Researcher profile · Semantic Scholar

R. Jacobsen

h-index: 21
Works: 31
Citations: 1,666

Most-cited papers

α-Conotoxin AuIB Selectively Blocks α3β4 Nicotinic Acetylcholine Receptors and Nicotine-Evoked Norepinephrine Release
Si-Qin Luo, J. M. Kulak, G. Cartier, R. Jacobsen +3 more
1998Journal of Neuroscience282 citations Open access
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μ-Conotoxin PIIIA, a New Peptide for Discriminating among Tetrodotoxin-Sensitive Na Channel Subtypes
K. Shon, B. Olivera, M. Watkins, R. Jacobsen +7 more
1998Journal of Neuroscience146 citations Open access
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κ-Conotoxin Pviia Is a Peptide Inhibiting theShaker K+ Channel*
K. Shon, M. Stocker, H. Terlau, W. Stühmer +7 more
1998Journal of Biological Chemistry138 citations Open access
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The T-superfamily of Conotoxins*
Craig S. Walker, D. Steel, R. Jacobsen, Marcelina B. Lirazan +9 more
1999Journal of Biological Chemistry121 citations Open access
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Inactivation of a serotonin-gated ion channel by a polypeptide toxin from marine snails.
Laura England, J. Imperial, R. Jacobsen, A. Craig +5 more
1998Science115 citations
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Definition of the M-conotoxin superfamily: characterization of novel peptides from molluscivorous Conus venoms.
G. P. Corpuz, R. Jacobsen, E. C. Jimenez, M. Watkins +11 more
2005Biochemistry98 citations
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A noncompetitive peptide inhibitor of the nicotinic acetylcholine receptor from Conus purpurascens venom.
K. Shon, Michelle Grilley, R. Jacobsen, G. Cartier +8 more
1997Biochemistry78 citations
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The contryphans, a D-tryptophan-containing family of Conus peptides: interconversion between conformers.
R. Jacobsen, E. C. Jimenez, Michelle Grilley, M. Watkins +3 more
2009Journal of Peptide Research77 citations
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Differential Targeting of Nicotinic Acetylcholine Receptors by Novel αA-Conotoxins*
R. Jacobsen, D. Yoshikami, M. Ellison, Jennifer S. Martinez +7 more
1997Journal of Biological Chemistry68 citations Open access
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alpha-conotoxin AuIB selectively blocks alpha3 beta4 nicotinic acetylcholine receptors and nicotine-evoked norepinephrine release.
Shujun Luo, J. M. Kulak, G. Cartier, R. Jacobsen +3 more
1998Journal of Neuroscience67 citations
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A novel D-leucine-containing Conus peptide: diverse conformational dynamics in the contryphan family.
R. Jacobsen, E. C. Jimenez, R. D. L. De la Cruz, W. R. Gray +2 more
1999Journal of Peptide Research63 citations
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Single Amino Acid Substitutions in κ-Conotoxin PVIIA Disrupt Interaction with the Shaker K+ Channel*
R. Jacobsen, E. D. Koch, Bettina Lange-Malecki, M. Stocker +5 more
2000Journal of Biological Chemistry58 citations Open access
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Structure and dynamics of dark‐state bovine rhodopsin revealed by chemical cross‐linking and high‐resolution mass spectrometry
R. Jacobsen, K. Sale, Marites J. Ayson, P. Novák +6 more
2006Protein Science51 citations Open access
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A novel alpha conotoxin (alpha-PIB) isolated from C. purpurascens is selective for skeletal muscle nicotinic acetylcholine receptors.
E. López-Vera, R. Jacobsen, M. Ellison, B. Olivera +1 more
2007Toxicon44 citations
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Critical residues influence the affinity and selectivity of alpha-conotoxin MI for nicotinic acetylcholine receptors.
R. Jacobsen, R. DelaCruz, Julianne H. Grose, J. McIntosh +2 more
1999Biochemistry44 citations
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Unambiguous assignment of intramolecular chemical cross-links in modified mammalian membrane proteins by Fourier transform-tandem mass spectrometry.
