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J. V. Van Vranken · SciRah

Researcher profile · Semantic Scholar

J. V. Van Vranken

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J. V. Van Vranken — researcher profile on SciRah

h-index: 19
Works: 48
Citations: 3,032

Most-cited papers

A Mitochondrial Pyruvate Carrier Required for Pyruvate Uptake in Yeast, Drosophila, and Humans
Daniel K. Bricker, Eric B. Taylor, John C. Schell, Thomas Orsak +12 more
2012Science837 citations Open access
Semantic Scholar
TMTpro reagents: a set of isobaric labeling mass tags enables simultaneous proteome-wide measurements across 16 samples
Jiaming Li, J. V. Van Vranken, L. P. Vaites, Devin K. Schweppe +12 more
2020Nature Methods420 citations Open access
Semantic Scholar
A role for the mitochondrial pyruvate carrier as a repressor of the Warburg Effect and colon cancer cell growth
John C. Schell, Kristofor A. Olson, Lei Jiang, Amy J. Hawkins +6 more
2014Molecules and Cells345 citations Open access
Semantic Scholar
The mitochondrial acyl carrier protein (ACP) coordinates mitochondrial fatty acid synthesis with iron sulfur cluster biogenesis
J. V. Van Vranken, Mi-Young Jeong, Peng Wei, Yu-Chan Chen +3 more
2016eLife149 citations Open access
Semantic Scholar
Structure of human Fe–S assembly subcomplex reveals unexpected cysteine desulfurase architecture and acyl-ACP–ISD11 interactions
S. A. Cory, J. V. Van Vranken, E. Brignole, Shachin Patra +4 more
2017Proceedings of the National Academy of Sciences of the United States of America144 citations Open access
Semantic Scholar
Amelioration of pathologic α-synuclein-induced Parkinson’s disease by irisin
Tae-In Kam, Hyejin Park, Shih-Ching Chou, J. V. Van Vranken +13 more
2022Proceedings of the National Academy of Sciences of the United States of America122 citations Open access
Semantic Scholar
A proteome-wide atlas of drug mechanism of action
Dylan C. Mitchell, Miljan Kuljanin, Jiaming Li, J. V. Van Vranken +4 more
2023Nature Biotechnology117 citations Open access
Semantic Scholar
Protein-mediated assembly of succinate dehydrogenase and its cofactors
J. V. Van Vranken, U. Na, D. Winge, J. Rutter
2014Critical reviews in biochemistry and molecular biology116 citations Open access
Semantic Scholar
SDHAF4 promotes mitochondrial succinate dehydrogenase activity and prevents neurodegeneration
J. V. Van Vranken, Daniel K. Bricker, Noah E. Dephoure, S. Gygi +3 more
2014Cell Metabolism104 citations Open access
Semantic Scholar
Vms1p is a release factor for the ribosome-associated quality control complex
Olga Zurita Rendón, Eric K. Fredrickson, Conor J. Howard, J. V. Van Vranken +8 more
2018Nature Communications96 citations Open access
Semantic Scholar
ACP acylation is an acetyl-CoA-dependent modification required for electron transport chain assembly
J. V. Van Vranken, S. Nowinski, Katie J. Clowers, Mi-Young Jeong +6 more
2018Molecules and Cells95 citations Open access
Semantic Scholar
Mitochondrial Fatty Acid Synthesis is the puppet master of mitochondrial biogenesis
S. Nowinski, J. V. Van Vranken, K. Dove, J. Rutter
2018Current Biology80 citations Open access
Semantic Scholar
Isolation of extracellular fluids reveals novel secreted bioactive proteins from muscle and fat tissues
Melanie J. Mittenbühler, Mark P. Jedrychowski, J. V. Van Vranken, Hans-Georg Sprenger +12 more
2023Cell Metabolism63 citations Open access
Semantic Scholar
Ergothioneine controls mitochondrial function and exercise performance via direct activation of MPST.
Hans-Georg Sprenger, Melanie J. Mittenbühler, Yizhi Sun, J. V. Van Vranken +24 more
2025Cell Metabolism57 citations
Semantic Scholar
