T. Nemkov, Angelo D'Alessandro, Marijke Grau +21 more
2021Kidney International58 citations Open access
Semantic Scholar
Single-nephron proteomes connect morphology and function in proteinuric kidney disease.
M. Höhne, Christian K. Frese, F. Grahammer, C. Dafinger +20 more
2018Kidney International57 citations Open access
Semantic Scholar
Genetic and pharmacological inhibition of microRNA-92a maintains podocyte cell cycle quiescence and limits crescentic glomerulonephritis
Carole Hénique, Guillaume Bollée, Xavier Loyer, F. Grahammer +21 more
2017Nature Communications57 citations Open access
Semantic Scholar
A slit-diaphragm-associated protein network for dynamic control of renal filtration
Maciej K. Kocylowski, Hande Aypek, W. Bildl, M. Helmstädter +18 more
2022Nature Communications54 citations Open access
Semantic Scholar
CXCL12 and MYC control energy metabolism to support adaptive responses after kidney injury
T. Yakulov, Abhijeet P. Todkar, K. Slanchev, Johannes Wiegel +16 more
2018Nature Communications51 citations Open access
Semantic Scholar
ARP3 Controls the Podocyte Architecture at the Kidney Filtration Barrier
C. Schell, B. Sabass, M. Helmstaedter, Felix Geist +13 more
2018Developmental Cell51 citations Open access
Semantic Scholar
Deoxycorticosterone Acetate/Salt–Induced Cardiac But Not Renal Injury Is Mediated By Endothelial Mineralocorticoid Receptors Independently From Blood Pressure
A. Lother, D. Fürst, Stella Bergemann, R. Gilsbach +6 more
2016HYPERTENSION48 citations Open access
Semantic Scholar
mTORC2 critically regulates renal potassium handling.
F. Grahammer, V. Nesterov, Azaz Ahmed, Frederic Steinhardt +11 more
2016Journal of Clinical Investigation47 citations Open access
Semantic Scholar
Single-cell transcriptomics reveals a mechanosensitive injury signaling pathway in early diabetic nephropathy
Shuya Liu, Yu Zhao, Shun Lu, Tian-Ran Zhang +20 more
2022bioRxiv45 citations Open access
Semantic Scholar
N-Degradomic Analysis Reveals a Proteolytic Network Processing the Podocyte Cytoskeleton.
M. Rinschen, Ann-Kathrin Hoppe, F. Grahammer, M. Kann +12 more
2017Journal of the American Society of Nephrology42 citations Open access
Semantic Scholar
An integrated organoid omics map extends modeling potential of kidney disease
Moritz Lassé, J. El-Saghir, C. Berthier, S. Eddy +36 more
2023Nature Communications40 citations Open access
Semantic Scholar
Accumulation of α-synuclein mediates podocyte injury in Fabry nephropathy
Fabian Braun, A. Abed, D. Sellung, M. Rogg +34 more
2023Journal of Clinical Investigation39 citations Open access
Semantic Scholar
Renal proximal tubular epithelial cells exert immunomodulatory function by driving inflammatory CD4+ T cell responses.
P. Breda, T. Wiech, C. Meyer-Schwesinger, F. Grahammer +4 more
2019AJP - Renal Physiology34 citations
Semantic Scholar
Expansion-enhanced super-resolution radial fluctuations enable nanoscale molecular profiling of pathology specimens
Dominik Kylies, Marina Zimmermann, Fabian Haas, M. Schwerk +33 more
2023Nature Nanotechnology32 citations Open access
Semantic Scholar
Plasminogen deficiency does not prevent sodium retention in a genetic mouse model of experimental nephrotic syndrome
Meng-Yun Xiao, Bernhard N. Bohnert, Hande Aypek, O. Kretz +11 more
2020Acta Physiologica28 citations Open access
Semantic Scholar
Podocyte regeneration: who can become a podocyte?
F. Grahammer, N. Wanner, T. Huber
2013American Journal of Pathology28 citations Open access
Semantic Scholar
Loss of the collagen IV modifier prolyl 3-hydroxylase 2 causes thin basement membrane nephropathy
Hande Aypek, C. Krisp, Shun Lu, Shuya Liu +18 more
2022Journal of Clinical Investigation27 citations Open access
Semantic Scholar
New structural insights into podocyte biology
F. Grahammer
2017Cell and Tissue Research27 citations Open access
Semantic Scholar
Proteome Analysis of Isolated Podocytes Reveals Stress Responses in Glomerular Sclerosis.
Sybille Koehler, Alexander Kuczkowski, Lucas Kuehne, C. Jüngst +10 more
2020Journal of the American Society of Nephrology24 citations Open access
Semantic Scholar
The WD40-domain containing protein CORO2B is specifically enriched in glomerular podocytes and regulates the ventral actin cytoskeleton
M. Rogg, M. Yasuda-Yamahara, A. Abed, P. Dinse +10 more
2017Scientific Reports24 citations Open access
Semantic Scholar
Nephrin Contributes to Insulin Secretion and Affects Mammalian Target of Rapamycin Signaling Independently of Insulin Receptor.
Rodrigo Villarreal, A. Mitrofanova, D. Maiguel, Ximena Morales +14 more
2016Journal of the American Society of Nephrology24 citations Open access
Semantic Scholar
MAGI-1 Interacts with Nephrin to Maintain Slit Diaphragm Structure through Enhanced Rap1 Activation in Podocytes
J. Ni, Su-Jin Bao, Ruth I. Johnson, Bingbing Zhu +10 more
2016Journal of Biological Chemistry24 citations Open access
Semantic Scholar
ANKS 6 is a central component of a nephronophthisis module linking NEK 8 to INVS and NPHP 3
Sylvia Hoff, J. Halbritter, Daniel Epting, V. Frank +42 more
201323 citations
Semantic Scholar
The Rapamycin-Sensitive Complex of Mammalian Target of Rapamycin Is Essential to Maintain Male Fertility.
C. Schell, O. Kretz, W. Liang, Betina Kiefer +10 more
2016American Journal of Pathology22 citations Open access
Semantic Scholar

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O. Kretz×16
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M. Helmstädter

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