P. Novák, W. Haskins, Marites J. Ayson, R. Jacobsen +4 more
2005Analytical Chemistry42 citations
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Characterization and three-dimensional structure determination of psi-conotoxin Piiif, a novel noncompetitive antagonist of nicotinic acetylcholine receptors.
R. V. van Wagoner, R. Jacobsen, B. Olivera, C. Ireland
2003Biochemistry36 citations
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Escherichia coli signal peptide peptidase A is a serine-lysine protease with a lysine recruited to the nonconserved amino-terminal domain in the S49 protease family.
Peng Wang, Eunjung Shim, B. Cravatt, R. Jacobsen +4 more
2008Biochemistry32 citations Open access
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Solution Conformation of α-Conotoxin EI, a Neuromuscular Toxin Specific for the α1/δ Subunit Interface of Torpedo Nicotinic Acetylcholine Receptor*
K. Park, J. Suk, R. Jacobsen, W. Gray +2 more
2001Journal of Biological Chemistry32 citations Open access
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A novel protein crosslinking reagent for the determination of moderate resolution protein structures by mass spectrometry (MS3-D).
N. Fujii, R. Jacobsen, N. Wood, J. Schoeniger +1 more
2004Bioorganic & Medicinal Chemistry Letters29 citations
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Discovery and characterization of the short kappaA-conotoxins: a novel subfamily of excitatory conotoxins.
Russell W. Teichert, R. Jacobsen, H. Terlau, D. Yoshikami +1 more
2007Toxicon26 citations Open access
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Solution conformation of alpha-conotoxin EI, a neuromuscular toxin specific for the alpha 1/delta subunit interface of torpedo nicotinic acetylcholine receptor.
K. Park, J. Suk, R. Jacobsen, W. Gray +2 more
2001Journal of Biological Chemistry10 citations
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a-Conotoxin Au I B Selectively Blocks a 3 b 4 Nicotinic Acetylcholine Receptors and Nicotine-Evoked Norepinephrine Release
Si-Qin Luo, J. M. Kulak, G. Cartier, R. Jacobsen +3 more
19986 citations
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Protein Structure and Conformation Revealed Using Sequential Cross-linker Rate Measurements (SCRaM): Direct Measurement of Inter-Residue Distances and Secondary Structure.
J. Schoeniger, R. Jacobsen, K. Sale
20072 citations
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Erratum: The T-superfamily of conotoxins (Journal of Biological Chemistry (1999) (30664-30671))
Craig S. Walker, D. Steel, R. Jacobsen, M. Lirazan +9 more
19991 citations
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Dynamical effects of incorporating site-specific crosslinks in peptides examined by hydrogen-deuterium exchange mass spectrometry.
Eizadora T. Yu, Sidney P. Elmer, D. Sasaki, K. Sale +3 more
20100 citations
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Phase-sensitive detection of non-covalent complexes using time modulated ligand delivery.
James Brennan, R. Jacobsen, Marites J. Ayson, J. Schoeniger
20070 citations
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Chemical crosslinking and mass spectrometry studies of the structure and dynamics of membrane proteins and receptors.
W. Haskins, M. Leavell, Pamela D. Lane, R. Jacobsen +8 more
20050 citations Open access
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The interfacial bioscience grand challenge.
Pamela D. Lane, M. Stevens, R. Jacobsen, Joohee Hong +11 more
20040 citations Open access
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NMR Structue of alpha-conotoxin EI
K. Park, J. Suk, R. Jacobsen, W. Gray +2 more
20030 citations
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Mapping membrane protein interactions in cell signaling systems.
Yooli K. Light, M. Hadi, Pamela D. Lane, R. Jacobsen +5 more
20030 citations Open access
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W. Gray

×7

Marites J. Ayson×6

G. Cartier×5

M. Watkins×5

B. M. Olivera×5

K. Sale×5

N. Wood×5

M. Young×5