Assessing target engagement using proteome-wide solvent shift assays
J. V. Van Vranken, Jiaming Li, Dylan C. Mitchell, José Navarrete-Perea +1 more
2021bioRxiv44 citations Open access
Semantic Scholar
Selection of Heating Temperatures Improves the Sensitivity of the Proteome Integral Solubility Alteration Assay
Jiaming Li, J. V. Van Vranken, João A. Paulo, Edward L. Huttlin +1 more
2020Journal of Proteome Research42 citations Open access
Semantic Scholar
RBM43 controls PGC1α translation and a PGC1α-STING signaling axis
Phillip A. Dumesic, Sarah E. Wilensky, Symanthika Bose, J. V. Van Vranken +2 more
2025Cell Metabolism23 citations Open access
Semantic Scholar
Mustn1 is a smooth muscle cell-secreted microprotein that modulates skeletal muscle extracellular matrix composition
Serge Ducommun, P. Jannig, I. Cervenka, M. Murgia +18 more
2024Molecular Metabolism21 citations Open access
Semantic Scholar
Phosphate starvation signaling increases mitochondrial membrane potential through respiration-independent mechanisms
Ye-Yun Ouyang, Mi-Young Jeong, Corey N. Cunningham, J. A. Berg +16 more
2022bioRxiv21 citations Open access
Semantic Scholar
Large-scale characterization of drug mechanism of action using proteome-wide thermal shift assays
J. V. Van Vranken, Jiaming Li, J. Mintseris, Meagan Gadzuk-Shea +2 more
2024bioRxiv18 citations Open access
Semantic Scholar
You Down With ETC? Yeah, You Know D!
J. V. Van Vranken, J. Rutter
2015Cell18 citations Open access
Semantic Scholar
Derepressing nuclear pyruvate dehydrogenase induces therapeutic cancer cell reprogramming.
Ting Zhao, Lingli He, L. Wong, Sheng-Lin Mei +18 more
2025Cell Metabolism13 citations
Semantic Scholar
Selection of Heating Temperatures Improves the Sensitivity of the Proteome Integral Solubility Alteration Assay
Jiaming Li, J. V. Van Vranken
202012 citations Open access
Semantic Scholar
Large-scale characterization of drug mechanism of action using proteome-wide thermal shift assays
J. V. Van Vranken, Jiaming Li, J. Mintseris, Ting-Yu Wei +4 more
2024eLife11 citations Open access
Semantic Scholar
Insulin sensitization by small molecules enhancing GLUT4 translocation
Terry C. Yin, J. V. Van Vranken, D. Srivastava, Ayushi Mittal +10 more
2023Cell Chemical Biology11 citations Open access
Semantic Scholar
Therapeutic Remodeling of the Ceramide Backbone Prevents Kidney Injury
Rebekah Nicholson, L. Cedeño-Rosario, J. Maschek, Trevor Lonergan +24 more
2025Cell Metabolism10 citations Open access
Semantic Scholar
The Whole (Cell) Is Less Than the Sum of Its Parts
J. V. Van Vranken, J. Rutter
2016Cell9 citations Open access
Semantic Scholar
Ergothioneine boosts mitochondrial respiration and exercise performance via direct activation of MPST
Hans-Georg Sprenger, Melanie J. Mittenbühler, Yizhi Sun, J. V. Van Vranken +22 more
2024bioRxiv7 citations Open access
Semantic Scholar
A dual-purification system to isolate mitochondrial subpopulations
Corey N. Cunningham, J. V. Van Vranken, Jakeline Larios, Katarina Heyden +2 more
2025Journal of Cell Science6 citations Open access
Semantic Scholar
Iron Deficiency and Recovery in Yeast: A Quantitative Proteomics Approach
José Navarrete-Perea, A. Guerra-Moreno, J. V. Van Vranken, M. Isasa +2 more
2021Journal of Proteome Research6 citations Open access
Semantic Scholar
Herzig Pyruvate Carrier Identification and Functional Expression of the Mitochondrial
Daniel K. Bricker, Eric B. Taylor, John C. Schell, Thomas Orsak +8 more
20125 citations
Semantic Scholar
Mitochondrial l-2-hydroxyglutarate is a physiological signalling metabolite
R. Chakrabarty, J. V. Van Vranken, Yuki Aoi, Taylor A Poor +25 more
2026Nature4 citations Open access
Semantic Scholar
On-target toxicity limits the efficacy of CDK11 inhibition against cancers with 1p36 deletions
Linda Julian, L. Crozier, Devon A. Lukow, Sanat Mishra +31 more
2025bioRxiv4 citations Open access
Semantic Scholar
RBM43 links adipose inflammation and energy expenditure through translational regulation of PGC1α
Phillip A. Dumesic, Sarah E. Wilensky, Symanthika Bose, J. V. Van Vranken +2 more
2023bioRxiv3 citations Open access
Semantic Scholar
Structure of human Fe–S assembly sub-complex
S. A. Cory, J. V. Van Vranken, E. Brignole, Shachin Patra +4 more
20172 citations Open access
Semantic Scholar
SLC16A6 is a tyrosine transporter for the melanosome
Corey N. Cunningham, Alex J. Bott, Charles H. Adelmann, Matthew Shields +9 more
2026bioRxiv1 citations Open access
Semantic Scholar
Lineage specifying transcription factors determine cell function by direct control of metabolism
Alex J. Bott, Joshua C. Youngs, Corey N. Cunningham, J. V. Van Vranken +5 more
2026bioRxiv1 citations Open access
Semantic Scholar
Exploring the functional role of an ancient mitochondrial fatty acid synthesis pathway
K. Dove, Malika F. Kadirova, S. Nowinski, Ye-Yun Ouyang +2 more
2019The FASEB Journal1 citations
Semantic Scholar
Author response: The mitochondrial acyl carrier protein (ACP) coordinates mitochondrial fatty acid synthesis with iron sulfur cluster biogenesis
J. V. Van Vranken, Mi-Young Jeong, Peng Wei, Yu-Chan Chen +3 more
20161 citations Open access
Semantic Scholar
Microbial metabolism of methotrexate produces a STAT3 signaling molecule that alleviates gut inflammation
Juyeong Cho, R. Danner, Woo Sung Kim, Jonathan Williams +6 more
2026bioRxiv0 citations Open access
Semantic Scholar
Gut microbiome derived folate metabolite suppresses colorectal cancer progression
R. Danner, Juyeong Cho, Z. Detwiler, Jonathan Williams +8 more
2026bioRxiv0 citations Open access
Semantic Scholar
A genetic platform to deconvolve efficacy and toxicity reveals the on-target effects of CDK11 inhibition in vivo
Linda Julian, L. Crozier, Devon A. Lukow, Aditi Swamy +34 more
2026Nature Communications0 citations Open access
Semantic Scholar
Folic acid polyglutamylation triggers MAP2K5 signaling to induce adipocyte lipid catabolism
Woo Sung Kim, R. Danner, Juyeong Cho, Jonathan Williams +12 more
2026bioRxiv0 citations Open access
Semantic Scholar
SUN-647 RBM43 Controls PGC1α Translation and a PGC1α-STING Signaling Axis
Phillip A Dumesic, Sarah E. Wilensky, Symanthika Bose, J. V. Van Vranken +2 more
2025Journal of the Endocrine Society0 citations Open access
Semantic Scholar
Interrupting ELMSAN1 repression of nuclear acetyl-CoA production therapeutically reprograms cancer cells
Ting Zhao, Lingli He, L. Wong, Sheng-Lin Mei +18 more
2025bioRxiv0 citations Open access
Semantic Scholar
Insulin Sensitization by Small Molecules Enhancing GLUT4 Translocation
Terry C. Yin, J. V. Van Vranken, D. Srivastava, Jissele A. Verdinez +7 more
2022Social Science Research Network0 citations
Semantic Scholar
Peer Review #1 of "Comparative analysis of fatty acid metabolism based on transcriptome sequencing of wild and cultivated Ophiocordyceps sinensis (v0.1)"
Han Zhang, Pan Yue, X. Tong, Ting-Hui Gao +179 more
20210 citations Open access
Semantic Scholar
Coordinated Assembly of the Mitochondrial Electron Transport Chain
J. V. Van Vranken
20190 citations
Semantic Scholar
Structure of the human Fe–S cluster assembly sub-complex: implications in Friedreich's ataxia and primary metabolism
S. A. Cory, J. V. Van Vranken, E. Brignole, Shachin Patra +4 more
2018Acta Crystallographica Section A: Foundations and Advances0 citations Open access
Semantic Scholar

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